| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | 18β-Glycyrrhetinic acid perturbation in RKO cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the 18β-Glycyrrhetinic acid_RKO drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FTL | ferritin, light polypeptide | 0.0899452 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0681149 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0673 |
| FLNB | filamin B, beta | 0.0665974 |
| HMGA1 | high mobility group AT-hook 1 | 0.0651322 |
| TMSB10 | thymosin beta 10 | 0.0617063 |
| RPS12 | ribosomal protein S12 | 0.0599442 |
| RPS17 | ribosomal protein S17 | 0.0550604 |
| RACK1 | receptor for activated C kinase 1 | 0.0529902 |
| FOSL1 | FOS-like antigen 1 | 0.0475763 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0459401 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0448852 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0435408 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0434327 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0421982 |
| SHANK1 | SH3 and multiple ankyrin repeat domains 1 | 0.0411259 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.0410385 |
| LDHA | lactate dehydrogenase A | 0.0402097 |
| RPL12 | ribosomal protein L12 | 0.040143 |
| MCL1 | myeloid cell leukemia 1 | 0.0390637 |
| RPL23 | ribosomal protein L23 | 0.0384585 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0381786 |
| RPS4X | ribosomal protein S4, X-linked | 0.0380777 |
| SGMS2 | sphingomyelin synthase 2 | 0.0366126 |
| RPS3 | ribosomal protein S3 | 0.0362385 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0361074 |
| CD68 | CD68 molecule | 0.0352979 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | 0.0349462 |
| HLA-A | major histocompatibility complex, class I, A | 0.034879 |
| RPL36 | ribosomal protein L36 | 0.034693 |
| UBXN4 | UBX domain protein 4 | 0.0342405 |
| RPL37 | ribosomal protein L37 | 0.0336292 |
| RPL7 | ribosomal protein L7 | 0.0335669 |
| PSMD2 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 | 0.0332841 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0326757 |
| STC1 | stanniocalcin 1 | 0.0325361 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | 0.0317538 |
| CREB5 | cAMP responsive element binding protein 5 | 0.030696 |
| JMJD1C | jumonji domain containing 1C | 0.0304751 |
| B2M | beta-2-microglobulin | 0.0299387 |
| MAPK8 | mitogen-activated protein kinase 8 | 0.0299076 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0295596 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.0295596 |
| TOR1AIP2 | torsin A interacting protein 2 | 0.0291696 |
| RPL18 | ribosomal protein L18 | 0.0291085 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0290744 |
| S100A11 | S100 calcium binding protein A11 | 0.0289488 |
| CDK17 | cyclin-dependent kinase 17 | 0.028785 |
| GLRX | glutaredoxin (thioltransferase) | 0.0286033 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0284203 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0277163 |
| YBX3 | Y box binding protein 3 | 0.0273239 |
| RPL37A | ribosomal protein L37a | 0.0270683 |
| CAPRIN2 | caprin family member 2 | 0.0269938 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0268982 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.0267998 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0264053 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0261955 |
| CYP51A1 | cytochrome P450, family 51, subfamily A, polypeptide 1 | 0.026169 |
| LIMA1 | LIM domain and actin binding 1 | 0.0261438 |
| KLF6 | Kruppel-like factor 6 | 0.0257029 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0256057 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.025602 |
| CD44 | CD44 molecule (Indian blood group) | 0.0255816 |
| RPS2 | ribosomal protein S2 | 0.0255707 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0252166 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0250079 |
| RO60 | Ro60, Y RNA binding protein | 0.0248808 |
| EFL1 | elongation factor like GTPase 1 | 0.0247629 |
| FAM13A | family with sequence similarity 13, member A | 0.0246738 |
| RPL11 | ribosomal protein L11 | 0.0242077 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0239397 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0238954 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0232249 |
| PAICS | phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase | 0.0231903 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0231392 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0230772 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0222643 |
| RPL32 | ribosomal protein L32 | 0.0221049 |
| DUSP6 | dual specificity phosphatase 6 | 0.0220627 |
| TUT7 | terminal uridylyl transferase 7 | 0.0219478 |
| JUN | jun proto-oncogene | 0.021812 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0218028 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0217564 |
| IER2 | immediate early response 2 | 0.0217478 |
| CCDC88A | coiled-coil domain containing 88A | 0.021732 |
| GPHN | gephyrin | 0.0216479 |
| C6ORF62 | chromosome 6 open reading frame 62 | 0.0216305 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0215781 |
| CBX3 | chromobox homolog 3 | 0.0215083 |
| PFN1 | profilin 1 | 0.0213909 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0212266 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0211069 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0207412 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0206067 |
| EML4 | echinoderm microtubule associated protein like 4 | 0.0204973 |
| ANXA5 | annexin A5 | 0.0202441 |
