Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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198 genes differentially expressed following the 15-delta prostaglandin J2-201 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
ACACA | acetyl-CoA carboxylase alpha |
ADAM22 | ADAM metallopeptidase domain 22 |
ADM2 | adrenomedullin 2 |
AGTR2 | angiotensin II receptor, type 2 |
AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) |
AKR1C1 | aldo-keto reductase family 1, member C1 |
AKR1C2 | aldo-keto reductase family 1, member C2 |
AKR1C3 | aldo-keto reductase family 1, member C3 |
AKT3 | v-akt murine thymoma viral oncogene homolog 3 |
ANKRD40 | ankyrin repeat domain 40 |
ANP32A | acidic (leucine-rich) nuclear phosphoprotein 32 family, member A |
API5 | apoptosis inhibitor 5 |
ARNT | aryl hydrocarbon receptor nuclear translocator |
ASAP3 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 |
ATF6 | activating transcription factor 6 |
BAIAP2 | BAI1-associated protein 2 |
BAZ2A | bromodomain adjacent to zinc finger domain, 2A |
BCL2L14 | BCL2-like 14 (apoptosis facilitator) |
C21ORF2 | chromosome 21 open reading frame 2 |
C2CD2L | C2CD2-like |
CADM3 | cell adhesion molecule 3 |
CD27 | CD27 molecule |
CEND1 | cell cycle exit and neuronal differentiation 1 |
CFAP70 | cilia and flagella associated protein 70 |
CLDN15 | claudin 15 |
CNTN1 | contactin 1 |
CORO1B | coronin, actin binding protein, 1B |
CRABP1 | cellular retinoic acid binding protein 1 |
CYP2A6 | cytochrome P450, family 2, subfamily A, polypeptide 6 |
DCN | decorin |
DHODH | dihydroorotate dehydrogenase (quinone) |
DRP2 | dystrophin related protein 2 |
ECM1 | extracellular matrix protein 1 |
EIF4EBP2 | eukaryotic translation initiation factor 4E binding protein 2 |
ERN2 | endoplasmic reticulum to nucleus signaling 2 |
FECH | ferrochelatase |
FLJ10038 | uncharacterized protein FLJ10038 |
FRMD8 | FERM domain containing 8 |
FXR2 | fragile X mental retardation, autosomal homolog 2 |
GCLC | glutamate-cysteine ligase, catalytic subunit |
GCLM | glutamate-cysteine ligase, modifier subunit |
HEG1 | heart development protein with EGF-like domains 1 |
HMOX1 | heme oxygenase 1 |
HNF1B | HNF1 homeobox B |
HS3ST2 | heparan sulfate (glucosamine) 3-O-sulfotransferase 2 |
HSPA12A | heat shock 70kDa protein 12A |
HTR6 | 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled |
IL11 | interleukin 11 |
IL15RA | interleukin 15 receptor, alpha |
ITIH2 | inter-alpha-trypsin inhibitor heavy chain 2 |
KCNS1 | potassium voltage-gated channel, modifier subfamily S, member 1 |
KRT6B | keratin 6B, type II |
LIG3 | ligase III, DNA, ATP-dependent |
LRP6 | low density lipoprotein receptor-related protein 6 |
ME1 | malic enzyme 1, NADP(+)-dependent, cytosolic |
NAP1L2 | nucleosome assembly protein 1-like 2 |
NCAM1 | neural cell adhesion molecule 1 |
OLFML2B | olfactomedin-like 2B |
OSGIN1 | oxidative stress induced growth inhibitor 1 |
PADI2 | peptidyl arginine deiminase, type II |
PLA2G12A | phospholipase A2, group XIIA |
PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 |
PRMT3 | protein arginine methyltransferase 3 |
PSAT1 | phosphoserine aminotransferase 1 |
PTGDS | prostaglandin D2 synthase 21kDa (brain) |
RAD51D | RAD51 paralog D |
RHO | rhodopsin |
RPS17P5 | ribosomal protein S17 pseudogene 5 |
RPUSD2 | RNA pseudouridylate synthase domain containing 2 |
S100A1 | S100 calcium binding protein A1 |
SH2D2A | SH2 domain containing 2A |
SHB | Src homology 2 domain containing adaptor protein B |
SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 |
SLC25A28 | solute carrier family 25 (mitochondrial iron transporter), member 28 |
SLC35D2 | solute carrier family 35 (UDP-GlcNAc/UDP-glucose transporter), member D2 |
SLC48A1 | solute carrier family 48 (heme transporter), member 1 |
SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 |
SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
STK38L | serine/threonine kinase 38 like |
SULT1B1 | sulfotransferase family, cytosolic, 1B, member 1 |
TAF1 | TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa |
TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 |
TCF7L1 | transcription factor 7-like 1 (T-cell specific, HMG-box) |
TIAM2 | T-cell lymphoma invasion and metastasis 2 |
TMBIM4 | transmembrane BAX inhibitor motif containing 4 |
TOM1 | target of myb1 (chicken) |
TSN | translin |
TXNRD1 | thioredoxin reductase 1 |
UBE3A | ubiquitin protein ligase E3A |
UNC93B1 | unc-93 homolog B1 (C. elegans) |
VPS13D | vacuolar protein sorting 13 homolog D (S. cerevisiae) |
WDTC1 | WD and tetratricopeptide repeats 1 |
ZFAND5 | zinc finger, AN1-type domain 5 |
ZNF142 | zinc finger protein 142 |
ZNF197 | zinc finger protein 197 |
