| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | 18β-Glycyrrhetinic acid perturbation in NCI-H1573 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the 18β-Glycyrrhetinic acid_NCI-H1573 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | 0.153825 |
| SLTM | SAFB-like, transcription modulator | 0.104042 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.102314 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0981242 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0979614 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0917795 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0875586 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0808833 |
| GRAMD1B | GRAM domain containing 1B | 0.0766498 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0689212 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0686799 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0663242 |
| LDHA | lactate dehydrogenase A | 0.0663186 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | 0.0661256 |
| SEC61G | Sec61 gamma subunit | 0.0594825 |
| NSUN6 | NOP2/Sun domain family, member 6 | 0.0594357 |
| STC1 | stanniocalcin 1 | 0.055999 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0549588 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0547942 |
| TES | testin LIM domain protein | 0.0544688 |
| AREG | amphiregulin | 0.0540392 |
| ENO1 | enolase 1, (alpha) | 0.0506492 |
| LAMA4 | laminin, alpha 4 | 0.0496298 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0491742 |
| TOP1 | topoisomerase (DNA) I | 0.0476739 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.043614 |
| RPS3 | ribosomal protein S3 | 0.0426135 |
| PM20D1 | peptidase M20 domain containing 1 | 0.0422612 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0420902 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0420227 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0415048 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0410607 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0397525 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0393359 |
| RPL23 | ribosomal protein L23 | 0.0370759 |
| CIB1 | calcium and integrin binding 1 (calmyrin) | 0.0355951 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0352747 |
| BMP6 | bone morphogenetic protein 6 | 0.0349427 |
| RPL12 | ribosomal protein L12 | 0.0347713 |
| SIK3 | SIK family kinase 3 | 0.0344759 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0342483 |
| FAM13A | family with sequence similarity 13, member A | 0.0338472 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0333542 |
| EGR1 | early growth response 1 | 0.0317985 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0317539 |
| C15ORF48 | chromosome 15 open reading frame 48 | 0.0316013 |
| IRS2 | insulin receptor substrate 2 | 0.0315722 |
| LMO7 | LIM domain 7 | 0.0299872 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) | 0.0297749 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0287064 |
| YBX3 | Y box binding protein 3 | 0.0279863 |
| RPLP0 | ribosomal protein, large, P0 | 0.0277567 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0272063 |
| HOMER1 | homer scaffolding protein 1 | 0.0271132 |
| MYO1E | myosin IE | 0.026935 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0257391 |
| RPS19 | ribosomal protein S19 | 0.0256958 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0256666 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0250952 |
| TNFAIP8 | tumor necrosis factor, alpha-induced protein 8 | 0.0244902 |
| S100P | S100 calcium binding protein P | 0.0242479 |
| SMYD3 | SET and MYND domain containing 3 | 0.0240088 |
| EZR | ezrin | 0.0237877 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0237129 |
| OXSR1 | oxidative stress responsive 1 | 0.0235863 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0231684 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0230443 |
| TJP1 | tight junction protein 1 | 0.0227343 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0227108 |
| FAM110C | family with sequence similarity 110, member C | 0.0223797 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0221117 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0219645 |
| RPS12 | ribosomal protein S12 | 0.0217597 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0217396 |
| TPI1 | triosephosphate isomerase 1 | 0.0216969 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0215721 |
| SON | SON DNA binding protein | 0.0215402 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0213259 |
| RPS4X | ribosomal protein S4, X-linked | 0.0211401 |
| RNF149 | ring finger protein 149 | 0.0208922 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | 0.0208614 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0207597 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0206279 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0205298 |
| NTN4 | netrin 4 | 0.0205271 |
| ATP13A3 | ATPase type 13A3 | 0.020092 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0199429 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0198181 |
| PYGL | phosphorylase, glycogen, liver | 0.0194745 |
| BLZF1 | basic leucine zipper nuclear factor 1 | 0.0194103 |
| MPP2 | membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) | 0.0193683 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0193457 |
| FTL | ferritin, light polypeptide | 0.0193033 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0192386 |
| MSN | moesin | 0.0190661 |
| JUN | jun proto-oncogene | 0.0190303 |
| PCBP2 | poly(rC) binding protein 2 | 0.0189829 |
| DAPP1 | dual adaptor of phosphotyrosine and 3-phosphoinositides | 0.0189238 |