| RPS14 | ribosomal protein S14 | 0.0202225 |
| EGR1 | early growth response 1 | 0.0201846 |
| ANGPTL4 | angiopoietin-like 4 | 0.0199047 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DLC1 | DLC1 Rho GTPase activating protein | -0.178568 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.166951 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.127108 |
| RPL35A | ribosomal protein L35a | -0.124475 |
| PTMA | prothymosin, alpha | -0.10704 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0904291 |
| RPLP1 | ribosomal protein, large, P1 | -0.0742734 |
| RPS8 | ribosomal protein S8 | -0.0647172 |
| TTR | transthyretin | -0.0625928 |
| CANX | calnexin | -0.0569884 |
| RPL7A | ribosomal protein L7a | -0.0558793 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0536528 |
| PTK2 | protein tyrosine kinase 2 | -0.0517385 |
| RPS20 | ribosomal protein S20 | -0.0497516 |
| RPLP2 | ribosomal protein, large, P2 | -0.0474141 |
| RPL34 | ribosomal protein L34 | -0.0444163 |
| ACTG1 | actin gamma 1 | -0.0443313 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.044088 |
| RAB3IP | RAB3A interacting protein | -0.0439717 |
| RRBP1 | ribosome binding protein 1 | -0.042956 |
| RPS24 | ribosomal protein S24 | -0.0423915 |
| PCNX4 | pecanex 4 | -0.0422182 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0420854 |
| NABP1 | nucleic acid binding protein 1 | -0.0414289 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0407562 |
| NAV3 | neuron navigator 3 | -0.0399863 |
| RPS29 | ribosomal protein S29 | -0.0398075 |
| RPS21 | ribosomal protein S21 | -0.0392758 |
| RPL38 | ribosomal protein L38 | -0.0386948 |
| NUDCD1 | NudC domain containing 1 | -0.038216 |
| APP | amyloid beta (A4) precursor protein | -0.037679 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0367031 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | -0.0360464 |
| RPS25 | ribosomal protein S25 | -0.0359109 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0356381 |
| RPL39 | ribosomal protein L39 | -0.0349944 |
| RPL8 | ribosomal protein L8 | -0.0346971 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0341948 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0339697 |
| CSTF3 | cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa | -0.0336629 |
| MKI67 | marker of proliferation Ki-67 | -0.0336297 |
| PARD3 | par-3 family cell polarity regulator | -0.0329841 |
| RPL14 | ribosomal protein L14 | -0.0326401 |
| MTAP | methylthioadenosine phosphorylase | -0.0326213 |
| SNX14 | sorting nexin 14 | -0.0313817 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0313077 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0312808 |
| NAV2 | neuron navigator 2 | -0.0311226 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 | -0.0307127 |
| GNAS | GNAS complex locus | -0.0305552 |
| RIGI | RNA sensor RIG-I | -0.030385 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0301169 |
| KIF5B | kinesin family member 5B | -0.0300136 |
| NSD3 | nuclear receptor binding SET domain protein 3 | -0.0299981 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0297469 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0296637 |
| LAMB3 | laminin, beta 3 | -0.0288424 |
| TBC1D22A | TBC1 domain family, member 22A | -0.028349 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0278616 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.027756 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | -0.0276476 |
| RPL13A | ribosomal protein L13a | -0.027364 |
| DEK | DEK proto-oncogene | -0.0272441 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0270996 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0270614 |
| AHNAK | AHNAK nucleoprotein | -0.0268401 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.0266294 |
| VCL | vinculin | -0.0266177 |
| CALU | calumenin | -0.026578 |
| FRMD6 | FERM domain containing 6 | -0.0263825 |
| RPS16 | ribosomal protein S16 | -0.0263439 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0262056 |
| CALD1 | caldesmon 1 | -0.0261493 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0261022 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0257934 |
| TPM4 | tropomyosin 4 | -0.0254075 |
| BNC2 | basonuclin 2 | -0.0251103 |
| SP100 | SP100 nuclear antigen | -0.0250887 |
| PSMB7 | proteasome (prosome, macropain) subunit, beta type, 7 | -0.0248191 |
| RAN | RAN, member RAS oncogene family | -0.0247823 |
| CUX1 | cut-like homeobox 1 | -0.0245703 |
| DIAPH3 | diaphanous-related formin 3 | -0.0240906 |
| CDK12 | cyclin-dependent kinase 12 | -0.023812 |
| RPS6 | ribosomal protein S6 | -0.0237482 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0237185 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0236252 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0234611 |
| ASPH | aspartate beta-hydroxylase | -0.0234511 |
| TBCA | tubulin folding cofactor A | -0.0234504 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0232847 |
| UBE2K | ubiquitin-conjugating enzyme E2K | -0.0232237 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0230668 |
| TRMT11 | tRNA methyltransferase 11 homolog (S. cerevisiae) | -0.023063 |
| NSD2 | nuclear receptor binding SET domain protein 2 | -0.0230622 |
| NAA15 | N(alpha)-acetyltransferase 15, NatA auxiliary subunit | -0.0228157 |
| PNPT1 | polyribonucleotide nucleotidyltransferase 1 | -0.0227351 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0227326 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | -0.0226219 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0225977 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0224539 |
