| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | 18β-Glycyrrhetinic acid perturbation in A549 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the 18β-Glycyrrhetinic acid_A549 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.269275 |
| MT2A | metallothionein 2A | 0.191756 |
| RPS19 | ribosomal protein S19 | 0.140944 |
| RPS6 | ribosomal protein S6 | 0.0976132 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.093955 |
| EFNA5 | ephrin-A5 | 0.0892137 |
| RPL12 | ribosomal protein L12 | 0.0858333 |
| FTL | ferritin, light polypeptide | 0.0827281 |
| RPL23 | ribosomal protein L23 | 0.0797465 |
| STC1 | stanniocalcin 1 | 0.0734441 |
| RPLP1 | ribosomal protein, large, P1 | 0.0726326 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0679089 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0657235 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0621826 |
| RPLP0 | ribosomal protein, large, P0 | 0.0565419 |
| RPL11 | ribosomal protein L11 | 0.0552056 |
| RPL26 | ribosomal protein L26 | 0.0550298 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0517717 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0505312 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0504252 |
| RPS17 | ribosomal protein S17 | 0.0498157 |
| RACK1 | receptor for activated C kinase 1 | 0.0473572 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.045976 |
| RPL18 | ribosomal protein L18 | 0.044451 |
| VIM | vimentin | 0.0434987 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0433868 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0431532 |
| RPL36 | ribosomal protein L36 | 0.041863 |
| RPS12 | ribosomal protein S12 | 0.0403269 |
| RPS8 | ribosomal protein S8 | 0.0402319 |
| RPL31 | ribosomal protein L31 | 0.040222 |
| RPS3 | ribosomal protein S3 | 0.0400281 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.039633 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0383237 |
| INTS6 | integrator complex subunit 6 | 0.0369853 |
| EGFR | epidermal growth factor receptor | 0.0368692 |
| ANGPTL4 | angiopoietin-like 4 | 0.0352997 |
| RPL28 | ribosomal protein L28 | 0.0350073 |
| RPL37A | ribosomal protein L37a | 0.0349504 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0348098 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0347911 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0345229 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.034008 |
| ETNK1 | ethanolamine kinase 1 | 0.0335469 |
| RPL19 | ribosomal protein L19 | 0.0335411 |
| WWOX | WW domain containing oxidoreductase | 0.0330618 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0326102 |
| B2M | beta-2-microglobulin | 0.0325576 |
| RPL35A | ribosomal protein L35a | 0.031987 |
| BMP6 | bone morphogenetic protein 6 | 0.0319253 |
| PRKCE | protein kinase C, epsilon | 0.0311515 |
| RPL9 | ribosomal protein L9 | 0.0311089 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0307029 |
| RPL27 | ribosomal protein L27 | 0.0306641 |
| ZC3H12C | zinc finger CCCH-type containing 12C | 0.0295369 |
| RPL7 | ribosomal protein L7 | 0.0291147 |
| RPS2 | ribosomal protein S2 | 0.0285727 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0283575 |
| SP100 | SP100 nuclear antigen | 0.0281415 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0277652 |
| SMYD3 | SET and MYND domain containing 3 | 0.027657 |
| EGR1 | early growth response 1 | 0.0275676 |
| CCDC88A | coiled-coil domain containing 88A | 0.027091 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.026985 |
| RPS27 | ribosomal protein S27 | 0.0260292 |
| RPS5 | ribosomal protein S5 | 0.0259813 |
| GPATCH2L | G patch domain containing 2-like | 0.0257158 |
| RPL13A | ribosomal protein L13a | 0.0256844 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.025353 |
| RPS14 | ribosomal protein S14 | 0.0253103 |
| KLF6 | Kruppel-like factor 6 | 0.0249475 |
| RPL34 | ribosomal protein L34 | 0.0249298 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.0249294 |
| RPL35 | ribosomal protein L35 | 0.0249177 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0247888 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0241839 |
| TGFBR1 | transforming growth factor, beta receptor 1 | 0.0241573 |
| RPS4X | ribosomal protein S4, X-linked | 0.0239479 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.023708 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0235436 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0235339 |
| RPLP2 | ribosomal protein, large, P2 | 0.0228462 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0227579 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | 0.0227562 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0227045 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0224001 |
| ST6GAL2 | ST6 beta-galactosamide alpha-2,6-sialyltranferase 2 | 0.0223487 |
| RPL37 | ribosomal protein L37 | 0.0221504 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0219696 |
| KANK1 | KN motif and ankyrin repeat domains 1 | 0.0217658 |
| KLF12 | Kruppel-like factor 12 | 0.0211321 |
| RPS27L | ribosomal protein S27-like | 0.0210722 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0209203 |
| EXOC6B | exocyst complex component 6B | 0.0208966 |
| SON | SON DNA binding protein | 0.0205055 |
| IRS2 | insulin receptor substrate 2 | 0.0202639 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0202342 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0202238 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0202158 |
