| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | 18β-Glycyrrhetinic acid perturbation in HEC-1-A cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the 18β-Glycyrrhetinic acid_HEC-1-A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.101193 |
| MT2A | metallothionein 2A | 0.0825035 |
| LDHA | lactate dehydrogenase A | 0.0491735 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0465429 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0426955 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0382656 |
| RPL9 | ribosomal protein L9 | 0.037443 |
| RPS3 | ribosomal protein S3 | 0.0374092 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0362451 |
| ITGB8 | integrin, beta 8 | 0.0345228 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | 0.0330028 |
| LAMA4 | laminin, alpha 4 | 0.0314267 |
| RPS12 | ribosomal protein S12 | 0.0297851 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0278924 |
| TPI1 | triosephosphate isomerase 1 | 0.0263387 |
| RHEX | regulator of hemoglobinization and erythroid cell expansion | 0.0258988 |
| ENO1 | enolase 1, (alpha) | 0.0258093 |
| TUBB4B | tubulin, beta 4B class IVb | 0.0255868 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0252701 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0251045 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0250245 |
| CLDN4 | claudin 4 | 0.0249778 |
| B2M | beta-2-microglobulin | 0.0246523 |
| DSTN | destrin (actin depolymerizing factor) | 0.0246468 |
| STAU2 | staufen double-stranded RNA binding protein 2 | 0.0245951 |
| RPS17 | ribosomal protein S17 | 0.024256 |
| TES | testin LIM domain protein | 0.0240735 |
| DIAPH3 | diaphanous-related formin 3 | 0.0240174 |
| CBX3 | chromobox homolog 3 | 0.0237695 |
| MYADM | myeloid-associated differentiation marker | 0.0235017 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0234879 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0231321 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.023003 |
| HMGA2 | high mobility group AT-hook 2 | 0.0229758 |
| HMGA1 | high mobility group AT-hook 1 | 0.0229529 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0223089 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0221654 |
| BBX | bobby sox homolog (Drosophila) | 0.0220915 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0220536 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0217622 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0216994 |
| RPL30 | ribosomal protein L30 | 0.0213473 |
| RPL37A | ribosomal protein L37a | 0.0212712 |
| CCDC138 | coiled-coil domain containing 138 | 0.0211715 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0211279 |
| DOCK5 | dedicator of cytokinesis 5 | 0.021028 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0209436 |
| TJP1 | tight junction protein 1 | 0.0208391 |
| ITGA6 | integrin, alpha 6 | 0.0206923 |
| POTEF | POTE ankyrin domain family, member F | 0.0206078 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.0204841 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0203304 |
| TUBA1B | tubulin, alpha 1b | 0.0202531 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0201067 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0198146 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0195574 |
| NDUFAF2 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 2 | 0.0195174 |
| NSRP1 | nuclear speckle splicing regulatory protein 1 | 0.0193093 |
| MMS22L | MMS22-like, DNA repair protein | 0.0190497 |
| MACROD2 | MACRO domain containing 2 | 0.0187529 |
| PERP | PERP, TP53 apoptosis effector | 0.0187521 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0184572 |
| RPS13 | ribosomal protein S13 | 0.0181942 |
| ITGAV | integrin, alpha V | 0.0181548 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0179039 |
| NFIB | nuclear factor I/B | 0.0176192 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0172855 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0172342 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 | 0.017183 |
| TMEM87A | transmembrane protein 87A | 0.0171059 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.017051 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0169356 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0168875 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0168075 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | 0.0168027 |
| ZRANB3 | zinc finger, RAN-binding domain containing 3 | 0.0167926 |
| COA1 | cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae) | 0.0165338 |
| VMP1 | vacuole membrane protein 1 | 0.0165122 |
| PLEKHA1 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 | 0.0163404 |
| WEE1 | WEE1 G2 checkpoint kinase | 0.0161456 |
| SRSF5 | serine/arginine-rich splicing factor 5 | 0.0159052 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0158845 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0158656 |
| EGR1 | early growth response 1 | 0.0157226 |
| RPL36AL | ribosomal protein L36a-like | 0.0155122 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | 0.0154719 |
| OXR1 | oxidation resistance 1 | 0.0154062 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | 0.0153506 |
| OFD1 | oral-facial-digital syndrome 1 | 0.015275 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0151959 |
| AXL | AXL receptor tyrosine kinase | 0.0150653 |
| CCDC91 | coiled-coil domain containing 91 | 0.0150564 |
| ATXN1 | ataxin 1 | 0.0149777 |
| RPL21 | ribosomal protein L21 | 0.0149199 |
| IWS1 | IWS1 homolog (S. cerevisiae) | 0.0148818 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0147892 |
| TINAGL1 | tubulointerstitial nephritis antigen-like 1 | 0.0146553 |
