| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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200 genes differentially expressed following the 1,5-isoquinolinediol-543 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACACB | acetyl-CoA carboxylase beta |
| AKR1C1 | aldo-keto reductase family 1, member C1 |
| ALDH6A1 | aldehyde dehydrogenase 6 family, member A1 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 |
| APH1B | APH1B gamma secretase subunit |
| ARHGEF11 | Rho guanine nucleotide exchange factor (GEF) 11 |
| ARIH2 | ariadne RBR E3 ubiquitin protein ligase 2 |
| ATF6 | activating transcription factor 6 |
| BPIFA1 | BPI fold containing family A, member 1 |
| BRE | brain and reproductive organ-expressed (TNFRSF1A modulator) |
| C14ORF1 | chromosome 14 open reading frame 1 |
| C2CD2L | C2CD2-like |
| CACFD1 | calcium channel flower domain containing 1 |
| CAP2 | CAP, adenylate cyclase-associated protein, 2 (yeast) |
| CCNG2 | cyclin G2 |
| CCZ1 | CCZ1 vacuolar protein trafficking and biogenesis associated homolog (S. cerevisiae) |
| CD1A | CD1a molecule |
| CD3E | CD3e molecule, epsilon (CD3-TCR complex) |
| CDIPT | CDP-diacylglycerol--inositol 3-phosphatidyltransferase |
| CDK10 | cyclin-dependent kinase 10 |
| CDK19 | cyclin-dependent kinase 19 |
| CEP41 | centrosomal protein 41kDa |
| CER1 | cerberus 1, DAN family BMP antagonist |
| CETN1 | centrin, EF-hand protein, 1 |
| CHN2 | chimerin 2 |
| CLEC1A | C-type lectin domain family 1, member A |
| CLSPN | claspin |
| CRKL | v-crk avian sarcoma virus CT10 oncogene homolog-like |
| CTNS | cystinosin, lysosomal cystine transporter |
| CYB561 | cytochrome b561 |
| DECR2 | 2,4-dienoyl CoA reductase 2, peroxisomal |
| DSTYK | dual serine/threonine and tyrosine protein kinase |
| DTNA | dystrobrevin, alpha |
| EFNA5 | ephrin-A5 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FAM189A2 | family with sequence similarity 189, member A2 |
| FNTB | farnesyltransferase, CAAX box, beta |
| FOXN3 | forkhead box N3 |
| FSCN3 | fascin actin-bundling protein 3, testicular |
| GM2A | GM2 ganglioside activator |
| GSK3A | glycogen synthase kinase 3 alpha |
| HMX1 | H6 family homeobox 1 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) |
| HTR4 | 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled |
| ING4 | inhibitor of growth family, member 4 |
| INHBC | inhibin, beta C |
| JAK2 | Janus kinase 2 |
| KCNAB1 | potassium channel, voltage gated subfamily A regulatory beta subunit 1 |
| KCNJ5 | potassium channel, inwardly rectifying subfamily J, member 5 |
| KLHL1 | kelch-like family member 1 |
| KRCC1 | lysine-rich coiled-coil 1 |
| LHX3 | LIM homeobox 3 |
| LINC00312 | long intergenic non-protein coding RNA 312 |
| LOC100131510 | uncharacterized LOC100131510 |
| LOC399491 | |
| LRRC15 | leucine rich repeat containing 15 |
| LRRC41 | leucine rich repeat containing 41 |
| MBD3 | methyl-CpG binding domain protein 3 |
| MISP | mitotic spindle positioning |
| MR1 | major histocompatibility complex, class I-related |
| MYO1B | myosin IB |
| MYOC | myocilin, trabecular meshwork inducible glucocorticoid response |
| N4BP2L1 | NEDD4 binding protein 2-like 1 |
| NET1 | neuroepithelial cell transforming 1 |
| NMT1 | N-myristoyltransferase 1 |
