| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | 18β-Glycyrrhetinic acid perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the 18β-Glycyrrhetinic acid_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.139858 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.131371 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.107828 |
| LDHA | lactate dehydrogenase A | 0.0968598 |
| FTL | ferritin, light polypeptide | 0.0948476 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0889691 |
| AREG | amphiregulin | 0.0793984 |
| RPS12 | ribosomal protein S12 | 0.0788474 |
| RPS19 | ribosomal protein S19 | 0.0775138 |
| LMO7 | LIM domain 7 | 0.0771018 |
| RPL12 | ribosomal protein L12 | 0.0739666 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | 0.0688815 |
| RPS3 | ribosomal protein S3 | 0.0656602 |
| RPL9 | ribosomal protein L9 | 0.0651318 |
| RPL23 | ribosomal protein L23 | 0.0593361 |
| TXNIP | thioredoxin interacting protein | 0.0554674 |
| B2M | beta-2-microglobulin | 0.0553467 |
| RPL11 | ribosomal protein L11 | 0.0553092 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0531824 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0523119 |
| MYO1E | myosin IE | 0.05123 |
| RPL18 | ribosomal protein L18 | 0.0502307 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0487067 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | 0.0483006 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.0475019 |
| FAT1 | FAT atypical cadherin 1 | 0.0466951 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.046344 |
| RPL37 | ribosomal protein L37 | 0.0448943 |
| RPL37A | ribosomal protein L37a | 0.0447662 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0446029 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0435069 |
| RPL26 | ribosomal protein L26 | 0.0433354 |
| RPL31 | ribosomal protein L31 | 0.0433083 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0406052 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0402831 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0393448 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0392114 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0388376 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0383752 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0382575 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0375974 |
| RPL7 | ribosomal protein L7 | 0.0372184 |
| MARCHF3 | membrane associated ring-CH-type finger 3 | 0.0370427 |
| TMSB10 | thymosin beta 10 | 0.0362682 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.036258 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 0.0354966 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0353263 |
| RPL36 | ribosomal protein L36 | 0.0346506 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0345738 |
| NDRG1 | N-myc downstream regulated 1 | 0.0345081 |
| MUC13 | mucin 13, cell surface associated | 0.0339736 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0337285 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming | 0.0336588 |
| RPL21 | ribosomal protein L21 | 0.0324833 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0315439 |
| VEGFA | vascular endothelial growth factor A | 0.0313866 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0311963 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0305384 |
| MT2A | metallothionein 2A | 0.0303856 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | 0.0303823 |
| CLDN4 | claudin 4 | 0.0295178 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | 0.0286661 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0285007 |
| EZR | ezrin | 0.0284013 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0276958 |
| DPY19L1 | dpy-19-like 1 (C. elegans) | 0.027675 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0275285 |
| RPS17 | ribosomal protein S17 | 0.0274518 |
| RPLP0 | ribosomal protein, large, P0 | 0.0272765 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0267664 |
| BRD2 | bromodomain containing 2 | 0.0267349 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0262039 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0260029 |
| EGFR | epidermal growth factor receptor | 0.025595 |
| ANXA1 | annexin A1 | 0.0255124 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0251727 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0249385 |
| LURAP1L | leucine rich adaptor protein 1-like | 0.0249258 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | 0.024687 |
| HBEGF | heparin-binding EGF-like growth factor | 0.0245855 |
| RPS27 | ribosomal protein S27 | 0.0244195 |
| PPP4R2 | protein phosphatase 4, regulatory subunit 2 | 0.0242955 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0241309 |
| CLCN3 | chloride channel, voltage-sensitive 3 | 0.023994 |
| RPS4X | ribosomal protein S4, X-linked | 0.0235199 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.0227321 |
| TRIB1 | tribbles pseudokinase 1 | 0.0225451 |
| LIMA1 | LIM domain and actin binding 1 | 0.0225283 |
| HLA-A | major histocompatibility complex, class I, A | 0.0224149 |
| PGK1 | phosphoglycerate kinase 1 | 0.0223152 |
| RPS14 | ribosomal protein S14 | 0.0223092 |
| SVIL | supervillin | 0.021982 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0219033 |
| RNF145 | ring finger protein 145 | 0.0217934 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.0217577 |
| RPL30 | ribosomal protein L30 | 0.0217452 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0217252 |
| RPS2 | ribosomal protein S2 | 0.0217176 |
| EMP1 | epithelial membrane protein 1 | 0.0215014 |
