10-methoxyharmalan-5455 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
Similar Terms
Downloads & Tools

Genes

195 genes differentially expressed following the 10-methoxyharmalan-5455 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACSL5 acyl-CoA synthetase long-chain family member 5
ADRBK1 adrenergic, beta, receptor kinase 1
ANGPT4 angiopoietin 4
ANGPTL2 angiopoietin-like 2
ANGPTL7 angiopoietin-like 7
ANKRD7 ankyrin repeat domain 7
ANTXR1 anthrax toxin receptor 1
ARHGAP1 Rho GTPase activating protein 1
ARHGAP26 Rho GTPase activating protein 26
ATAT1 alpha tubulin acetyltransferase 1
ATP11A ATPase, class VI, type 11A
AURKC aurora kinase C
BCAT1 branched chain amino-acid transaminase 1, cytosolic
CASP1 caspase 1, apoptosis-related cysteine peptidase
CCRL2 chemokine (C-C motif) receptor-like 2
CDRT1 CMT1A duplicated region transcript 1
CHN2 chimerin 2
CNOT3 CCR4-NOT transcription complex, subunit 3
CXCR4 chemokine (C-X-C motif) receptor 4
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYP4F11 cytochrome P450, family 4, subfamily F, polypeptide 11
DDX51 DEAD (Asp-Glu-Ala-Asp) box polypeptide 51
DEFB4A defensin, beta 4A
DGCR9 DiGeorge syndrome critical region gene 9 (non-protein coding)
DOCK5 dedicator of cytokinesis 5
DPF1 D4, zinc and double PHD fingers family 1
DTNA dystrobrevin, alpha
DUSP9 dual specificity phosphatase 9
EPHB2 EPH receptor B2
FAM182B family with sequence similarity 182, member B
FAM214B family with sequence similarity 214, member B
FGF1 fibroblast growth factor 1 (acidic)
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GOLGA8A golgin A8 family, member A
GPR137 G protein-coupled receptor 137
HCG4 HLA complex group 4 (non-protein coding)
IFIT5 interferon-induced protein with tetratricopeptide repeats 5
IL9R interleukin 9 receptor
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1
KIAA0319L KIAA0319-like
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KXD1 KxDL motif containing 1
LMAN1 lectin, mannose-binding, 1
MAL mal, T-cell differentiation protein
MAOB monoamine oxidase B
MAP4 microtubule-associated protein 4
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MFGE8 milk fat globule-EGF factor 8 protein
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MUC3B mucin 3B, cell surface associated
MYL10 myosin, light chain 10, regulatory
NDOR1 NADPH dependent diflavin oxidoreductase 1
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NR6A1 nuclear receptor subfamily 6, group A, member 1
NTF3 neurotrophin 3
NUP188 nucleoporin 188kDa
NUP88 nucleoporin 88kDa
OLFML2B olfactomedin-like 2B
PAIP2B poly(A) binding protein interacting protein 2B
PCDHGB5 protocadherin gamma subfamily B, 5
PCM1 pericentriolar material 1
PCSK6 proprotein convertase subtilisin/kexin type 6
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PHF3 PHD finger protein 3
PML promyelocytic leukemia
PPFIBP2 PTPRF interacting protein, binding protein 2 (liprin beta 2)
PPP2CB protein phosphatase 2, catalytic subunit, beta isozyme
PPP2R2B protein phosphatase 2, regulatory subunit B, beta
PROZ protein Z, vitamin K-dependent plasma glycoprotein
RAD52 RAD52 homolog (S. cerevisiae)
RAG2 recombination activating gene 2
RECQL5 RecQ protein-like 5
S100A7 S100 calcium binding protein A7
SH3BP2 SH3-domain binding protein 2
SIGLEC15 sialic acid binding Ig-like lectin 15
SLC16A5 solute carrier family 16 (monocarboxylate transporter), member 5
SLC30A3 solute carrier family 30 (zinc transporter), member 3
SLC7A9 solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9
SLCO1A2 solute carrier organic anion transporter family, member 1A2
SPRY4 sprouty homolog 4 (Drosophila)
SRPR signal recognition particle receptor (docking protein)
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
SYT2 synaptotagmin II
TAAR5 trace amine associated receptor 5
TAPBP TAP binding protein (tapasin)
TMEM212 transmembrane protein 212
TRIO trio Rho guanine nucleotide exchange factor
VARS valyl-tRNA synthetase
VN1R1 vomeronasal 1 receptor 1
ZCCHC24 zinc finger, CCHC domain containing 24
ZNF471 zinc finger protein 471
ZNF639 zinc finger protein 639
ZNF750 zinc finger protein 750
ZNF76 zinc finger protein 76
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1

