| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | 18β-Glycyrrhetinic acid perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the 18β-Glycyrrhetinic acid_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NALF1 | NALCN channel auxiliary factor 1 | 0.104387 |
| FMN1 | formin 1 | 0.0912795 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0609204 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0511758 |
| ASPH | aspartate beta-hydroxylase | 0.0477195 |
| VCL | vinculin | 0.0468771 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0461572 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0457332 |
| ATXN1 | ataxin 1 | 0.0411001 |
| B2M | beta-2-microglobulin | 0.0391883 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0384823 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.0373371 |
| KLHL13 | kelch-like family member 13 | 0.035073 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0346511 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0329275 |
| DPH6 | diphthamine biosynthesis 6 | 0.0326201 |
| FN1 | fibronectin 1 | 0.0300309 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0294096 |
| EIF5B | eukaryotic translation initiation factor 5B | 0.0293676 |
| HLA-A | major histocompatibility complex, class I, A | 0.0285238 |
| NDRG1 | N-myc downstream regulated 1 | 0.0281198 |
| NPAS2 | neuronal PAS domain protein 2 | 0.027767 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0277112 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0274803 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0274439 |
| DCAF7 | DDB1 and CUL4 associated factor 7 | 0.0274237 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0273944 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0273912 |
| FHIT | fragile histidine triad | 0.0272271 |
| CXXC5 | CXXC finger protein 5 | 0.0271272 |
| SCFD1 | sec1 family domain containing 1 | 0.0271249 |
| ADNP | activity-dependent neuroprotector homeobox | 0.0268686 |
| WWOX | WW domain containing oxidoreductase | 0.0265786 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0265155 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0261706 |
| RPL37 | ribosomal protein L37 | 0.0261661 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0260707 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0260498 |
| RSF1 | remodeling and spacing factor 1 | 0.0256438 |
| YAP1 | Yes-associated protein 1 | 0.0255836 |
| DARS1 | aspartyl-tRNA synthetase 1 | 0.0254441 |
| RPL37A | ribosomal protein L37a | 0.0251998 |
| GLIS3 | GLIS family zinc finger 3 | 0.0245529 |
| HLA-B | major histocompatibility complex, class I, B | 0.024428 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0242342 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0242306 |
| UBXN4 | UBX domain protein 4 | 0.0240238 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0238105 |
| CCDC57 | coiled-coil domain containing 57 | 0.0236817 |
| TTC17 | tetratricopeptide repeat domain 17 | 0.0233989 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0233568 |
| RPL5 | ribosomal protein L5 | 0.0229596 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0228316 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | 0.022752 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | 0.0227258 |
| VEGFA | vascular endothelial growth factor A | 0.0224442 |
| TAOK3 | TAO kinase 3 | 0.0224074 |
| RBM25 | RNA binding motif protein 25 | 0.0222683 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0219422 |
| SOX4 | SRY (sex determining region Y)-box 4 | 0.021901 |
| MRPS6 | mitochondrial ribosomal protein S6 | 0.021812 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0217791 |
| INHBA | inhibin, beta A | 0.021762 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0216599 |
| GATA3 | GATA binding protein 3 | 0.0214774 |
| GANAB | glucosidase, alpha; neutral AB | 0.0214573 |
| CAB39 | calcium binding protein 39 | 0.0212527 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.0212225 |
| LDHA | lactate dehydrogenase A | 0.0211812 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.0211507 |
| MEF2A | myocyte enhancer factor 2A | 0.0210708 |
| SIK2 | salt-inducible kinase 2 | 0.0209546 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0208728 |
| EFNA5 | ephrin-A5 | 0.0208068 |
| RET | ret proto-oncogene | 0.0205493 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0205422 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | 0.0204437 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | 0.0204083 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | 0.020331 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0202615 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0202589 |
| AFMID | arylformamidase | 0.0202546 |
| SCAF8 | SR-related CTD-associated factor 8 | 0.0202097 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0201816 |
| RPL31 | ribosomal protein L31 | 0.0198759 |
| ACTN1 | actinin, alpha 1 | 0.0198689 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0196228 |
| SYAP1 | synapse associated protein 1 | 0.019548 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0193654 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0193317 |
| PHF14 | PHD finger protein 14 | 0.019319 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0192632 |
| PCBP2 | poly(rC) binding protein 2 | 0.0192178 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | 0.0191296 |
| ARK2C | arkadia (RNF111) C-terminal like ring finger ubiquitin ligase 2C | 0.0190312 |
| PRELID2 | PRELI domain containing 2 | 0.0188915 |
| SNX9 | sorting nexin 9 | 0.018886 |
| PTPRE | protein tyrosine phosphatase, receptor type, E | 0.0188782 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0187774 |
