Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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196 genes differentially expressed following the 15-delta prostaglandin J2-564 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
ACBD3 | acyl-CoA binding domain containing 3 |
ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 |
ADAP1 | ArfGAP with dual PH domains 1 |
ATM | ATM serine/threonine kinase |
AURKB | aurora kinase B |
CA1 | carbonic anhydrase I |
CACFD1 | calcium channel flower domain containing 1 |
CASP4 | caspase 4, apoptosis-related cysteine peptidase |
CCNJL | cyclin J-like |
CD22 | CD22 molecule |
CD2BP2 | CD2 (cytoplasmic tail) binding protein 2 |
CD79A | CD79a molecule, immunoglobulin-associated alpha |
CLN6 | ceroid-lipofuscinosis, neuronal 6, late infantile, variant |
COL1A1 | collagen, type I, alpha 1 |
CRK | v-crk avian sarcoma virus CT10 oncogene homolog |
DAXX | death-domain associated protein |
DHFR | dihydrofolate reductase |
DHRS9 | dehydrogenase/reductase (SDR family) member 9 |
DLGAP4 | discs, large (Drosophila) homolog-associated protein 4 |
DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
DRG2 | developmentally regulated GTP binding protein 2 |
DYSF | dysferlin |
EGFR | epidermal growth factor receptor |
EMD | emerin |
ERN2 | endoplasmic reticulum to nucleus signaling 2 |
FAM168A | family with sequence similarity 168, member A |
FKBP8 | FK506 binding protein 8, 38kDa |
FUT6 | fucosyltransferase 6 (alpha (1,3) fucosyltransferase) |
FXR2 | fragile X mental retardation, autosomal homolog 2 |
GCLM | glutamate-cysteine ligase, modifier subunit |
GNS | glucosamine (N-acetyl)-6-sulfatase |
GPRIN2 | G protein regulated inducer of neurite outgrowth 2 |
HECW1 | HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 |
HMOX1 | heme oxygenase 1 |
HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 |
HNRNPUL2 | heterogeneous nuclear ribonucleoprotein U-like 2 |
ICAM1 | intercellular adhesion molecule 1 |
IDH3G | isocitrate dehydrogenase 3 (NAD+) gamma |
IFT46 | intraflagellar transport 46 |
IL27RA | interleukin 27 receptor, alpha |
JADE1 | jade family PHD finger 1 |
KDM2A | lysine (K)-specific demethylase 2A |
KLHDC3 | kelch domain containing 3 |
KPNA4 | karyopherin alpha 4 (importin alpha 3) |
LGALS8 | lectin, galactoside-binding, soluble, 8 |
LIF | leukemia inhibitory factor |
LMNA | lamin A/C |
MASP2 | mannan-binding lectin serine peptidase 2 |
MBOAT7 | membrane bound O-acyltransferase domain containing 7 |
MMP17 | matrix metallopeptidase 17 (membrane-inserted) |
MT1E | metallothionein 1E |
MTPAP | mitochondrial poly(A) polymerase |
MYO15B | myosin XVB |
NDE1 | nudE neurodevelopment protein 1 |
OGDHL | oxoglutarate dehydrogenase-like |
OGFR | opioid growth factor receptor |
PATZ1 | POZ (BTB) and AT hook containing zinc finger 1 |
PCDHGB5 | protocadherin gamma subfamily B, 5 |
PHLDB1 | pleckstrin homology-like domain, family B, member 1 |
PIK3CD | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta |
PLCG1 | phospholipase C, gamma 1 |
PLD2 | phospholipase D2 |
PNPLA6 | patatin-like phospholipase domain containing 6 |
PRKACA | protein kinase, cAMP-dependent, catalytic, alpha |
PTP4A3 | protein tyrosine phosphatase type IVA, member 3 |
RAB3GAP2 | RAB3 GTPase activating protein subunit 2 (non-catalytic) |
RAMP3 | receptor (G protein-coupled) activity modifying protein 3 |
RANBP3 | RAN binding protein 3 |
RBM12B | RNA binding motif protein 12B |
RBM15B | RNA binding motif protein 15B |
RMND5B | required for meiotic nuclear division 5 homolog B (S. cerevisiae) |
RPLP2 | ribosomal protein, large, P2 |
SEC24C | SEC24 family member C |
SERP1 | stress-associated endoplasmic reticulum protein 1 |
SGSM2 | small G protein signaling modulator 2 |
SLC17A5 | solute carrier family 17 (acidic sugar transporter), member 5 |
SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8 |
SNW1 | SNW domain containing 1 |
SPDEF | SAM pointed domain containing ETS transcription factor |
SRPK2 | SRSF protein kinase 2 |
STX1A | syntaxin 1A (brain) |
TAGLN2 | transgelin 2 |
TBC1D4 | TBC1 domain family, member 4 |
TMEM134 | transmembrane protein 134 |
TNFRSF25 | tumor necrosis factor receptor superfamily, member 25 |
TRIM16 | tripartite motif containing 16 |
TRMT61A | tRNA methyltransferase 61A |
TRRAP | transformation/transcription domain-associated protein |
UIMC1 | ubiquitin interaction motif containing 1 |
WDTC1 | WD and tetratricopeptide repeats 1 |
