| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | 18β-Glycyrrhetinic acid perturbation in SHP-77 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the 18β-Glycyrrhetinic acid_SHP-77 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NALF1 | NALCN channel auxiliary factor 1 | 0.147301 |
| MT2A | metallothionein 2A | 0.115503 |
| STC1 | stanniocalcin 1 | 0.111566 |
| GPC6 | glypican 6 | 0.107018 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | 0.104318 |
| NRG1 | neuregulin 1 | 0.0806034 |
| ENO1 | enolase 1, (alpha) | 0.0799669 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0603745 |
| PTCHD4 | patched domain containing 4 | 0.0597863 |
| SMYD3 | SET and MYND domain containing 3 | 0.0587121 |
| RPS3 | ribosomal protein S3 | 0.058067 |
| KCNB2 | potassium channel, voltage gated Shab related subfamily B, member 2 | 0.0546073 |
| CACNA1D | calcium channel, voltage-dependent, L type, alpha 1D subunit | 0.0537325 |
| NBEA | neurobeachin | 0.0511101 |
| MAP1B | microtubule-associated protein 1B | 0.0493515 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.0481078 |
| KCND2 | potassium channel, voltage gated Shal related subfamily D, member 2 | 0.0469114 |
| GPC5 | glypican 5 | 0.0458891 |
| TMSB4X | thymosin beta 4, X-linked | 0.0446827 |
| PEX5L | peroxisomal biogenesis factor 5-like | 0.0413279 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0406403 |
| ASCL1 | achaete-scute family bHLH transcription factor 1 | 0.0404387 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0402685 |
| CHGA | chromogranin A | 0.0401136 |
| TSHZ2 | teashirt zinc finger homeobox 2 | 0.0398186 |
| EFNA5 | ephrin-A5 | 0.0386805 |
| RIT2 | Ras-like without CAAX 2 | 0.0373106 |
| INHBA | inhibin, beta A | 0.0369682 |
| PCDH9 | protocadherin 9 | 0.0359232 |
| NSMCE2 | non-SMC element 2, MMS21 homolog (S. cerevisiae) | 0.0354661 |
| NKAIN2 | Na+/K+ transporting ATPase interacting 2 | 0.0351276 |
| SCG3 | secretogranin III | 0.0349959 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0348447 |
| NPAS3 | neuronal PAS domain protein 3 | 0.0336366 |
| RACK1 | receptor for activated C kinase 1 | 0.0326999 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | 0.0317166 |
| RPL11 | ribosomal protein L11 | 0.031517 |
| IRS2 | insulin receptor substrate 2 | 0.0315113 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0307792 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.030728 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0304721 |
| RPLP0 | ribosomal protein, large, P0 | 0.0301388 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0300843 |
| LSAMP | limbic system-associated membrane protein | 0.0298424 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.0284118 |
| EYA2 | EYA transcriptional coactivator and phosphatase 2 | 0.0279756 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | 0.0274868 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0270195 |
| GRIK1 | glutamate receptor, ionotropic, kainate 1 | 0.026995 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0267713 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0265723 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0263228 |
| PAEP | progestagen-associated endometrial protein | 0.0261808 |
| RGS7 | regulator of G-protein signaling 7 | 0.025754 |
| CREB5 | cAMP responsive element binding protein 5 | 0.0257219 |
| PEG10 | paternally expressed 10 | 0.0256162 |
| KCNMB3 | potassium channel subfamily M regulatory beta subunit 3 | 0.0252676 |
| HMGB3 | high mobility group box 3 | 0.0251965 |
| NSUN6 | NOP2/Sun domain family, member 6 | 0.0251658 |
| DACH1 | dachshund family transcription factor 1 | 0.0248201 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | 0.0247226 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0243263 |
| CNTNAP5 | contactin associated protein-like 5 | 0.0240856 |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | 0.0240522 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0239922 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0235482 |
| SNTG1 | syntrophin, gamma 1 | 0.0235385 |
| DST | dystonin | 0.0234617 |
| RPS12 | ribosomal protein S12 | 0.0233194 |
| EPHA6 | EPH receptor A6 | 0.0232951 |
| F2RL3 | coagulation factor II (thrombin) receptor-like 3 | 0.0231614 |
| KIAA0825 | KIAA0825 | 0.0231545 |
| ADARB2 | adenosine deaminase, RNA-specific, B2 (non-functional) | 0.0231003 |
| DENND4A | DENN/MADD domain containing 4A | 0.0229986 |
| SCG2 | secretogranin II | 0.0229283 |
| TCF12 | transcription factor 12 | 0.0229146 |
| CALCA | calcitonin-related polypeptide alpha | 0.0229027 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | 0.0227732 |
| ARHGAP9 | Rho GTPase activating protein 9 | 0.022769 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.02254 |
| RPS21 | ribosomal protein S21 | 0.0223613 |
| ST18 | suppression of tumorigenicity 18, zinc finger | 0.0223587 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | 0.022357 |
| RDX | radixin | 0.0221664 |
| SLC35F4 | solute carrier family 35, member F4 | 0.0219557 |
| YME1L1 | YME1-like 1 ATPase | 0.021761 |
| DGKB | diacylglycerol kinase, beta 90kDa | 0.0216642 |
| DCAF13 | DDB1 and CUL4 associated factor 13 | 0.0216184 |
| RPS27 | ribosomal protein S27 | 0.0214832 |
| SUPT16H | suppressor of Ty 16 homolog (S. cerevisiae) | 0.0213718 |
| CARD18 | caspase recruitment domain family, member 18 | 0.0213529 |
| SVIL | supervillin | 0.0211194 |
| ZBTB7C | zinc finger and BTB domain containing 7C | 0.0208183 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.020779 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | 0.0206334 |
| VPS13C | vacuolar protein sorting 13 homolog C (S. cerevisiae) | 0.020553 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0204547 |
| IMMT | inner membrane protein, mitochondrial | 0.020267 |
