| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | 18β-Glycyrrhetinic acid perturbation in AN3 CA cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the 18β-Glycyrrhetinic acid_AN3 CA drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MEST | mesoderm specific transcript | 0.260275 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0906042 |
| VEGFA | vascular endothelial growth factor A | 0.0764617 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0594801 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.050046 |
| PCBP2 | poly(rC) binding protein 2 | 0.0480123 |
| EGFR | epidermal growth factor receptor | 0.0382573 |
| SIK3 | SIK family kinase 3 | 0.0365382 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | 0.0328958 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0305345 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0299744 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0283299 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0280556 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.027901 |
| RPL3 | ribosomal protein L3 | 0.0272524 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0269657 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0262737 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0262281 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | 0.0259985 |
| TSHZ2 | teashirt zinc finger homeobox 2 | 0.0256869 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0252847 |
| RPS12 | ribosomal protein S12 | 0.0252107 |
| METTL15 | methyltransferase like 15 | 0.0249297 |
| SLK | STE20-like kinase | 0.0246546 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0244091 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0242955 |
| ERBIN | erbb2 interacting protein | 0.0236003 |
| ANO6 | anoctamin 6 | 0.023343 |
| TET2 | tet methylcytosine dioxygenase 2 | 0.0231234 |
| DSTN | destrin (actin depolymerizing factor) | 0.0226798 |
| SNX13 | sorting nexin 13 | 0.0226199 |
| LDHA | lactate dehydrogenase A | 0.0225005 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0222554 |
| EZR | ezrin | 0.0222543 |
| RAD51B | RAD51 paralog B | 0.0221974 |
| JMJD1C | jumonji domain containing 1C | 0.0221796 |
| TTC28 | tetratricopeptide repeat domain 28 | 0.0221296 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0220363 |
| RPL23 | ribosomal protein L23 | 0.0220155 |
| CYP51A1 | cytochrome P450, family 51, subfamily A, polypeptide 1 | 0.0217543 |
| KIF11 | kinesin family member 11 | 0.0216173 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0211802 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0211442 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0210974 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0210766 |
| PPME1 | protein phosphatase methylesterase 1 | 0.020648 |
| PDGFC | platelet derived growth factor C | 0.0204911 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0203068 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0198354 |
| GLI2 | GLI family zinc finger 2 | 0.0197542 |
| TXNRD1 | thioredoxin reductase 1 | 0.0197463 |
| PDE10A | phosphodiesterase 10A | 0.0194706 |
| BRD4 | bromodomain containing 4 | 0.0194462 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0192786 |
| MED13L | mediator complex subunit 13-like | 0.0192174 |
| CLTC | clathrin, heavy chain (Hc) | 0.0191796 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0190659 |
| BOD1L1 | biorientation of chromosomes in cell division 1-like 1 | 0.0189716 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0189553 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0187458 |
| ARHGAP12 | Rho GTPase activating protein 12 | 0.0187247 |
| SCAF11 | SR-related CTD-associated factor 11 | 0.0187095 |
| CCDC6 | coiled-coil domain containing 6 | 0.0187039 |
| EGR1 | early growth response 1 | 0.0186008 |
| MSN | moesin | 0.0185464 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0183958 |
| TM9SF4 | transmembrane 9 superfamily protein member 4 | 0.0183629 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0183298 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0183023 |
| NOTCH2 | notch 2 | 0.0182384 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0179498 |
| VPS13C | vacuolar protein sorting 13 homolog C (S. cerevisiae) | 0.0179478 |
| HSPA4 | heat shock 70kDa protein 4 | 0.0178916 |
| REST | RE1-silencing transcription factor | 0.0178651 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0177803 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | 0.0176865 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0176392 |
| ARL6IP5 | ADP-ribosylation factor-like 6 interacting protein 5 | 0.0176366 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0173832 |
| PTMS | parathymosin | 0.0173485 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0173433 |
| SON | SON DNA binding protein | 0.0173128 |
| SKIL | SKI-like proto-oncogene | 0.017233 |
| HDGF | hepatoma-derived growth factor | 0.017232 |
| RPS2 | ribosomal protein S2 | 0.0170427 |
| BRD2 | bromodomain containing 2 | 0.0166044 |
| UBXN4 | UBX domain protein 4 | 0.0165765 |
| PPP4R2 | protein phosphatase 4, regulatory subunit 2 | 0.0164781 |
| FBXW11 | F-box and WD repeat domain containing 11 | 0.0164672 |
| YLPM1 | YLP motif containing 1 | 0.0162966 |
| FLNA | filamin A, alpha | 0.0160745 |
| TOP1 | topoisomerase (DNA) I | 0.0160674 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | 0.016059 |
| FLNB | filamin B, beta | 0.0160407 |
| WWOX | WW domain containing oxidoreductase | 0.0160242 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0159807 |
