| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | 18β-Glycyrrhetinic acid perturbation in BT-474 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the 18β-Glycyrrhetinic acid_BT-474 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| RPL23 | ribosomal protein L23 | 0.0997991 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0786679 |
| CATSPERB | catsper channel auxiliary subunit beta | 0.069351 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0628819 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0585446 |
| INTS6 | integrator complex subunit 6 | 0.0583601 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0576238 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0548881 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0544066 |
| CDK12 | cyclin-dependent kinase 12 | 0.0533512 |
| CLTC | clathrin, heavy chain (Hc) | 0.0456952 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0452656 |
| DTNA | dystrobrevin, alpha | 0.0444634 |
| RPL19 | ribosomal protein L19 | 0.043727 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.042172 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | 0.0420332 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.041599 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0394175 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0386337 |
| RPS3 | ribosomal protein S3 | 0.0385551 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0384297 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0369563 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0368485 |
| RCOR1 | REST corepressor 1 | 0.0356656 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0355993 |
| TRPS1 | trichorhinophalangeal syndrome I | 0.0355723 |
| CEP250 | centrosomal protein 250kDa | 0.0355253 |
| SYNRG | synergin, gamma | 0.0354956 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0351815 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.034891 |
| PATJ | PATJ crumbs cell polarity complex component | 0.0341932 |
| EHMT1 | euchromatic histone-lysine N-methyltransferase 1 | 0.0332826 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0324172 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | 0.0321626 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0319414 |
| ATF6 | activating transcription factor 6 | 0.0315436 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0313197 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0311845 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0309418 |
| UQCC1 | ubiquinol-cytochrome c reductase complex assembly factor 1 | 0.030748 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0306052 |
| VCP | valosin containing protein | 0.0298384 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0295632 |
| PSMD3 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 | 0.029334 |
| ADIPOR2 | adiponectin receptor 2 | 0.0292745 |
| STXBP4 | syntaxin binding protein 4 | 0.0292612 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0292384 |
| RPS6KB1 | ribosomal protein S6 kinase, 70kDa, polypeptide 1 | 0.0291811 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | 0.0291013 |
| KRT8 | keratin 8, type II | 0.0290643 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0289983 |
| MIPOL1 | mirror-image polydactyly 1 | 0.0285488 |
| MAPK8 | mitogen-activated protein kinase 8 | 0.0285158 |
| VMP1 | vacuole membrane protein 1 | 0.0282608 |
| LMNA | lamin A/C | 0.028118 |
| GPATCH2L | G patch domain containing 2-like | 0.0281026 |
| SMYD3 | SET and MYND domain containing 3 | 0.0278948 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | 0.0277432 |
| RPS17 | ribosomal protein S17 | 0.0275635 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0268438 |
| DENND1A | DENN/MADD domain containing 1A | 0.026669 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0265721 |
| CDK13 | cyclin-dependent kinase 13 | 0.0265076 |
| SCFD1 | sec1 family domain containing 1 | 0.0259966 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0258716 |
| HOMER1 | homer scaffolding protein 1 | 0.0258311 |
| SP100 | SP100 nuclear antigen | 0.0257642 |
| PARD3 | par-3 family cell polarity regulator | 0.0257248 |
| KRT86 | keratin 86, type II | 0.0257242 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0255297 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0254596 |
| RBM47 | RNA binding motif protein 47 | 0.0249302 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0246154 |
| VCL | vinculin | 0.0244667 |
| RPL12 | ribosomal protein L12 | 0.0243959 |
| EIF5B | eukaryotic translation initiation factor 5B | 0.0242548 |
| TMSB10 | thymosin beta 10 | 0.0242422 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0242355 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0239689 |
| PRRC2B | proline-rich coiled-coil 2B | 0.0239451 |
| MAP7 | microtubule-associated protein 7 | 0.0238614 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.023828 |
| ENO1 | enolase 1, (alpha) | 0.0236239 |
| EXOC4 | exocyst complex component 4 | 0.023343 |
| PLSCR2 | phospholipid scramblase 2 | 0.0230797 |
| RC3H1 | ring finger and CCCH-type domains 1 | 0.0229761 |
| UBAP2 | ubiquitin associated protein 2 | 0.0228763 |
| RTN3 | reticulon 3 | 0.0228488 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.0228467 |
| VAPB | VAMP (vesicle-associated membrane protein)-associated protein B and C | 0.0228196 |
| COBL | cordon-bleu WH2 repeat protein | 0.0226196 |
| AEBP2 | AE binding protein 2 | 0.0224888 |
| JMJD1C | jumonji domain containing 1C | 0.0224369 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | 0.0223839 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A | 0.0223815 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0220981 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0218915 |
| MIB1 | mindbomb E3 ubiquitin protein ligase 1 | 0.021854 |
| AFDN | afadin, adherens junction formation factor | 0.0217392 |
