Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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199 genes differentially expressed following the 15-delta prostaglandin J2-4455 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase |
ACTN2 | actinin, alpha 2 |
ADM | adrenomedullin |
ADRB2 | adrenoceptor beta 2, surface |
AEN | apoptosis enhancing nuclease |
AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) |
AKR1C1 | aldo-keto reductase family 1, member C1 |
AKR1C2 | aldo-keto reductase family 1, member C2 |
AKR1C3 | aldo-keto reductase family 1, member C3 |
AMIGO2 | adhesion molecule with Ig-like domain 2 |
ANGPTL2 | angiopoietin-like 2 |
ANGPTL4 | angiopoietin-like 4 |
ATF3 | activating transcription factor 3 |
BTF3P11 | basic transcription factor 3 pseudogene 11 |
CCNK | cyclin K |
CD52 | CD52 molecule |
CD53 | CD53 molecule |
CDH7 | cadherin 7, type 2 |
CDHR2 | cadherin-related family member 2 |
CETP | cholesteryl ester transfer protein, plasma |
CNPY4 | canopy FGF signaling regulator 4 |
CRYAB | crystallin, alpha B |
CXCL3 | chemokine (C-X-C motif) ligand 3 |
CYP2C9 | cytochrome P450, family 2, subfamily C, polypeptide 9 |
DCAF13 | DDB1 and CUL4 associated factor 13 |
DDR1-AS1 | DDR1 antisense RNA 1 (head to head) |
DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked |
DKFZP434C153 | DKFZP434C153 protein |
DNAJB4 | DnaJ (Hsp40) homolog, subfamily B, member 4 |
DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 |
DUSP1 | dual specificity phosphatase 1 |
EDRF1 | erythroid differentiation regulatory factor 1 |
ELOVL4 | ELOVL fatty acid elongase 4 |
FABP4 | fatty acid binding protein 4, adipocyte |
FBXL18 | F-box and leucine-rich repeat protein 18 |
FGF1 | fibroblast growth factor 1 (acidic) |
FUT5 | fucosyltransferase 5 (alpha (1,3) fucosyltransferase) |
GABARAPL1 | GABA(A) receptor-associated protein like 1 |
GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type |
HMOX1 | heme oxygenase 1 |
HSPA12A | heat shock 70kDa protein 12A |
HSPA1A | heat shock 70kDa protein 1A |
HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
HSPB8 | heat shock 22kDa protein 8 |
HSPH1 | heat shock 105kDa/110kDa protein 1 |
IRS2 | insulin receptor substrate 2 |
ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) |
ITGA7 | integrin, alpha 7 |
JUN | jun proto-oncogene |
KAZN | kazrin, periplakin interacting protein |
KCNH2 | potassium channel, voltage gated eag related subfamily H, member 2 |
KIF25-AS1 | KIF25 antisense RNA 1 |
KIF5C | kinesin family member 5C |
KLHL22 | kelch-like family member 22 |
LAMA4 | laminin, alpha 4 |
LDHC | lactate dehydrogenase C |
LMTK2 | lemur tyrosine kinase 2 |
LOC202181 | SUMO-interacting motifs containing 1 pseudogene |
LPIN1 | lipin 1 |
LYPD3 | LY6/PLAUR domain containing 3 |
NBR2 | neighbor of BRCA1 gene 2 (non-protein coding) |
NCF4 | neutrophil cytosolic factor 4, 40kDa |
NDUFA2 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa |
NF1 | neurofibromin 1 |
OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa |
OSGIN1 | oxidative stress induced growth inhibitor 1 |
PAPOLA | poly(A) polymerase alpha |
PDE4DIP | phosphodiesterase 4D interacting protein |
PIM1 | Pim-1 proto-oncogene, serine/threonine kinase |
PLIN2 | perilipin 2 |
PLP1 | proteolipid protein 1 |
PTGER3 | prostaglandin E receptor 3 (subtype EP3) |
PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 |
RAB6A | RAB6A, member RAS oncogene family |
RAVER2 | ribonucleoprotein, PTB-binding 2 |
REPS1 | RALBP1 associated Eps domain containing 1 |
RGCC | regulator of cell cycle |
RHOB | ras homolog family member B |
RND1 | Rho family GTPase 1 |
RUNDC3A | RUN domain containing 3A |
SLC48A1 | solute carrier family 48 (heme transporter), member 1 |
SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 |
SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
SMAD6 | SMAD family member 6 |
SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
SOCS7 | suppressor of cytokine signaling 7 |
SORBS1 | sorbin and SH3 domain containing 1 |
SPRR2B | small proline-rich protein 2B |
SQSTM1 | sequestosome 1 |
STK17B | serine/threonine kinase 17b |
TAF7L | TAF7-like RNA polymerase II, TATA box binding protein (TBP)-associated factor, 50kDa |
TGM4 | transglutaminase 4 |
TMEM74B | transmembrane protein 74B |
TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b |
TPM3 | tropomyosin 3 |
UNKL | unkempt family zinc finger-like |
WDR1 | WD repeat domain 1 |
WRNIP1 | Werner helicase interacting protein 1 |
ZNF516 | zinc finger protein 516 |
