| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | 18β-Glycyrrhetinic acid perturbation in HOP62 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the 18β-Glycyrrhetinic acid_HOP62 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.148921 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.141767 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.14164 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0749925 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0672001 |
| ASPH | aspartate beta-hydroxylase | 0.0651874 |
| CLMP | CXADR-like membrane protein | 0.0641554 |
| HMGA2 | high mobility group AT-hook 2 | 0.0639115 |
| TMSB10 | thymosin beta 10 | 0.0635385 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0602923 |
| NDRG1 | N-myc downstream regulated 1 | 0.0601716 |
| INHBA | inhibin, beta A | 0.0597964 |
| COL6A1 | collagen, type VI, alpha 1 | 0.0588225 |
| LDHA | lactate dehydrogenase A | 0.0581504 |
| CD44 | CD44 molecule (Indian blood group) | 0.052895 |
| RCOR1 | REST corepressor 1 | 0.0505479 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.050093 |
| POTEF | POTE ankyrin domain family, member F | 0.0500401 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0498544 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0477143 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0475264 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0461974 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0458595 |
| IGF2 | insulin-like growth factor 2 | 0.0445785 |
| TPI1 | triosephosphate isomerase 1 | 0.0445206 |
| INTS6 | integrator complex subunit 6 | 0.0440349 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0434653 |
| EGFR | epidermal growth factor receptor | 0.0425804 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0425617 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0424486 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0418574 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0409459 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0408113 |
| HLA-A | major histocompatibility complex, class I, A | 0.040394 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.039993 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0384778 |
| VCL | vinculin | 0.0382807 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0372024 |
| IL11 | interleukin 11 | 0.0365872 |
| MAP1B | microtubule-associated protein 1B | 0.0365555 |
| MYO10 | myosin X | 0.036464 |
| ENO1 | enolase 1, (alpha) | 0.0354997 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0351352 |
| MSN | moesin | 0.0351194 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0347285 |
| DST | dystonin | 0.0339396 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0336471 |
| KLF12 | Kruppel-like factor 12 | 0.0334091 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0329569 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0326097 |
| DSTN | destrin (actin depolymerizing factor) | 0.032576 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0323489 |
| RPS3 | ribosomal protein S3 | 0.0322547 |
| GRAMD1B | GRAM domain containing 1B | 0.0315225 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0312336 |
| ATXN1 | ataxin 1 | 0.0306964 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0306796 |
| RRM2 | ribonucleotide reductase M2 | 0.0304574 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.0304282 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0303448 |
| FNDC3A | fibronectin type III domain containing 3A | 0.030264 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0301294 |
| HOMER1 | homer scaffolding protein 1 | 0.0291423 |
| RPS4X | ribosomal protein S4, X-linked | 0.0288057 |
| SYAP1 | synapse associated protein 1 | 0.0286839 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0284489 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0283905 |
| NAV1 | neuron navigator 1 | 0.0283314 |
| CLTC | clathrin, heavy chain (Hc) | 0.0283086 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0282101 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0280667 |
| ACTN1 | actinin, alpha 1 | 0.0279075 |
| PRSS23 | protease, serine, 23 | 0.0278888 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0278749 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0277824 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0275598 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0274336 |
| LMO7 | LIM domain 7 | 0.0274299 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0274131 |
| JAG1 | jagged 1 | 0.0269826 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0268674 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0265538 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0265287 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | 0.0263458 |
| FER | fer (fps/fes related) tyrosine kinase | 0.0263431 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.026051 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0258897 |
| TAGLN2 | transgelin 2 | 0.025644 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | 0.0252458 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0251813 |
| SMYD3 | SET and MYND domain containing 3 | 0.0251726 |
| RPL12 | ribosomal protein L12 | 0.0251498 |
| B2M | beta-2-microglobulin | 0.0250719 |
| HMGA1 | high mobility group AT-hook 1 | 0.0250504 |
| EHBP1 | EH domain binding protein 1 | 0.0250209 |
| TFRC | transferrin receptor | 0.0249748 |
| MT2A | metallothionein 2A | 0.0246854 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0245687 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0244269 |
