| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | 18β-Glycyrrhetinic acid perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the 18β-Glycyrrhetinic acid_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ISG15 | ISG15 ubiquitin-like modifier | 0.113278 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0991397 |
| B2M | beta-2-microglobulin | 0.0799172 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.0756027 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0680726 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0674169 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.062399 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0615878 |
| RBM25 | RNA binding motif protein 25 | 0.0604115 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0591826 |
| OGA | O-GlcNAcase | 0.053297 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.052354 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | 0.052012 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0508761 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0508128 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.05077 |
| KYNU | kynureninase | 0.0503345 |
| H3-3B | H3.3 histone B | 0.0502944 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0495721 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0494106 |
| KDM5B | lysine (K)-specific demethylase 5B | 0.0484555 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0478009 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0468905 |
| SLMAP | sarcolemma associated protein | 0.0465551 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0460102 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0453493 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0451662 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0450386 |
| OASL | 2'-5'-oligoadenylate synthetase-like | 0.0441339 |
| WDFY3 | WD repeat and FYVE domain containing 3 | 0.043894 |
| FOXJ3 | forkhead box J3 | 0.043304 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.043277 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0429575 |
| MYOF | myoferlin | 0.0424392 |
| USP8 | ubiquitin specific peptidase 8 | 0.0421653 |
| ATXN1 | ataxin 1 | 0.041864 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.0417642 |
| RTN4 | reticulon 4 | 0.0411121 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | 0.0410181 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0407785 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0400072 |
| ABLIM1 | actin binding LIM protein 1 | 0.0399532 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0393624 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0393577 |
| MATR3 | matrin 3 | 0.039184 |
| PTPRA | protein tyrosine phosphatase, receptor type, A | 0.0384792 |
| RAB8B | RAB8B, member RAS oncogene family | 0.038459 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0384345 |
| SEC24A | SEC24 family member A | 0.0382565 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0382414 |
| VIM | vimentin | 0.0381418 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0381354 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0381128 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0378764 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0378497 |
| FBXL5 | F-box and leucine-rich repeat protein 5 | 0.0372452 |
| VCAN | versican | 0.0370691 |
| TTC17 | tetratricopeptide repeat domain 17 | 0.0370309 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.0367892 |
| CCL5 | chemokine (C-C motif) ligand 5 | 0.0367288 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.036568 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0361013 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0360951 |
| FBXO32 | F-box protein 32 | 0.0355918 |
| CREBRF | CREB3 regulatory factor | 0.035467 |
| FNIP1 | folliculin interacting protein 1 | 0.035324 |
| ENO1 | enolase 1, (alpha) | 0.0348793 |
| STC1 | stanniocalcin 1 | 0.0344468 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0340528 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0336175 |
| HLA-B | major histocompatibility complex, class I, B | 0.0335951 |
| KIF5B | kinesin family member 5B | 0.0333115 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.032927 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0328335 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.0325614 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0324999 |
| INHBA | inhibin, beta A | 0.0324974 |
| VEGFA | vascular endothelial growth factor A | 0.0324015 |
| TJP1 | tight junction protein 1 | 0.0323775 |
| TMSB10 | thymosin beta 10 | 0.0322682 |
| NKTR | natural killer cell triggering receptor | 0.0320104 |
| CAB39 | calcium binding protein 39 | 0.0317657 |
| MAP4K3 | mitogen-activated protein kinase kinase kinase kinase 3 | 0.031727 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.031655 |
| ASPH | aspartate beta-hydroxylase | 0.0316385 |
| PDE8A | phosphodiesterase 8A | 0.0315471 |
| CAMK2D | calcium/calmodulin-dependent protein kinase II delta | 0.0313786 |
| RPS27L | ribosomal protein S27-like | 0.0311757 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0311309 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0309136 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0305727 |
| RLF | rearranged L-myc fusion | 0.030484 |
| EXOC6B | exocyst complex component 6B | 0.0303143 |
| MAPK8 | mitogen-activated protein kinase 8 | 0.0302312 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0301254 |
| JAK1 | Janus kinase 1 | 0.029978 |
| ARB2A | ARB2 cotranscriptional regulator A | 0.0298915 |
| GALNT15 | polypeptide N-acetylgalactosaminyltransferase 15 | 0.0298534 |