| RPL21 | ribosomal protein L21 | 0.0201622 |
| Symbol | Name | Standardized Value |
|---|---|---|
| UBC | ubiquitin C | -0.210211 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | -0.103515 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.092577 |
| RPS27A | ribosomal protein S27a | -0.0802591 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0795285 |
| TXNRD1 | thioredoxin reductase 1 | -0.072018 |
| KRT81 | keratin 81, type II | -0.0718425 |
| ASPH | aspartate beta-hydroxylase | -0.0694336 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0663229 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0646335 |
| ANXA2 | annexin A2 | -0.0607087 |
| PDE10A | phosphodiesterase 10A | -0.0580829 |
| MCL1 | myeloid cell leukemia 1 | -0.0579984 |
| ACTG1 | actin gamma 1 | -0.0576607 |
| CANX | calnexin | -0.0562713 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0558057 |
| AHNAK | AHNAK nucleoprotein | -0.0552038 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0547713 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0527735 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.0520803 |
| CA12 | carbonic anhydrase XII | -0.0511388 |
| RTN4 | reticulon 4 | -0.0498568 |
| SBF2 | SET binding factor 2 | -0.0492514 |
| SPAG9 | sperm associated antigen 9 | -0.0484895 |
| TNIP1 | TNFAIP3 interacting protein 1 | -0.0476601 |
| USP3 | ubiquitin specific peptidase 3 | -0.0475117 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0460576 |
| KCTD9 | potassium channel tetramerization domain containing 9 | -0.0455712 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0455448 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.045118 |
| DGKD | diacylglycerol kinase, delta 130kDa | -0.045041 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0446733 |
| S100A6 | S100 calcium binding protein A6 | -0.0429161 |
| MAP1B | microtubule-associated protein 1B | -0.0426628 |
| USP34 | ubiquitin specific peptidase 34 | -0.0420643 |
| KRT7 | keratin 7, type II | -0.0417479 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0413808 |
| PTMA | prothymosin, alpha | -0.0412676 |
| FLNB | filamin B, beta | -0.0412219 |
| TPM1 | tropomyosin 1 (alpha) | -0.0407776 |
| CALU | calumenin | -0.0407566 |
| AUTS2 | autism susceptibility candidate 2 | -0.0406931 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0401112 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0400775 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0398367 |
| TNS3 | tensin 3 | -0.0392669 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | -0.0379253 |
| ATG7 | autophagy related 7 | -0.0377897 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.037749 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | -0.0375349 |
| ACTN4 | actinin, alpha 4 | -0.0375346 |
| PKM | pyruvate kinase, muscle | -0.0374892 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0367751 |
| PGK1 | phosphoglycerate kinase 1 | -0.0367114 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0366065 |
| HELZ | helicase with zinc finger | -0.0364153 |
| OGA | O-GlcNAcase | -0.0357921 |
| TFG | TRK-fused gene | -0.0354271 |
| SETD5 | SET domain containing 5 | -0.0354198 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0354007 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0353782 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | -0.0352658 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | -0.0351681 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0346187 |
| DENND4A | DENN/MADD domain containing 4A | -0.0344766 |
| S100A10 | S100 calcium binding protein A10 | -0.0339841 |
| NGLY1 | N-glycanase 1 | -0.0338956 |
| CMIP | c-Maf inducing protein | -0.0336821 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | -0.0335767 |
| ZNF207 | zinc finger protein 207 | -0.0326809 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0325187 |
| TPM4 | tropomyosin 4 | -0.0323947 |
| TMOD3 | tropomodulin 3 (ubiquitous) | -0.0323048 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0322619 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0320459 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0319918 |
| TPM3 | tropomyosin 3 | -0.0317228 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0314283 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0313617 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | -0.0313553 |
| NAV2 | neuron navigator 2 | -0.0313009 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0308774 |
| ADAM17 | ADAM metallopeptidase domain 17 | -0.0305967 |
| LSM14A | LSM14A, SCD6 homolog A (S. cerevisiae) | -0.0302793 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0301545 |
| OSMR | oncostatin M receptor | -0.0301448 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.030123 |
| VMP1 | vacuole membrane protein 1 | -0.0298919 |
| VPS13A | vacuolar protein sorting 13 homolog A (S. cerevisiae) | -0.0297137 |
| KPNB1 | karyopherin (importin) beta 1 | -0.029234 |
| CD99 | CD99 molecule | -0.029209 |
| APP | amyloid beta (A4) precursor protein | -0.0290403 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0289864 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0289133 |
| NBAS | neuroblastoma amplified sequence | -0.0289047 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0288814 |
| NUP58 | nucleoporin 58 | -0.0288779 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0286877 |
| TMSB10 | thymosin beta 10 | -0.0286811 |
| ENO1 | enolase 1, (alpha) | -0.0286079 |
