| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | 18β-Glycyrrhetinic acid perturbation in HCT15 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the 18β-Glycyrrhetinic acid_HCT15 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.28678 |
| LDHA | lactate dehydrogenase A | 0.0901072 |
| MT2A | metallothionein 2A | 0.0788043 |
| PCBP2 | poly(rC) binding protein 2 | 0.0675105 |
| FTL | ferritin, light polypeptide | 0.0572896 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0550871 |
| SON | SON DNA binding protein | 0.0541062 |
| RAB7A | RAB7A, member RAS oncogene family | 0.049233 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0460087 |
| RPL9 | ribosomal protein L9 | 0.0427985 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0412121 |
| POTEF | POTE ankyrin domain family, member F | 0.0410477 |
| B2M | beta-2-microglobulin | 0.0405193 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0390203 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0369779 |
| TUBA1B | tubulin, alpha 1b | 0.0355888 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0349816 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0346274 |
| EXOC6B | exocyst complex component 6B | 0.034604 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0331504 |
| TMF1 | TATA element modulatory factor 1 | 0.0322888 |
| KDELR1 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 | 0.0311957 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0310099 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0308164 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.0302212 |
| VIM | vimentin | 0.0297705 |
| EZR | ezrin | 0.0295894 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0285525 |
| RIOK3 | RIO kinase 3 | 0.0283926 |
| BTBD10 | BTB (POZ) domain containing 10 | 0.027986 |
| CYP51A1 | cytochrome P450, family 51, subfamily A, polypeptide 1 | 0.0278316 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0269482 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0264637 |
| MYO6 | myosin VI | 0.0262555 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.0253367 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | 0.0251543 |
| LIMA1 | LIM domain and actin binding 1 | 0.0251184 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0250737 |
| PLP2 | proteolipid protein 2 (colonic epithelium-enriched) | 0.0246465 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0238903 |
| NUP58 | nucleoporin 58 | 0.0237596 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0234268 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | 0.0231525 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0230202 |
| RPL21 | ribosomal protein L21 | 0.0229469 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0228053 |
| HMGA1 | high mobility group AT-hook 1 | 0.0227623 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0222695 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0220192 |
| ATP5F1B | ATP synthase F1 subunit beta | 0.0217762 |
| BRD4 | bromodomain containing 4 | 0.0217509 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0217094 |
| NKTR | natural killer cell triggering receptor | 0.0216033 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0215443 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | 0.0215374 |
| KLF10 | Kruppel-like factor 10 | 0.0211826 |
| RBM26 | RNA binding motif protein 26 | 0.0210465 |
| YBX3 | Y box binding protein 3 | 0.0210416 |
| NOTCH2 | notch 2 | 0.0207177 |
| TXNIP | thioredoxin interacting protein | 0.0206144 |
| BRD2 | bromodomain containing 2 | 0.020449 |
| TAF7 | TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa | 0.0203582 |
| AQR | aquarius intron-binding spliceosomal factor | 0.020322 |
| UBXN4 | UBX domain protein 4 | 0.0203029 |
| SSRP1 | structure specific recognition protein 1 | 0.0202 |
| WASHC4 | WASH complex subunit 4 | 0.020185 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0201591 |
| SRP9 | signal recognition particle 9kDa | 0.020058 |
| CCNL1 | cyclin L1 | 0.0199474 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0199274 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0198794 |
| CENPF | centromere protein F, 350/400kDa | 0.0198688 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0197854 |
| RSF1 | remodeling and spacing factor 1 | 0.0196819 |
| MYO10 | myosin X | 0.0195408 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.019485 |
| SERINC1 | serine incorporator 1 | 0.0193751 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0191061 |
| SKAP2 | src kinase associated phosphoprotein 2 | 0.0190939 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0190924 |
| RPL30 | ribosomal protein L30 | 0.0190414 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0189748 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0188307 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0188 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0187877 |
| LMAN1 | lectin, mannose-binding, 1 | 0.0187278 |
| SMC3 | structural maintenance of chromosomes 3 | 0.0187086 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0186029 |
| ENO1 | enolase 1, (alpha) | 0.0184917 |
| GPX4 | glutathione peroxidase 4 | 0.0184246 |
| ARRDC4 | arrestin domain containing 4 | 0.0184169 |
| TJP1 | tight junction protein 1 | 0.0182952 |
| RBM27 | RNA binding motif protein 27 | 0.0180278 |
| ATP13A3 | ATPase type 13A3 | 0.0180158 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0180052 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | 0.0179275 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | 0.017633 |
| CDC42 | cell division cycle 42 | 0.0176009 |
