Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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197 genes differentially expressed following the 15-delta prostaglandin J2-6948 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
ABHD4 | abhydrolase domain containing 4 |
AKR1C1 | aldo-keto reductase family 1, member C1 |
AKR1C2 | aldo-keto reductase family 1, member C2 |
AKR1C3 | aldo-keto reductase family 1, member C3 |
ALOX12P2 | arachidonate 12-lipoxygenase pseudogene 2 |
ARHGEF2 | Rho/Rac guanine nucleotide exchange factor (GEF) 2 |
ASF1A | anti-silencing function 1A histone chaperone |
ASNS | asparagine synthetase (glutamine-hydrolyzing) |
ASTN2 | astrotactin 2 |
ATF3 | activating transcription factor 3 |
BANP | BTG3 associated nuclear protein |
BLVRA | biliverdin reductase A |
BRF2 | BRF2, RNA polymerase III transcription initiation factor 50 kDa subunit |
C17ORF80 | chromosome 17 open reading frame 80 |
CBR3 | carbonyl reductase 3 |
CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
CEBPB | CCAAT/enhancer binding protein (C/EBP), beta |
CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
CREM | cAMP responsive element modulator |
CYB5R1 | cytochrome b5 reductase 1 |
CYP4F11 | cytochrome P450, family 4, subfamily F, polypeptide 11 |
DDIT3 | DNA-damage-inducible transcript 3 |
DDIT4 | DNA-damage-inducible transcript 4 |
DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) |
DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
DNAJB4 | DnaJ (Hsp40) homolog, subfamily B, member 4 |
DUSP13 | dual specificity phosphatase 13 |
FAM129A | family with sequence similarity 129, member A |
FAM134B | family with sequence similarity 134, member B |
FAS | Fas cell surface death receptor |
FOSL1 | FOS-like antigen 1 |
FTH1 | ferritin, heavy polypeptide 1 |
FYN | FYN proto-oncogene, Src family tyrosine kinase |
GAB2 | GRB2-associated binding protein 2 |
GABARAPL1 | GABA(A) receptor-associated protein like 1 |
GADD45A | growth arrest and DNA-damage-inducible, alpha |
GCLC | glutamate-cysteine ligase, catalytic subunit |
GCLM | glutamate-cysteine ligase, modifier subunit |
GID4 | GID complex subunit 4 |
GPATCH3 | G patch domain containing 3 |
GRB10 | growth factor receptor-bound protein 10 |
HEG1 | heart development protein with EGF-like domains 1 |
HMOX1 | heme oxygenase 1 |
HSPA13 | heat shock protein 70kDa family, member 13 |
HSPA1A | heat shock 70kDa protein 1A |
HSPA4L | heat shock 70kDa protein 4-like |
HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
HSPH1 | heat shock 105kDa/110kDa protein 1 |
IFRD1 | interferon-related developmental regulator 1 |
IL15RA | interleukin 15 receptor, alpha |
IL1R1 | interleukin 1 receptor, type I |
ITM2C | integral membrane protein 2C |
KDM6A | lysine (K)-specific demethylase 6A |
LARP6 | La ribonucleoprotein domain family, member 6 |
LRIF1 | ligand dependent nuclear receptor interacting factor 1 |
MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
MAFG | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G |
MAP1B | microtubule-associated protein 1B |
MAPK8IP3 | mitogen-activated protein kinase 8 interacting protein 3 |
MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase |
ME1 | malic enzyme 1, NADP(+)-dependent, cytosolic |
MIR22HG | MIR22 host gene |
MMP19 | matrix metallopeptidase 19 |
N4BP2L2 | NEDD4 binding protein 2-like 2 |
NDRG1 | N-myc downstream regulated 1 |
NFIL3 | nuclear factor, interleukin 3 regulated |
NUPR1 | nuclear protein, transcriptional regulator, 1 |
OSGIN1 | oxidative stress induced growth inhibitor 1 |
PCNXL2 | pecanex-like 2 (Drosophila) |
PCYT1A | phosphate cytidylyltransferase 1, choline, alpha |
PELO | pelota homolog (Drosophila) |
PIM1 | Pim-1 proto-oncogene, serine/threonine kinase |
PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 |
PPP1R15A | protein phosphatase 1, regulatory subunit 15A |
RIT1 | Ras-like without CAAX 1 |
RNF19B | ring finger protein 19B |
SEC14L1 | SEC14-like 1 (S. cerevisiae) |
SENP6 | SUMO1/sentrin specific peptidase 6 |
SH2B3 | SH2B adaptor protein 3 |
SLC1A4 | solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 |
SLC48A1 | solute carrier family 48 (heme transporter), member 1 |
SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
SNAPC2 | small nuclear RNA activating complex, polypeptide 2, 45kDa |
SQSTM1 | sequestosome 1 |
STX16 | syntaxin 16 |
STYK1 | serine/threonine/tyrosine kinase 1 |
TES | testin LIM domain protein |
TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b |
TRIB3 | tribbles pseudokinase 3 |
TUBA4A | tubulin, alpha 4a |
TXNRD1 | thioredoxin reductase 1 |
ULBP2 | UL16 binding protein 2 |
UNKL | unkempt family zinc finger-like |
VEGFA | vascular endothelial growth factor A |
VLDLR | very low density lipoprotein receptor |
ZFAND5 | zinc finger, AN1-type domain 5 |
