| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | 18β-Glycyrrhetinic acid perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the 18β-Glycyrrhetinic acid_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| B2M | beta-2-microglobulin | 0.143009 |
| LCN2 | lipocalin 2 | 0.127259 |
| MACC1 | metastasis associated in colon cancer 1 | 0.125497 |
| AREG | amphiregulin | 0.108229 |
| LMO7 | LIM domain 7 | 0.106372 |
| MYO1E | myosin IE | 0.104031 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.100286 |
| MX2 | MX dynamin-like GTPase 2 | 0.0840333 |
| FTL | ferritin, light polypeptide | 0.0802377 |
| STS | steroid sulfatase (microsomal), isozyme S | 0.0773561 |
| TJP1 | tight junction protein 1 | 0.0710111 |
| CLDN4 | claudin 4 | 0.0677617 |
| TMC5 | transmembrane channel-like 5 | 0.066946 |
| EFNB2 | ephrin-B2 | 0.0643725 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.059265 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0545218 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | 0.0512391 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0506667 |
| C6ORF132 | chromosome 6 open reading frame 132 | 0.0505107 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0488278 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0485385 |
| ANXA2 | annexin A2 | 0.0484296 |
| KLF6 | Kruppel-like factor 6 | 0.0483275 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | 0.0482932 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0475832 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0471665 |
| ERBIN | erbb2 interacting protein | 0.0455737 |
| FMN1 | formin 1 | 0.0446042 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.0435798 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0425041 |
| RPL23 | ribosomal protein L23 | 0.0424933 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0421069 |
| LIMA1 | LIM domain and actin binding 1 | 0.0420592 |
| DIAPH1 | diaphanous-related formin 1 | 0.0417076 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0415908 |
| RPS6 | ribosomal protein S6 | 0.0414147 |
| BCL2L1 | BCL2-like 1 | 0.0409975 |
| RNF213 | ring finger protein 213 | 0.0399209 |
| IRS2 | insulin receptor substrate 2 | 0.0393403 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0381327 |
| RPL9 | ribosomal protein L9 | 0.0379699 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) | 0.0378474 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | 0.0378387 |
| PLSCR1 | phospholipid scramblase 1 | 0.0372195 |
| BLZF1 | basic leucine zipper nuclear factor 1 | 0.0369348 |
| MX1 | MX dynamin-like GTPase 1 | 0.0368811 |
| IFITM3 | interferon induced transmembrane protein 3 | 0.0366089 |
| TMSB10 | thymosin beta 10 | 0.0360536 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0359445 |
| EGR1 | early growth response 1 | 0.0350281 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.034975 |
| ZC3H13 | zinc finger CCCH-type containing 13 | 0.0342693 |
| CSTB | cystatin B (stefin B) | 0.0341943 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0340792 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0340448 |
| RPS3 | ribosomal protein S3 | 0.0336842 |
| ITGA6 | integrin, alpha 6 | 0.0336392 |
| S100P | S100 calcium binding protein P | 0.0331579 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0330986 |
| RPS19 | ribosomal protein S19 | 0.0329522 |
| TMEM62 | transmembrane protein 62 | 0.0328836 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | 0.0327048 |
| OCLN | occludin | 0.0315607 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0312163 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0311644 |
| RIGI | RNA sensor RIG-I | 0.0310078 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | 0.0307764 |
| SIPA1L2 | signal-induced proliferation-associated 1 like 2 | 0.0306994 |
| IER2 | immediate early response 2 | 0.0303436 |
| XDH | xanthine dehydrogenase | 0.0303049 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | 0.0303046 |
| STK24 | serine/threonine kinase 24 | 0.0299478 |
| POMP | proteasome maturation protein | 0.0298949 |
| PGK1 | phosphoglycerate kinase 1 | 0.0296015 |
| TPI1 | triosephosphate isomerase 1 | 0.0293113 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0288767 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0286426 |
| RPL12 | ribosomal protein L12 | 0.0282179 |
| ZNF292 | zinc finger protein 292 | 0.027815 |
| CYSTM1 | cysteine-rich transmembrane module containing 1 | 0.0274562 |
| ATP11A | ATPase, class VI, type 11A | 0.027436 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0270069 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0269421 |
| TRIB1 | tribbles pseudokinase 1 | 0.0267989 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0266976 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0263803 |
| SH3RF1 | SH3 domain containing ring finger 1 | 0.0261648 |
| RND3 | Rho family GTPase 3 | 0.0261176 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0258452 |
| TMEM51 | transmembrane protein 51 | 0.0257696 |
| RPLP0 | ribosomal protein, large, P0 | 0.0257455 |
| TOP1 | topoisomerase (DNA) I | 0.025644 |
| RPL18 | ribosomal protein L18 | 0.0253615 |
| RPS14 | ribosomal protein S14 | 0.024927 |
| SPATA13 | spermatogenesis associated 13 | 0.0248808 |
| MCU | mitochondrial calcium uniporter | 0.0247919 |
| VPS37B | vacuolar protein sorting 37 homolog B (S. cerevisiae) | 0.024646 |
| ETV6 | ets variant 6 | 0.0244308 |
| NSMCE2 | non-SMC element 2, MMS21 homolog (S. cerevisiae) | 0.0242881 |
| COX5A | cytochrome c oxidase subunit Va | 0.0242249 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.166712 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.117209 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0890275 |
