| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the 1,4-chrysenequinone-7139 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADM | adrenomedullin |
| AKAP17A | A kinase (PRKA) anchor protein 17A |
| ARC | activity-regulated cytoskeleton-associated protein |
| ARG2 | arginase 2 |
| ATF3 | activating transcription factor 3 |
| ATF7IP2 | activating transcription factor 7 interacting protein 2 |
| BAG3 | BCL2-associated athanogene 3 |
| BAMBI | BMP and activin membrane-bound inhibitor |
| C21ORF91 | chromosome 21 open reading frame 91 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CLCN6 | chloride channel, voltage-sensitive 6 |
| CLK1 | CDC-like kinase 1 |
| CLU | clusterin |
| CRYAB | crystallin, alpha B |
| CSRP2 | cysteine and glycine-rich protein 2 |
| CTGF | connective tissue growth factor |
| CXCL3 | chemokine (C-X-C motif) ligand 3 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DLX2 | distal-less homeobox 2 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
| DNAJB4 | DnaJ (Hsp40) homolog, subfamily B, member 4 |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 |
| DUSP1 | dual specificity phosphatase 1 |
| DUSP10 | dual specificity phosphatase 10 |
| DUSP2 | dual specificity phosphatase 2 |
| EFNA5 | ephrin-A5 |
| EGR1 | early growth response 1 |
| EIF5 | eukaryotic translation initiation factor 5 |
| F11R | F11 receptor |
| FAM46A | family with sequence similarity 46, member A |
| FAM46C | family with sequence similarity 46, member C |
| FGFR1 | fibroblast growth factor receptor 1 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B |
| FZD7 | frizzled class receptor 7 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha |
| GADD45B | growth arrest and DNA-damage-inducible, beta |
| GEM | GTP binding protein overexpressed in skeletal muscle |
| HBEGF | heparin-binding EGF-like growth factor |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
| HIST1H3G | histone cluster 1, H3g |
| HMOX1 | heme oxygenase 1 |
| HOPX | HOP homeobox |
| HSPA1A | heat shock 70kDa protein 1A |
| HSPA1L | heat shock 70kDa protein 1-like |
| HSPA2 | heat shock 70kDa protein 2 |
| HSPA4 | heat shock 70kDa protein 4 |
| HSPA4L | heat shock 70kDa protein 4-like |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| HSPB1 | heat shock 27kDa protein 1 |
| HSPB8 | heat shock 22kDa protein 8 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 |
| IER5 | immediate early response 5 |
| INSIG1 | insulin induced gene 1 |
| ISL1 | ISL LIM homeobox 1 |
| JUN | jun proto-oncogene |
| KCNJ2 | potassium channel, inwardly rectifying subfamily J, member 2 |
| KRT6A | keratin 6A, type II |
| KRT6B | keratin 6B, type II |
| LGSN | lengsin, lens protein with glutamine synthetase domain |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MICB | MHC class I polypeptide-related sequence B |
| MMP1 | matrix metallopeptidase 1 |
| MMP10 | matrix metallopeptidase 10 |
| MRPL18 | mitochondrial ribosomal protein L18 |
| MYLIP | myosin regulatory light chain interacting protein |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| NXF1 | nuclear RNA export factor 1 |
| OSR2 | odd-skipped related transciption factor 2 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 |
| PLAUR | plasminogen activator, urokinase receptor |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C |
| RGCC | regulator of cell cycle |
| RHOB | ras homolog family member B |
| RND1 | Rho family GTPase 1 |
| SCGB2A2 | secretoglobin, family 2A, member 2 |
| SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) |
| SGK1 | serum/glucocorticoid regulated kinase 1 |
| SLC3A2 | solute carrier family 3 (amino acid transporter heavy chain), member 2 |
| SLC5A2 | solute carrier family 5 (sodium/glucose cotransporter), member 2 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SMAD7 | SMAD family member 7 |
| SMC4 | structural maintenance of chromosomes 4 |
| SNAPC1 | small nuclear RNA activating complex, polypeptide 1, 43kDa |
| TESPA1 | thymocyte expressed, positive selection associated 1 |
| TNFSF9 | tumor necrosis factor (ligand) superfamily, member 9 |
| TRIM26 | tripartite motif containing 26 |
| TSPYL2 | TSPY-like 2 |
| TUFT1 | tuftelin 1 |
| UROD | uroporphyrinogen decarboxylase |
| USPL1 | ubiquitin specific peptidase like 1 |
| WIPI2 | WD repeat domain, phosphoinositide interacting 2 |
| WIZ | widely interspaced zinc finger motifs |
| ZFP36 | ZFP36 ring finger protein |
| ZMYM5 | zinc finger, MYM-type 5 |
| ZNF473 | zinc finger protein 473 |
| Symbol | Name |
|---|---|
| ACTR8 | ARP8 actin-related protein 8 homolog (yeast) |
| ANKS1A | ankyrin repeat and sterile alpha motif domain containing 1A |