ZNF287 | zinc finger protein 287 |
ZNF419 | zinc finger protein 419 |
ZSCAN32 | zinc finger and SCAN domain containing 32 |
Symbol | Name |
---|---|
ABLIM3 | actin binding LIM protein family, member 3 |
ACD | adrenocortical dysplasia homolog (mouse) |
ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 |
ALOX12P2 | arachidonate 12-lipoxygenase pseudogene 2 |
ARHGAP10 | Rho GTPase activating protein 10 |
ARRB2 | arrestin, beta 2 |
ASPA | aspartoacylase |
BEST2 | bestrophin 2 |
BHLHB9 | basic helix-loop-helix domain containing, class B, 9 |
BIK | BCL2-interacting killer (apoptosis-inducing) |
C11ORF80 | chromosome 11 open reading frame 80 |
C1QTNF9B-AS1 | C1QTNF9B antisense RNA 1 |
C5 | complement component 5 |
C5ORF45 | chromosome 5 open reading frame 45 |
CARS2 | cysteinyl-tRNA synthetase 2, mitochondrial (putative) |
CARTPT | CART prepropeptide |
CAV3 | caveolin 3 |
CCBL2 | cysteine conjugate-beta lyase 2 |
CCDC94 | coiled-coil domain containing 94 |
CHST12 | carbohydrate (chondroitin 4) sulfotransferase 12 |
CLCN1 | chloride channel, voltage-sensitive 1 |
CLDN11 | claudin 11 |
COBL | cordon-bleu WH2 repeat protein |
COLEC11 | collectin sub-family member 11 |
COLEC12 | collectin sub-family member 12 |
CRY1 | cryptochrome circadian clock 1 |
CRY2 | cryptochrome circadian clock 2 |
CTDNEP1 | CTD nuclear envelope phosphatase 1 |
DGCR5 | DiGeorge syndrome critical region gene 5 (non-protein coding) |
DIXDC1 | DIX domain containing 1 |
DLST | dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) |
DNA2 | DNA replication helicase/nuclease 2 |
DSG3 | desmoglein 3 |
EFNA3 | ephrin-A3 |
EMID1 | EMI domain containing 1 |
ERCC2 | excision repair cross-complementation group 2 |
FADS2 | fatty acid desaturase 2 |
FCHSD2 | FCH and double SH3 domains 2 |
FILIP1L | filamin A interacting protein 1-like |
GOLM1 | golgi membrane protein 1 |
GTF2H4 | general transcription factor IIH, polypeptide 4, 52kDa |
HEATR3 | HEAT repeat containing 3 |
HINFP | histone H4 transcription factor |
HIST1H1C | histone cluster 1, H1c |
IL7R | interleukin 7 receptor |
INSIG2 | insulin induced gene 2 |
JMJD4 | jumonji domain containing 4 |
KIF18A | kinesin family member 18A |
KIFC1 | kinesin family member C1 |
LGMN | legumain |
LIN7B | lin-7 homolog B (C. elegans) |
LMO1 | LIM domain only 1 (rhombotin 1) |
MGA | MGA, MAX dimerization protein |
MPPED1 | metallophosphoesterase domain containing 1 |
MPV17 | MpV17 mitochondrial inner membrane protein |
MUL1 | mitochondrial E3 ubiquitin protein ligase 1 |
NOD1 | nucleotide-binding oligomerization domain containing 1 |
NR1H3 | nuclear receptor subfamily 1, group H, member 3 |
NUBPL | nucleotide binding protein-like |
PAFAH1B2 | platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa) |
PARG | poly (ADP-ribose) glycohydrolase |
PDZD7 | PDZ domain containing 7 |
PELP1 | proline, glutamate and leucine rich protein 1 |
PEMT | phosphatidylethanolamine N-methyltransferase |
PHC1 | polyhomeotic homolog 1 (Drosophila) |
PHKA1 | phosphorylase kinase, alpha 1 (muscle) |
PIGH | phosphatidylinositol glycan anchor biosynthesis, class H |
PKD2L1 | polycystic kidney disease 2-like 1 |
PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) |
PLCD1 | phospholipase C, delta 1 |
PLEKHO1 | pleckstrin homology domain containing, family O member 1 |
PODNL1 | podocan-like 1 |
PSG11 | pregnancy specific beta-1-glycoprotein 11 |
RAB8B | RAB8B, member RAS oncogene family |
RAP1A | RAP1A, member of RAS oncogene family |
REM1 | RAS (RAD and GEM)-like GTP-binding 1 |
RND1 | Rho family GTPase 1 |
RORC | RAR-related orphan receptor C |
SETMAR | SET domain and mariner transposase fusion gene |
SLC27A5 | solute carrier family 27 (fatty acid transporter), member 5 |
SLC2A8 | solute carrier family 2 (facilitated glucose transporter), member 8 |
SSTR4 | somatostatin receptor 4 |
STK16 | serine/threonine kinase 16 |
SURF2 | surfeit 2 |
TAP1 | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) |
TCIRG1 | T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 |
TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) |
TFCP2L1 | transcription factor CP2-like 1 |
TGFBRAP1 | transforming growth factor, beta receptor associated protein 1 |
TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) |
TMEM104 | transmembrane protein 104 |
TMEM176A | transmembrane protein 176A |
TMSB4Y | thymosin beta 4, Y-linked |
VPS37B | vacuolar protein sorting 37 homolog B (S. cerevisiae) |
VWA1 | von Willebrand factor A domain containing 1 |
WDR62 | WD repeat domain 62 |
WWC2 | WW and C2 domain containing 2 |
XPNPEP3 | X-prolyl aminopeptidase 3, mitochondrial |
ZBED8 | zinc finger, BED-type containing 8 |
ZHX2 | zinc fingers and homeoboxes 2 |