| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | 18β-Glycyrrhetinic acid perturbation in NCI-H2347 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the 18β-Glycyrrhetinic acid_NCI-H2347 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.122775 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.105836 |
| POTEF | POTE ankyrin domain family, member F | 0.0978375 |
| SOX4 | SRY (sex determining region Y)-box 4 | 0.0865054 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0820834 |
| LDHA | lactate dehydrogenase A | 0.0690349 |
| CSTB | cystatin B (stefin B) | 0.0643665 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0586469 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0547141 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0545443 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0543323 |
| TMEM165 | transmembrane protein 165 | 0.0529446 |
| TXNIP | thioredoxin interacting protein | 0.0521497 |
| TMF1 | TATA element modulatory factor 1 | 0.0498491 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0466128 |
| ARRDC3 | arrestin domain containing 3 | 0.0452353 |
| FTL | ferritin, light polypeptide | 0.0440791 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0428228 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0419316 |
| LMO7 | LIM domain 7 | 0.0414993 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0410021 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0408457 |
| IFITM1 | interferon induced transmembrane protein 1 | 0.0396136 |
| EFNA5 | ephrin-A5 | 0.0366941 |
| MYO6 | myosin VI | 0.0353422 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0334958 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0326726 |
| TPI1 | triosephosphate isomerase 1 | 0.0318544 |
| RPL12 | ribosomal protein L12 | 0.0312591 |
| TMSB4X | thymosin beta 4, X-linked | 0.0305085 |
| IFITM3 | interferon induced transmembrane protein 3 | 0.0303902 |
| RPS12 | ribosomal protein S12 | 0.0297323 |
| ARL6IP5 | ADP-ribosylation factor-like 6 interacting protein 5 | 0.0293133 |
| HLA-A | major histocompatibility complex, class I, A | 0.0289632 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | 0.028404 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.028042 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0277821 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0274837 |
| COPA | coatomer protein complex, subunit alpha | 0.0273504 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.026718 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 | 0.0265741 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0264479 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0264216 |
| DUSP6 | dual specificity phosphatase 6 | 0.0258167 |
| SERINC1 | serine incorporator 1 | 0.0257548 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0257258 |
| MSN | moesin | 0.0255902 |
| KDELR1 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 | 0.0254187 |
| RAP2B | RAP2B, member of RAS oncogene family | 0.0252607 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0252284 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0248358 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0247508 |
| MDK | midkine (neurite growth-promoting factor 2) | 0.0243402 |
| TMSB10 | thymosin beta 10 | 0.0243138 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0235272 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.0230773 |
| C15ORF48 | chromosome 15 open reading frame 48 | 0.0230468 |
| ADM | adrenomedullin | 0.0229605 |
| ENO1 | enolase 1, (alpha) | 0.0228613 |
| BLZF1 | basic leucine zipper nuclear factor 1 | 0.0227511 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0227 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0225681 |
| VEGFA | vascular endothelial growth factor A | 0.0225338 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.02243 |
| CDCP1 | CUB domain containing protein 1 | 0.022029 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0216994 |
| PGK1 | phosphoglycerate kinase 1 | 0.0213739 |
| RPS3 | ribosomal protein S3 | 0.0211492 |
| CD2AP | CD2-associated protein | 0.021035 |
| LAMB3 | laminin, beta 3 | 0.0209388 |
| LY6E | lymphocyte antigen 6 complex, locus E | 0.02089 |
| CLIP4 | CAP-GLY domain containing linker protein family, member 4 | 0.0208054 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0204587 |
| NCOA2 | nuclear receptor coactivator 2 | 0.0196388 |
| ESRP1 | epithelial splicing regulatory protein 1 | 0.0193234 |
| RPL18 | ribosomal protein L18 | 0.0193234 |
| CLDN12 | claudin 12 | 0.0192817 |
| NDRG1 | N-myc downstream regulated 1 | 0.0192326 |
| CTSS | cathepsin S | 0.01904 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | 0.0189657 |
| CBX3 | chromobox homolog 3 | 0.018923 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0187891 |
| TUBB4B | tubulin, beta 4B class IVb | 0.0184034 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0184001 |
| WFDC2 | WAP four-disulfide core domain 2 | 0.018177 |
| MXD1 | MAX dimerization protein 1 | 0.0179283 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.0177996 |
| NOTCH2 | notch 2 | 0.0177056 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0177021 |
| CLDN4 | claudin 4 | 0.0171663 |
| GNB2 | guanine nucleotide binding protein (G protein), beta polypeptide 2 | 0.0170676 |
| IRF7 | interferon regulatory factor 7 | 0.0169413 |
| SREK1IP1 | SREK1-interacting protein 1 | 0.0168519 |
| MCTP2 | multiple C2 domains, transmembrane 2 | 0.0167988 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0166181 |