| NOS1 | nitric oxide synthase 1 (neuronal) |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 |
| OASL | 2'-5'-oligoadenylate synthetase-like |
| PCDHGB5 | protocadherin gamma subfamily B, 5 |
| PRDM4 | PR domain containing 4 |
| PRIM2 | primase, DNA, polypeptide 2 (58kDa) |
| PRKAG1 | protein kinase, AMP-activated, gamma 1 non-catalytic subunit |
| PSIP1 | PC4 and SFRS1 interacting protein 1 |
| PSMD9 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 9 |
| PXN | paxillin |
| RLBP1 | retinaldehyde binding protein 1 |
| RMND5B | required for meiotic nuclear division 5 homolog B (S. cerevisiae) |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit |
| SH3BP2 | SH3-domain binding protein 2 |
| SIDT2 | SID1 transmembrane family, member 2 |
| SIRT6 | sirtuin 6 |
| SLC25A40 | solute carrier family 25, member 40 |
| SLC31A2 | solute carrier family 31 (copper transporter), member 2 |
| SLN | sarcolipin |
| SPOCK2 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 |
| SSH1 | slingshot protein phosphatase 1 |
| TAF12 | TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa |
| TCAF1 | TRPM8 channel-associated factor 1 |
| TESK2 | testis-specific kinase 2 |
| TIAM2 | T-cell lymphoma invasion and metastasis 2 |
| TMEM184B | transmembrane protein 184B |
| TNFSF9 | tumor necrosis factor (ligand) superfamily, member 9 |
| VPS33B | vacuolar protein sorting 33 homolog B (yeast) |
| WWP2 | WW domain containing E3 ubiquitin protein ligase 2 |
| YPEL1 | yippee-like 1 (Drosophila) |
| ZBTB20 | zinc finger and BTB domain containing 20 |
| ZCCHC24 | zinc finger, CCHC domain containing 24 |
| ZFYVE9 | zinc finger, FYVE domain containing 9 |
| ZNF175 | zinc finger protein 175 |
| Symbol | Name |
|---|---|
| ACD | adrenocortical dysplasia homolog (mouse) |
| ACTN4 | actinin, alpha 4 |
| AP1G2 | adaptor-related protein complex 1, gamma 2 subunit |
| ARRB1 | arrestin, beta 1 |
| ASB13 | ankyrin repeat and SOCS box containing 13 |
| ATXN2 | ataxin 2 |
| BIK | BCL2-interacting killer (apoptosis-inducing) |
| BSCL2 | Berardinelli-Seip congenital lipodystrophy 2 (seipin) |
| C10ORF2 | chromosome 10 open reading frame 2 |
| CA5BP1 | carbonic anhydrase VB pseudogene 1 |
| CA6 | carbonic anhydrase VI |
| CBR1 | carbonyl reductase 1 |
| CCDC86 | coiled-coil domain containing 86 |
| CCDC94 | coiled-coil domain containing 94 |
| CCL2 | chemokine (C-C motif) ligand 2 |
| CD3EAP | CD3e molecule, epsilon associated protein |
| CHST12 | carbohydrate (chondroitin 4) sulfotransferase 12 |
| CLN6 | ceroid-lipofuscinosis, neuronal 6, late infantile, variant |
| CYBRD1 | cytochrome b reductase 1 |
| CYSLTR2 | cysteinyl leukotriene receptor 2 |
| DAZAP1 | DAZ associated protein 1 |
| DDX21 | DEAD (Asp-Glu-Ala-Asp) box helicase 21 |
| DENND4A | DENN/MADD domain containing 4A |
| DIXDC1 | DIX domain containing 1 |
| DLEU2 | deleted in lymphocytic leukemia 2 (non-protein coding) |
| DNAJC2 | DnaJ (Hsp40) homolog, subfamily C, member 2 |
| DUSP2 | dual specificity phosphatase 2 |
| DYNLL1 | dynein, light chain, LC8-type 1 |
| E2F6 | E2F transcription factor 6 |
| EMP2 | epithelial membrane protein 2 |
| ERF | Ets2 repressor factor |
| FCHO1 | FCH domain only 1 |
| FOXRED2 | FAD-dependent oxidoreductase domain containing 2 |
| GBAP1 | glucosidase, beta, acid pseudogene 1 |
