Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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199 genes differentially expressed following the 15-delta prostaglandin J2-1656 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
ABHD3 | abhydrolase domain containing 3 |
ABHD4 | abhydrolase domain containing 4 |
ADM | adrenomedullin |
ADPRM | ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent |
AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) |
AKR1C1 | aldo-keto reductase family 1, member C1 |
AKR1C2 | aldo-keto reductase family 1, member C2 |
AKR1C3 | aldo-keto reductase family 1, member C3 |
ANKRD11 | ankyrin repeat domain 11 |
AP1S1 | adaptor-related protein complex 1, sigma 1 subunit |
APOBEC3A | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A |
ASF1A | anti-silencing function 1A histone chaperone |
ASNS | asparagine synthetase (glutamine-hydrolyzing) |
ATF3 | activating transcription factor 3 |
BAX | BCL2-associated X protein |
BIN1 | bridging integrator 1 |
C2ORF27A | chromosome 2 open reading frame 27A |
CBR3 | carbonyl reductase 3 |
CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
CREM | cAMP responsive element modulator |
CSRP2 | cysteine and glycine-rich protein 2 |
CTH | cystathionine gamma-lyase |
CYP4F11 | cytochrome P450, family 4, subfamily F, polypeptide 11 |
DDIT3 | DNA-damage-inducible transcript 3 |
DDIT4 | DNA-damage-inducible transcript 4 |
DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) |
DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
DNAJB4 | DnaJ (Hsp40) homolog, subfamily B, member 4 |
DUSP1 | dual specificity phosphatase 1 |
EML2 | echinoderm microtubule associated protein like 2 |
ERMAP | erythroblast membrane-associated protein (Scianna blood group) |
ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 |
F3 | coagulation factor III (thromboplastin, tissue factor) |
FAS | Fas cell surface death receptor |
FOSL1 | FOS-like antigen 1 |
FYN | FYN proto-oncogene, Src family tyrosine kinase |
GADD45A | growth arrest and DNA-damage-inducible, alpha |
GCLC | glutamate-cysteine ligase, catalytic subunit |
GCLM | glutamate-cysteine ligase, modifier subunit |
GPX3 | glutathione peroxidase 3 |
GRB10 | growth factor receptor-bound protein 10 |
HIRA | histone cell cycle regulator |
HLA-G | major histocompatibility complex, class I, G |
HMHA1 | histocompatibility (minor) HA-1 |
HMOX1 | heme oxygenase 1 |
HOMER3 | homer scaffolding protein 3 |
HSPA1A | heat shock 70kDa protein 1A |
HSPA1L | heat shock 70kDa protein 1-like |
HSPA4L | heat shock 70kDa protein 4-like |
HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
HSPH1 | heat shock 105kDa/110kDa protein 1 |
IFRD1 | interferon-related developmental regulator 1 |
INHBE | inhibin, beta E |
JUN | jun proto-oncogene |
LARP6 | La ribonucleoprotein domain family, member 6 |
LDLR | low density lipoprotein receptor |
LGALS8 | lectin, galactoside-binding, soluble, 8 |
MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
MAFG | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G |
MAP1B | microtubule-associated protein 1B |
ME1 | malic enzyme 1, NADP(+)-dependent, cytosolic |
MIR22HG | MIR22 host gene |
MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 |
NAP1L2 | nucleosome assembly protein 1-like 2 |
NDRG1 | N-myc downstream regulated 1 |
OSGIN1 | oxidative stress induced growth inhibitor 1 |
P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II |
PCYT1A | phosphate cytidylyltransferase 1, choline, alpha |
PELO | pelota homolog (Drosophila) |
PIM1 | Pim-1 proto-oncogene, serine/threonine kinase |
PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 |
PPP1R15A | protein phosphatase 1, regulatory subunit 15A |
PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha |
RGCC | regulator of cell cycle |
RIT1 | Ras-like without CAAX 1 |
RPL7 | ribosomal protein L7 |
SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) |
SH3BGR | SH3 domain binding glutamate-rich protein |
SLC1A4 | solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 |
SLC48A1 | solute carrier family 48 (heme transporter), member 1 |
SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
SQSTM1 | sequestosome 1 |
STYK1 | serine/threonine/tyrosine kinase 1 |
TES | testin LIM domain protein |
TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b |
TNFSF9 | tumor necrosis factor (ligand) superfamily, member 9 |
TRIB3 | tribbles pseudokinase 3 |
TUBA4A | tubulin, alpha 4a |
TXNRD1 | thioredoxin reductase 1 |
UBB | ubiquitin B |
ULBP2 | UL16 binding protein 2 |
UNKL | unkempt family zinc finger-like |
VEGFA | vascular endothelial growth factor A |
VLDLR | very low density lipoprotein receptor |
