| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | 18β-Glycyrrhetinic acid perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the 18β-Glycyrrhetinic acid_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.368939 |
| B2M | beta-2-microglobulin | 0.169676 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.151897 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.118803 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0999789 |
| LMO7 | LIM domain 7 | 0.0999291 |
| POTEF | POTE ankyrin domain family, member F | 0.0955143 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0915659 |
| RASAL2 | RAS protein activator like 2 | 0.084051 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0801107 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0786862 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0772394 |
| SLC35F3 | solute carrier family 35, member F3 | 0.0724812 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0722821 |
| MTSS1 | metastasis suppressor 1 | 0.0712247 |
| LDHA | lactate dehydrogenase A | 0.0711548 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0694278 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0658371 |
| PLS3 | plastin 3 | 0.0647437 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0628026 |
| PODXL | podocalyxin-like | 0.0615286 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0601451 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0574651 |
| RCOR1 | REST corepressor 1 | 0.056581 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0550399 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0543962 |
| CALB1 | calbindin 1, 28kDa | 0.0536526 |
| MSN | moesin | 0.053006 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0513629 |
| MT2A | metallothionein 2A | 0.0497366 |
| IFITM1 | interferon induced transmembrane protein 1 | 0.0485186 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0481304 |
| CD44 | CD44 molecule (Indian blood group) | 0.0457315 |
| TAGLN2 | transgelin 2 | 0.0457264 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0453215 |
| HLA-A | major histocompatibility complex, class I, A | 0.0448868 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.044506 |
| TPI1 | triosephosphate isomerase 1 | 0.0443307 |
| PCDH1 | protocadherin 1 | 0.0441108 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0436621 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0436033 |
| DIAPH1 | diaphanous-related formin 1 | 0.0435495 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0419425 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0410312 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.040418 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0403008 |
| RNF217 | ring finger protein 217 | 0.0400356 |
| RPS3 | ribosomal protein S3 | 0.0398065 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | 0.0394704 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0388229 |
| SULF2 | sulfatase 2 | 0.0385506 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0375777 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0373156 |
| SIK3 | SIK family kinase 3 | 0.0371732 |
| CDK6 | cyclin-dependent kinase 6 | 0.03708 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0366203 |
| IFI44L | interferon-induced protein 44-like | 0.0362822 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0359098 |
| FTL | ferritin, light polypeptide | 0.0358023 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.035638 |
| RPS17 | ribosomal protein S17 | 0.0355969 |
| HMGA2 | high mobility group AT-hook 2 | 0.0355349 |
| CSTB | cystatin B (stefin B) | 0.0351496 |
| MT1E | metallothionein 1E | 0.0350248 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0345983 |
| EFNA5 | ephrin-A5 | 0.0344177 |
| RPS12 | ribosomal protein S12 | 0.0341989 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0340239 |
| INTS6 | integrator complex subunit 6 | 0.0335961 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0335784 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 0.0334557 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.031762 |
| FLG | filaggrin | 0.0316388 |
| RPS6 | ribosomal protein S6 | 0.0315415 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.0313784 |
| ENO1 | enolase 1, (alpha) | 0.0311679 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0309807 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0305442 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 0.0303738 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0301935 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0301767 |
| LAMC2 | laminin, gamma 2 | 0.0300831 |
| RPL37 | ribosomal protein L37 | 0.0294637 |
| EGFR | epidermal growth factor receptor | 0.0291315 |
| RND3 | Rho family GTPase 3 | 0.0290207 |
| MDK | midkine (neurite growth-promoting factor 2) | 0.028977 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0287948 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0287657 |
| RPL12 | ribosomal protein L12 | 0.0274694 |
| PTK2 | protein tyrosine kinase 2 | 0.0274308 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0273618 |
| HLA-B | major histocompatibility complex, class I, B | 0.0273258 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0273129 |
| HSPG2 | heparan sulfate proteoglycan 2 | 0.0270413 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0268606 |
| TJP1 | tight junction protein 1 | 0.026722 |
| OXSR1 | oxidative stress responsive 1 | 0.026663 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.0265632 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.0264821 |
