Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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200 genes differentially expressed following the 15-delta prostaglandin J2-1011 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
ABHD4 | abhydrolase domain containing 4 |
ACVR1B | activin A receptor, type IB |
ADM | adrenomedullin |
AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) |
AKR1C1 | aldo-keto reductase family 1, member C1 |
AKR1C2 | aldo-keto reductase family 1, member C2 |
AKR1C3 | aldo-keto reductase family 1, member C3 |
AP1B1 | adaptor-related protein complex 1, beta 1 subunit |
ATF3 | activating transcription factor 3 |
BRF2 | BRF2, RNA polymerase III transcription initiation factor 50 kDa subunit |
CBR3 | carbonyl reductase 3 |
CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
CDKN2AIP | CDKN2A interacting protein |
CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
CREM | cAMP responsive element modulator |
CSRP2 | cysteine and glycine-rich protein 2 |
DDIT3 | DNA-damage-inducible transcript 3 |
DDIT4 | DNA-damage-inducible transcript 4 |
DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
DNAJB4 | DnaJ (Hsp40) homolog, subfamily B, member 4 |
DUSP1 | dual specificity phosphatase 1 |
DUSP5 | dual specificity phosphatase 5 |
ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 |
ETV5 | ets variant 5 |
F3 | coagulation factor III (thromboplastin, tissue factor) |
FAM129A | family with sequence similarity 129, member A |
FAM49B | family with sequence similarity 49, member B |
FAS | Fas cell surface death receptor |
FOSL1 | FOS-like antigen 1 |
FYN | FYN proto-oncogene, Src family tyrosine kinase |
GADD45A | growth arrest and DNA-damage-inducible, alpha |
GADD45G | growth arrest and DNA-damage-inducible, gamma |
GCLM | glutamate-cysteine ligase, modifier subunit |
GEM | GTP binding protein overexpressed in skeletal muscle |
GPX2 | glutathione peroxidase 2 |
GPX3 | glutathione peroxidase 3 |
GRB10 | growth factor receptor-bound protein 10 |
HIST1H2BJ | histone cluster 1, H2bj |
HMOX1 | heme oxygenase 1 |
HSPA12A | heat shock 70kDa protein 12A |
HSPA1A | heat shock 70kDa protein 1A |
HSPA1L | heat shock 70kDa protein 1-like |
HSPA4L | heat shock 70kDa protein 4-like |
HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
HSPH1 | heat shock 105kDa/110kDa protein 1 |
IER5 | immediate early response 5 |
IFRD1 | interferon-related developmental regulator 1 |
IL15RA | interleukin 15 receptor, alpha |
INHBE | inhibin, beta E |
IQCG | IQ motif containing G |
JUN | jun proto-oncogene |
KLF6 | Kruppel-like factor 6 |
KLHL24 | kelch-like family member 24 |
LARP6 | La ribonucleoprotein domain family, member 6 |
LDLR | low density lipoprotein receptor |
LGALS8 | lectin, galactoside-binding, soluble, 8 |
LPIN1 | lipin 1 |
LRP5L | low density lipoprotein receptor-related protein 5-like |
MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
MAP1B | microtubule-associated protein 1B |
MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase |
ME1 | malic enzyme 1, NADP(+)-dependent, cytosolic |
MINOS1P1 | mitochondrial inner membrane organizing system 1 pseudogene 1 |
MIR22HG | MIR22 host gene |
MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 |
MSX1 | msh homeobox 1 |
NBL1 | neuroblastoma 1, DAN family BMP antagonist |
NDRG1 | N-myc downstream regulated 1 |
NFIL3 | nuclear factor, interleukin 3 regulated |
OSGIN1 | oxidative stress induced growth inhibitor 1 |
P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II |
PCYT1A | phosphate cytidylyltransferase 1, choline, alpha |
PIK3CD | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta |
PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 |
PPARD | peroxisome proliferator-activated receptor delta |
PPP1R15A | protein phosphatase 1, regulatory subunit 15A |
RCN1 | reticulocalbin 1, EF-hand calcium binding domain |
RGCC | regulator of cell cycle |
SEL1L3 | sel-1 suppressor of lin-12-like 3 (C. elegans) |
SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) |
SH3BGR | SH3 domain binding glutamate-rich protein |
SLC1A4 | solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 |
SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 |
STYK1 | serine/threonine/tyrosine kinase 1 |
TES | testin LIM domain protein |
TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b |
TNFSF9 | tumor necrosis factor (ligand) superfamily, member 9 |
TPP1 | tripeptidyl peptidase I |
TRIB3 | tribbles pseudokinase 3 |
TRIM2 | tripartite motif containing 2 |
TUBA4A | tubulin, alpha 4a |
UBB | ubiquitin B |
ULBP2 | UL16 binding protein 2 |
UPP1 | uridine phosphorylase 1 |
VEGFA | vascular endothelial growth factor A |
ZDHHC11 | zinc finger, DHHC-type containing 11 |