ZNF350 | zinc finger protein 350 |
ZNF442 | zinc finger protein 442 |
ZNF571 | zinc finger protein 571 |
Symbol | Name |
---|---|
ABCC6 | ATP-binding cassette, sub-family C (CFTR/MRP), member 6 |
ACKR3 | atypical chemokine receptor 3 |
ADCY6 | adenylate cyclase 6 |
ARHGAP11A | Rho GTPase activating protein 11A |
ARID5B | AT rich interactive domain 5B (MRF1-like) |
ARMCX1 | armadillo repeat containing, X-linked 1 |
AXIN1 | axin 1 |
BACE1 | beta-site APP-cleaving enzyme 1 |
BAMBI | BMP and activin membrane-bound inhibitor |
BRINP3 | bone morphogenetic protein/retinoic acid inducible neural-specific 3 |
C14ORF169 | chromosome 14 open reading frame 169 |
C2ORF44 | chromosome 2 open reading frame 44 |
C5ORF45 | chromosome 5 open reading frame 45 |
CBFA2T3 | core-binding factor, runt domain, alpha subunit 2; translocated to, 3 |
CCNE2 | cyclin E2 |
CENPB | centromere protein B, 80kDa |
CEP72 | centrosomal protein 72kDa |
CISH | cytokine inducible SH2-containing protein |
CLUHP3 | clustered mitochondria (cluA/CLU1) homolog pseudogene 3 |
CTDSP1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 |
CXORF56 | chromosome X open reading frame 56 |
DKK1 | dickkopf WNT signaling pathway inhibitor 1 |
E2F8 | E2F transcription factor 8 |
EFNA1 | ephrin-A1 |
EPHA4 | EPH receptor A4 |
ERCC6L | excision repair cross-complementation group 6-like |
ERF | Ets2 repressor factor |
ESRP2 | epithelial splicing regulatory protein 2 |
FEN1 | flap structure-specific endonuclease 1 |
FOXRED2 | FAD-dependent oxidoreductase domain containing 2 |
FUZ | fuzzy planar cell polarity protein |
GJA1 | gap junction protein, alpha 1, 43kDa |
GLCE | glucuronic acid epimerase |
HILPDA | hypoxia inducible lipid droplet-associated |
HIST1H1D | histone cluster 1, H1d |
HOXC11 | homeobox C11 |
HOXC13 | homeobox C13 |
ICK | intestinal cell (MAK-like) kinase |
IFNGR2 | interferon gamma receptor 2 (interferon gamma transducer 1) |
JUNB | jun B proto-oncogene |
KAT2A | K(lysine) acetyltransferase 2A |
KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 |
KIF20A | kinesin family member 20A |
KIFC1 | kinesin family member C1 |
LINC00115 | long intergenic non-protein coding RNA 115 |
LMBR1L | limb development membrane protein 1-like |
LOC202181 | SUMO-interacting motifs containing 1 pseudogene |
LRIG1 | leucine-rich repeats and immunoglobulin-like domains 1 |
LSM2 | LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae) |
MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B |
MANBA | mannosidase, beta A, lysosomal |
MCM10 | minichromosome maintenance complex component 10 |
MXD3 | MAX dimerization protein 3 |
NBEAL2 | neurobeachin-like 2 |
NCAPH | non-SMC condensin I complex, subunit H |
NINL | ninein-like |
NPY1R | neuropeptide Y receptor Y1 |
NR2F2 | nuclear receptor subfamily 2, group F, member 2 |
P2RY2 | purinergic receptor P2Y, G-protein coupled, 2 |
PARP16 | poly (ADP-ribose) polymerase family, member 16 |
PCP4 | Purkinje cell protein 4 |
PHLPP1 | PH domain and leucine rich repeat protein phosphatase 1 |
PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
PKIA | protein kinase (cAMP-dependent, catalytic) inhibitor alpha |
PPP1R13L | protein phosphatase 1, regulatory subunit 13 like |
PRKCD | protein kinase C, delta |
PRR15L | proline rich 15-like |
PSRC1 | proline/serine-rich coiled-coil 1 |
RAPGEFL1 | Rap guanine nucleotide exchange factor (GEF)-like 1 |
RGS16 | regulator of G-protein signaling 16 |
RGS19 | regulator of G-protein signaling 19 |
RPRM | reprimo, TP53 dependent G2 arrest mediator candidate |
SEMA4C | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C |
SHPK | sedoheptulokinase |
SLC12A9 | solute carrier family 12, member 9 |
SLC2A10 | solute carrier family 2 (facilitated glucose transporter), member 10 |
SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 |
SPIDR | scaffolding protein involved in DNA repair |
STARD13 | StAR-related lipid transfer (START) domain containing 13 |
SULT2B1 | sulfotransferase family, cytosolic, 2B, member 1 |
SYTL2 | synaptotagmin-like 2 |
TMEM104 | transmembrane protein 104 |
TMEM110 | transmembrane protein 110 |
TMEM184B | transmembrane protein 184B |
TPBG | trophoblast glycoprotein |
TRIP10 | thyroid hormone receptor interactor 10 |
TROAP | trophinin associated protein |
TSSC4 | tumor suppressing subtransferable candidate 4 |
TUT1 | terminal uridylyl transferase 1, U6 snRNA-specific |
VASH2 | vasohibin 2 |
VAV3 | vav 3 guanine nucleotide exchange factor |
VPS33A | vacuolar protein sorting 33 homolog A (S. cerevisiae) |
VWA1 | von Willebrand factor A domain containing 1 |
XRCC3 | X-ray repair complementing defective repair in Chinese hamster cells 3 |
ZNF512B | zinc finger protein 512B |
ZNF675 | zinc finger protein 675 |
ZNF692 | zinc finger protein 692 |
ZNF768 | zinc finger protein 768 |