| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | 18β-Glycyrrhetinic acid perturbation in NCI-H2030 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the 18β-Glycyrrhetinic acid_NCI-H2030 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | 0.321129 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.125054 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.108641 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0973449 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0873206 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.079101 |
| VIM | vimentin | 0.0747236 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0705778 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0682266 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0666347 |
| HLA-A | major histocompatibility complex, class I, A | 0.0662849 |
| HLA-B | major histocompatibility complex, class I, B | 0.0654391 |
| LDHA | lactate dehydrogenase A | 0.064261 |
| STC1 | stanniocalcin 1 | 0.0642146 |
| C15ORF48 | chromosome 15 open reading frame 48 | 0.060164 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0601356 |
| NDRG1 | N-myc downstream regulated 1 | 0.0588075 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0584851 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0563536 |
| PYGL | phosphorylase, glycogen, liver | 0.0553624 |
| FAM107B | family with sequence similarity 107, member B | 0.054357 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.05248 |
| CMIP | c-Maf inducing protein | 0.051774 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0514364 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0511519 |
| ANGPTL4 | angiopoietin-like 4 | 0.0508995 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0506255 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0493191 |
| IGF2 | insulin-like growth factor 2 | 0.045931 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0452948 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0444872 |
| IL6 | interleukin 6 | 0.0436348 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0389359 |
| OSMR | oncostatin M receptor | 0.0369483 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0366141 |
| GLIS3 | GLIS family zinc finger 3 | 0.0361576 |
| FLNB | filamin B, beta | 0.0360511 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0357178 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0353712 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0353527 |
| S100A6 | S100 calcium binding protein A6 | 0.034688 |
| EGR1 | early growth response 1 | 0.0339503 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0335437 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0331975 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0324928 |
| B2M | beta-2-microglobulin | 0.032124 |
| IGFBP4 | insulin-like growth factor binding protein 4 | 0.0315078 |
| ATXN1 | ataxin 1 | 0.031423 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | 0.0312355 |
| ASPH | aspartate beta-hydroxylase | 0.0303757 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0296292 |
| SVIL | supervillin | 0.0296075 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0292477 |
| FMNL2 | formin-like 2 | 0.0287012 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0286789 |
| PRDX1 | peroxiredoxin 1 | 0.0286165 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0283689 |
| NF1 | neurofibromin 1 | 0.0280952 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | 0.0278228 |
| EGFR | epidermal growth factor receptor | 0.027613 |
| NAV3 | neuron navigator 3 | 0.0273934 |
| POTEF | POTE ankyrin domain family, member F | 0.026316 |
| KYNU | kynureninase | 0.0262146 |
| MCL1 | myeloid cell leukemia 1 | 0.0260051 |
| DSE | dermatan sulfate epimerase | 0.0256326 |
| MT1X | metallothionein 1X | 0.0255548 |
| EXOC6B | exocyst complex component 6B | 0.0252365 |
| CUX1 | cut-like homeobox 1 | 0.0248765 |
| CD44 | CD44 molecule (Indian blood group) | 0.0246409 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0245257 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0242797 |
| ACTN1 | actinin, alpha 1 | 0.0241281 |
| NBEAL1 | neurobeachin-like 1 | 0.0241227 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0239945 |
| TNFAIP8 | tumor necrosis factor, alpha-induced protein 8 | 0.0231522 |
| TTC28 | tetratricopeptide repeat domain 28 | 0.0230824 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0230217 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.023019 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0229767 |
| RAB2A | RAB2A, member RAS oncogene family | 0.0227364 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | 0.0226691 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0223371 |
| MYADM | myeloid-associated differentiation marker | 0.0221716 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0221392 |
| TBC1D5 | TBC1 domain family, member 5 | 0.022021 |
| FOXP1 | forkhead box P1 | 0.0217153 |
| UBXN4 | UBX domain protein 4 | 0.0216519 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0215794 |
| MAP1B | microtubule-associated protein 1B | 0.0214466 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | 0.0212782 |
| TCF12 | transcription factor 12 | 0.0212762 |
| ANO6 | anoctamin 6 | 0.0211099 |
| MSN | moesin | 0.0210803 |
| INHBA | inhibin, beta A | 0.0208389 |
| PATJ | PATJ crumbs cell polarity complex component | 0.0207916 |
| USP34 | ubiquitin specific peptidase 34 | 0.0206087 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0205145 |
| CDCP1 | CUB domain containing protein 1 | 0.0204575 |
| NEBL | nebulette | 0.0202737 |
