| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | 18β-Glycyrrhetinic acid perturbation in PANC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the 18β-Glycyrrhetinic acid_PANC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.206577 |
| MT2A | metallothionein 2A | 0.161641 |
| RPS3 | ribosomal protein S3 | 0.107242 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.106921 |
| RPS12 | ribosomal protein S12 | 0.104142 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0944382 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0906989 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0868565 |
| RPL23 | ribosomal protein L23 | 0.0853634 |
| RPL12 | ribosomal protein L12 | 0.0791357 |
| SFTPA2 | surfactant protein A2 | 0.0780134 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0705453 |
| B2M | beta-2-microglobulin | 0.0666445 |
| RPL37A | ribosomal protein L37a | 0.0613741 |
| RPLP1 | ribosomal protein, large, P1 | 0.0601737 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0594842 |
| RPLP0 | ribosomal protein, large, P0 | 0.0563835 |
| PCBP2 | poly(rC) binding protein 2 | 0.0555565 |
| RPS17 | ribosomal protein S17 | 0.0540404 |
| YBX1 | Y box binding protein 1 | 0.0525215 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0511325 |
| RPS19 | ribosomal protein S19 | 0.0507442 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0501106 |
| ZFP36 | ZFP36 ring finger protein | 0.0494972 |
| RPL11 | ribosomal protein L11 | 0.0473972 |
| RACK1 | receptor for activated C kinase 1 | 0.0467079 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0454436 |
| RPL36 | ribosomal protein L36 | 0.0446693 |
| KLF6 | Kruppel-like factor 6 | 0.0435207 |
| RPS6 | ribosomal protein S6 | 0.0427108 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0422549 |
| ENO1 | enolase 1, (alpha) | 0.0417815 |
| RPLP2 | ribosomal protein, large, P2 | 0.0411353 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0409607 |
| SAMD4B | sterile alpha motif domain containing 4B | 0.040184 |
| TXNRD1 | thioredoxin reductase 1 | 0.0398092 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0396333 |
| MATR3 | matrin 3 | 0.0392973 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0382706 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0379426 |
| CENPF | centromere protein F, 350/400kDa | 0.0367772 |
| ASPH | aspartate beta-hydroxylase | 0.0365661 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0364512 |
| SERINC1 | serine incorporator 1 | 0.0363181 |
| MFGE8 | milk fat globule-EGF factor 8 protein | 0.0360754 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | 0.0358188 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0355218 |
| RPL7 | ribosomal protein L7 | 0.0351539 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0340162 |
| RPL26 | ribosomal protein L26 | 0.033214 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.032804 |
| ARRDC3 | arrestin domain containing 3 | 0.0326637 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0323186 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0321354 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0316013 |
| RPS4X | ribosomal protein S4, X-linked | 0.0314132 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.0311352 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0310142 |
| EIF5B | eukaryotic translation initiation factor 5B | 0.0304249 |
| RPL37 | ribosomal protein L37 | 0.0303752 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0303484 |
| IPO7 | importin 7 | 0.0296836 |
| SMAD3 | SMAD family member 3 | 0.0296598 |
| RPS27 | ribosomal protein S27 | 0.0295465 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0292262 |
| VEGFA | vascular endothelial growth factor A | 0.0289481 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | 0.0287469 |
| RPS2 | ribosomal protein S2 | 0.0281097 |
| RPL18 | ribosomal protein L18 | 0.0279391 |
| IFITM3 | interferon induced transmembrane protein 3 | 0.0272369 |
| HLA-A | major histocompatibility complex, class I, A | 0.0272079 |
| FTL | ferritin, light polypeptide | 0.0271591 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0271189 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.027091 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0270909 |
| RPL30 | ribosomal protein L30 | 0.0270304 |
| RPL9 | ribosomal protein L9 | 0.0268079 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0264545 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0264195 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | 0.0260025 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0259572 |
| ZNF146 | zinc finger protein 146 | 0.0258965 |
| RPS14 | ribosomal protein S14 | 0.0257382 |
| ZNF292 | zinc finger protein 292 | 0.0256001 |
| SSB | Sjogren syndrome antigen B (autoantigen La) | 0.0255485 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0253985 |
| LDHA | lactate dehydrogenase A | 0.025362 |
| CBX3 | chromobox homolog 3 | 0.0250271 |
| SLK | STE20-like kinase | 0.0248447 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | 0.0245649 |
| SLC25A3 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 | 0.0244862 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.0244635 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0244214 |
| RPL21 | ribosomal protein L21 | 0.0244188 |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) | 0.0243149 |
| RPL31 | ribosomal protein L31 | 0.0241979 |
