| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | 18β-Glycyrrhetinic acid perturbation in SK-MEL-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the 18β-Glycyrrhetinic acid_SK-MEL-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.164076 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.157368 |
| NLGN1 | neuroligin 1 | 0.13071 |
| B2M | beta-2-microglobulin | 0.0809644 |
| NRG3 | neuregulin 3 | 0.0803867 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0655129 |
| RPS3 | ribosomal protein S3 | 0.0628568 |
| RAD51B | RAD51 paralog B | 0.0608521 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0607138 |
| LSAMP | limbic system-associated membrane protein | 0.0606183 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0604112 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0599246 |
| RPS6 | ribosomal protein S6 | 0.059107 |
| ANGPTL4 | angiopoietin-like 4 | 0.058475 |
| CBX3 | chromobox homolog 3 | 0.0576917 |
| RPS12 | ribosomal protein S12 | 0.0478349 |
| SFTPA2 | surfactant protein A2 | 0.0471174 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0448552 |
| HLA-A | major histocompatibility complex, class I, A | 0.0443052 |
| IFI44L | interferon-induced protein 44-like | 0.0434831 |
| MT2A | metallothionein 2A | 0.0434334 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0428784 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | 0.0406028 |
| RPL37A | ribosomal protein L37a | 0.0384538 |
| CDK6 | cyclin-dependent kinase 6 | 0.0379182 |
| FTL | ferritin, light polypeptide | 0.0376825 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0376518 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0372411 |
| DST | dystonin | 0.0370404 |
| TMSB10 | thymosin beta 10 | 0.0370253 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0363458 |
| MSN | moesin | 0.0359656 |
| RPL35A | ribosomal protein L35a | 0.0355713 |
| CYB5R3 | cytochrome b5 reductase 3 | 0.0349478 |
| RPL11 | ribosomal protein L11 | 0.0349228 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0346602 |
| TAGLN2 | transgelin 2 | 0.0333866 |
| SP100 | SP100 nuclear antigen | 0.0330587 |
| SOX10 | SRY (sex determining region Y)-box 10 | 0.0323887 |
| VEGFA | vascular endothelial growth factor A | 0.0314847 |
| RNF213 | ring finger protein 213 | 0.0312488 |
| RPL31 | ribosomal protein L31 | 0.0312291 |
| RPS14 | ribosomal protein S14 | 0.0311421 |
| IFITM3 | interferon induced transmembrane protein 3 | 0.0311247 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0308797 |
| RPL27 | ribosomal protein L27 | 0.0303938 |
| TPI1 | triosephosphate isomerase 1 | 0.0293163 |
| RPS19 | ribosomal protein S19 | 0.0293005 |
| RPL36 | ribosomal protein L36 | 0.0289887 |
| RPL23 | ribosomal protein L23 | 0.0288439 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | 0.0285887 |
| CFAP20DC | CFAP20 domain containing | 0.0283108 |
| POTEF | POTE ankyrin domain family, member F | 0.0282371 |
| JMJD1C | jumonji domain containing 1C | 0.0282066 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0280443 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0279249 |
| HLA-B | major histocompatibility complex, class I, B | 0.0272096 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.0266621 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0265575 |
| LDHA | lactate dehydrogenase A | 0.0265197 |
| S100A9 | S100 calcium binding protein A9 | 0.0265173 |
| FHIT | fragile histidine triad | 0.0264893 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0261318 |
| ASPH | aspartate beta-hydroxylase | 0.0257231 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | 0.0256224 |
| CADM1 | cell adhesion molecule 1 | 0.0250853 |
| LEF1 | lymphoid enhancer-binding factor 1 | 0.0250376 |
| FGGY | FGGY carbohydrate kinase domain containing | 0.0247222 |
| RPS4X | ribosomal protein S4, X-linked | 0.0245413 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0244003 |
| PRAME | preferentially expressed antigen in melanoma | 0.0241704 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0241187 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0240086 |
| PA2G4 | proliferation-associated 2G4, 38kDa | 0.0238132 |
| SON | SON DNA binding protein | 0.023518 |
| RPL9 | ribosomal protein L9 | 0.0234026 |
| CNKSR3 | CNKSR family member 3 | 0.0230404 |
| PHF14 | PHD finger protein 14 | 0.0226215 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.0224552 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0219115 |
| PTMA | prothymosin, alpha | 0.0218441 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.021447 |
| ARPC1B | actin related protein 2/3 complex, subunit 1B, 41kDa | 0.021416 |
| ZNF462 | zinc finger protein 462 | 0.0213164 |
| NRP2 | neuropilin 2 | 0.0212938 |
| RPS17 | ribosomal protein S17 | 0.0212778 |
| PTK2 | protein tyrosine kinase 2 | 0.0212155 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0211858 |
| PHF21A | PHD finger protein 21A | 0.0210474 |
| DPY19L1 | dpy-19-like 1 (C. elegans) | 0.0208842 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | 0.0207197 |
| HMGA1 | high mobility group AT-hook 1 | 0.0206271 |
| RPL37 | ribosomal protein L37 | 0.0205622 |
| RPLP2 | ribosomal protein, large, P2 | 0.0205606 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0202896 |
| GRID2 | glutamate receptor, ionotropic, delta 2 | 0.0202549 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0201301 |
| FOXP1 | forkhead box P1 | 0.0200975 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | 0.0200444 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0199077 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.296243 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.143546 |
