15-delta prostaglandin J2-201 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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198 genes differentially expressed following the 15-delta prostaglandin J2-201 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACACA acetyl-CoA carboxylase alpha
ADAM22 ADAM metallopeptidase domain 22
ADM2 adrenomedullin 2
AGTR2 angiotensin II receptor, type 2
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
AKT3 v-akt murine thymoma viral oncogene homolog 3
ANKRD40 ankyrin repeat domain 40
ANP32A acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
API5 apoptosis inhibitor 5
ARNT aryl hydrocarbon receptor nuclear translocator
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
ATF6 activating transcription factor 6
BAIAP2 BAI1-associated protein 2
BAZ2A bromodomain adjacent to zinc finger domain, 2A
BCL2L14 BCL2-like 14 (apoptosis facilitator)
C21ORF2 chromosome 21 open reading frame 2
C2CD2L C2CD2-like
CADM3 cell adhesion molecule 3
CD27 CD27 molecule
CEND1 cell cycle exit and neuronal differentiation 1
CFAP70 cilia and flagella associated protein 70
CLDN15 claudin 15
CNTN1 contactin 1
CORO1B coronin, actin binding protein, 1B
CRABP1 cellular retinoic acid binding protein 1
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
DCN decorin
DHODH dihydroorotate dehydrogenase (quinone)
DRP2 dystrophin related protein 2
ECM1 extracellular matrix protein 1
EIF4EBP2 eukaryotic translation initiation factor 4E binding protein 2
ERN2 endoplasmic reticulum to nucleus signaling 2
FECH ferrochelatase
FLJ10038 uncharacterized protein FLJ10038
FRMD8 FERM domain containing 8
FXR2 fragile X mental retardation, autosomal homolog 2
GCLC glutamate-cysteine ligase, catalytic subunit
GCLM glutamate-cysteine ligase, modifier subunit
HEG1 heart development protein with EGF-like domains 1
HMOX1 heme oxygenase 1
HNF1B HNF1 homeobox B
HS3ST2 heparan sulfate (glucosamine) 3-O-sulfotransferase 2
HSPA12A heat shock 70kDa protein 12A
HTR6 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled
IL11 interleukin 11
IL15RA interleukin 15 receptor, alpha
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KRT6B keratin 6B, type II
LIG3 ligase III, DNA, ATP-dependent
LRP6 low density lipoprotein receptor-related protein 6
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
NAP1L2 nucleosome assembly protein 1-like 2
NCAM1 neural cell adhesion molecule 1
OLFML2B olfactomedin-like 2B
OSGIN1 oxidative stress induced growth inhibitor 1
PADI2 peptidyl arginine deiminase, type II
PLA2G12A phospholipase A2, group XIIA
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PRMT3 protein arginine methyltransferase 3
PSAT1 phosphoserine aminotransferase 1
PTGDS prostaglandin D2 synthase 21kDa (brain)
RAD51D RAD51 paralog D
RHO rhodopsin
RPS17P5 ribosomal protein S17 pseudogene 5
RPUSD2 RNA pseudouridylate synthase domain containing 2
S100A1 S100 calcium binding protein A1
SH2D2A SH2 domain containing 2A
SHB Src homology 2 domain containing adaptor protein B
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC25A28 solute carrier family 25 (mitochondrial iron transporter), member 28
SLC35D2 solute carrier family 35 (UDP-GlcNAc/UDP-glucose transporter), member D2
SLC48A1 solute carrier family 48 (heme transporter), member 1
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
STK38L serine/threonine kinase 38 like
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
TCF7L1 transcription factor 7-like 1 (T-cell specific, HMG-box)
TIAM2 T-cell lymphoma invasion and metastasis 2
TMBIM4 transmembrane BAX inhibitor motif containing 4
TOM1 target of myb1 (chicken)
TSN translin
TXNRD1 thioredoxin reductase 1
UBE3A ubiquitin protein ligase E3A
UNC93B1 unc-93 homolog B1 (C. elegans)
VPS13D vacuolar protein sorting 13 homolog D (S. cerevisiae)
WDTC1 WD and tetratricopeptide repeats 1
ZFAND5 zinc finger, AN1-type domain 5
ZNF142 zinc finger protein 142
ZNF197 zinc finger protein 197
ZNF287 zinc finger protein 287
ZNF419 zinc finger protein 419
ZSCAN32 zinc finger and SCAN domain containing 32

decreased expression