| PLEKHG4B | pleckstrin homology domain containing, family G (with RhoGef domain) member 4B | 0.02139 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FTH1 | ferritin, heavy polypeptide 1 | -0.110156 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0762669 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | -0.0674733 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0670993 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0513561 |
| TMEM165 | transmembrane protein 165 | -0.0511265 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0478442 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.0474237 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0470696 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0447447 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0370566 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0367583 |
| KDM7A | lysine (K)-specific demethylase 7A | -0.0366738 |
| TMEM123 | transmembrane protein 123 | -0.0366067 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0345716 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.033762 |
| TMC5 | transmembrane channel-like 5 | -0.0327105 |
| PTMA | prothymosin, alpha | -0.0312897 |
| OSMR | oncostatin M receptor | -0.0305452 |
| KIAA1217 | KIAA1217 | -0.0302787 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0295031 |
| FDPS | farnesyl diphosphate synthase | -0.0283006 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0280389 |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 | -0.0279754 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | -0.0273818 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0270172 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0266303 |
| MT2A | metallothionein 2A | -0.0265854 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | -0.026122 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0260274 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0259382 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0256808 |
| SDC4 | syndecan 4 | -0.0255429 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0255115 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0254078 |
| S100A8 | S100 calcium binding protein A8 | -0.0249347 |
| CDH15 | cadherin 15, type 1, M-cadherin (myotubule) | -0.024768 |
| VAV3 | vav 3 guanine nucleotide exchange factor | -0.0246186 |
| INSR | insulin receptor | -0.0244916 |
| WDR45B | WD repeat domain 45B | -0.0242604 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0237969 |
| RHPN2 | rhophilin, Rho GTPase binding protein 2 | -0.0237433 |
| ANXA2 | annexin A2 | -0.0236105 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0235286 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.0233511 |
| USP53 | ubiquitin specific peptidase 53 | -0.0228504 |
| S100A9 | S100 calcium binding protein A9 | -0.0224823 |
| RIOK3 | RIO kinase 3 | -0.0223624 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | -0.0222677 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0217975 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.02157 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0210928 |
| NUP58 | nucleoporin 58 | -0.0210777 |
| RNF24 | ring finger protein 24 | -0.0205811 |
| FAM13A | family with sequence similarity 13, member A | -0.0204296 |
| USP3 | ubiquitin specific peptidase 3 | -0.0204163 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | -0.020378 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0203755 |
| ANXA5 | annexin A5 | -0.0199576 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0198956 |
| CLU | clusterin | -0.0196532 |
| FADS2 | fatty acid desaturase 2 | -0.0194765 |
| TPCN1 | two pore segment channel 1 | -0.0190939 |
| CCNL1 | cyclin L1 | -0.0190241 |
| RIPK2 | receptor-interacting serine-threonine kinase 2 | -0.0190144 |
| SYAP1 | synapse associated protein 1 | -0.0189717 |
| TPM4 | tropomyosin 4 | -0.018656 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0186324 |
| SLFN5 | schlafen family member 5 | -0.0183815 |
| RTN4 | reticulon 4 | -0.0183806 |
| LYN | LYN proto-oncogene, Src family tyrosine kinase | -0.0181348 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0181259 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0179563 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.017955 |
| ABHD17C | abhydrolase domain containing 17C | -0.0179478 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.017806 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0177195 |
| TNNC1 | troponin C type 1 (slow) | -0.0176429 |
| TFG | TRK-fused gene | -0.0174292 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0173114 |
| RAB27B | RAB27B, member RAS oncogene family | -0.0170489 |
| UBE2Z | ubiquitin-conjugating enzyme E2Z | -0.017014 |
| MLLT6 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6 | -0.0169365 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0169162 |
| RPS6 | ribosomal protein S6 | -0.0168861 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0168514 |
| S100A14 | S100 calcium binding protein A14 | -0.0167335 |
| NDUFV2 | NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa | -0.0165715 |
| CCNI | cyclin I | -0.0165515 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | -0.0165142 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0165002 |
| EGR1 | early growth response 1 | -0.0164221 |
| MSMO1 | methylsterol monooxygenase 1 | -0.016199 |
| PNPLA8 | patatin-like phospholipase domain containing 8 | -0.0160611 |
| GRB7 | growth factor receptor-bound protein 7 | -0.0160175 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0159579 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | -0.0158366 |
| TMOD3 | tropomodulin 3 (ubiquitous) | -0.0156947 |
| GBP2 | guanylate binding protein 2, interferon-inducible | -0.015665 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0156033 |