| CANX | calnexin | -0.081468 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0762107 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0743807 |
| PTMA | prothymosin, alpha | -0.0719324 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.062461 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0617952 |
| FNIP1 | folliculin interacting protein 1 | -0.0524687 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | -0.0489257 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0470555 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0459893 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0431898 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0430346 |
| INTS6 | integrator complex subunit 6 | -0.0416607 |
| AHI1 | Abelson helper integration site 1 | -0.0406464 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0397595 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0385572 |
| PKM | pyruvate kinase, muscle | -0.0384258 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.037567 |
| COG6 | component of oligomeric golgi complex 6 | -0.0374578 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | -0.036217 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0358429 |
| LYZ | lysozyme | -0.0354566 |
| ABHD2 | abhydrolase domain containing 2 | -0.0353837 |
| RBM39 | RNA binding motif protein 39 | -0.0353475 |
| GOLGB1 | golgin B1 | -0.0350714 |
| APP | amyloid beta (A4) precursor protein | -0.0346293 |
| RPL34 | ribosomal protein L34 | -0.0345506 |
| WDR45B | WD repeat domain 45B | -0.0338463 |
| NT5C3A | 5'-nucleotidase, cytosolic IIIA | -0.0331561 |
| AGR2 | anterior gradient 2 | -0.0330919 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0327506 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | -0.0325553 |
| HM13 | histocompatibility (minor) 13 | -0.0324842 |
| CALR | calreticulin | -0.0319226 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0319103 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.031547 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | -0.0310543 |
| ATXN1 | ataxin 1 | -0.0302223 |
| FRMD5 | FERM domain containing 5 | -0.0301326 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0298969 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.029634 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0294504 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0293576 |
| SETD5 | SET domain containing 5 | -0.0291983 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0290712 |
| MORF4L2 | mortality factor 4 like 2 | -0.0286544 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0283488 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | -0.0282724 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0279795 |
| COPA | coatomer protein complex, subunit alpha | -0.0279585 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0275811 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0272538 |
| HDLBP | high density lipoprotein binding protein | -0.0270639 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0266454 |
| AFF1 | AF4/FMR2 family, member 1 | -0.0264761 |
| SEC24D | SEC24 family member D | -0.0260701 |
| BPTF | bromodomain PHD finger transcription factor | -0.025791 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0257751 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0257257 |
| MYO10 | myosin X | -0.0254346 |
| SSH2 | slingshot protein phosphatase 2 | -0.0252659 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0249643 |
| MEIS2 | Meis homeobox 2 | -0.0248607 |
| SRP54 | signal recognition particle 54kDa | -0.0248355 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0247741 |
| TXNIP | thioredoxin interacting protein | -0.0247457 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | -0.0244551 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | -0.0244216 |
| IRF1 | interferon regulatory factor 1 | -0.0243254 |
| MUC20 | mucin 20, cell surface associated | -0.0243095 |
| RAPGEF1 | Rap guanine nucleotide exchange factor (GEF) 1 | -0.0242638 |
| WASF2 | WAS protein family, member 2 | -0.024158 |
| RLF | rearranged L-myc fusion | -0.0241458 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0239258 |
| SBF2 | SET binding factor 2 | -0.0237626 |
| ERO1B | endoplasmic reticulum oxidoreductase 1 beta | -0.0236286 |
| VOPP1 | vesicular, overexpressed in cancer, prosurvival protein 1 | -0.023448 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0234475 |
| TMEM263 | transmembrane protein 263 | -0.0233888 |
| SUCLA2 | succinate-CoA ligase, ADP-forming, beta subunit | -0.0233589 |
| TSC22D2 | TSC22 domain family, member 2 | -0.022999 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0228415 |
| SORBS1 | sorbin and SH3 domain containing 1 | -0.0227225 |
| ZFC3H1 | zinc finger, C3H1-type containing | -0.022701 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0223121 |
| ZNF148 | zinc finger protein 148 | -0.0222941 |
| R3HDM2 | R3H domain containing 2 | -0.0222264 |
| USP34 | ubiquitin specific peptidase 34 | -0.0217098 |
| SLMAP | sarcolemma associated protein | -0.0215721 |
| FDPS | farnesyl diphosphate synthase | -0.0214846 |
| SQSTM1 | sequestosome 1 | -0.021425 |
| MSI2 | musashi RNA-binding protein 2 | -0.0213018 |
| HELZ | helicase with zinc finger | -0.0212855 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0212533 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | -0.0209612 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | -0.0209049 |
| ACTG1 | actin gamma 1 | -0.0207461 |