ZNF227 | zinc finger protein 227 |
ZNF329 | zinc finger protein 329 |
ZNF350 | zinc finger protein 350 |
ZNF365 | zinc finger protein 365 |
Symbol | Name |
---|---|
ACKR3 | atypical chemokine receptor 3 |
AKAP12 | A kinase (PRKA) anchor protein 12 |
ANKRD36B | ankyrin repeat domain 36B |
ARMC6 | armadillo repeat containing 6 |
AURKB | aurora kinase B |
BAMBI | BMP and activin membrane-bound inhibitor |
BCL11B | B-cell CLL/lymphoma 11B (zinc finger protein) |
BCL2L2 | BCL2-like 2 |
BCOR | BCL6 corepressor |
BRINP3 | bone morphogenetic protein/retinoic acid inducible neural-specific 3 |
C11ORF68 | chromosome 11 open reading frame 68 |
C19ORF40 | chromosome 19 open reading frame 40 |
C6ORF47 | chromosome 6 open reading frame 47 |
CBFA2T3 | core-binding factor, runt domain, alpha subunit 2; translocated to, 3 |
CCNO | cyclin O |
CDC20 | cell division cycle 20 |
CLDN9 | claudin 9 |
CTDSP1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 |
CXCL12 | chemokine (C-X-C motif) ligand 12 |
CYP26A1 | cytochrome P450, family 26, subfamily A, polypeptide 1 |
DHRS11 | dehydrogenase/reductase (SDR family) member 11 |
DKK1 | dickkopf WNT signaling pathway inhibitor 1 |
DTL | denticleless E3 ubiquitin protein ligase homolog (Drosophila) |
E2F1 | E2F transcription factor 1 |
E2F8 | E2F transcription factor 8 |
EFNA1 | ephrin-A1 |
ELOVL4 | ELOVL fatty acid elongase 4 |
EVL | Enah/Vasp-like |
FAM111A | family with sequence similarity 111, member A |
FBXO5 | F-box protein 5 |
FKBP10 | FK506 binding protein 10, 65 kDa |
GALE | UDP-galactose-4-epimerase |
GHR | growth hormone receptor |
GJA1 | gap junction protein, alpha 1, 43kDa |
GTF2I | general transcription factor IIi |
H2AFJ | H2A histone family, member J |
HILPDA | hypoxia inducible lipid droplet-associated |
HIST1H2AJ | histone cluster 1, H2aj |
HSD17B8 | hydroxysteroid (17-beta) dehydrogenase 8 |
INF2 | inverted formin, FH2 and WH2 domain containing |
KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 |
KIAA0125 | KIAA0125 |
KIF18A | kinesin family member 18A |
KIF23 | kinesin family member 23 |
LRFN4 | leucine rich repeat and fibronectin type III domain containing 4 |
LRRC20 | leucine rich repeat containing 20 |
MAGEF1 | melanoma antigen family F1 |
MEIS1 | Meis homeobox 1 |
METTL8 | methyltransferase like 8 |
MOGS | mannosyl-oligosaccharide glucosidase |
MRM1 | mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) |
MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 |
NDE1 | nudE neurodevelopment protein 1 |
NPY1R | neuropeptide Y receptor Y1 |
NR2F2 | nuclear receptor subfamily 2, group F, member 2 |
NUP62CL | nucleoporin 62kDa C-terminal like |
OSGEPL1 | O-sialoglycoprotein endopeptidase-like 1 |
P2RY2 | purinergic receptor P2Y, G-protein coupled, 2 |
PAQR4 | progestin and adipoQ receptor family member IV |
PAQR6 | progestin and adipoQ receptor family member VI |
PARD6A | par-6 family cell polarity regulator alpha |
PDZK1 | PDZ domain containing 1 |
PKIA | protein kinase (cAMP-dependent, catalytic) inhibitor alpha |
POLD1 | polymerase (DNA directed), delta 1, catalytic subunit |
POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit |
PRKCD | protein kinase C, delta |
PRR15L | proline rich 15-like |
PSRC1 | proline/serine-rich coiled-coil 1 |
PTK6 | protein tyrosine kinase 6 |
PTPN18 | protein tyrosine phosphatase, non-receptor type 18 (brain-derived) |
PTPRU | protein tyrosine phosphatase, receptor type, U |
RAB5B | RAB5B, member RAS oncogene family |
RABL6 | RAB, member RAS oncogene family-like 6 |
RAPGEFL1 | Rap guanine nucleotide exchange factor (GEF)-like 1 |
RECQL4 | RecQ protein-like 4 |
RGS16 | regulator of G-protein signaling 16 |
RHOBTB1 | Rho-related BTB domain containing 1 |
RIPPLY3 | ripply transcriptional repressor 3 |
SALL2 | spalt-like transcription factor 2 |
SETD6 | SET domain containing 6 |
SHPK | sedoheptulokinase |
SLC2A10 | solute carrier family 2 (facilitated glucose transporter), member 10 |
SLC5A6 | solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 |
SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 |
SPC25 | SPC25, NDC80 kinetochore complex component |
SYTL2 | synaptotagmin-like 2 |
TCEAL1 | transcription elongation factor A (SII)-like 1 |
TGFB3 | transforming growth factor, beta 3 |
TMA16 | translation machinery associated 16 homolog (S. cerevisiae) |
TRIM45 | tripartite motif containing 45 |
TRPS1 | trichorhinophalangeal syndrome I |
UNC119 | unc-119 homolog (C. elegans) |
USP18 | ubiquitin specific peptidase 18 |
XYLT2 | xylosyltransferase II |
ZNF205 | zinc finger protein 205 |
ZNF250 | zinc finger protein 250 |
ZNF672 | zinc finger protein 672 |
ZNF816 | zinc finger protein 816 |
ZXDC | ZXD family zinc finger C |