| TFCP2 | transcription factor CP2 | 0.0158825 |
| HNRNPUL2 | heterogeneous nuclear ribonucleoprotein U-like 2 | 0.0158553 |
| HMGA1 | high mobility group AT-hook 1 | 0.0158524 |
| ZNF516 | zinc finger protein 516 | 0.0158029 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.169944 |
| PTMA | prothymosin, alpha | -0.146999 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.133072 |
| MGP | matrix Gla protein | -0.109434 |
| PEG10 | paternally expressed 10 | -0.106797 |
| RPLP1 | ribosomal protein, large, P1 | -0.105132 |
| MT2A | metallothionein 2A | -0.0870234 |
| RPS24 | ribosomal protein S24 | -0.0771544 |
| TMSB10 | thymosin beta 10 | -0.076607 |
| CANX | calnexin | -0.0763581 |
| RPL34 | ribosomal protein L34 | -0.0737154 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0692499 |
| TMSB4X | thymosin beta 4, X-linked | -0.0679716 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0648108 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0645221 |
| ACTG1 | actin gamma 1 | -0.0644628 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0638915 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0628677 |
| COL1A2 | collagen, type I, alpha 2 | -0.0626756 |
| RPLP2 | ribosomal protein, large, P2 | -0.0579974 |
| RPL35A | ribosomal protein L35a | -0.0532787 |
| HMGB1 | high mobility group box 1 | -0.0529575 |
| DEK | DEK proto-oncogene | -0.052935 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0526416 |
| BCOR | BCL6 corepressor | -0.0497421 |
| RPL11 | ribosomal protein L11 | -0.0486975 |
| RPL19 | ribosomal protein L19 | -0.0486261 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0483722 |
| RPLP0 | ribosomal protein, large, P0 | -0.0483271 |
| IER3 | immediate early response 3 | -0.0466675 |
| FGFR1 | fibroblast growth factor receptor 1 | -0.0447816 |
| AK1 | adenylate kinase 1 | -0.0427684 |
| OGA | O-GlcNAcase | -0.0421073 |
| RPS8 | ribosomal protein S8 | -0.0414222 |
| KAZN | kazrin, periplakin interacting protein | -0.0410771 |
| TUBB | tubulin, beta class I | -0.0410136 |
| FBXO11 | F-box protein 11 | -0.0406519 |
| SRPK2 | SRSF protein kinase 2 | -0.0406412 |
| MKI67 | marker of proliferation Ki-67 | -0.0394128 |
| RPS25 | ribosomal protein S25 | -0.0382525 |
| RPL7A | ribosomal protein L7a | -0.0381366 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0377442 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0373278 |
| CCNI | cyclin I | -0.0363656 |
| VCL | vinculin | -0.0361684 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0360697 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0355289 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0348965 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0346194 |
| RPL28 | ribosomal protein L28 | -0.0342833 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0339658 |
| RPL38 | ribosomal protein L38 | -0.0339512 |
| CALR | calreticulin | -0.033518 |
| RPS19 | ribosomal protein S19 | -0.033371 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0332956 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | -0.0331241 |
| RPL8 | ribosomal protein L8 | -0.0329354 |
| RPL12 | ribosomal protein L12 | -0.0313082 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0305844 |
| TBCA | tubulin folding cofactor A | -0.0305795 |
| RPS15 | ribosomal protein S15 | -0.0304631 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0304439 |
| RAD21 | RAD21 homolog (S. pombe) | -0.030401 |
| ZNF292 | zinc finger protein 292 | -0.0299356 |
| KLHL24 | kelch-like family member 24 | -0.0295263 |
| TFDP2 | transcription factor Dp-2 (E2F dimerization partner 2) | -0.0295002 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0294265 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.029424 |
| RHEB | Ras homolog enriched in brain | -0.0291928 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0280423 |
| RPS21 | ribosomal protein S21 | -0.0277699 |
| LMO4 | LIM domain only 4 | -0.0276991 |
| RPL37 | ribosomal protein L37 | -0.0276679 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0273519 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0272285 |
| RPS11 | ribosomal protein S11 | -0.0270379 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0268978 |
| RPS16 | ribosomal protein S16 | -0.0265816 |
| SRP14 | signal recognition particle 14kDa (homologous Alu RNA binding protein) | -0.0265545 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0263687 |
| FUS | FUS RNA binding protein | -0.026347 |
| MTDH | metadherin | -0.026209 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0261876 |
| RPS27 | ribosomal protein S27 | -0.0260858 |
| SHROOM3 | shroom family member 3 | -0.0256159 |
| FOXC1 | forkhead box C1 | -0.025475 |
| G3BP2 | GTPase activating protein (SH3 domain) binding protein 2 | -0.0253665 |
| RNF216 | ring finger protein 216 | -0.0247045 |
| RPS10 | ribosomal protein S10 | -0.0245071 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0242856 |
| SEPTIN11 | septin 11 | -0.024224 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.024156 |
| RPF2 | ribosome production factor 2 homolog (S. cerevisiae) | -0.024058 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0239077 |
| MT1X | metallothionein 1X | -0.0238296 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.023794 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0236801 |
| RPAP2 | RNA polymerase II associated protein 2 | -0.0235874 |
| RPL32 | ribosomal protein L32 | -0.0235216 |
| BMPR1A | bone morphogenetic protein receptor, type IA | -0.023508 |
