| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | 18β-Glycyrrhetinic acid perturbation in LoVo cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the 18β-Glycyrrhetinic acid_LoVo drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.156648 |
| RPS12 | ribosomal protein S12 | 0.149444 |
| LDHA | lactate dehydrogenase A | 0.102237 |
| RPL23 | ribosomal protein L23 | 0.0940282 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0877781 |
| RACK1 | receptor for activated C kinase 1 | 0.0783574 |
| RPS3 | ribosomal protein S3 | 0.0740234 |
| RPS17 | ribosomal protein S17 | 0.0731208 |
| RPL12 | ribosomal protein L12 | 0.0678949 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0659862 |
| RPL37A | ribosomal protein L37a | 0.0588805 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0552904 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0550941 |
| ENO1 | enolase 1, (alpha) | 0.0527018 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0518674 |
| RPS19 | ribosomal protein S19 | 0.0509764 |
| RPL26 | ribosomal protein L26 | 0.0505406 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0480093 |
| RPL9 | ribosomal protein L9 | 0.0472119 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0470544 |
| PGK1 | phosphoglycerate kinase 1 | 0.0460105 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0448466 |
| INTS6 | integrator complex subunit 6 | 0.0441223 |
| RPL18 | ribosomal protein L18 | 0.0440018 |
| EZR | ezrin | 0.043713 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0436659 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0436058 |
| ASPH | aspartate beta-hydroxylase | 0.0433255 |
| S100P | S100 calcium binding protein P | 0.0426123 |
| FAT1 | FAT atypical cadherin 1 | 0.0422333 |
| RPL37 | ribosomal protein L37 | 0.042121 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0405951 |
| RPL11 | ribosomal protein L11 | 0.0402875 |
| MT2A | metallothionein 2A | 0.0402788 |
| RPLP0 | ribosomal protein, large, P0 | 0.0390934 |
| POTEF | POTE ankyrin domain family, member F | 0.0389732 |
| RPL30 | ribosomal protein L30 | 0.0389206 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0388571 |
| RPL36 | ribosomal protein L36 | 0.0381821 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0370194 |
| HLA-A | major histocompatibility complex, class I, A | 0.0367008 |
| RPL4 | ribosomal protein L4 | 0.0356236 |
| TPI1 | triosephosphate isomerase 1 | 0.0335673 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0321644 |
| MUC13 | mucin 13, cell surface associated | 0.0294851 |
| RPS14 | ribosomal protein S14 | 0.0291879 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.028858 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0286425 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.028211 |
| RPL31 | ribosomal protein L31 | 0.0277509 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0277423 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0274588 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0269058 |
| RPL7 | ribosomal protein L7 | 0.0265222 |
| KRT18 | keratin 18, type I | 0.026397 |
| RPS4X | ribosomal protein S4, X-linked | 0.0263661 |
| EPCAM | epithelial cell adhesion molecule | 0.0246675 |
| PLK2 | polo-like kinase 2 | 0.0245843 |
| TUBB4B | tubulin, beta 4B class IVb | 0.0241652 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0234078 |
| LRRC23 | leucine rich repeat containing 23 | 0.0233805 |
| EFNB2 | ephrin-B2 | 0.023054 |
| DSPP | dentin sialophosphoprotein | 0.0230411 |
| FTL | ferritin, light polypeptide | 0.0224649 |
| IFITM3 | interferon induced transmembrane protein 3 | 0.0221544 |
| KLF6 | Kruppel-like factor 6 | 0.0219031 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0218071 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.0217674 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0216079 |
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) | 0.0215361 |
| PRDX1 | peroxiredoxin 1 | 0.0208243 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0207433 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.020606 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0205744 |
| SERINC5 | serine incorporator 5 | 0.0199803 |
| TES | testin LIM domain protein | 0.0197016 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | 0.0190828 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | 0.0185507 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.0184405 |
| TC2N | tandem C2 domains, nuclear | 0.0179601 |
| RPS5 | ribosomal protein S5 | 0.017947 |
| TAF7 | TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa | 0.0177673 |
| SKP1 | S-phase kinase-associated protein 1 | 0.0177328 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0174553 |
| PDZD8 | PDZ domain containing 8 | 0.0174186 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.017008 |
| POMP | proteasome maturation protein | 0.0169986 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0168555 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0167853 |
| LAMB3 | laminin, beta 3 | 0.0164212 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0163853 |
| HOMER1 | homer scaffolding protein 1 | 0.0160588 |
| SERINC1 | serine incorporator 1 | 0.0160549 |
| SRSF5 | serine/arginine-rich splicing factor 5 | 0.0159263 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0159079 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0157445 |
| S100A11 | S100 calcium binding protein A11 | 0.0157412 |
| NDRG1 | N-myc downstream regulated 1 | 0.0156977 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0156841 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0156831 |