| RBM39 | RNA binding motif protein 39 | 0.0298007 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0292924 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.244753 |
| LAMC2 | laminin, gamma 2 | -0.179281 |
| LMO7 | LIM domain 7 | -0.178851 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | -0.166902 |
| GRB10 | growth factor receptor-bound protein 10 | -0.152599 |
| MYO1E | myosin IE | -0.146609 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.146139 |
| ANXA2 | annexin A2 | -0.123468 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.099625 |
| ATOSA | atos homolog A | -0.095141 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0930777 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.090027 |
| LAMB3 | laminin, beta 3 | -0.0849983 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0848306 |
| CMIP | c-Maf inducing protein | -0.0845598 |
| SVIL | supervillin | -0.0738951 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0719606 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0674777 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0662612 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0641177 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0633831 |
| KRT17 | keratin 17, type I | -0.0626471 |
| TC2N | tandem C2 domains, nuclear | -0.0588058 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0555382 |
| MUC16 | mucin 16, cell surface associated | -0.0540708 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | -0.0532144 |
| RESF1 | retroelement silencing factor 1 | -0.0525771 |
| TMCC3 | transmembrane and coiled-coil domain family 3 | -0.0525608 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.0524584 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -0.0522195 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | -0.0515902 |
| ANKRD36C | ankyrin repeat domain 36C | -0.0515262 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0513514 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 | -0.0503926 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0503867 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | -0.0498923 |
| RPS6 | ribosomal protein S6 | -0.0498007 |
| RPL37A | ribosomal protein L37a | -0.0491341 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | -0.0491199 |
| SGMS2 | sphingomyelin synthase 2 | -0.0488691 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0486827 |
| OXR1 | oxidation resistance 1 | -0.0484449 |
| SDCBP2 | syndecan binding protein (syntenin) 2 | -0.0476907 |
| YME1L1 | YME1-like 1 ATPase | -0.0462587 |
| RPS24 | ribosomal protein S24 | -0.0461024 |
| KDM4B | lysine (K)-specific demethylase 4B | -0.0458972 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0458285 |
| WASL | Wiskott-Aldrich syndrome-like | -0.0446389 |
| PARD6B | par-6 family cell polarity regulator beta | -0.0431424 |
| PTMA | prothymosin, alpha | -0.0427862 |
| TMPRSS4 | transmembrane protease, serine 4 | -0.0425328 |
| KCNH8 | potassium channel, voltage gated eag related subfamily H, member 8 | -0.0423859 |
| FOXO1 | forkhead box O1 | -0.0422042 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0419925 |
| GLUL | glutamate-ammonia ligase | -0.0419674 |
| RPL34 | ribosomal protein L34 | -0.0401306 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0399801 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0399036 |
| IRF6 | interferon regulatory factor 6 | -0.039815 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0395748 |
| ERBB3 | erb-b2 receptor tyrosine kinase 3 | -0.0395381 |
| CATSPERB | catsper channel auxiliary subunit beta | -0.0394175 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0390303 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0387411 |
| MYO6 | myosin VI | -0.0385352 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | -0.0384094 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0379927 |
| RBM47 | RNA binding motif protein 47 | -0.0377126 |
| KDM7A | lysine (K)-specific demethylase 7A | -0.0376015 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0372887 |
| EGFR | epidermal growth factor receptor | -0.0367905 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.0367407 |
| S100A9 | S100 calcium binding protein A9 | -0.036686 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0364059 |
| ABHD17C | abhydrolase domain containing 17C | -0.0361404 |
| PPP2R2C | protein phosphatase 2, regulatory subunit B, gamma | -0.0359036 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0354151 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0353465 |
| STEAP4 | STEAP family member 4 | -0.0350588 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | -0.0346804 |
| ZNF217 | zinc finger protein 217 | -0.034505 |
| RPL26 | ribosomal protein L26 | -0.0343419 |
| TJP2 | tight junction protein 2 | -0.0342996 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0340583 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0340076 |
| STAT6 | signal transducer and activator of transcription 6, interleukin-4 induced | -0.0339942 |
| GPC6 | glypican 6 | -0.0335066 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0332903 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0329494 |
| FMNL2 | formin-like 2 | -0.0328579 |
| AFDN | afadin, adherens junction formation factor | -0.0327663 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0325153 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | -0.0322904 |
| KLF3 | Kruppel-like factor 3 (basic) | -0.0320147 |
| MEF2A | myocyte enhancer factor 2A | -0.0319999 |
| OXSR1 | oxidative stress responsive 1 | -0.0318262 |
| NUMB | numb homolog (Drosophila) | -0.0317532 |
| ACTG1 | actin gamma 1 | -0.0316146 |
| KLC1 | kinesin light chain 1 | -0.0316109 |
| ZFAND6 | zinc finger, AN1-type domain 6 | -0.0315955 |