| STC1 | stanniocalcin 1 | 0.0264438 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.1145 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.092295 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0895721 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0808932 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0746773 |
| CUL4B | cullin 4B | -0.0631645 |
| RBM39 | RNA binding motif protein 39 | -0.0539657 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0509988 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0491751 |
| GOLGA4 | golgin A4 | -0.048663 |
| CANX | calnexin | -0.0484394 |
| MYOF | myoferlin | -0.0483772 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0478329 |
| KIAA1217 | KIAA1217 | -0.0460927 |
| OGA | O-GlcNAcase | -0.0455785 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | -0.0449428 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.044443 |
| TMSB10 | thymosin beta 10 | -0.0436966 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | -0.0414877 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.040984 |
| PLAT | plasminogen activator, tissue | -0.0405229 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0386914 |
| LMNA | lamin A/C | -0.0386458 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0384894 |
| KRT17 | keratin 17, type I | -0.0375453 |
| CLU | clusterin | -0.037446 |
| TMSB4X | thymosin beta 4, X-linked | -0.0366605 |
| PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) | -0.0357522 |
| ANKRD33B | ankyrin repeat domain 33B | -0.0349394 |
| HDLBP | high density lipoprotein binding protein | -0.0339924 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0329804 |
| EMP1 | epithelial membrane protein 1 | -0.0327409 |
| PTMA | prothymosin, alpha | -0.0327071 |
| AHNAK | AHNAK nucleoprotein | -0.0320422 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | -0.0317801 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0310149 |
| HM13 | histocompatibility (minor) 13 | -0.0307691 |
| CALR | calreticulin | -0.0307459 |
| SULF1 | sulfatase 1 | -0.0306152 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0305738 |
| SDC4 | syndecan 4 | -0.0295678 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0291782 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0291049 |
| CFDP1 | craniofacial development protein 1 | -0.0291035 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -0.0289233 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.028624 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0284618 |
| TMEM263 | transmembrane protein 263 | -0.0284425 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.0284199 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0283126 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0280856 |
| NCOA3 | nuclear receptor coactivator 3 | -0.0279863 |
| FOXO1 | forkhead box O1 | -0.0279603 |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 | -0.027652 |
| RPS21 | ribosomal protein S21 | -0.0273516 |
| EFHD2 | EF-hand domain family, member D2 | -0.0269365 |
| PRELID2 | PRELI domain containing 2 | -0.0267146 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0265553 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0264552 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0263539 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0262062 |
| H1-0 | H1.0 linker histone | -0.0257542 |
| ERAP2 | endoplasmic reticulum aminopeptidase 2 | -0.0257406 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0250837 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0246125 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0245829 |
| WDR26 | WD repeat domain 26 | -0.024336 |
| TOP1 | topoisomerase (DNA) I | -0.0242944 |
| NF1 | neurofibromin 1 | -0.0242582 |
| LNPEP | leucyl/cystinyl aminopeptidase | -0.0240343 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0237342 |
| DENND4C | DENN/MADD domain containing 4C | -0.0236052 |
| COG6 | component of oligomeric golgi complex 6 | -0.0235616 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0234867 |
| LIFR | leukemia inhibitory factor receptor alpha | -0.0232655 |
| HYCC2 | hyccin PI4KA lipid kinase complex subunit 2 | -0.0231657 |
| MORF4L2 | mortality factor 4 like 2 | -0.0230732 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0230677 |
| METTL15 | methyltransferase like 15 | -0.0230299 |
| CD99 | CD99 molecule | -0.0229491 |
| RLF | rearranged L-myc fusion | -0.0229431 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0228588 |
| RIN2 | Ras and Rab interactor 2 | -0.0228386 |
| EXOC6B | exocyst complex component 6B | -0.0226163 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0225785 |
| GNAS | GNAS complex locus | -0.0222975 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0222749 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.0222298 |
| VDAC1 | voltage-dependent anion channel 1 | -0.022173 |
| ARFGAP3 | ADP-ribosylation factor GTPase activating protein 3 | -0.022125 |
| IER3 | immediate early response 3 | -0.0221014 |
| PLEKHA1 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 | -0.022094 |
| S100A10 | S100 calcium binding protein A10 | -0.0220874 |
| EHBP1 | EH domain binding protein 1 | -0.0220263 |
| SLC45A4 | solute carrier family 45, member 4 | -0.0219874 |
| HIP1 | huntingtin interacting protein 1 | -0.0219654 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0219553 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0219472 |
| CAVIN1 | caveolae associated protein 1 | -0.0217027 |
| SEC24D | SEC24 family member D | -0.0216178 |