| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | 18β-Glycyrrhetinic acid perturbation in HT-29 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the 18β-Glycyrrhetinic acid_HT-29 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NDRG1 | N-myc downstream regulated 1 | 0.133521 |
| RPL23 | ribosomal protein L23 | 0.119374 |
| LMO7 | LIM domain 7 | 0.110832 |
| FTL | ferritin, light polypeptide | 0.107146 |
| LYZ | lysozyme | 0.101033 |
| B2M | beta-2-microglobulin | 0.0893991 |
| POTEF | POTE ankyrin domain family, member F | 0.0794953 |
| VEGFA | vascular endothelial growth factor A | 0.0765749 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0738228 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0692806 |
| LDHA | lactate dehydrogenase A | 0.0675906 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0659972 |
| RPL18 | ribosomal protein L18 | 0.0642697 |
| TMSB10 | thymosin beta 10 | 0.0627379 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.0626156 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0624939 |
| SMAD3 | SMAD family member 3 | 0.0600727 |
| CTBP2 | C-terminal binding protein 2 | 0.0593771 |
| KRT18 | keratin 18, type I | 0.0591876 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0584323 |
| PKM | pyruvate kinase, muscle | 0.057971 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.056882 |
| RPS3 | ribosomal protein S3 | 0.0567098 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.056664 |
| ENO1 | enolase 1, (alpha) | 0.0557456 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0555029 |
| RPS6 | ribosomal protein S6 | 0.0543819 |
| TPI1 | triosephosphate isomerase 1 | 0.053431 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0497913 |
| MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | 0.0487905 |
| DST | dystonin | 0.0487666 |
| TJP1 | tight junction protein 1 | 0.0480008 |
| AREG | amphiregulin | 0.0478757 |
| CLDN4 | claudin 4 | 0.0469321 |
| TES | testin LIM domain protein | 0.0466465 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.045493 |
| ATXN1 | ataxin 1 | 0.0451943 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0446961 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | 0.0444116 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0435893 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0435576 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0435248 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.04254 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0424764 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0421423 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0419084 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0409798 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | 0.0402891 |
| RPS12 | ribosomal protein S12 | 0.0395654 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.039093 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0390547 |
| PCBP2 | poly(rC) binding protein 2 | 0.0389347 |
| TRIB1 | tribbles pseudokinase 1 | 0.0385129 |
| BCL2L1 | BCL2-like 1 | 0.0384894 |
| RPS19 | ribosomal protein S19 | 0.0382617 |
| ZFP36 | ZFP36 ring finger protein | 0.037577 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0375667 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0374333 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0373448 |
| FAT1 | FAT atypical cadherin 1 | 0.0372419 |
| TXNIP | thioredoxin interacting protein | 0.0372073 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0367889 |
| KIF5B | kinesin family member 5B | 0.0367767 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0365524 |
| DSPP | dentin sialophosphoprotein | 0.0363302 |
| HLA-A | major histocompatibility complex, class I, A | 0.0357383 |
| TAGLN2 | transgelin 2 | 0.0356268 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0355746 |
| ABHD2 | abhydrolase domain containing 2 | 0.034975 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0342038 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0337557 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0335165 |
| PLK2 | polo-like kinase 2 | 0.0335146 |
| LIMA1 | LIM domain and actin binding 1 | 0.033484 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.033383 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.0333439 |
| NTN4 | netrin 4 | 0.0329119 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0327143 |
| MSN | moesin | 0.0325843 |
| UTRN | utrophin | 0.0322506 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0321855 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.0316898 |
| ESRP1 | epithelial splicing regulatory protein 1 | 0.0314307 |
| TMEM65 | transmembrane protein 65 | 0.0313989 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0313933 |
| CLTC | clathrin, heavy chain (Hc) | 0.0313504 |
| PGCKA1 | PDCD10 and GCKIII kinases associated 1 | 0.031048 |
| EPCAM | epithelial cell adhesion molecule | 0.030856 |
| FAM13A | family with sequence similarity 13, member A | 0.0307789 |
| ETV6 | ets variant 6 | 0.0307054 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0306034 |
| RPL12 | ribosomal protein L12 | 0.030525 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0304655 |
| RACK1 | receptor for activated C kinase 1 | 0.030186 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0298724 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0295133 |
| GOLGA4 | golgin A4 | 0.0291963 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0290027 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0288864 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0285347 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TPT1 | tumor protein, translationally-controlled 1 | -0.143556 |