| GCNT1 | glucosaminyl (N-acetyl) transferase 1, core 2 |
| GEMIN6 | gem (nuclear organelle) associated protein 6 |
| GPR18 | G protein-coupled receptor 18 |
| HDAC5 | histone deacetylase 5 |
| HDAC9 | histone deacetylase 9 |
| HMHA1 | histocompatibility (minor) HA-1 |
| HSPA8 | heat shock 70kDa protein 8 |
| HSPB1 | heat shock 27kDa protein 1 |
| IFITM3 | interferon induced transmembrane protein 3 |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| IRF8 | interferon regulatory factor 8 |
| ITPKB | inositol-trisphosphate 3-kinase B |
| LAS1L | LAS1-like (S. cerevisiae) |
| LRFN4 | leucine rich repeat and fibronectin type III domain containing 4 |
| MAPKBP1 | mitogen-activated protein kinase binding protein 1 |
| MED4 | mediator complex subunit 4 |
| MFHAS1 | malignant fibrous histiocytoma amplified sequence 1 |
| MFSD12 | major facilitator superfamily domain containing 12 |
| MMACHC | methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria |
| MRPL33 | mitochondrial ribosomal protein L33 |
| MRTO4 | mRNA turnover 4 homolog (S. cerevisiae) |
| MT1HL1 | metallothionein 1H-like 1 |
| MYBBP1A | MYB binding protein (P160) 1a |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| NVL | nuclear VCP-like |
| OBFC1 | oligonucleotide/oligosaccharide-binding fold containing 1 |
| PAK1IP1 | PAK1 interacting protein 1 |
| PELP1 | proline, glutamate and leucine rich protein 1 |
| PFAS | phosphoribosylformylglycinamidine synthase |
| PIBF1 | progesterone immunomodulatory binding factor 1 |
| PMM2 | phosphomannomutase 2 |
| PPIEL | peptidylprolyl isomerase E-like pseudogene |
| PRMT7 | protein arginine methyltransferase 7 |
| PTCD2 | pentatricopeptide repeat domain 2 |
| PUS7 | pseudouridylate synthase 7 (putative) |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 |
| RRP9 | ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast) |
| SCO2 | SCO2 cytochrome c oxidase assembly protein |
| SDCCAG3 | serologically defined colon cancer antigen 3 |
| SERINC5 | serine incorporator 5 |
| SH3GL1 | SH3-domain GRB2-like 1 |
| SLAMF7 | SLAM family member 7 |
| SLC10A3 | solute carrier family 10, member 3 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 |
| SLC29A2 | solute carrier family 29 (equilibrative nucleoside transporter), member 2 |
| SMPDL3A | sphingomyelin phosphodiesterase, acid-like 3A |
| SREBF1 | sterol regulatory element binding transcription factor 1 |
| SSSCA1 | Sjogren syndrome/scleroderma autoantigen 1 |
| STEAP3 | STEAP family member 3, metalloreductase |
| TET3 | tet methylcytosine dioxygenase 3 |
| TFB2M | transcription factor B2, mitochondrial |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) |
| TMPRSS6 | transmembrane protease, serine 6 |
| TNS3 | tensin 3 |
| TOE1 | target of EGR1, member 1 (nuclear) |
| TRABD | TraB domain containing |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 |
| UBIAD1 | UbiA prenyltransferase domain containing 1 |
| UNC93B1 | unc-93 homolog B1 (C. elegans) |
| USP20 | ubiquitin specific peptidase 20 |
| USP39 | ubiquitin specific peptidase 39 |
| USP48 | ubiquitin specific peptidase 48 |
| WDR3 | WD repeat domain 3 |
| WDR43 | WD repeat domain 43 |
| WDR46 | WD repeat domain 46 |
| ZNF185 | zinc finger protein 185 (LIM domain) |