XPC | xeroderma pigmentosum, complementation group C |
ZDHHC18 | zinc finger, DHHC-type containing 18 |
ZKSCAN3 | zinc finger with KRAB and SCAN domains 3 |
ZMYM4 | zinc finger, MYM-type 4 |
ZNF277 | zinc finger protein 277 |
ZNF43 | zinc finger protein 43 |
ZNF747 | zinc finger protein 747 |
Symbol | Name |
---|---|
AATK | apoptosis-associated tyrosine kinase |
ANKRD49 | ankyrin repeat domain 49 |
ARL4A | ADP-ribosylation factor-like 4A |
ATPIF1 | ATPase inhibitory factor 1 |
BCL7C | B-cell CLL/lymphoma 7C |
BEX1 | brain expressed, X-linked 1 |
C11ORF48 | |
C1QTNF1 | C1q and tumor necrosis factor related protein 1 |
CA14 | carbonic anhydrase XIV |
CBY1 | chibby homolog 1 (Drosophila) |
CCNL1 | cyclin L1 |
CD151 | CD151 molecule (Raph blood group) |
CDC42EP1 | CDC42 effector protein (Rho GTPase binding) 1 |
CHPF | chondroitin polymerizing factor |
CKLF | chemokine-like factor |
COMMD3 | COMM domain containing 3 |
COMMD8 | COMM domain containing 8 |
COQ3 | coenzyme Q3 methyltransferase |
CPOX | coproporphyrinogen oxidase |
CST3 | cystatin C |
CYP27A1 | cytochrome P450, family 27, subfamily A, polypeptide 1 |
DBF4 | DBF4 zinc finger |
DDT | D-dopachrome tautomerase |
DDX10 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 |
DEXI | Dexi homolog (mouse) |
DROSHA | drosha, ribonuclease type III |
DUSP12 | dual specificity phosphatase 12 |
DYNLL1 | dynein, light chain, LC8-type 1 |
ECI1 | enoyl-CoA delta isomerase 1 |
EMP2 | epithelial membrane protein 2 |
ENDOG | endonuclease G |
FOXK2 | forkhead box K2 |
GEMIN6 | gem (nuclear organelle) associated protein 6 |
GFOD1 | glucose-fructose oxidoreductase domain containing 1 |
GGCT | gamma-glutamylcyclotransferase |
GOLPH3 | golgi phosphoprotein 3 (coat-protein) |
GRIP2 | glutamate receptor interacting protein 2 |
GSPT2 | G1 to S phase transition 2 |
H1F0 | H1 histone family, member 0 |
HEBP1 | heme binding protein 1 |
HIST1H2AJ | histone cluster 1, H2aj |
HMGN3 | high mobility group nucleosomal binding domain 3 |
JUNB | jun B proto-oncogene |
KAT2B | K(lysine) acetyltransferase 2B |
KCNMB2 | potassium channel subfamily M regulatory beta subunit 2 |
KIFC1 | kinesin family member C1 |
MAGEC2 | melanoma antigen family C2 |
MARCKSL1 | MARCKS-like 1 |
MED9 | mediator complex subunit 9 |
METTL22 | methyltransferase like 22 |
MRPL28 | mitochondrial ribosomal protein L28 |
MRPS28 | mitochondrial ribosomal protein S28 |
MT2A | metallothionein 2A |
MTERF3 | mitochondrial transcription termination factor 3 |
MTHFS | 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase) |
MXRA8 | matrix-remodelling associated 8 |
MYBL2 | v-myb avian myeloblastosis viral oncogene homolog-like 2 |
NOP14 | NOP14 nucleolar protein |
NUP43 | nucleoporin 43kDa |
OFD1 | oral-facial-digital syndrome 1 |
PAF1 | Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) |
PHLDA2 | pleckstrin homology-like domain, family A, member 2 |
PLCXD1 | phosphatidylinositol-specific phospholipase C, X domain containing 1 |
POLR3K | polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa |
PORCN | porcupine homolog (Drosophila) |
PPIH | peptidylprolyl isomerase H (cyclophilin H) |
PPP1CA | protein phosphatase 1, catalytic subunit, alpha isozyme |
PRKRIR | protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor) |
PRRC1 | proline-rich coiled-coil 1 |
PTGES2 | prostaglandin E synthase 2 |
RBM15 | RNA binding motif protein 15 |
REEP4 | receptor accessory protein 4 |
RNF167 | ring finger protein 167 |
RPS15A | ribosomal protein S15a |
RPS25 | ribosomal protein S25 |
SAP130 | Sin3A-associated protein, 130kDa |
SCAF8 | SR-related CTD-associated factor 8 |
SDC4 | syndecan 4 |
SFT2D2 | SFT2 domain containing 2 |
SGK1 | serum/glucocorticoid regulated kinase 1 |
SHFM1 | split hand/foot malformation (ectrodactyly) type 1 |
SLC50A1 | solute carrier family 50 (sugar efflux transporter), member 1 |
SMYD3 | SET and MYND domain containing 3 |
SMYD5 | SMYD family member 5 |
SNRPE | small nuclear ribonucleoprotein polypeptide E |
SNRPF | small nuclear ribonucleoprotein polypeptide F |
TAOK1 | TAO kinase 1 |
TARBP2 | TAR (HIV-1) RNA binding protein 2 |
TECR | trans-2,3-enoyl-CoA reductase |
TMEM14A | transmembrane protein 14A |
TMEM185B | transmembrane protein 185B |
TOM1 | target of myb1 (chicken) |
UFM1 | ubiquitin-fold modifier 1 |
UQCR10 | ubiquinol-cytochrome c reductase, complex III subunit X |
UROS | uroporphyrinogen III synthase |
WDR18 | WD repeat domain 18 |
XPOT | exportin, tRNA |
ZMYM3 | zinc finger, MYM-type 3 |