| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | 18β-Glycyrrhetinic acid perturbation in RPMI-7951 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the 18β-Glycyrrhetinic acid_RPMI-7951 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | 0.172263 |
| FTL | ferritin, light polypeptide | 0.0932487 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.073643 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0690438 |
| B2M | beta-2-microglobulin | 0.0664757 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0615572 |
| IFITM3 | interferon induced transmembrane protein 3 | 0.0502341 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0491699 |
| TMSB10 | thymosin beta 10 | 0.0462607 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0449733 |
| RPS19 | ribosomal protein S19 | 0.0420497 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0420279 |
| KYNU | kynureninase | 0.0404808 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0404796 |
| FAM162A | family with sequence similarity 162, member A | 0.035166 |
| PLIN2 | perilipin 2 | 0.0342115 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0339576 |
| EGR1 | early growth response 1 | 0.033743 |
| TPI1 | triosephosphate isomerase 1 | 0.0332584 |
| RPLP1 | ribosomal protein, large, P1 | 0.0327552 |
| LDHA | lactate dehydrogenase A | 0.0324625 |
| HLA-A | major histocompatibility complex, class I, A | 0.0320713 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0316611 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0315286 |
| RPL23 | ribosomal protein L23 | 0.0306111 |
| RPL35A | ribosomal protein L35a | 0.0305026 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0304312 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0294366 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.028738 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0285732 |
| RPS8 | ribosomal protein S8 | 0.0285245 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0272529 |
| ATP5F1E | ATP synthase F1 subunit epsilon | 0.025763 |
| RPS21 | ribosomal protein S21 | 0.0256617 |
| RPS4X | ribosomal protein S4, X-linked | 0.0255746 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | 0.0250927 |
| HMGA2 | high mobility group AT-hook 2 | 0.0250268 |
| RACK1 | receptor for activated C kinase 1 | 0.0250156 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0247459 |
| NSUN6 | NOP2/Sun domain family, member 6 | 0.0246282 |
| RPL11 | ribosomal protein L11 | 0.0246258 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0244654 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0241596 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0239458 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | 0.023807 |
| UBA52 | ubiquitin A-52 residue ribosomal protein fusion product 1 | 0.022945 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0227575 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.022665 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0225979 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0225646 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | 0.0222015 |
| IFI44L | interferon-induced protein 44-like | 0.0221827 |
| SEC61G | Sec61 gamma subunit | 0.0220325 |
| NCOA7 | nuclear receptor coactivator 7 | 0.021779 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0216206 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | 0.0214996 |
| IFITM1 | interferon induced transmembrane protein 1 | 0.0214547 |
| RPLP0 | ribosomal protein, large, P0 | 0.0210999 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0209649 |
| TMEM132D | transmembrane protein 132D | 0.0208733 |
| VCL | vinculin | 0.0208345 |
| RPS24 | ribosomal protein S24 | 0.0205238 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0200257 |
| RPLP2 | ribosomal protein, large, P2 | 0.019423 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0193532 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0193296 |
| PLP2 | proteolipid protein 2 (colonic epithelium-enriched) | 0.0192314 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | 0.0192247 |
| ENO1 | enolase 1, (alpha) | 0.0188536 |
| CCT6A | chaperonin containing TCP1, subunit 6A (zeta 1) | 0.018804 |
| SHISA5 | shisa family member 5 | 0.0187969 |
| RPL37A | ribosomal protein L37a | 0.0187137 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | 0.0187114 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.018699 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0185847 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | 0.0185077 |
| RPS17 | ribosomal protein S17 | 0.0184859 |
| STAU1 | staufen double-stranded RNA binding protein 1 | 0.0184253 |
| SRP14 | signal recognition particle 14kDa (homologous Alu RNA binding protein) | 0.018124 |
| YBX1 | Y box binding protein 1 | 0.0181139 |
| BPTF | bromodomain PHD finger transcription factor | 0.0179464 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0177409 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.0177199 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0174951 |
| TES | testin LIM domain protein | 0.0173071 |
| ANXA2 | annexin A2 | 0.0171994 |
| RPL8 | ribosomal protein L8 | 0.0171481 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.017131 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | 0.0171203 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0170445 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0168677 |
| RPS14 | ribosomal protein S14 | 0.0168548 |
| EZR | ezrin | 0.0168495 |
| TLE4 | transducin-like enhancer of split 4 | 0.0167579 |
| SFTPA2 | surfactant protein A2 | 0.0167496 |
| INTS6 | integrator complex subunit 6 | 0.0167099 |