| ITPKC | inositol-trisphosphate 3-kinase C | -0.0794555 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0777825 |
| ACTN4 | actinin, alpha 4 | -0.0712713 |
| RPLP1 | ribosomal protein, large, P1 | -0.0708643 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0619123 |
| KRT20 | keratin 20, type I | -0.0544631 |
| ACTG1 | actin gamma 1 | -0.0521246 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0520228 |
| RPL35A | ribosomal protein L35a | -0.0517459 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0470743 |
| SLC45A4 | solute carrier family 45, member 4 | -0.0436457 |
| SDC4 | syndecan 4 | -0.0434279 |
| VCL | vinculin | -0.0421068 |
| NECTIN2 | nectin cell adhesion molecule 2 | -0.0415432 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.0386264 |
| RPS13 | ribosomal protein S13 | -0.0381231 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0371257 |
| FRY | furry homolog (Drosophila) | -0.0350456 |
| RPL13A | ribosomal protein L13a | -0.0346305 |
| MKI67 | marker of proliferation Ki-67 | -0.0344792 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.0332981 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.032929 |
| RPL38 | ribosomal protein L38 | -0.0326679 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0324497 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0321763 |
| RPL34 | ribosomal protein L34 | -0.0321353 |
| HMGB1 | high mobility group box 1 | -0.031899 |
| AHNAK | AHNAK nucleoprotein | -0.0314596 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0307096 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0302753 |
| S100A6 | S100 calcium binding protein A6 | -0.0297165 |
| SQSTM1 | sequestosome 1 | -0.0296578 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0287463 |
| MMP7 | matrix metallopeptidase 7 | -0.0286655 |
| NIBAN2 | niban apoptosis regulator 2 | -0.0286056 |
| NPC1 | Niemann-Pick disease, type C1 | -0.028471 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0283588 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | -0.0279824 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0279026 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.027806 |
| IL6ST | interleukin 6 signal transducer | -0.027383 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0273576 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0272611 |
| S100A10 | S100 calcium binding protein A10 | -0.0271351 |
| MYH14 | myosin, heavy chain 14, non-muscle | -0.0269111 |
| EZR | ezrin | -0.0260484 |
| RHEB | Ras homolog enriched in brain | -0.0250953 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.024823 |
| FUS | FUS RNA binding protein | -0.0247816 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0245443 |
| GNGT1 | guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 | -0.0243815 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0240962 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0238356 |
| TRAPPC9 | trafficking protein particle complex 9 | -0.0238275 |
| AGR2 | anterior gradient 2 | -0.0238024 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0237945 |
| RPL36A | ribosomal protein L36a | -0.0235768 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0230188 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 | -0.0227672 |
| ACACA | acetyl-CoA carboxylase alpha | -0.0227641 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | -0.0225428 |
| KDM4B | lysine (K)-specific demethylase 4B | -0.022496 |
| FOXO3 | forkhead box O3 | -0.0224376 |
| RPS29 | ribosomal protein S29 | -0.02234 |
| RBM39 | RNA binding motif protein 39 | -0.0222092 |
| FBXO32 | F-box protein 32 | -0.0218433 |
| UBE2B | ubiquitin-conjugating enzyme E2B | -0.0218143 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.021726 |
| TRIM56 | tripartite motif containing 56 | -0.0211453 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0209916 |
| MUC13 | mucin 13, cell surface associated | -0.0209911 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.0209711 |
| PRELID2 | PRELI domain containing 2 | -0.0209155 |
| CYRIB | CYFIP related Rac1 interactor B | -0.0207081 |
| IFRD1 | interferon-related developmental regulator 1 | -0.0205238 |
| ATAD2 | ATPase family, AAA domain containing 2 | -0.0200256 |
| DENND5B | DENN/MADD domain containing 5B | -0.0200196 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0198302 |
| DENND1A | DENN/MADD domain containing 1A | -0.0197167 |
| KIAA1958 | KIAA1958 | -0.0196051 |
| TFRC | transferrin receptor | -0.0194717 |
| RPS15 | ribosomal protein S15 | -0.0194599 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | -0.0193507 |
| NPR2 | natriuretic peptide receptor 2 | -0.0192081 |
| GNAS | GNAS complex locus | -0.0191005 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0190321 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0189919 |
| PLEC | plectin | -0.0189884 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0184886 |
| IGF2 | insulin-like growth factor 2 | -0.0183324 |
| CRYBG1 | crystallin beta-gamma domain containing 1 | -0.0182989 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | -0.0182895 |
| MYO1D | myosin ID | -0.01815 |
| RPS16 | ribosomal protein S16 | -0.0180527 |
| RPL27A | ribosomal protein L27a | -0.0180264 |
| PABPC4 | poly(A) binding protein, cytoplasmic 4 (inducible form) | -0.0179182 |
| LSR | lipolysis stimulated lipoprotein receptor | -0.0177821 |
| RPS24 | ribosomal protein S24 | -0.017678 |
| WDR45B | WD repeat domain 45B | -0.0176443 |