decreased expression

Symbol Name
ABCB8 ATP-binding cassette, sub-family B (MDR/TAP), member 8
ACTG2 actin, gamma 2, smooth muscle, enteric
AGMAT agmatine ureohydrolase (agmatinase)
ALPK1 alpha-kinase 1
ANP32A-IT1 ANP32A intronic transcript 1
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
BFSP1 beaded filament structural protein 1, filensin
BHLHB9 basic helix-loop-helix domain containing, class B, 9
C22ORF29 chromosome 22 open reading frame 29
C6ORF47 chromosome 6 open reading frame 47
CAPN15 calpain 15
CBX8 chromobox homolog 8
CCP110 centriolar coiled coil protein 110kDa
CD82 CD82 molecule
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11
CLCF1 cardiotrophin-like cytokine factor 1
CLGN calmegin
CORT cortistatin
CRYBB2P1 crystallin, beta B2 pseudogene 1
CTSF cathepsin F
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DBF4B DBF4 zinc finger B
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
DMTN dematin actin binding protein
DNAL4 dynein, axonemal, light chain 4
ELMO3 engulfment and cell motility 3
EPHX2 epoxide hydrolase 2, cytoplasmic
ETNK2 ethanolamine kinase 2
EXD3 exonuclease 3'-5' domain containing 3
EXO5 exonuclease 5
FAM212B family with sequence similarity 212, member B
FANCC Fanconi anemia, complementation group C
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GAMT guanidinoacetate N-methyltransferase
GLB1L galactosidase, beta 1-like
GPNMB glycoprotein (transmembrane) nmb
HIST1H1B histone cluster 1, H1b
HIST1H2AJ histone cluster 1, H2aj
HIST1H2AK histone cluster 1, H2ak
HIST1H2AL histone cluster 1, H2al
HMOX1 heme oxygenase 1
HYI hydroxypyruvate isomerase (putative)
IFI6 interferon, alpha-inducible protein 6
IFT81 intraflagellar transport 81
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
IP6K2 inositol hexakisphosphate kinase 2
KCNK12 potassium channel, two pore domain subfamily K, member 12
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KIAA0754 KIAA0754
LAMC3 laminin, gamma 3
LRRC37A3 leucine rich repeat containing 37, member A3
LYPLA2P1 lysophospholipase II pseudogene 1
LYRM9 LYR motif containing 9
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MPP6 membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)
MRPL41 mitochondrial ribosomal protein L41
MRPS18C mitochondrial ribosomal protein S18C
NCALD neurocalcin delta
NFE2L3 nuclear factor, erythroid 2-like 3
NOD1 nucleotide-binding oligomerization domain containing 1
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein
NT5DC3 5'-nucleotidase domain containing 3
PDE12 phosphodiesterase 12
PDE8B phosphodiesterase 8B
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
POMT2 protein-O-mannosyltransferase 2
PRKCE protein kinase C, epsilon
PRODH proline dehydrogenase (oxidase) 1
QPCTL glutaminyl-peptide cyclotransferase-like
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RFXAP regulatory factor X-associated protein
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
SETD1A SET domain containing 1A
SH2B3 SH2B adaptor protein 3
SIRT6 sirtuin 6
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae)
SLN sarcolipin
SMA4 glucuronidase, beta pseudogene
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STRA6 stimulated by retinoic acid 6
TBC1D17 TBC1 domain family, member 17
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TMEM45A transmembrane protein 45A
TSGA10 testis specific, 10
TTBK2 tau tubulin kinase 2
VIM vimentin
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
ZDHHC11 zinc finger, DHHC-type containing 11
ZFP30 ZFP30 zinc finger protein
ZNF141 zinc finger protein 141
ZNF611 zinc finger protein 611
ZNF696 zinc finger protein 696