| TPI1 | triosephosphate isomerase 1 | 0.0198967 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FTL | ferritin, light polypeptide | -0.18715 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.174123 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.109071 |
| PTMA | prothymosin, alpha | -0.0856869 |
| RPL23 | ribosomal protein L23 | -0.0706045 |
| RPLP1 | ribosomal protein, large, P1 | -0.0660276 |
| TMSB10 | thymosin beta 10 | -0.0651858 |
| RPL19 | ribosomal protein L19 | -0.0649059 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0623617 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0594602 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0567932 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0566274 |
| USP3 | ubiquitin specific peptidase 3 | -0.0547454 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0517183 |
| RBM39 | RNA binding motif protein 39 | -0.0508808 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0504605 |
| GRAMD1B | GRAM domain containing 1B | -0.0499687 |
| TXNRD1 | thioredoxin reductase 1 | -0.0496435 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0484826 |
| PFDN2 | prefoldin subunit 2 | -0.0478035 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0471331 |
| RTN4 | reticulon 4 | -0.0440976 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0429419 |
| ACTG1 | actin gamma 1 | -0.0425519 |
| KHDC4 | KH domain containing 4, pre-mRNA splicing factor | -0.0419077 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0417496 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | -0.0404043 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0398379 |
| APP | amyloid beta (A4) precursor protein | -0.0373629 |
| RPL8 | ribosomal protein L8 | -0.0372638 |
| YBX1 | Y box binding protein 1 | -0.0370195 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0368545 |
| WDR43 | WD repeat domain 43 | -0.0365865 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0360492 |
| RPL5 | ribosomal protein L5 | -0.0359315 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0357684 |
| RPL4 | ribosomal protein L4 | -0.0356369 |
| CYRIB | CYFIP related Rac1 interactor B | -0.0348569 |
| RPS21 | ribosomal protein S21 | -0.0346307 |
| ZNF292 | zinc finger protein 292 | -0.0343108 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.033878 |
| RHEB | Ras homolog enriched in brain | -0.0337745 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0335387 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0334059 |
| NPR2 | natriuretic peptide receptor 2 | -0.0332807 |
| RPL36 | ribosomal protein L36 | -0.0326549 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -0.0325897 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0325358 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0324378 |
| HMGB1 | high mobility group box 1 | -0.0320357 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | -0.031755 |
| CHN1 | chimerin 1 | -0.031687 |
| KIF5B | kinesin family member 5B | -0.0314027 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | -0.0313208 |
| FUS | FUS RNA binding protein | -0.0308765 |
| TPD52 | tumor protein D52 | -0.0308656 |
| TMEM123 | transmembrane protein 123 | -0.030483 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.030468 |
| CANX | calnexin | -0.0304325 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0304046 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0303239 |
| RPL7 | ribosomal protein L7 | -0.0301594 |
| RPS5 | ribosomal protein S5 | -0.0299469 |
| CCT5 | chaperonin containing TCP1, subunit 5 (epsilon) | -0.0298364 |
| WTAP | Wilms tumor 1 associated protein | -0.0297187 |
| RPS20 | ribosomal protein S20 | -0.0294137 |
| MATR3 | matrin 3 | -0.029135 |
| PSMC6 | proteasome (prosome, macropain) 26S subunit, ATPase, 6 | -0.0291268 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | -0.0287471 |
| YBX3 | Y box binding protein 3 | -0.028631 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0285985 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0285753 |
| RPS29 | ribosomal protein S29 | -0.0281564 |
| FGB | fibrinogen beta chain | -0.0276184 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0275997 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0268949 |
| NOP58 | NOP58 ribonucleoprotein | -0.0267686 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.026166 |
| PUM1 | pumilio RNA-binding family member 1 | -0.0261627 |
| ZNF207 | zinc finger protein 207 | -0.0260877 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.026055 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0254341 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0253699 |
| ENAH | enabled homolog (Drosophila) | -0.0253213 |
| LANCL1 | LanC lantibiotic synthetase component C-like 1 (bacterial) | -0.0251782 |
| RPL13A | ribosomal protein L13a | -0.0245934 |
| RPL34 | ribosomal protein L34 | -0.0243679 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0242376 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0242107 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0239233 |
| RNF145 | ring finger protein 145 | -0.0238769 |
| GNAI1 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 | -0.0235675 |
| RPS23 | ribosomal protein S23 | -0.0235489 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | -0.0232777 |
| JAK1 | Janus kinase 1 | -0.0231012 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0230759 |
| ANLN | anillin, actin binding protein | -0.0227999 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.0227841 |
| MTF2 | metal response element binding transcription factor 2 | -0.0226613 |
| ILF2 | interleukin enhancer binding factor 2 | -0.0224198 |
