15-delta prostaglandin J2-564 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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196 genes differentially expressed following the 15-delta prostaglandin J2-564 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACBD3 acyl-CoA binding domain containing 3
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
ADAP1 ArfGAP with dual PH domains 1
ATM ATM serine/threonine kinase
AURKB aurora kinase B
CA1 carbonic anhydrase I
CACFD1 calcium channel flower domain containing 1
CASP4 caspase 4, apoptosis-related cysteine peptidase
CCNJL cyclin J-like
CD22 CD22 molecule
CD2BP2 CD2 (cytoplasmic tail) binding protein 2
CD79A CD79a molecule, immunoglobulin-associated alpha
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
COL1A1 collagen, type I, alpha 1
CRK v-crk avian sarcoma virus CT10 oncogene homolog
DAXX death-domain associated protein
DHFR dihydrofolate reductase
DHRS9 dehydrogenase/reductase (SDR family) member 9
DLGAP4 discs, large (Drosophila) homolog-associated protein 4
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DRG2 developmentally regulated GTP binding protein 2
DYSF dysferlin
EGFR epidermal growth factor receptor
EMD emerin
ERN2 endoplasmic reticulum to nucleus signaling 2
FAM168A family with sequence similarity 168, member A
FKBP8 FK506 binding protein 8, 38kDa
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
FXR2 fragile X mental retardation, autosomal homolog 2
GCLM glutamate-cysteine ligase, modifier subunit
GNS glucosamine (N-acetyl)-6-sulfatase
GPRIN2 G protein regulated inducer of neurite outgrowth 2
HECW1 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
HMOX1 heme oxygenase 1
HNRNPA3 heterogeneous nuclear ribonucleoprotein A3
HNRNPUL2 heterogeneous nuclear ribonucleoprotein U-like 2
ICAM1 intercellular adhesion molecule 1
IDH3G isocitrate dehydrogenase 3 (NAD+) gamma
IFT46 intraflagellar transport 46
IL27RA interleukin 27 receptor, alpha
JADE1 jade family PHD finger 1
KDM2A lysine (K)-specific demethylase 2A
KLHDC3 kelch domain containing 3
KPNA4 karyopherin alpha 4 (importin alpha 3)
LGALS8 lectin, galactoside-binding, soluble, 8
LIF leukemia inhibitory factor
LMNA lamin A/C
MASP2 mannan-binding lectin serine peptidase 2
MBOAT7 membrane bound O-acyltransferase domain containing 7
MMP17 matrix metallopeptidase 17 (membrane-inserted)
MT1E metallothionein 1E
MTPAP mitochondrial poly(A) polymerase
MYO15B myosin XVB
NDE1 nudE neurodevelopment protein 1
OGDHL oxoglutarate dehydrogenase-like
OGFR opioid growth factor receptor
PATZ1 POZ (BTB) and AT hook containing zinc finger 1
PCDHGB5 protocadherin gamma subfamily B, 5
PHLDB1 pleckstrin homology-like domain, family B, member 1
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PLCG1 phospholipase C, gamma 1
PLD2 phospholipase D2
PNPLA6 patatin-like phospholipase domain containing 6
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PTP4A3 protein tyrosine phosphatase type IVA, member 3
RAB3GAP2 RAB3 GTPase activating protein subunit 2 (non-catalytic)
RAMP3 receptor (G protein-coupled) activity modifying protein 3
RANBP3 RAN binding protein 3
RBM12B RNA binding motif protein 12B
RBM15B RNA binding motif protein 15B
RMND5B required for meiotic nuclear division 5 homolog B (S. cerevisiae)
RPLP2 ribosomal protein, large, P2
SEC24C SEC24 family member C
SERP1 stress-associated endoplasmic reticulum protein 1
SGSM2 small G protein signaling modulator 2
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SNW1 SNW domain containing 1
SPDEF SAM pointed domain containing ETS transcription factor
SRPK2 SRSF protein kinase 2
STX1A syntaxin 1A (brain)
TAGLN2 transgelin 2
TBC1D4 TBC1 domain family, member 4
TMEM134 transmembrane protein 134
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TRIM16 tripartite motif containing 16
TRMT61A tRNA methyltransferase 61A
TRRAP transformation/transcription domain-associated protein
UIMC1 ubiquitin interaction motif containing 1
WDTC1 WD and tetratricopeptide repeats 1