| TOX | thymocyte selection-associated high mobility group box | 0.0200935 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0196982 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE10A | phosphodiesterase 10A | -0.121428 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0847386 |
| PTMA | prothymosin, alpha | -0.0750298 |
| TENM1 | teneurin transmembrane protein 1 | -0.0658589 |
| VGF | VGF nerve growth factor inducible | -0.0622483 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0613665 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0610279 |
| SNAP25 | synaptosomal-associated protein, 25kDa | -0.0483807 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0423916 |
| RPS25 | ribosomal protein S25 | -0.0389829 |
| RPLP1 | ribosomal protein, large, P1 | -0.0369864 |
| RBM39 | RNA binding motif protein 39 | -0.0355277 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0347151 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0334003 |
| MCL1 | myeloid cell leukemia 1 | -0.0333786 |
| TFCP2 | transcription factor CP2 | -0.0332759 |
| CDK8 | cyclin-dependent kinase 8 | -0.033115 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0321233 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.032027 |
| IGF2 | insulin-like growth factor 2 | -0.031801 |
| SEPTIN7 | septin 7 | -0.0317622 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | -0.0308764 |
| FTL | ferritin, light polypeptide | -0.0303848 |
| TPR | translocated promoter region, nuclear basket protein | -0.0303746 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0302512 |
| MED13L | mediator complex subunit 13-like | -0.0299043 |
| RPS6 | ribosomal protein S6 | -0.0294256 |
| DENND1A | DENN/MADD domain containing 1A | -0.0294084 |
| AFF1 | AF4/FMR2 family, member 1 | -0.0290454 |
| PHIP | pleckstrin homology domain interacting protein | -0.0284417 |
| CCT6A | chaperonin containing TCP1, subunit 6A (zeta 1) | -0.0281409 |
| RPS20 | ribosomal protein S20 | -0.0276966 |
| CA8 | carbonic anhydrase VIII | -0.0275223 |
| RAN | RAN, member RAS oncogene family | -0.0274449 |
| PIAS2 | protein inhibitor of activated STAT, 2 | -0.0272063 |
| PCBP3 | poly(rC) binding protein 3 | -0.0268677 |
| GNAS | GNAS complex locus | -0.0265872 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | -0.026291 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0261171 |
| NCAM1 | neural cell adhesion molecule 1 | -0.0260329 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0260287 |
| FOXK1 | forkhead box K1 | -0.0258936 |
| RPL38 | ribosomal protein L38 | -0.0253462 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0250842 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0248644 |
| FUS | FUS RNA binding protein | -0.0245798 |
| RPS10 | ribosomal protein S10 | -0.0243398 |
| RPS23 | ribosomal protein S23 | -0.0243257 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0240694 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0237434 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0235983 |
| VAV2 | vav 2 guanine nucleotide exchange factor | -0.0235841 |
| NRDC | nardilysin convertase | -0.023568 |
| BPTF | bromodomain PHD finger transcription factor | -0.0235496 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0234814 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0234149 |
| ATF6 | activating transcription factor 6 | -0.0233081 |
| HELZ | helicase with zinc finger | -0.023207 |
| TTLL10 | tubulin tyrosine ligase-like family member 10 | -0.0230172 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | -0.0229954 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0229324 |
| RPLP2 | ribosomal protein, large, P2 | -0.0228827 |
| MKI67 | marker of proliferation Ki-67 | -0.0227843 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0225221 |
| SNX13 | sorting nexin 13 | -0.0223741 |
| RPL37A | ribosomal protein L37a | -0.0222153 |
| CUL3 | cullin 3 | -0.0221866 |
| AGO3 | argonaute RISC catalytic component 3 | -0.0221583 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.0220626 |
| SETX | senataxin | -0.0219987 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.0219385 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0218446 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0218414 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0218184 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0218068 |
| RHEB | Ras homolog enriched in brain | -0.0215318 |
| RRBP1 | ribosome binding protein 1 | -0.0214261 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | -0.0213753 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0212288 |
| PDS5B | PDS5 cohesin associated factor B | -0.0210659 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | -0.0209871 |
| MSI2 | musashi RNA-binding protein 2 | -0.0207719 |
| KDM6A | lysine (K)-specific demethylase 6A | -0.0206802 |
| STRBP | spermatid perinuclear RNA binding protein | -0.0206144 |
| BDP1 | B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB | -0.020551 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0205307 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0202436 |
| EP400 | E1A binding protein p400 | -0.020164 |
| RPL19 | ribosomal protein L19 | -0.0201317 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0201063 |
| HDAC8 | histone deacetylase 8 | -0.0200555 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.0199076 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0198794 |
| RSRC1 | arginine/serine-rich coiled-coil 1 | -0.0198441 |
| RPS17 | ribosomal protein S17 | -0.0198099 |
| RAB22A | RAB22A, member RAS oncogene family | -0.0197738 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.019714 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0196835 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | -0.0196534 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0196155 |