| BAP1 | BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) |
| BCL2L2 | BCL2-like 2 |
| BHLHE40 | basic helix-loop-helix family, member e40 |
| C12ORF29 | chromosome 12 open reading frame 29 |
| C9ORF91 | chromosome 9 open reading frame 91 |
| CAPRIN2 | caprin family member 2 |
| CASD1 | CAS1 domain containing 1 |
| CASP8AP2 | caspase 8 associated protein 2 |
| CCDC69 | coiled-coil domain containing 69 |
| CEP97 | centrosomal protein 97kDa |
| CHMP7 | charged multivesicular body protein 7 |
| CHST2 | carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 |
| CLK2 | CDC-like kinase 2 |
| CROCCP2 | ciliary rootlet coiled-coil, rootletin pseudogene 2 |
| CTDSP1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 |
| DDHD2 | DDHD domain containing 2 |
| DENND4B | DENN/MADD domain containing 4B |
| DIXDC1 | DIX domain containing 1 |
| DNAAF2 | dynein, axonemal, assembly factor 2 |
| DNMBP | dynamin binding protein |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 |
| EML4 | echinoderm microtubule associated protein like 4 |
| EXOC2 | exocyst complex component 2 |
| FBXO5 | F-box protein 5 |
| FOXA1 | forkhead box A1 |
| FZD4 | frizzled class receptor 4 |
| FZD8 | frizzled class receptor 8 |
| GBX2 | gastrulation brain homeobox 2 |
| GMPPA | GDP-mannose pyrophosphorylase A |
| GRAMD1B | GRAM domain containing 1B |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HMGA2 | high mobility group AT-hook 2 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 |
| INPP5E | inositol polyphosphate-5-phosphatase, 72 kDa |
| ITPKB | inositol-trisphosphate 3-kinase B |
| KCTD20 | potassium channel tetramerization domain containing 20 |
| KIF15 | kinesin family member 15 |
| KIF16B | kinesin family member 16B |
| KLHL12 | kelch-like family member 12 |
| KLHL9 | kelch-like family member 9 |
| LOC100272216 | uncharacterized LOC100272216 |
| LPAR6 | lysophosphatidic acid receptor 6 |
| LRIG2 | leucine-rich repeats and immunoglobulin-like domains 2 |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
| MFSD12 | major facilitator superfamily domain containing 12 |
| MGC12488 | |
| MKL2 | MKL/myocardin-like 2 |
| MNT | MAX network transcriptional repressor |
| NACC2 | NACC family member 2, BEN and BTB (POZ) domain containing |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase |
| NINL | ninein-like |
| NLK | nemo-like kinase |
| NSD1 | nuclear receptor binding SET domain protein 1 |
| NUBPL | nucleotide binding protein-like |
| NUDT6 | nudix (nucleoside diphosphate linked moiety X)-type motif 6 |
| OSGEPL1 | O-sialoglycoprotein endopeptidase-like 1 |
| PAGR1 | PAXIP1 associated glutamate-rich protein 1 |
| PALB2 | partner and localizer of BRCA2 |
| PANK4 | pantothenate kinase 4 |
| PARP16 | poly (ADP-ribose) polymerase family, member 16 |
| PAXIP1 | PAX interacting (with transcription-activation domain) protein 1 |
| PCSK7 | proprotein convertase subtilisin/kexin type 7 |
| PIEZO1 | piezo-type mechanosensitive ion channel component 1 |
| PIP5K1C | phosphatidylinositol-4-phosphate 5-kinase, type I, gamma |
| PLEKHJ1 | pleckstrin homology domain containing, family J member 1 |
| POLR1B | polymerase (RNA) I polypeptide B, 128kDa |
| PPP1R13B | protein phosphatase 1, regulatory subunit 13B |
| PRMT7 | protein arginine methyltransferase 7 |
| PTK7 | protein tyrosine kinase 7 (inactive) |
| REV1 | REV1, polymerase (DNA directed) |
| RNF44 | ring finger protein 44 |
| RP2 | retinitis pigmentosa 2 (X-linked recessive) |
| SCML2 | sex comb on midleg-like 2 (Drosophila) |
| SLC25A28 | solute carrier family 25 (mitochondrial iron transporter), member 28 |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) |
| STARD13 | StAR-related lipid transfer (START) domain containing 13 |
| STK25 | serine/threonine kinase 25 |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| TBC1D16 | TBC1 domain family, member 16 |
| TMA16 | translation machinery associated 16 homolog (S. cerevisiae) |
| TRAF5 | TNF receptor-associated factor 5 |
| TRIM13 | tripartite motif containing 13 |
| TRMT12 | tRNA methyltransferase 12 homolog (S. cerevisiae) |
| TULP4 | tubby like protein 4 |
| UBL4A | ubiquitin-like 4A |
| UNC13B | unc-13 homolog B (C. elegans) |
| URB2 | URB2 ribosome biogenesis 2 homolog (S. cerevisiae) |
| USP5 | ubiquitin specific peptidase 5 (isopeptidase T) |
| VANGL1 | VANGL planar cell polarity protein 1 |
| WASF1 | WAS protein family, member 1 |
| WDR37 | WD repeat domain 37 |
| WDR76 | WD repeat domain 76 |
| ZBED8 | zinc finger, BED-type containing 8 |
| ZC3H4 | zinc finger CCCH-type containing 4 |
| ZNF217 | zinc finger protein 217 |
| ZNF451 | zinc finger protein 451 |