| AFDN | afadin, adherens junction formation factor | 0.0241681 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | 0.0241224 |
| FOSL1 | FOS-like antigen 1 | 0.0241095 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0239275 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.196238 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.196167 |
| VIM | vimentin | -0.180816 |
| AHNAK | AHNAK nucleoprotein | -0.16323 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.12923 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.103648 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0991001 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0877913 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0819757 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0783248 |
| ACTG1 | actin gamma 1 | -0.0738193 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.070233 |
| TMEM123 | transmembrane protein 123 | -0.0700205 |
| CTSD | cathepsin D | -0.063671 |
| FBL | fibrillarin | -0.0577804 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0544385 |
| DST | dystonin | -0.0533082 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.0520209 |
| ATG7 | autophagy related 7 | -0.0516341 |
| CD44 | CD44 molecule (Indian blood group) | -0.0515746 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0505577 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0482648 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0474073 |
| HMGA2 | high mobility group AT-hook 2 | -0.0457699 |
| AFAP1 | actin filament associated protein 1 | -0.045284 |
| FMNL2 | formin-like 2 | -0.0422265 |
| UBC | ubiquitin C | -0.0417689 |
| MYO10 | myosin X | -0.0407962 |
| SPAG9 | sperm associated antigen 9 | -0.0395906 |
| NAV2 | neuron navigator 2 | -0.0388967 |
| ACTN4 | actinin, alpha 4 | -0.0385748 |
| H1-0 | H1.0 linker histone | -0.0375719 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0372738 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | -0.0364528 |
| CCND1 | cyclin D1 | -0.035186 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0348232 |
| PTK2 | protein tyrosine kinase 2 | -0.0346982 |
| MAP4 | microtubule-associated protein 4 | -0.0343963 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.0328936 |
| KRT8 | keratin 8, type II | -0.0327698 |
| RNF220 | ring finger protein 220 | -0.031603 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0315825 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0308637 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0306209 |
| WASF2 | WAS protein family, member 2 | -0.0300452 |
| CANX | calnexin | -0.0298014 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0294688 |
| TPM1 | tropomyosin 1 (alpha) | -0.0291451 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0278617 |
| CD109 | CD109 molecule | -0.0277582 |
| JPT2 | Jupiter microtubule associated homolog 2 | -0.0275839 |
| NF1 | neurofibromin 1 | -0.0275235 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0273986 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0273337 |
| RIGI | RNA sensor RIG-I | -0.02729 |
| WDR45B | WD repeat domain 45B | -0.0272567 |
| SBF2 | SET binding factor 2 | -0.0272432 |
| S100A6 | S100 calcium binding protein A6 | -0.0267826 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0264662 |
| FUS | FUS RNA binding protein | -0.0259865 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0259419 |
| EHBP1 | EH domain binding protein 1 | -0.0258792 |
| FBXO17 | F-box protein 17 | -0.0255493 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0253275 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.0252542 |
| TNS3 | tensin 3 | -0.024864 |
| UPP1 | uridine phosphorylase 1 | -0.0245315 |
| NHSL1 | NHS-like 1 | -0.0240964 |
| PRSS23 | protease, serine, 23 | -0.0239373 |
| VDAC1 | voltage-dependent anion channel 1 | -0.023789 |
| FBXO27 | F-box protein 27 | -0.023752 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0233614 |
| TCF12 | transcription factor 12 | -0.0226437 |
| TAOK1 | TAO kinase 1 | -0.0225595 |
| KRT18 | keratin 18, type I | -0.022507 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | -0.0223878 |
| SEPTIN9 | septin 9 | -0.0223723 |
| COL18A1 | collagen, type XVIII, alpha 1 | -0.0221653 |
| FRMD5 | FERM domain containing 5 | -0.0218871 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0217325 |
| TPM2 | tropomyosin 2 (beta) | -0.021693 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0213154 |
| FNIP1 | folliculin interacting protein 1 | -0.0212593 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0212132 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0211498 |
| LRCH3 | leucine-rich repeats and calponin homology (CH) domain containing 3 | -0.0209052 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0207551 |
| MYOF | myoferlin | -0.02074 |
| PFN1 | profilin 1 | -0.0206422 |
| RBM3 | RNA binding motif (RNP1, RRM) protein 3 | -0.0205524 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.020396 |
| TRMT112 | tRNA methyltransferase 11-2 homolog (S. cerevisiae) | -0.0201524 |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase | -0.0200553 |
| UBAP2 | ubiquitin associated protein 2 | -0.019951 |
| LMNA | lamin A/C | -0.0197894 |
| CALR | calreticulin | -0.0197688 |
| ANXA2 | annexin A2 | -0.0196823 |
| NSD2 | nuclear receptor binding SET domain protein 2 | -0.0191292 |
| RTN4 | reticulon 4 | -0.0189525 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | -0.0189173 |