ZNF350 | zinc finger protein 350 |
ZNF365 | zinc finger protein 365 |
ZNF473 | zinc finger protein 473 |
Symbol | Name |
---|---|
ANP32A-IT1 | ANP32A intronic transcript 1 |
ARID5B | AT rich interactive domain 5B (MRF1-like) |
ARMCX1 | armadillo repeat containing, X-linked 1 |
B3GNT1 | |
BAMBI | BMP and activin membrane-bound inhibitor |
BATF | basic leucine zipper transcription factor, ATF-like |
BCL11B | B-cell CLL/lymphoma 11B (zinc finger protein) |
BRINP3 | bone morphogenetic protein/retinoic acid inducible neural-specific 3 |
BRIP1 | BRCA1 interacting protein C-terminal helicase 1 |
C11ORF68 | chromosome 11 open reading frame 68 |
C9ORF40 | chromosome 9 open reading frame 40 |
CBFA2T3 | core-binding factor, runt domain, alpha subunit 2; translocated to, 3 |
CCNE2 | cyclin E2 |
CCNF | cyclin F |
CCNO | cyclin O |
CENPC | centromere protein C |
CLDN9 | claudin 9 |
CRY2 | cryptochrome circadian clock 2 |
CTDSP1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 |
CXCL12 | chemokine (C-X-C motif) ligand 12 |
CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
CYP26A1 | cytochrome P450, family 26, subfamily A, polypeptide 1 |
DEAF1 | DEAF1 transcription factor |
DHRS11 | dehydrogenase/reductase (SDR family) member 11 |
DKK1 | dickkopf WNT signaling pathway inhibitor 1 |
DSN1 | DSN1, MIS12 kinetochore complex component |
DTL | denticleless E3 ubiquitin protein ligase homolog (Drosophila) |
E2F8 | E2F transcription factor 8 |
EFNA1 | ephrin-A1 |
EGR3 | early growth response 3 |
ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) |
EPHA4 | EPH receptor A4 |
EPN3 | epsin 3 |
ERCC6L | excision repair cross-complementation group 6-like |
FBXO5 | F-box protein 5 |
FEN1 | flap structure-specific endonuclease 1 |
GALK1 | galactokinase 1 |
GCNT1 | glucosaminyl (N-acetyl) transferase 1, core 2 |
GJA1 | gap junction protein, alpha 1, 43kDa |
GPR19 | G protein-coupled receptor 19 |
H2AFJ | H2A histone family, member J |
HEY2 | hes-related family bHLH transcription factor with YRPW motif 2 |
HLA-DRB1 | major histocompatibility complex, class II, DR beta 1 |
HYAL2 | hyaluronoglucosaminidase 2 |
IMP3 | IMP3, U3 small nucleolar ribonucleoprotein |
KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 |
LINC00339 | long intergenic non-protein coding RNA 339 |
LY6G5C | lymphocyte antigen 6 complex, locus G5C |
MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B |
MAP1S | microtubule-associated protein 1S |
MCM10 | minichromosome maintenance complex component 10 |
MEIS1 | Meis homeobox 1 |
MEIS2 | Meis homeobox 2 |
METTL16 | methyltransferase like 16 |
MOGS | mannosyl-oligosaccharide glucosidase |
MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 |
NPY1R | neuropeptide Y receptor Y1 |
NPY5R | neuropeptide Y receptor Y5 |
NR2F2 | nuclear receptor subfamily 2, group F, member 2 |
OPN3 | opsin 3 |
P2RY2 | purinergic receptor P2Y, G-protein coupled, 2 |
PAQR4 | progestin and adipoQ receptor family member IV |
PCNXL4 | pecanex-like 4 (Drosophila) |
PEX11A | peroxisomal biogenesis factor 11 alpha |
PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) |
PIK3R2 | phosphoinositide-3-kinase, regulatory subunit 2 (beta) |
PODXL2 | podocalyxin-like 2 |
PP14571 | uncharacterized LOC100130449 |
PPP1R3C | protein phosphatase 1, regulatory subunit 3C |
PRKCD | protein kinase C, delta |
PRMT7 | protein arginine methyltransferase 7 |
PRR15L | proline rich 15-like |
PSRC1 | proline/serine-rich coiled-coil 1 |
PTTG3P | pituitary tumor-transforming 3, pseudogene |
PYCRL | pyrroline-5-carboxylate reductase-like |
RAB26 | RAB26, member RAS oncogene family |
RAD54L | RAD54-like (S. cerevisiae) |
RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 |
RAPGEFL1 | Rap guanine nucleotide exchange factor (GEF)-like 1 |
RGS16 | regulator of G-protein signaling 16 |
RHPN1-AS1 | RHPN1 antisense RNA 1 (head to head) |
RLN2 | relaxin 2 |
RWDD2A | RWD domain containing 2A |
SCUBE2 | signal peptide, CUB domain, EGF-like 2 |
SEMA4C | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C |
SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 |
SNHG3 | small nucleolar RNA host gene 3 |
SULF1 | sulfatase 1 |
SYTL2 | synaptotagmin-like 2 |
TCEAL1 | transcription elongation factor A (SII)-like 1 |
TCTN2 | tectonic family member 2 |
TEAD3 | TEA domain family member 3 |
TGFB3 | transforming growth factor, beta 3 |
TMEM164 | transmembrane protein 164 |
TOE1 | target of EGR1, member 1 (nuclear) |
TRAPPC11 | trafficking protein particle complex 11 |
UBTF | upstream binding transcription factor, RNA polymerase I |
ZMYM3 | zinc finger, MYM-type 3 |
ZNF276 | zinc finger protein 276 |
ZNF767P | zinc finger family member 767, pseudogene |