| COL8A1 | collagen, type VIII, alpha 1 | 0.0187218 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | -0.176247 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.10432 |
| COL3A1 | collagen, type III, alpha 1 | -0.0888475 |
| MEIS2 | Meis homeobox 2 | -0.0775479 |
| VIM | vimentin | -0.0773236 |
| COL1A1 | collagen, type I, alpha 1 | -0.074829 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0715264 |
| HELZ | helicase with zinc finger | -0.0688325 |
| PTMA | prothymosin, alpha | -0.0673612 |
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | -0.0662608 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.0654387 |
| SPAG9 | sperm associated antigen 9 | -0.0651388 |
| SYT1 | synaptotagmin I | -0.0602508 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0550777 |
| LSAMP | limbic system-associated membrane protein | -0.0536785 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.053153 |
| LMNA | lamin A/C | -0.0501089 |
| RPL34 | ribosomal protein L34 | -0.0500315 |
| CEP95 | centrosomal protein 95kDa | -0.0494971 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0491589 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0481033 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0479508 |
| HMGB2 | high mobility group box 2 | -0.0465596 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0451745 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0451544 |
| LPIN1 | lipin 1 | -0.0446384 |
| TRIB2 | tribbles pseudokinase 2 | -0.0442751 |
| AHNAK | AHNAK nucleoprotein | -0.0439799 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0437706 |
| APP | amyloid beta (A4) precursor protein | -0.0433506 |
| CDC27 | cell division cycle 27 | -0.042796 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0416198 |
| USP36 | ubiquitin specific peptidase 36 | -0.0415793 |
| DST | dystonin | -0.0415785 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0411873 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | -0.0411755 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0394308 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0393267 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0392048 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0386898 |
| PCDH9 | protocadherin 9 | -0.0381461 |
| ITGA1 | integrin, alpha 1 | -0.0378618 |
| CLTC | clathrin, heavy chain (Hc) | -0.0378571 |
| RPS6 | ribosomal protein S6 | -0.0377096 |
| HMBOX1 | homeobox containing 1 | -0.0374967 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0371734 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0368552 |
| MBTD1 | mbt domain containing 1 | -0.0368385 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | -0.0364984 |
| PTGES2 | prostaglandin E synthase 2 | -0.0364508 |
| WDR45B | WD repeat domain 45B | -0.0361512 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0361483 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.035553 |
| CCDC47 | coiled-coil domain containing 47 | -0.0350748 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0349084 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0346305 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0341365 |
| ANXA2 | annexin A2 | -0.0338608 |
| HDLBP | high density lipoprotein binding protein | -0.0338141 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0338085 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0335945 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0335202 |
| NRG1 | neuregulin 1 | -0.0332115 |
| FAM13A | family with sequence similarity 13, member A | -0.0328685 |
| CCND1 | cyclin D1 | -0.0324546 |
| SEPTIN2 | septin 2 | -0.0324533 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0322827 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0321887 |
| RPL30 | ribosomal protein L30 | -0.0314548 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0311916 |
| FOXK2 | forkhead box K2 | -0.0307532 |
| RAB1A | RAB1A, member RAS oncogene family | -0.030456 |
| PDZRN3 | PDZ domain containing ring finger 3 | -0.0302901 |
| SCN9A | sodium channel, voltage gated, type IX alpha subunit | -0.0301701 |
| SMARCE1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 | -0.0296518 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0295144 |
| ZC3H11A | zinc finger CCCH-type containing 11A | -0.0292308 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0290626 |
| MSI2 | musashi RNA-binding protein 2 | -0.029016 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | -0.0287851 |
| DDX42 | DEAD (Asp-Glu-Ala-Asp) box helicase 42 | -0.0284853 |
| SEC24D | SEC24 family member D | -0.0282632 |
| CANX | calnexin | -0.0282464 |
| PSMD12 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 | -0.0281812 |
| NCAM2 | neural cell adhesion molecule 2 | -0.0279053 |
| GOLGB1 | golgin B1 | -0.027712 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.0275274 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0274462 |
| PRKCE | protein kinase C, epsilon | -0.0274378 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | -0.0272687 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0272488 |
| RPL23 | ribosomal protein L23 | -0.027231 |
| RNF213 | ring finger protein 213 | -0.0271354 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0271128 |
| TLE4 | transducin-like enhancer of split 4 | -0.0269322 |
| BIRC2 | baculoviral IAP repeat containing 2 | -0.026857 |
| CASC3 | cancer susceptibility candidate 3 | -0.0268456 |
| RUNX1 | runt-related transcription factor 1 | -0.0267524 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0266967 |
| TPR | translocated promoter region, nuclear basket protein | -0.0266614 |
