| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | 18β-Glycyrrhetinic acid perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the 18β-Glycyrrhetinic acid_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.154934 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.113292 |
| PCBP2 | poly(rC) binding protein 2 | 0.0997085 |
| NDRG1 | N-myc downstream regulated 1 | 0.0974006 |
| SMAD3 | SMAD family member 3 | 0.0883787 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0752278 |
| MT2A | metallothionein 2A | 0.0674326 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0660636 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0642328 |
| ANGPTL4 | angiopoietin-like 4 | 0.0639318 |
| NAV2 | neuron navigator 2 | 0.0615789 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0600898 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0555003 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0503047 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0501668 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0494611 |
| RUNX1 | runt-related transcription factor 1 | 0.0453024 |
| B2M | beta-2-microglobulin | 0.0447806 |
| IFI44L | interferon-induced protein 44-like | 0.0425301 |
| ENO1 | enolase 1, (alpha) | 0.0418161 |
| LDHA | lactate dehydrogenase A | 0.0417666 |
| RPS12 | ribosomal protein S12 | 0.0373933 |
| ECE1 | endothelin converting enzyme 1 | 0.0373816 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0373085 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0372678 |
| FTL | ferritin, light polypeptide | 0.0371915 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.0368527 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.03681 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0361981 |
| RPS17 | ribosomal protein S17 | 0.0359455 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0355352 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0345379 |
| RPL23 | ribosomal protein L23 | 0.0340389 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0339982 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.0338965 |
| FLNB | filamin B, beta | 0.033562 |
| EFNA5 | ephrin-A5 | 0.0331478 |
| PARP8 | poly (ADP-ribose) polymerase family, member 8 | 0.0323444 |
| RARB | retinoic acid receptor, beta | 0.0322642 |
| FAM13A | family with sequence similarity 13, member A | 0.0322171 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0318513 |
| RPS19 | ribosomal protein S19 | 0.0314643 |
| RPL12 | ribosomal protein L12 | 0.0313183 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0312075 |
| RPL11 | ribosomal protein L11 | 0.0308566 |
| TGM2 | transglutaminase 2 | 0.0303663 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0299547 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0295929 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0283976 |
| INTS6 | integrator complex subunit 6 | 0.0281203 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0281175 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0279114 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0272858 |
| LOX | lysyl oxidase | 0.027115 |
| AHR | aryl hydrocarbon receptor | 0.0268668 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0268162 |
| PRELID2 | PRELI domain containing 2 | 0.0266557 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0263674 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0263149 |
| RACK1 | receptor for activated C kinase 1 | 0.0261468 |
| NOTCH2 | notch 2 | 0.0254646 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0249782 |
| MED13L | mediator complex subunit 13-like | 0.0249262 |
| RAD51B | RAD51 paralog B | 0.0249183 |
| FBXO32 | F-box protein 32 | 0.024823 |
| MSN | moesin | 0.024608 |
| LOXL2 | lysyl oxidase-like 2 | 0.0243625 |
| PLIN2 | perilipin 2 | 0.0241925 |
| NEBL | nebulette | 0.0241385 |
| RAI1 | retinoic acid induced 1 | 0.0235804 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0234941 |
| ZNRF1 | zinc and ring finger 1, E3 ubiquitin protein ligase | 0.0231604 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.023095 |
| VEGFA | vascular endothelial growth factor A | 0.0230125 |
| ANXA1 | annexin A1 | 0.0228672 |
| ZNF292 | zinc finger protein 292 | 0.0225348 |
| YBX1 | Y box binding protein 1 | 0.0224362 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0223838 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0220595 |
| YBX3 | Y box binding protein 3 | 0.0219957 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0219011 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0215472 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0215077 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0214958 |
| SQSTM1 | sequestosome 1 | 0.0214751 |
| SMYD3 | SET and MYND domain containing 3 | 0.0214676 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0212749 |
| ZNF638 | zinc finger protein 638 | 0.0212483 |
| SON | SON DNA binding protein | 0.0211321 |
| PTK2 | protein tyrosine kinase 2 | 0.0208717 |
| RPS3 | ribosomal protein S3 | 0.0208655 |
| SKAP2 | src kinase associated phosphoprotein 2 | 0.0208638 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | 0.0206862 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0205989 |
| GALNT1 | polypeptide N-acetylgalactosaminyltransferase 1 | 0.0204463 |
| SIK3 | SIK family kinase 3 | 0.0204114 |
| RPS24 | ribosomal protein S24 | 0.0203246 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0202528 |
| TGFBR1 | transforming growth factor, beta receptor 1 | 0.020022 |