| RPS26 | ribosomal protein S26 | 0.021427 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NPSR1 | neuropeptide S receptor 1 | -0.203657 |
| PTMA | prothymosin, alpha | -0.173192 |
| ANXA2 | annexin A2 | -0.112379 |
| KRT18 | keratin 18, type I | -0.0947089 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0886408 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0869937 |
| KRT8 | keratin 8, type II | -0.0866216 |
| AHNAK | AHNAK nucleoprotein | -0.0812639 |
| ACTG1 | actin gamma 1 | -0.0779186 |
| S100A6 | S100 calcium binding protein A6 | -0.0703479 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0618493 |
| FERMT1 | fermitin family member 1 | -0.0607863 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0561565 |
| GPHN | gephyrin | -0.0557038 |
| DENND1A | DENN/MADD domain containing 1A | -0.0549452 |
| ONECUT3 | one cut homeobox 3 | -0.0541995 |
| SBF2 | SET binding factor 2 | -0.0539486 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0530241 |
| RPL34 | ribosomal protein L34 | -0.0527291 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0512067 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0510894 |
| NFIA | nuclear factor I/A | -0.050683 |
| HMGB1 | high mobility group box 1 | -0.049961 |
| CANX | calnexin | -0.0491883 |
| H1-0 | H1.0 linker histone | -0.0480182 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0477344 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | -0.0473839 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0471248 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0461263 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0459168 |
| MSI2 | musashi RNA-binding protein 2 | -0.0455121 |
| PRSS3 | protease, serine, 3 | -0.0452834 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0444379 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0439641 |
| DSG2 | desmoglein 2 | -0.0438551 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0424918 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0416558 |
| SAMD5 | sterile alpha motif domain containing 5 | -0.0414467 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0412803 |
| TPM4 | tropomyosin 4 | -0.041052 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0405255 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0403478 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0401266 |
| MYO1D | myosin ID | -0.0399038 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0398473 |
| FLNB | filamin B, beta | -0.0395494 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0394452 |
| TNS4 | tensin 4 | -0.0393363 |
| ACTN4 | actinin, alpha 4 | -0.0388387 |
| GOLGA4 | golgin A4 | -0.0385791 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0385225 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0382873 |
| MAP4 | microtubule-associated protein 4 | -0.0380379 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.0375107 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0370647 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0369873 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0369706 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0365219 |
| BAZ2B | bromodomain adjacent to zinc finger domain, 2B | -0.0363548 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0362821 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.035851 |
| GREB1L | growth regulation by estrogen in breast cancer-like | -0.0356739 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0355353 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0353517 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0352373 |
| AGR2 | anterior gradient 2 | -0.0350456 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.0346213 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0343705 |
| PIGR | polymeric immunoglobulin receptor | -0.0341778 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0340723 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0340705 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0334991 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0332714 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0331504 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0331422 |
| RIN2 | Ras and Rab interactor 2 | -0.0323108 |
| OGA | O-GlcNAcase | -0.032087 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | -0.0320443 |
| RBM39 | RNA binding motif protein 39 | -0.0320381 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.031993 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0314048 |
| FRMD5 | FERM domain containing 5 | -0.0313046 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.0312162 |
| RREB1 | ras responsive element binding protein 1 | -0.0309272 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0307471 |
| DLGAP1 | discs, large (Drosophila) homolog-associated protein 1 | -0.0307251 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | -0.0306778 |
| VCL | vinculin | -0.0306543 |
| PRELID2 | PRELI domain containing 2 | -0.0305188 |
| CCND1 | cyclin D1 | -0.0304303 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -0.0303036 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0302277 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | -0.0301295 |
| CD2AP | CD2-associated protein | -0.0301293 |
| EHBP1 | EH domain binding protein 1 | -0.029866 |
| EXOC4 | exocyst complex component 4 | -0.0295106 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0293746 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.029254 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0292367 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0292149 |