| CD47 | CD47 molecule | 0.0174837 |
| PRSS8 | protease, serine, 8 | 0.0174533 |
| Symbol | Name | Standardized Value |
|---|---|---|
| AHNAK | AHNAK nucleoprotein | -0.165973 |
| PTMA | prothymosin, alpha | -0.134547 |
| FAT1 | FAT atypical cadherin 1 | -0.115367 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.074435 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0741655 |
| RAD51B | RAD51 paralog B | -0.0712171 |
| RPL35A | ribosomal protein L35a | -0.061262 |
| NDRG1 | N-myc downstream regulated 1 | -0.0602358 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0560773 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0547592 |
| RPL34 | ribosomal protein L34 | -0.0539276 |
| MSI2 | musashi RNA-binding protein 2 | -0.052713 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0523754 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0467468 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.046288 |
| TPM4 | tropomyosin 4 | -0.0450262 |
| RPLP1 | ribosomal protein, large, P1 | -0.0444935 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.0441226 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0430581 |
| SERINC5 | serine incorporator 5 | -0.0421257 |
| CANX | calnexin | -0.0414129 |
| RPS6 | ribosomal protein S6 | -0.040945 |
| FHIT | fragile histidine triad | -0.0404838 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0392548 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0381327 |
| CTBP2 | C-terminal binding protein 2 | -0.0371772 |
| SQSTM1 | sequestosome 1 | -0.0367223 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | -0.0352683 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | -0.0342179 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0341747 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0341191 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0339188 |
| RPS8 | ribosomal protein S8 | -0.0337877 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0327517 |
| CUX1 | cut-like homeobox 1 | -0.032253 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0322264 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0318298 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0310661 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | -0.03092 |
| FDPS | farnesyl diphosphate synthase | -0.030439 |
| ZNRF3 | zinc and ring finger 3 | -0.030398 |
| HMGB1 | high mobility group box 1 | -0.0303876 |
| HOOK2 | hook microtubule-tethering protein 2 | -0.0303529 |
| MKI67 | marker of proliferation Ki-67 | -0.0302714 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.0300544 |
| RPL38 | ribosomal protein L38 | -0.029998 |
| TCF12 | transcription factor 12 | -0.0295381 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0294103 |
| EHBP1 | EH domain binding protein 1 | -0.028858 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0284328 |
| RPL7A | ribosomal protein L7a | -0.0284252 |
| SCMH1 | sex comb on midleg homolog 1 (Drosophila) | -0.0276224 |
| SNX14 | sorting nexin 14 | -0.0274161 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0271386 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0270939 |
| DNM2 | dynamin 2 | -0.0270115 |
| ZFHX3 | zinc finger homeobox 3 | -0.0267942 |
| DYM | dymeclin | -0.0267806 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0266518 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0265794 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0265618 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0264929 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0262307 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0260552 |
| PRRC2B | proline-rich coiled-coil 2B | -0.0259795 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0258265 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0257811 |
| RNF213 | ring finger protein 213 | -0.025715 |
| SBF2 | SET binding factor 2 | -0.0255515 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0254559 |
| FBL | fibrillarin | -0.025455 |
| ZNF33A | zinc finger protein 33A | -0.0252454 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0250797 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0248719 |
| ZNF609 | zinc finger protein 609 | -0.0247826 |
| KRT8 | keratin 8, type II | -0.0245425 |
| FOXK2 | forkhead box K2 | -0.0244658 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0243705 |
| SCFD2 | sec1 family domain containing 2 | -0.024338 |
| APP | amyloid beta (A4) precursor protein | -0.0242654 |
| NUP214 | nucleoporin 214kDa | -0.0241703 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | -0.0241581 |
| USP34 | ubiquitin specific peptidase 34 | -0.0235989 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.023552 |
| NSD2 | nuclear receptor binding SET domain protein 2 | -0.023457 |
| CADPS | Ca++-dependent secretion activator | -0.0234206 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | -0.0233505 |
| MCL1 | myeloid cell leukemia 1 | -0.0232957 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0230083 |
| DIAPH2 | diaphanous-related formin 2 | -0.0228679 |
| KDM4B | lysine (K)-specific demethylase 4B | -0.0228122 |
| SMARCA4 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 | -0.0226891 |
| PLEC | plectin | -0.0226676 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | -0.0226619 |
| LRRC23 | leucine rich repeat containing 23 | -0.0225801 |
| RNF216 | ring finger protein 216 | -0.0224266 |
| RPS10 | ribosomal protein S10 | -0.0223884 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0218601 |
| SETD5 | SET domain containing 5 | -0.0216883 |
| SH3BP4 | SH3-domain binding protein 4 | -0.0216665 |