| LMO7 | LIM domain 7 | 0.0165073 |
| RPS16 | ribosomal protein S16 | 0.0164422 |
| SKAP2 | src kinase associated phosphoprotein 2 | 0.0164192 |
| PRELID2 | PRELI domain containing 2 | 0.0163269 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.328342 |
| COL1A1 | collagen, type I, alpha 1 | -0.116992 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.107136 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.101983 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0989977 |
| COL5A1 | collagen, type V, alpha 1 | -0.092788 |
| GOLGA4 | golgin A4 | -0.0901332 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0814113 |
| COL1A2 | collagen, type I, alpha 2 | -0.0743072 |
| CDH13 | cadherin 13 | -0.0716699 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0693789 |
| YEATS2 | YEATS domain containing 2 | -0.0661497 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0643586 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0621368 |
| MMP12 | matrix metallopeptidase 12 | -0.0611553 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0578645 |
| ATP13A3 | ATPase type 13A3 | -0.057098 |
| LOXL2 | lysyl oxidase-like 2 | -0.053922 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0527424 |
| FRMD4A | FERM domain containing 4A | -0.0521086 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0517699 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0494255 |
| TPM4 | tropomyosin 4 | -0.0472007 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0463901 |
| CALR | calreticulin | -0.0448687 |
| MSN | moesin | -0.0447495 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0444524 |
| NDRG1 | N-myc downstream regulated 1 | -0.0440593 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0439621 |
| NRP1 | neuropilin 1 | -0.0431673 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.043134 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0428003 |
| FMNL2 | formin-like 2 | -0.0415086 |
| ZNF292 | zinc finger protein 292 | -0.0410295 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0408606 |
| FLNB | filamin B, beta | -0.0405832 |
| GLIS3 | GLIS family zinc finger 3 | -0.0404299 |
| AFAP1 | actin filament associated protein 1 | -0.0397696 |
| DST | dystonin | -0.038912 |
| PCBP3 | poly(rC) binding protein 3 | -0.0386197 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0374441 |
| MCTP2 | multiple C2 domains, transmembrane 2 | -0.0366061 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.03658 |
| MAP4 | microtubule-associated protein 4 | -0.0359884 |
| SH3RF3 | SH3 domain containing ring finger 3 | -0.0356294 |
| CALD1 | caldesmon 1 | -0.0347526 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0345056 |
| CD109 | CD109 molecule | -0.0343307 |
| CDK19 | cyclin-dependent kinase 19 | -0.033691 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | -0.0333104 |
| RNF24 | ring finger protein 24 | -0.0332281 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.0328119 |
| NUMB | numb homolog (Drosophila) | -0.0326816 |
| SYNDIG1 | synapse differentiation inducing 1 | -0.032187 |
| ADAM12 | ADAM metallopeptidase domain 12 | -0.032177 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -0.0319086 |
| CDCP1 | CUB domain containing protein 1 | -0.0315756 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0315605 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | -0.0315117 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0309199 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.0305856 |
| USP34 | ubiquitin specific peptidase 34 | -0.0304737 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | -0.0304349 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0301518 |
| MYO1B | myosin IB | -0.0299124 |
| ARRDC3 | arrestin domain containing 3 | -0.0297151 |
| STK10 | serine/threonine kinase 10 | -0.0296507 |
| NKTR | natural killer cell triggering receptor | -0.0294638 |
| SEC24D | SEC24 family member D | -0.0294574 |
| PLEC | plectin | -0.0293526 |
| NAV1 | neuron navigator 1 | -0.0292548 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | -0.029022 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0287219 |
| HIP1 | huntingtin interacting protein 1 | -0.0286785 |
| CALU | calumenin | -0.02796 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | -0.0278243 |
| TRIM56 | tripartite motif containing 56 | -0.0277432 |
| CAPZB | capping protein (actin filament) muscle Z-line, beta | -0.027442 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0273311 |
| CTSB | cathepsin B | -0.0271965 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.02707 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0269745 |
| FAM20C | family with sequence similarity 20, member C | -0.0269004 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0268254 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0267735 |
| MTSS1 | metastasis suppressor 1 | -0.0265242 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0265018 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0263782 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0263393 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0262692 |
| AHNAK | AHNAK nucleoprotein | -0.0262264 |
| DCAF6 | DDB1 and CUL4 associated factor 6 | -0.0261113 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0260734 |
| NF1 | neurofibromin 1 | -0.026044 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0259752 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0258365 |
| SBF2 | SET binding factor 2 | -0.0257644 |
| FBN1 | fibrillin 1 | -0.0257337 |
| XPO1 | exportin 1 | -0.0256404 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0254535 |