| DYNC2H1 | dynein, cytoplasmic 2, heavy chain 1 | 0.0198573 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.178873 |
| FN1 | fibronectin 1 | -0.151555 |
| OSMR | oncostatin M receptor | -0.115785 |
| NRG1 | neuregulin 1 | -0.105205 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.102123 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0983761 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0965006 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0841713 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | -0.0812406 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0812272 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0788328 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0786947 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0786398 |
| CDH13 | cadherin 13 | -0.0743052 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0738419 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0720552 |
| GOLGA4 | golgin A4 | -0.0708742 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0697627 |
| RBM39 | RNA binding motif protein 39 | -0.0677293 |
| STC1 | stanniocalcin 1 | -0.0654181 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0634422 |
| GLCCI1 | glucocorticoid induced 1 | -0.0624285 |
| PTMA | prothymosin, alpha | -0.0560172 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0558232 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0548346 |
| TMSB10 | thymosin beta 10 | -0.0522573 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0520158 |
| VRK2 | vaccinia related kinase 2 | -0.051459 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0514269 |
| MEF2A | myocyte enhancer factor 2A | -0.0510936 |
| PID1 | phosphotyrosine interaction domain containing 1 | -0.0509464 |
| CANX | calnexin | -0.0506496 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0503986 |
| HM13 | histocompatibility (minor) 13 | -0.0490411 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | -0.0477296 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0472225 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.0471974 |
| CD44 | CD44 molecule (Indian blood group) | -0.0470968 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0449383 |
| CLIC4 | chloride intracellular channel 4 | -0.0444771 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0438397 |
| SNX9 | sorting nexin 9 | -0.0436065 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | -0.0435617 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0433363 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | -0.0430396 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0414332 |
| AOPEP | aminopeptidase O (putative) | -0.0408178 |
| TPM4 | tropomyosin 4 | -0.0406433 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0403101 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0400932 |
| NF1 | neurofibromin 1 | -0.0399966 |
| RAB27B | RAB27B, member RAS oncogene family | -0.0395058 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0393396 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0391494 |
| ETV6 | ets variant 6 | -0.0386967 |
| PRRX1 | paired related homeobox 1 | -0.0386835 |
| USP34 | ubiquitin specific peptidase 34 | -0.0381569 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0379645 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | -0.0379374 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.03763 |
| NRP1 | neuropilin 1 | -0.037484 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0370599 |
| CUX1 | cut-like homeobox 1 | -0.036585 |
| DNER | delta/notch-like EGF repeat containing | -0.0365185 |
| COL12A1 | collagen, type XII, alpha 1 | -0.0364634 |
| DENND4A | DENN/MADD domain containing 4A | -0.0361968 |
| S100A6 | S100 calcium binding protein A6 | -0.0358915 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.035658 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.03499 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0346906 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0345758 |
| CLMP | CXADR-like membrane protein | -0.0345364 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0339975 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0339136 |
| NAV3 | neuron navigator 3 | -0.0338773 |
| CALU | calumenin | -0.0338607 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.0335909 |
| BPTF | bromodomain PHD finger transcription factor | -0.0335509 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0332466 |
| ABCA6 | ATP-binding cassette, sub-family A (ABC1), member 6 | -0.0331831 |
| VIM | vimentin | -0.033077 |
| BMERB1 | bMERB domain containing 1 | -0.0330541 |
| HEG1 | heart development protein with EGF-like domains 1 | -0.0329243 |
| HDLBP | high density lipoprotein binding protein | -0.0329096 |
| IER3 | immediate early response 3 | -0.0327991 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0327258 |
| INSIG1 | insulin induced gene 1 | -0.0327173 |
| TMEM165 | transmembrane protein 165 | -0.0325324 |
| NBEAL1 | neurobeachin-like 1 | -0.0322099 |
| MAP4 | microtubule-associated protein 4 | -0.0322039 |
| ADAMTS12 | ADAM metallopeptidase with thrombospondin type 1 motif, 12 | -0.0319535 |
| ANXA10 | annexin A10 | -0.0312924 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | -0.031269 |
| MTSS1 | metastasis suppressor 1 | -0.0311013 |
| RSU1 | Ras suppressor protein 1 | -0.0310263 |
| KYNU | kynureninase | -0.0308625 |
| NPAS2 | neuronal PAS domain protein 2 | -0.030645 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0306231 |
| TMSB4X | thymosin beta 4, X-linked | -0.0306161 |
| FRMD4A | FERM domain containing 4A | -0.0305549 |