XPC xeroderma pigmentosum, complementation group C
ZDHHC18 zinc finger, DHHC-type containing 18
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZMYM4 zinc finger, MYM-type 4
ZNF277 zinc finger protein 277
ZNF43 zinc finger protein 43
ZNF747 zinc finger protein 747

decreased expression

Symbol Name
AATK apoptosis-associated tyrosine kinase
ANKRD49 ankyrin repeat domain 49
ARL4A ADP-ribosylation factor-like 4A
ATPIF1 ATPase inhibitory factor 1
BCL7C B-cell CLL/lymphoma 7C
BEX1 brain expressed, X-linked 1
C1QTNF1 C1q and tumor necrosis factor related protein 1
CA14 carbonic anhydrase XIV
CBY1 chibby homolog 1 (Drosophila)
CCNL1 cyclin L1
CD151 CD151 molecule (Raph blood group)
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CHPF chondroitin polymerizing factor
CKLF chemokine-like factor
COMMD3 COMM domain containing 3
COMMD8 COMM domain containing 8
COQ3 coenzyme Q3 methyltransferase
CPOX coproporphyrinogen oxidase
CST3 cystatin C
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1
DBF4 DBF4 zinc finger
DDT D-dopachrome tautomerase
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10
DEXI Dexi homolog (mouse)
DROSHA drosha, ribonuclease type III
DUSP12 dual specificity phosphatase 12
DYNLL1 dynein, light chain, LC8-type 1
ECI1 enoyl-CoA delta isomerase 1
EMP2 epithelial membrane protein 2
ENDOG endonuclease G
FOXK2 forkhead box K2
GEMIN6 gem (nuclear organelle) associated protein 6
GFOD1 glucose-fructose oxidoreductase domain containing 1
GGCT gamma-glutamylcyclotransferase
GOLPH3 golgi phosphoprotein 3 (coat-protein)
GRIP2 glutamate receptor interacting protein 2
GSPT2 G1 to S phase transition 2
H1F0 H1 histone family, member 0
HEBP1 heme binding protein 1
HIST1H2AJ histone cluster 1, H2aj
HMGN3 high mobility group nucleosomal binding domain 3
JUNB jun B proto-oncogene
KAT2B K(lysine) acetyltransferase 2B
KCNMB2 potassium channel subfamily M regulatory beta subunit 2
KIFC1 kinesin family member C1
MAGEC2 melanoma antigen family C2
MED9 mediator complex subunit 9
METTL22 methyltransferase like 22
MRPL28 mitochondrial ribosomal protein L28
MRPS28 mitochondrial ribosomal protein S28
MT2A metallothionein 2A
MTERF3 mitochondrial transcription termination factor 3
MTHFS 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase)
MXRA8 matrix-remodelling associated 8
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2
NOP14 NOP14 nucleolar protein
NUP43 nucleoporin 43kDa
OFD1 oral-facial-digital syndrome 1
PAF1 Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)
PHLDA2 pleckstrin homology-like domain, family A, member 2
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1
POLR3K polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa
PORCN porcupine homolog (Drosophila)
PPIH peptidylprolyl isomerase H (cyclophilin H)
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme
PRKRIR protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor)
PRRC1 proline-rich coiled-coil 1
PTGES2 prostaglandin E synthase 2
RBM15 RNA binding motif protein 15
REEP4 receptor accessory protein 4
RNF167 ring finger protein 167
RPS15A ribosomal protein S15a
RPS25 ribosomal protein S25
SAP130 Sin3A-associated protein, 130kDa
SCAF8 SR-related CTD-associated factor 8
SDC4 syndecan 4
SFT2D2 SFT2 domain containing 2
SGK1 serum/glucocorticoid regulated kinase 1
SHFM1 split hand/foot malformation (ectrodactyly) type 1
SLC50A1 solute carrier family 50 (sugar efflux transporter), member 1
SMYD3 SET and MYND domain containing 3
SMYD5 SMYD family member 5
SNRPE small nuclear ribonucleoprotein polypeptide E
SNRPF small nuclear ribonucleoprotein polypeptide F
TAOK1 TAO kinase 1
TARBP2 TAR (HIV-1) RNA binding protein 2
TECR trans-2,3-enoyl-CoA reductase
TMEM14A transmembrane protein 14A
TMEM185B transmembrane protein 185B
TOM1 target of myb1 (chicken)
UFM1 ubiquitin-fold modifier 1
UQCR10 ubiquinol-cytochrome c reductase, complex III subunit X
UROS uroporphyrinogen III synthase
WDR18 WD repeat domain 18
XPOT exportin, tRNA
ZMYM3 zinc finger, MYM-type 3