| UBC | ubiquitin C | -0.120013 |
| CANX | calnexin | -0.0957294 |
| FMN1 | formin 1 | -0.0813616 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0774631 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.0754143 |
| TXNRD1 | thioredoxin reductase 1 | -0.07251 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | -0.0677622 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0623722 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0586977 |
| SQSTM1 | sequestosome 1 | -0.0544818 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0519525 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0518846 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0516785 |
| GOLGA4 | golgin A4 | -0.0492952 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.047878 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0463094 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0458871 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0440733 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | -0.042356 |
| SPAG9 | sperm associated antigen 9 | -0.0421344 |
| CALU | calumenin | -0.0419268 |
| ACTG1 | actin gamma 1 | -0.0414307 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0392351 |
| MAP4 | microtubule-associated protein 4 | -0.0389194 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0387281 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0387265 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0381199 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0379316 |
| OXSR1 | oxidative stress responsive 1 | -0.0374688 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0362797 |
| EMP1 | epithelial membrane protein 1 | -0.0357941 |
| EP300 | E1A binding protein p300 | -0.0357255 |
| ANLN | anillin, actin binding protein | -0.0351067 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.034924 |
| NAV2 | neuron navigator 2 | -0.0346493 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0341992 |
| CALR | calreticulin | -0.0341716 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0338953 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0335725 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0334695 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0325144 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0321318 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.0320109 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | -0.0317613 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0317478 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0315424 |
| XRCC6 | X-ray repair complementing defective repair in Chinese hamster cells 6 | -0.0314552 |
| VIM | vimentin | -0.0313051 |
| HDLBP | high density lipoprotein binding protein | -0.031125 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | -0.0305867 |
| RPS27A | ribosomal protein S27a | -0.0304814 |
| TPM3 | tropomyosin 3 | -0.0298324 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0296019 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0293935 |
| OGA | O-GlcNAcase | -0.0292901 |
| STK10 | serine/threonine kinase 10 | -0.0288741 |
| TCF20 | transcription factor 20 (AR1) | -0.0286449 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -0.0285108 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0281286 |
| RAD21 | RAD21 homolog (S. pombe) | -0.028043 |
| ERBIN | erbb2 interacting protein | -0.0279789 |
| PUM2 | pumilio RNA-binding family member 2 | -0.027687 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0275387 |
| AHNAK | AHNAK nucleoprotein | -0.027392 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0273462 |
| CLINT1 | clathrin interactor 1 | -0.0273242 |
| RBM39 | RNA binding motif protein 39 | -0.0271755 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0267235 |
| ANXA2 | annexin A2 | -0.0264888 |
| IFRD1 | interferon-related developmental regulator 1 | -0.0263637 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0263594 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0260533 |
| COG5 | component of oligomeric golgi complex 5 | -0.0259163 |
| STK4 | serine/threonine kinase 4 | -0.0258858 |
| GOLGB1 | golgin B1 | -0.0258587 |
| FAM13B | family with sequence similarity 13, member B | -0.0257136 |
| LAMP2 | lysosomal-associated membrane protein 2 | -0.0255878 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 | -0.0255207 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0255119 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0253134 |
| RHOA | ras homolog family member A | -0.0249726 |
| FLNA | filamin A, alpha | -0.0249491 |
| NF1 | neurofibromin 1 | -0.0248771 |
| FBXL2 | F-box and leucine-rich repeat protein 2 | -0.0246833 |
| TPTEP2-CSNK1E | TPTEP2-CSNK1E readthrough | -0.0246154 |
| CLIC4 | chloride intracellular channel 4 | -0.0245475 |
| RASAL2 | RAS protein activator like 2 | -0.0237431 |
| ADAM17 | ADAM metallopeptidase domain 17 | -0.0235047 |
| FOXJ3 | forkhead box J3 | -0.0233748 |
| DENND4A | DENN/MADD domain containing 4A | -0.0233153 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0232278 |
| TFG | TRK-fused gene | -0.0231935 |
| CD44 | CD44 molecule (Indian blood group) | -0.0231584 |
| RPL4 | ribosomal protein L4 | -0.0230871 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.02304 |
| VMP1 | vacuole membrane protein 1 | -0.0229342 |
| PRELID2 | PRELI domain containing 2 | -0.022811 |
| RLF | rearranged L-myc fusion | -0.0228071 |