| Symbol | Name | Standardized Value |
|---|---|---|
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.151194 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.117718 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.117704 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0965167 |
| RIGI | RNA sensor RIG-I | -0.0784487 |
| MSI2 | musashi RNA-binding protein 2 | -0.0780864 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0739422 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.072658 |
| ACTN4 | actinin, alpha 4 | -0.0717427 |
| PTMA | prothymosin, alpha | -0.0692155 |
| MX1 | MX dynamin-like GTPase 1 | -0.0681153 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0666716 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | -0.0606781 |
| PLAC8 | placenta-specific 8 | -0.0586895 |
| PRSS3 | protease, serine, 3 | -0.0573294 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0568976 |
| FOXO1 | forkhead box O1 | -0.0544411 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0532147 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0532002 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.053003 |
| RNF213 | ring finger protein 213 | -0.0527605 |
| CUX1 | cut-like homeobox 1 | -0.0526067 |
| RBM25 | RNA binding motif protein 25 | -0.0525871 |
| ITGA6 | integrin, alpha 6 | -0.0510626 |
| RHPN2 | rhophilin, Rho GTPase binding protein 2 | -0.0507158 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | -0.0505108 |
| ANXA11 | annexin A11 | -0.0498589 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0493461 |
| SETD5 | SET domain containing 5 | -0.049004 |
| TCF12 | transcription factor 12 | -0.048911 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0488679 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.048607 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0470601 |
| FGD4 | FYVE, RhoGEF and PH domain containing 4 | -0.0468805 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0466731 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0466434 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0460637 |
| JMJD1C | jumonji domain containing 1C | -0.0454061 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0450333 |
| RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 | -0.0433765 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0432468 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0424109 |
| NF1 | neurofibromin 1 | -0.0423882 |
| VCL | vinculin | -0.0423153 |
| FLNB | filamin B, beta | -0.0420573 |
| MX2 | MX dynamin-like GTPase 2 | -0.04205 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0418312 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0416922 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0413527 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.041345 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0409483 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.0407666 |
| PLSCR1 | phospholipid scramblase 1 | -0.0403678 |
| RPL34 | ribosomal protein L34 | -0.0399688 |
| WWC1 | WW and C2 domain containing 1 | -0.0398357 |
| RAD51B | RAD51 paralog B | -0.0395954 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0392657 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0388549 |
| CDK13 | cyclin-dependent kinase 13 | -0.0384785 |
| TRIM2 | tripartite motif containing 2 | -0.0383797 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0382033 |
| COG5 | component of oligomeric golgi complex 5 | -0.0379601 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0377085 |
| DSG3 | desmoglein 3 | -0.0367555 |
| RPS21 | ribosomal protein S21 | -0.0365697 |
| AOPEP | aminopeptidase O (putative) | -0.0362354 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0360787 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0359417 |
| LAMA4 | laminin, alpha 4 | -0.0357924 |
| FRMD5 | FERM domain containing 5 | -0.0357014 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0355966 |
| P3H2 | prolyl 3-hydroxylase 2 | -0.0352931 |
| MCU | mitochondrial calcium uniporter | -0.0351634 |
| TNRC18 | trinucleotide repeat containing 18 | -0.0350865 |
| CALU | calumenin | -0.0348977 |
| UBE2D2 | ubiquitin-conjugating enzyme E2D 2 | -0.0348943 |
| ETV6 | ets variant 6 | -0.0344523 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0342522 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | -0.03405 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | -0.0340319 |
| RPS13 | ribosomal protein S13 | -0.03401 |
| MAP4 | microtubule-associated protein 4 | -0.033993 |
| RPL36A | ribosomal protein L36a | -0.0339473 |
| TMCC1 | transmembrane and coiled-coil domain family 1 | -0.0337498 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0337288 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0337111 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0336965 |
| PDE8A | phosphodiesterase 8A | -0.0336864 |
| SCAF11 | SR-related CTD-associated factor 11 | -0.0336596 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0334173 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0333728 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0331937 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0331494 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0329377 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.032703 |
| SRPK2 | SRSF protein kinase 2 | -0.0325286 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.0324513 |
| MPRIP | myosin phosphatase Rho interacting protein | -0.0323922 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0322519 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | -0.0317792 |