| SGMS2 | sphingomyelin synthase 2 | 0.0146346 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0146007 |
| ETV6 | ets variant 6 | 0.0145851 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.156773 |
| AHNAK | AHNAK nucleoprotein | -0.122885 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.120891 |
| ACTG1 | actin gamma 1 | -0.105801 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.103738 |
| APP | amyloid beta (A4) precursor protein | -0.0851446 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0753655 |
| PRELID2 | PRELI domain containing 2 | -0.0663773 |
| H1-0 | H1.0 linker histone | -0.0653466 |
| RPS6 | ribosomal protein S6 | -0.064153 |
| CANX | calnexin | -0.063446 |
| TMSB4X | thymosin beta 4, X-linked | -0.0627567 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0608366 |
| FLNA | filamin A, alpha | -0.0584814 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0581057 |
| ZNF292 | zinc finger protein 292 | -0.0571122 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0553163 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0541732 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.053665 |
| RPLP1 | ribosomal protein, large, P1 | -0.0533313 |
| MATR3 | matrin 3 | -0.0526918 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0512027 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0506858 |
| PLEC | plectin | -0.0489639 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0475416 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0467223 |
| SEPTIN7 | septin 7 | -0.0459154 |
| OGA | O-GlcNAcase | -0.0456803 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0451088 |
| MAP4 | microtubule-associated protein 4 | -0.0447433 |
| GOLGA4 | golgin A4 | -0.0437199 |
| YBX1 | Y box binding protein 1 | -0.0428068 |
| KRT7 | keratin 7, type II | -0.0422141 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0421773 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.041216 |
| ANXA2 | annexin A2 | -0.0403489 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0403361 |
| RLF | rearranged L-myc fusion | -0.0397481 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0396594 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0386502 |
| FLNB | filamin B, beta | -0.0385378 |
| SET | SET nuclear proto-oncogene | -0.0380823 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0377176 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.037668 |
| PRRC2B | proline-rich coiled-coil 2B | -0.0376288 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | -0.0375729 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | -0.0374021 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0373372 |
| HELZ | helicase with zinc finger | -0.0370292 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0361183 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0360774 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0359532 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.0356534 |
| SPAG9 | sperm associated antigen 9 | -0.0356012 |
| USP9X | ubiquitin specific peptidase 9, X-linked | -0.035125 |
| RPL23 | ribosomal protein L23 | -0.0349596 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0348885 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0348807 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | -0.034865 |
| RPS19 | ribosomal protein S19 | -0.0345658 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0344565 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.0343622 |
| RPL14 | ribosomal protein L14 | -0.0339848 |
| HMGB1 | high mobility group box 1 | -0.0333905 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0333502 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0333227 |
| RPL34 | ribosomal protein L34 | -0.0329181 |
| LAMB3 | laminin, beta 3 | -0.0327304 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0327206 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0326908 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0326798 |
| LOC112694756 | uncharaterized LOC112694756 | -0.032588 |
| HSPA8 | heat shock 70kDa protein 8 | -0.0323578 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0321381 |
| MEF2A | myocyte enhancer factor 2A | -0.0319546 |
| FBXO11 | F-box protein 11 | -0.0315666 |
| PKM | pyruvate kinase, muscle | -0.0315 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | -0.031332 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0312323 |
| RPL35A | ribosomal protein L35a | -0.0310935 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0310617 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.030854 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.030837 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | -0.030768 |
| SMAD3 | SMAD family member 3 | -0.0304333 |
| RPS2 | ribosomal protein S2 | -0.0304194 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0301643 |
| KDM4B | lysine (K)-specific demethylase 4B | -0.029914 |
| RPS20 | ribosomal protein S20 | -0.0297971 |
| PUM1 | pumilio RNA-binding family member 1 | -0.0294255 |
| RYBP | RING1 and YY1 binding protein | -0.0292982 |
| EIF4H | eukaryotic translation initiation factor 4H | -0.029295 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.0292696 |
| BDP1 | B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB | -0.0291444 |
| FBXL2 | F-box and leucine-rich repeat protein 2 | -0.0291034 |
| SQSTM1 | sequestosome 1 | -0.02899 |
| CALR | calreticulin | -0.0289269 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.028805 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0286985 |
| MED13 | mediator complex subunit 13 | -0.0285811 |