Symbol Name
ABLIM3 actin binding LIM protein family, member 3
ACD adrenocortical dysplasia homolog (mouse)
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
ALOX12P2 arachidonate 12-lipoxygenase pseudogene 2
ARHGAP10 Rho GTPase activating protein 10
ARRB2 arrestin, beta 2
ASPA aspartoacylase
BEST2 bestrophin 2
BHLHB9 basic helix-loop-helix domain containing, class B, 9
BIK BCL2-interacting killer (apoptosis-inducing)
C11ORF80 chromosome 11 open reading frame 80
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
C5 complement component 5
C5ORF45 chromosome 5 open reading frame 45
CARS2 cysteinyl-tRNA synthetase 2, mitochondrial (putative)
CARTPT CART prepropeptide
CAV3 caveolin 3
CCBL2 cysteine conjugate-beta lyase 2
CCDC94 coiled-coil domain containing 94
CHST12 carbohydrate (chondroitin 4) sulfotransferase 12
CLCN1 chloride channel, voltage-sensitive 1
CLDN11 claudin 11
COBL cordon-bleu WH2 repeat protein
COLEC11 collectin sub-family member 11
COLEC12 collectin sub-family member 12
CRY1 cryptochrome circadian clock 1
CRY2 cryptochrome circadian clock 2
CTDNEP1 CTD nuclear envelope phosphatase 1
DGCR5 DiGeorge syndrome critical region gene 5 (non-protein coding)
DIXDC1 DIX domain containing 1
DLST dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)
DNA2 DNA replication helicase/nuclease 2
DSG3 desmoglein 3
EFNA3 ephrin-A3
EMID1 EMI domain containing 1
ERCC2 excision repair cross-complementation group 2
FADS2 fatty acid desaturase 2
FCHSD2 FCH and double SH3 domains 2
FILIP1L filamin A interacting protein 1-like
GOLM1 golgi membrane protein 1
GTF2H4 general transcription factor IIH, polypeptide 4, 52kDa
HEATR3 HEAT repeat containing 3
HINFP histone H4 transcription factor
HIST1H1C histone cluster 1, H1c
IL7R interleukin 7 receptor
INSIG2 insulin induced gene 2
JMJD4 jumonji domain containing 4
KIF18A kinesin family member 18A
KIFC1 kinesin family member C1
LGMN legumain
LIN7B lin-7 homolog B (C. elegans)
LMO1 LIM domain only 1 (rhombotin 1)
MGA MGA, MAX dimerization protein
MPPED1 metallophosphoesterase domain containing 1
MPV17 MpV17 mitochondrial inner membrane protein
MUL1 mitochondrial E3 ubiquitin protein ligase 1
NOD1 nucleotide-binding oligomerization domain containing 1
NR1H3 nuclear receptor subfamily 1, group H, member 3
NUBPL nucleotide binding protein-like
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)
PARG poly (ADP-ribose) glycohydrolase
PDZD7 PDZ domain containing 7
PELP1 proline, glutamate and leucine rich protein 1
PEMT phosphatidylethanolamine N-methyltransferase
PHC1 polyhomeotic homolog 1 (Drosophila)
PHKA1 phosphorylase kinase, alpha 1 (muscle)
PIGH phosphatidylinositol glycan anchor biosynthesis, class H
PKD2L1 polycystic kidney disease 2-like 1
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PLCD1 phospholipase C, delta 1
PLEKHO1 pleckstrin homology domain containing, family O member 1
PODNL1 podocan-like 1
PSG11 pregnancy specific beta-1-glycoprotein 11
RAB8B RAB8B, member RAS oncogene family
RAP1A RAP1A, member of RAS oncogene family
REM1 RAS (RAD and GEM)-like GTP-binding 1
RND1 Rho family GTPase 1
RORC RAR-related orphan receptor C
SETMAR SET domain and mariner transposase fusion gene
SLC27A5 solute carrier family 27 (fatty acid transporter), member 5
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8
SSTR4 somatostatin receptor 4
STK16 serine/threonine kinase 16
SURF2 surfeit 2
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TCIRG1 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TFCP2L1 transcription factor CP2-like 1
TGFBRAP1 transforming growth factor, beta receptor associated protein 1
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast)
TMEM104 transmembrane protein 104
TMEM176A transmembrane protein 176A
TMSB4Y thymosin beta 4, Y-linked
VPS37B vacuolar protein sorting 37 homolog B (S. cerevisiae)
VWA1 von Willebrand factor A domain containing 1
WDR62 WD repeat domain 62
WWC2 WW and C2 domain containing 2
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial
ZBED8 zinc finger, BED-type containing 8
ZHX2 zinc fingers and homeoboxes 2