| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | 18β-Glycyrrhetinic acid perturbation in Panc 03.27 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the 18β-Glycyrrhetinic acid_Panc 03.27 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.117392 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.113318 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0974838 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0947099 |
| POTEF | POTE ankyrin domain family, member F | 0.0876986 |
| B2M | beta-2-microglobulin | 0.0787071 |
| PCBP2 | poly(rC) binding protein 2 | 0.0764888 |
| TJP1 | tight junction protein 1 | 0.0756757 |
| RPL23 | ribosomal protein L23 | 0.0748118 |
| HMGA1 | high mobility group AT-hook 1 | 0.0747829 |
| CCNL1 | cyclin L1 | 0.0687472 |
| RPS3 | ribosomal protein S3 | 0.0637586 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0619152 |
| INTS6 | integrator complex subunit 6 | 0.0573165 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0570434 |
| RIMKLB | ribosomal modification protein rimK-like family member B | 0.0567361 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0557061 |
| NDRG1 | N-myc downstream regulated 1 | 0.0550343 |
| RPL37A | ribosomal protein L37a | 0.054594 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0531615 |
| RPS12 | ribosomal protein S12 | 0.0521865 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0487808 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.048511 |
| RPS19 | ribosomal protein S19 | 0.0470352 |
| HLA-A | major histocompatibility complex, class I, A | 0.0468285 |
| AREG | amphiregulin | 0.0463431 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0454632 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0453738 |
| VEGFA | vascular endothelial growth factor A | 0.044962 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.04478 |
| RPL21 | ribosomal protein L21 | 0.0445053 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | 0.0444293 |
| CLDN4 | claudin 4 | 0.044405 |
| RPS17 | ribosomal protein S17 | 0.0440882 |
| MT2A | metallothionein 2A | 0.0437007 |
| FOSL1 | FOS-like antigen 1 | 0.0433864 |
| TPI1 | triosephosphate isomerase 1 | 0.0430961 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0420604 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0416362 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.041597 |
| MYO1E | myosin IE | 0.0407707 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0393014 |
| PLPP6 | phospholipid phosphatase 6 | 0.0385303 |
| DUSP5 | dual specificity phosphatase 5 | 0.0382291 |
| OXSR1 | oxidative stress responsive 1 | 0.0379759 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0378594 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0370289 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0368793 |
| RPL9 | ribosomal protein L9 | 0.0367899 |
| C3 | complement component 3 | 0.0360357 |
| MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | 0.0358349 |
| RASAL2 | RAS protein activator like 2 | 0.0357435 |
| IRS2 | insulin receptor substrate 2 | 0.0353009 |
| RPL31 | ribosomal protein L31 | 0.0351778 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0343356 |
| RPL12 | ribosomal protein L12 | 0.0339843 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0333303 |
| SGMS2 | sphingomyelin synthase 2 | 0.0332209 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | 0.0331838 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0328484 |
| TXNIP | thioredoxin interacting protein | 0.0327015 |
| ATF3 | activating transcription factor 3 | 0.0324785 |
| BRD2 | bromodomain containing 2 | 0.0324162 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0323028 |
| FTL | ferritin, light polypeptide | 0.0322329 |
| RPL18 | ribosomal protein L18 | 0.0320139 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0319543 |
| HBEGF | heparin-binding EGF-like growth factor | 0.0317623 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0314885 |
| RPS14 | ribosomal protein S14 | 0.0308937 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0308205 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0303396 |
| PLAU | plasminogen activator, urokinase | 0.0301584 |
| NAV2 | neuron navigator 2 | 0.030088 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | 0.0300622 |
| SRSF3 | serine/arginine-rich splicing factor 3 | 0.0300594 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0299183 |
| MED13 | mediator complex subunit 13 | 0.0297902 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0291783 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0290869 |
| IFITM1 | interferon induced transmembrane protein 1 | 0.0289451 |
| ADAMTS9 | ADAM metallopeptidase with thrombospondin type 1 motif, 9 | 0.0285787 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0285704 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0281229 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0281191 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0279576 |
| JUP | junction plakoglobin | 0.0279018 |
| SQSTM1 | sequestosome 1 | 0.0276214 |
| RPS13 | ribosomal protein S13 | 0.0270276 |
| RPL36 | ribosomal protein L36 | 0.0267139 |
| RPL19 | ribosomal protein L19 | 0.0266543 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0265368 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0265309 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0262689 |
| WWC1 | WW and C2 domain containing 1 | 0.0261575 |
| RPL37 | ribosomal protein L37 | 0.0261034 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0259839 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 0.0258125 |