Symbol | Name |
---|---|
ACBD4 | acyl-CoA binding domain containing 4 |
ADGRB2 | adhesion G protein-coupled receptor B2 |
AFAP1 | actin filament associated protein 1 |
ALPK1 | alpha-kinase 1 |
ARHGEF10L | Rho guanine nucleotide exchange factor (GEF) 10-like |
ARMCX2 | armadillo repeat containing, X-linked 2 |
ARSB | arylsulfatase B |
ATAD5 | ATPase family, AAA domain containing 5 |
B3GALT4 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4 |
BFSP1 | beaded filament structural protein 1, filensin |
BHLHE40 | basic helix-loop-helix family, member e40 |
C1QTNF3 | C1q and tumor necrosis factor related protein 3 |
C6ORF47 | chromosome 6 open reading frame 47 |
CCDC85C | coiled-coil domain containing 85C |
CCNJL | cyclin J-like |
CCP110 | centriolar coiled coil protein 110kDa |
CDKN2D | cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) |
CLDN11 | claudin 11 |
CSRNP3 | cysteine-serine-rich nuclear protein 3 |
CTDP1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 |
CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) |
DDN | dendrin |
DNAH7 | dynein, axonemal, heavy chain 7 |
DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 |
FAM131B | family with sequence similarity 131, member B |
FZD8 | frizzled class receptor 8 |
GIT1 | G protein-coupled receptor kinase interacting ArfGAP 1 |
GNA14 | guanine nucleotide binding protein (G protein), alpha 14 |
GPRIN2 | G protein regulated inducer of neurite outgrowth 2 |
GRPR | gastrin-releasing peptide receptor |
GTF2A1 | general transcription factor IIA, 1, 19/37kDa |
GTF2I | general transcription factor IIi |
H1F0 | H1 histone family, member 0 |
IFI6 | interferon, alpha-inducible protein 6 |
IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 |
IGFLR1 | IGF-like family receptor 1 |
IL12RB1 | interleukin 12 receptor, beta 1 |
IL1RAPL2 | interleukin 1 receptor accessory protein-like 2 |
IL33 | interleukin 33 |
INCENP | inner centromere protein antigens 135/155kDa |
INPP5J | inositol polyphosphate-5-phosphatase J |
INPPL1 | inositol polyphosphate phosphatase-like 1 |
ITGB2 | integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) |
JAK2 | Janus kinase 2 |
KCTD15 | potassium channel tetramerization domain containing 15 |
KLHL29 | kelch-like family member 29 |
LHPP | phospholysine phosphohistidine inorganic pyrophosphate phosphatase |
LMNB1 | lamin B1 |
LMO7 | LIM domain 7 |
LOC730101 | uncharacterized LOC730101 |
MDFI | MyoD family inhibitor |
MVD | mevalonate (diphospho) decarboxylase |
NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta |
NPY1R | neuropeptide Y receptor Y1 |
NR3C2 | nuclear receptor subfamily 3, group C, member 2 |
ODF2 | outer dense fiber of sperm tails 2 |
PADI1 | peptidyl arginine deiminase, type I |
PAIP2B | poly(A) binding protein interacting protein 2B |
PALMD | palmdelphin |
PAQR6 | progestin and adipoQ receptor family member VI |
PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 |
PLAT | plasminogen activator, tissue |
PLD2 | phospholipase D2 |
PLSCR2 | phospholipid scramblase 2 |
POLM | polymerase (DNA directed), mu |
POU3F2 | POU class 3 homeobox 2 |
PQLC2 | PQ loop repeat containing 2 |
PRKG2 | protein kinase, cGMP-dependent, type II |
PRR15L | proline rich 15-like |
PSMB9 | proteasome (prosome, macropain) subunit, beta type, 9 |
RAC3 | ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) |
RGS2 | regulator of G-protein signaling 2 |
RNF122 | ring finger protein 122 |
RNF43 | ring finger protein 43 |
SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A |
SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
SERPINB3 | serpin peptidase inhibitor, clade B (ovalbumin), member 3 |
SETD1A | SET domain containing 1A |
SIRT6 | sirtuin 6 |
SLC22A14 | solute carrier family 22, member 14 |
SMA4 | glucuronidase, beta pseudogene |
SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) |
SPTBN2 | spectrin, beta, non-erythrocytic 2 |
ST5 | suppression of tumorigenicity 5 |
TAB1 | TGF-beta activated kinase 1/MAP3K7 binding protein 1 |
TAGLN | transgelin |
TAGLN3 | transgelin 3 |
TCEAL2 | transcription elongation factor A (SII)-like 2 |
TLR1 | toll-like receptor 1 |
TMEM19 | transmembrane protein 19 |
TNS2 | tensin 2 |
TRAIP | TRAF interacting protein |
UNC93B1 | unc-93 homolog B1 (C. elegans) |
VEGFB | vascular endothelial growth factor B |
VGF | VGF nerve growth factor inducible |
WNT16 | wingless-type MMTV integration site family, member 16 |
ZNF428 | zinc finger protein 428 |
ZNF446 | zinc finger protein 446 |