| SIPA1L2 | signal-induced proliferation-associated 1 like 2 | 0.0189041 |
| ATP11A | ATPase, class VI, type 11A | 0.01886 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TXNRD1 | thioredoxin reductase 1 | -0.127795 |
| EGFR | epidermal growth factor receptor | -0.12297 |
| LRP1B | low density lipoprotein receptor-related protein 1B | -0.0878917 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0860701 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0850346 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0830422 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.082736 |
| PTMA | prothymosin, alpha | -0.0760195 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.0759932 |
| ACTG1 | actin gamma 1 | -0.069047 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.0684549 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0672782 |
| ASPH | aspartate beta-hydroxylase | -0.0610688 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0581084 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0547016 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0528837 |
| TMSB10 | thymosin beta 10 | -0.0505272 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0503561 |
| USP34 | ubiquitin specific peptidase 34 | -0.050048 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0483045 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.047829 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0468382 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0464025 |
| HDLBP | high density lipoprotein binding protein | -0.0453966 |
| WASF2 | WAS protein family, member 2 | -0.0453822 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.045008 |
| KRT8 | keratin 8, type II | -0.0440032 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0438274 |
| KRT7 | keratin 7, type II | -0.0432453 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.0423353 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0420631 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0419676 |
| CANX | calnexin | -0.0417317 |
| ADAR | adenosine deaminase, RNA-specific | -0.0417142 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | -0.0416004 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0413379 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0407337 |
| GPC6 | glypican 6 | -0.0395558 |
| KCMF1 | potassium channel modulatory factor 1 | -0.0391574 |
| RAB10 | RAB10, member RAS oncogene family | -0.038578 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0383622 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0383123 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0377082 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0365866 |
| RPS25 | ribosomal protein S25 | -0.0362616 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0360478 |
| TRAF3 | TNF receptor-associated factor 3 | -0.0354754 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0351668 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0351546 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.035073 |
| YEATS2 | YEATS domain containing 2 | -0.0345992 |
| FNIP1 | folliculin interacting protein 1 | -0.034494 |
| NDRG1 | N-myc downstream regulated 1 | -0.0344387 |
| CCND1 | cyclin D1 | -0.0341322 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0340604 |
| AGR2 | anterior gradient 2 | -0.0337692 |
| TNS3 | tensin 3 | -0.0337575 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.03327 |
| SPIRE1 | spire-type actin nucleation factor 1 | -0.0331751 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | -0.0329225 |
| TBC1D22A | TBC1 domain family, member 22A | -0.032762 |
| MYO1D | myosin ID | -0.0326488 |
| MCL1 | myeloid cell leukemia 1 | -0.0320844 |
| RPL35A | ribosomal protein L35a | -0.031998 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -0.0317528 |
| CTTN | cortactin | -0.0316488 |
| CST3 | cystatin C | -0.0313863 |
| HM13 | histocompatibility (minor) 13 | -0.0311659 |
| TMEM165 | transmembrane protein 165 | -0.0310936 |
| RIN2 | Ras and Rab interactor 2 | -0.0310726 |
| RPS23 | ribosomal protein S23 | -0.0309153 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0308702 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | -0.0305859 |
| MKI67 | marker of proliferation Ki-67 | -0.0302892 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0299427 |
| CES1 | carboxylesterase 1 | -0.0299105 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0296683 |
| UBAC2 | UBA domain containing 2 | -0.0295938 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | -0.0295513 |
| PKM | pyruvate kinase, muscle | -0.0294378 |
| S100A10 | S100 calcium binding protein A10 | -0.0293771 |
| SETD5 | SET domain containing 5 | -0.0292979 |
| CUX1 | cut-like homeobox 1 | -0.0289103 |
| ABCC1 | ATP-binding cassette, sub-family C (CFTR/MRP), member 1 | -0.0288579 |
| GOLGB1 | golgin B1 | -0.0287567 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0284175 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0284173 |
| AHNAK | AHNAK nucleoprotein | -0.0283681 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0282319 |
| CCNL1 | cyclin L1 | -0.0279557 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | -0.0278836 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0276324 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0275766 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0273894 |
| PRKCA | protein kinase C, alpha | -0.0271798 |
| TMOD3 | tropomodulin 3 (ubiquitous) | -0.0271562 |
| PDE8A | phosphodiesterase 8A | -0.0269615 |
| VOPP1 | vesicular, overexpressed in cancer, prosurvival protein 1 | -0.0268609 |
| SBF2 | SET binding factor 2 | -0.0266438 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.0261092 |