| TES | testin LIM domain protein | 0.0258026 |
| PCDH1 | protocadherin 1 | 0.0256709 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB4X | thymosin beta 4, X-linked | -0.185443 |
| AHNAK | AHNAK nucleoprotein | -0.127592 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.114511 |
| TPM4 | tropomyosin 4 | -0.0939548 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.091745 |
| DSG2 | desmoglein 2 | -0.0874968 |
| PTMA | prothymosin, alpha | -0.0870357 |
| ANXA2 | annexin A2 | -0.0862213 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0818105 |
| ACTG1 | actin gamma 1 | -0.0803216 |
| CANX | calnexin | -0.0798663 |
| HLA-E | major histocompatibility complex, class I, E | -0.0767355 |
| EMP1 | epithelial membrane protein 1 | -0.0749959 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0721412 |
| CD2AP | CD2-associated protein | -0.0716543 |
| VCL | vinculin | -0.0709707 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0672103 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0646142 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0626578 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0586675 |
| KRT7 | keratin 7, type II | -0.0585534 |
| KRT19 | keratin 19, type I | -0.0564272 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0554972 |
| TMEM123 | transmembrane protein 123 | -0.0530583 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0516797 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0514601 |
| MUC4 | mucin 4, cell surface associated | -0.0504596 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0502936 |
| LAMC2 | laminin, gamma 2 | -0.0490561 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0484315 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0483211 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.047684 |
| RIGI | RNA sensor RIG-I | -0.0439151 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | -0.0426249 |
| ACTN4 | actinin, alpha 4 | -0.0421944 |
| ANLN | anillin, actin binding protein | -0.0419837 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0409639 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0406652 |
| H1-0 | H1.0 linker histone | -0.0404701 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0392924 |
| HLA-B | major histocompatibility complex, class I, B | -0.0391414 |
| MUC20 | mucin 20, cell surface associated | -0.0385986 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0384357 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0381548 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0380404 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0379635 |
| PLSCR1 | phospholipid scramblase 1 | -0.0378172 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0375404 |
| HLA-C | major histocompatibility complex, class I, C | -0.0373067 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0370227 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0363452 |
| SYNGAP1 | synaptic Ras GTPase activating protein 1 | -0.0362436 |
| RPL34 | ribosomal protein L34 | -0.0359695 |
| RRBP1 | ribosome binding protein 1 | -0.0353674 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0353341 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0353228 |
| SYT14 | synaptotagmin XIV | -0.0350922 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0350021 |
| SP100 | SP100 nuclear antigen | -0.0343669 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.033991 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0337031 |
| JAK1 | Janus kinase 1 | -0.0332296 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0332174 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0331109 |
| KRT17 | keratin 17, type I | -0.0328441 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0325405 |
| GNAS | GNAS complex locus | -0.0324703 |
| RIOK3 | RIO kinase 3 | -0.0324188 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0323954 |
| KRT18 | keratin 18, type I | -0.032338 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0321263 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.0320804 |
| PHF3 | PHD finger protein 3 | -0.0319476 |
| NSD3 | nuclear receptor binding SET domain protein 3 | -0.031875 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.031764 |
| ETV6 | ets variant 6 | -0.0314665 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0314073 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0311939 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0310408 |
| OGA | O-GlcNAcase | -0.030989 |
| RNF213 | ring finger protein 213 | -0.030596 |
| EFNA5 | ephrin-A5 | -0.0304102 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0302449 |
| RUNX1 | runt-related transcription factor 1 | -0.0300626 |
| SULF2 | sulfatase 2 | -0.0298285 |
| ARF1 | ADP-ribosylation factor 1 | -0.0294479 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0294441 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0294183 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0293242 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.028714 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | -0.0285629 |
| KRT8 | keratin 8, type II | -0.0285525 |
| APP | amyloid beta (A4) precursor protein | -0.0283206 |
| LAMA4 | laminin, alpha 4 | -0.0282905 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.028218 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0277377 |
| SERPINB6 | serpin peptidase inhibitor, clade B (ovalbumin), member 6 | -0.027556 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | -0.0271065 |
| LASP1 | LIM and SH3 protein 1 | -0.0268956 |
| PARD3 | par-3 family cell polarity regulator | -0.0265472 |