| FAM3C | family with sequence similarity 3, member C | 0.0165113 |
| TES | testin LIM domain protein | 0.016492 |
| CIB1 | calcium and integrin binding 1 (calmyrin) | 0.0164556 |
| NR2F2 | nuclear receptor subfamily 2, group F, member 2 | 0.0164172 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.0162838 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.316574 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.284969 |
| PTMA | prothymosin, alpha | -0.155828 |
| FN1 | fibronectin 1 | -0.151439 |
| RPL35A | ribosomal protein L35a | -0.115195 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.10971 |
| RPLP1 | ribosomal protein, large, P1 | -0.106322 |
| ACTG1 | actin gamma 1 | -0.105662 |
| RPS23 | ribosomal protein S23 | -0.0782714 |
| CANX | calnexin | -0.0743892 |
| RPS29 | ribosomal protein S29 | -0.0712662 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0695735 |
| RPS6 | ribosomal protein S6 | -0.0680137 |
| RPL8 | ribosomal protein L8 | -0.0632049 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0621083 |
| UPP1 | uridine phosphorylase 1 | -0.0616567 |
| S100A10 | S100 calcium binding protein A10 | -0.0606962 |
| AHNAK | AHNAK nucleoprotein | -0.0604336 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0594814 |
| RPL34 | ribosomal protein L34 | -0.055823 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0551399 |
| RPS8 | ribosomal protein S8 | -0.0544819 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0540162 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0536604 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0528513 |
| G0S2 | G0/G1 switch 2 | -0.0518332 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0516088 |
| NAV2 | neuron navigator 2 | -0.0486582 |
| RPS13 | ribosomal protein S13 | -0.0479943 |
| DEK | DEK proto-oncogene | -0.0478643 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0476157 |
| RPLP2 | ribosomal protein, large, P2 | -0.047114 |
| RAB7A | RAB7A, member RAS oncogene family | -0.043143 |
| RPL28 | ribosomal protein L28 | -0.0424914 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0413931 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0404451 |
| PLEC | plectin | -0.0404373 |
| RPS10 | ribosomal protein S10 | -0.0402614 |
| ANXA2 | annexin A2 | -0.039969 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.039586 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0391894 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0379153 |
| PKM | pyruvate kinase, muscle | -0.0373332 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0371789 |
| EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) | -0.0364868 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0358201 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0356304 |
| SQSTM1 | sequestosome 1 | -0.0352531 |
| PTK2 | protein tyrosine kinase 2 | -0.0351418 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0351302 |
| MAP4 | microtubule-associated protein 4 | -0.0349309 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.034798 |
| RPL5 | ribosomal protein L5 | -0.0346848 |
| VIM | vimentin | -0.0342963 |
| INTS6 | integrator complex subunit 6 | -0.0341943 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0330261 |
| USP53 | ubiquitin specific peptidase 53 | -0.0329755 |
| KRT7 | keratin 7, type II | -0.0325021 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0323722 |
| RPS11 | ribosomal protein S11 | -0.0322309 |
| VCL | vinculin | -0.0321646 |
| PALLD | palladin, cytoskeletal associated protein | -0.0313637 |
| RPS20 | ribosomal protein S20 | -0.0310757 |
| RHEB | Ras homolog enriched in brain | -0.0305621 |
| GNAS | GNAS complex locus | -0.0303502 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0301923 |
| MCL1 | myeloid cell leukemia 1 | -0.0301642 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0301311 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.0300047 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0298856 |
| FHIT | fragile histidine triad | -0.0298191 |
| TRAF3 | TNF receptor-associated factor 3 | -0.0296657 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0295184 |
| DSPP | dentin sialophosphoprotein | -0.0287502 |
| SPAG9 | sperm associated antigen 9 | -0.0287255 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.028556 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0282454 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0282412 |
| PPP1R13B | protein phosphatase 1, regulatory subunit 13B | -0.0280692 |
| APP | amyloid beta (A4) precursor protein | -0.0279907 |
| GOLGA4 | golgin A4 | -0.0279041 |
| LDHB | lactate dehydrogenase B | -0.0277408 |
| RYBP | RING1 and YY1 binding protein | -0.0277319 |
| KIAA1217 | KIAA1217 | -0.0276726 |
| RPL38 | ribosomal protein L38 | -0.0275002 |
| RPS27A | ribosomal protein S27a | -0.0271178 |
| WNK1 | WNK lysine deficient protein kinase 1 | -0.0271066 |
| TBCA | tubulin folding cofactor A | -0.0270004 |
| HMGB1 | high mobility group box 1 | -0.0267718 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0267596 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0266719 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0266625 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | -0.0266174 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0264857 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0264316 |
| SEPTIN11 | septin 11 | -0.0261703 |
| ASPH | aspartate beta-hydroxylase | -0.026156 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0259457 |
| SERINC5 | serine incorporator 5 | -0.025671 |
| DST | dystonin | -0.0256217 |