| C6ORF62 | chromosome 6 open reading frame 62 | 0.0243289 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.214784 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.19245 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.117108 |
| PTMA | prothymosin, alpha | -0.100303 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0902682 |
| CANX | calnexin | -0.0653802 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0550433 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0480443 |
| NGLY1 | N-glycanase 1 | -0.0450376 |
| AHNAK | AHNAK nucleoprotein | -0.0446868 |
| RPLP1 | ribosomal protein, large, P1 | -0.0430098 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0419599 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.040817 |
| LAMB3 | laminin, beta 3 | -0.0393672 |
| RNMT | RNA (guanine-7-) methyltransferase | -0.039165 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0390375 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0378501 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0351769 |
| OGA | O-GlcNAcase | -0.0351148 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.034422 |
| CALR | calreticulin | -0.0343292 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0332434 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0330552 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0320834 |
| RPS6 | ribosomal protein S6 | -0.0307608 |
| GOLGA4 | golgin A4 | -0.0306465 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0301533 |
| IER3 | immediate early response 3 | -0.0300276 |
| CDH13 | cadherin 13 | -0.0298113 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0296272 |
| WDR45B | WD repeat domain 45B | -0.0292555 |
| CDCP1 | CUB domain containing protein 1 | -0.0284381 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0279323 |
| HDLBP | high density lipoprotein binding protein | -0.0276363 |
| GNAS | GNAS complex locus | -0.0274904 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0270351 |
| TUBB6 | tubulin, beta 6 class V | -0.0268176 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0264759 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0264329 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0259084 |
| DNMBP | dynamin binding protein | -0.0258115 |
| POM121 | POM121 transmembrane nucleoporin | -0.0258052 |
| PCBP3 | poly(rC) binding protein 3 | -0.0254237 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0249525 |
| RIN2 | Ras and Rab interactor 2 | -0.0247184 |
| RAB1A | RAB1A, member RAS oncogene family | -0.024634 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0244878 |
| FAM13A | family with sequence similarity 13, member A | -0.0244565 |
| SNX14 | sorting nexin 14 | -0.0243406 |
| EGR1 | early growth response 1 | -0.0242843 |
| TMEM165 | transmembrane protein 165 | -0.0242542 |
| GPC5 | glypican 5 | -0.0242383 |
| ADM | adrenomedullin | -0.023628 |
| CFDP1 | craniofacial development protein 1 | -0.023591 |
| RNF24 | ring finger protein 24 | -0.0234814 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.023168 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0230754 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0229062 |
| RPS29 | ribosomal protein S29 | -0.022882 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | -0.0225198 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0224993 |
| CEP350 | centrosomal protein 350kDa | -0.0224194 |
| TAC4 | tachykinin 4 (hemokinin) | -0.0223528 |
| RASA3 | RAS p21 protein activator 3 | -0.0222771 |
| WASF2 | WAS protein family, member 2 | -0.0222612 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0219502 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | -0.0219166 |
| COL5A1 | collagen, type V, alpha 1 | -0.0217591 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.0216818 |
| PFKP | phosphofructokinase, platelet | -0.0216784 |
| UBA2 | ubiquitin-like modifier activating enzyme 2 | -0.0216658 |
| CAVIN1 | caveolae associated protein 1 | -0.021463 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | -0.0212536 |
| BHLHE41 | basic helix-loop-helix family, member e41 | -0.0211905 |
| RNF149 | ring finger protein 149 | -0.0211588 |
| COL4A2 | collagen, type IV, alpha 2 | -0.020927 |
| AKAP10 | A kinase (PRKA) anchor protein 10 | -0.0204168 |
| E2F7 | E2F transcription factor 7 | -0.0203035 |
| POM121C | POM121 transmembrane nucleoporin C | -0.0202776 |
| RPL14 | ribosomal protein L14 | -0.020274 |
| HOOK2 | hook microtubule-tethering protein 2 | -0.0202347 |
| MMP12 | matrix metallopeptidase 12 | -0.0201 |
| TPM1 | tropomyosin 1 (alpha) | -0.0200828 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.020062 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0198836 |
| RPS20 | ribosomal protein S20 | -0.0198732 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0197929 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0195809 |
| TCF25 | transcription factor 25 (basic helix-loop-helix) | -0.0195803 |
| COG5 | component of oligomeric golgi complex 5 | -0.01926 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | -0.0191306 |
| CALU | calumenin | -0.0191239 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0189894 |
| KLF6 | Kruppel-like factor 6 | -0.0187469 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0186423 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | -0.0183516 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0182753 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0181794 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0181587 |
| FNBP1 | formin binding protein 1 | -0.0181434 |
