| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | 18β-Glycyrrhetinic acid perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the 18β-Glycyrrhetinic acid_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.107937 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0961145 |
| MT2A | metallothionein 2A | 0.070305 |
| DUSP4 | dual specificity phosphatase 4 | 0.0664215 |
| HDAC9 | histone deacetylase 9 | 0.0641063 |
| RPL12 | ribosomal protein L12 | 0.0577113 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0551213 |
| RPL18 | ribosomal protein L18 | 0.0544936 |
| HSPB1 | heat shock 27kDa protein 1 | 0.049747 |
| S100A6 | S100 calcium binding protein A6 | 0.0477714 |
| B2M | beta-2-microglobulin | 0.0466384 |
| NSMCE2 | non-SMC element 2, MMS21 homolog (S. cerevisiae) | 0.041209 |
| RPS3 | ribosomal protein S3 | 0.0406785 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0399266 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0396104 |
| PDGFC | platelet derived growth factor C | 0.0391814 |
| SMC3 | structural maintenance of chromosomes 3 | 0.0385147 |
| RPL23 | ribosomal protein L23 | 0.0381646 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | 0.0381569 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0370568 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0368187 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0360046 |
| PTMA | prothymosin, alpha | 0.0356262 |
| XKR6 | XK, Kell blood group complex subunit-related family, member 6 | 0.0353531 |
| HMGA1 | high mobility group AT-hook 1 | 0.0353043 |
| EGFR | epidermal growth factor receptor | 0.0351968 |
| PRDX2 | peroxiredoxin 2 | 0.034772 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.034558 |
| TMEM41B | transmembrane protein 41B | 0.0335375 |
| RPS12 | ribosomal protein S12 | 0.0335219 |
| ECT2 | epithelial cell transforming 2 | 0.0323915 |
| FTL | ferritin, light polypeptide | 0.0323127 |
| TJP1 | tight junction protein 1 | 0.0320458 |
| PKM | pyruvate kinase, muscle | 0.0319303 |
| TUBB4B | tubulin, beta 4B class IVb | 0.0318891 |
| CNOT6L | CCR4-NOT transcription complex, subunit 6-like | 0.0318515 |
| BRD2 | bromodomain containing 2 | 0.0315543 |
| TPI1 | triosephosphate isomerase 1 | 0.0314879 |
| LDHA | lactate dehydrogenase A | 0.0306872 |
| CKAP2 | cytoskeleton associated protein 2 | 0.030541 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0294435 |
| PCBP2 | poly(rC) binding protein 2 | 0.0293545 |
| TACC2 | transforming, acidic coiled-coil containing protein 2 | 0.029295 |
| DUSP6 | dual specificity phosphatase 6 | 0.0292445 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0286683 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0285428 |
| LOXL3 | lysyl oxidase-like 3 | 0.0271737 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0268129 |
| AHCYL2 | adenosylhomocysteinase-like 2 | 0.0267356 |
| RPLP2 | ribosomal protein, large, P2 | 0.0267117 |
| GCLM | glutamate-cysteine ligase, modifier subunit | 0.0266192 |
| RACK1 | receptor for activated C kinase 1 | 0.0263759 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0263377 |
| U2SURP | U2 snRNP-associated SURP domain containing | 0.0263079 |
| SON | SON DNA binding protein | 0.0259935 |
| ATF4 | activating transcription factor 4 | 0.0257411 |
| NSD1 | nuclear receptor binding SET domain protein 1 | 0.0257262 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | 0.0256539 |
| RPL28 | ribosomal protein L28 | 0.0252851 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0247421 |
| KIF5B | kinesin family member 5B | 0.0246143 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0245826 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0244821 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0243639 |
| MATR3 | matrin 3 | 0.024303 |
| DHX36 | DEAH (Asp-Glu-Ala-His) box polypeptide 36 | 0.0242143 |
| TAGLN2 | transgelin 2 | 0.0237649 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0236398 |
| RAB27B | RAB27B, member RAS oncogene family | 0.0236268 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0235253 |
| RBM25 | RNA binding motif protein 25 | 0.0233911 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0231874 |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) | 0.0231399 |
| RNF145 | ring finger protein 145 | 0.0229751 |
| LDHB | lactate dehydrogenase B | 0.0225826 |
| IWS1 | IWS1 homolog (S. cerevisiae) | 0.0224285 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0222916 |
| NUCB2 | nucleobindin 2 | 0.0220208 |
| CENPF | centromere protein F, 350/400kDa | 0.0219351 |
| TXNIP | thioredoxin interacting protein | 0.0218094 |
| RFX3 | regulatory factor X, 3 (influences HLA class II expression) | 0.0217072 |
| ATP5F1E | ATP synthase F1 subunit epsilon | 0.0214862 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0213665 |
| XRN1 | 5'-3' exoribonuclease 1 | 0.0209587 |
| SCD5 | stearoyl-CoA desaturase 5 | 0.0208877 |
| FAM91A1 | family with sequence similarity 91, member A1 | 0.0205771 |
| NFIX | nuclear factor I/X (CCAAT-binding transcription factor) | 0.0204882 |
| ZNF644 | zinc finger protein 644 | 0.0204323 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0203988 |
| KDELR1 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 | 0.020248 |
| ANXA3 | annexin A3 | 0.0201821 |
| RDX | radixin | 0.0200368 |
| TFAP2A | transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) | 0.0200285 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | 0.0199035 |
| GPX4 | glutathione peroxidase 4 | 0.0198653 |
| MIER1 | mesoderm induction early response 1, transcriptional regulator | 0.0198062 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | 0.0197943 |
| SCFD1 | sec1 family domain containing 1 | 0.0197484 |
| CNOT7 | CCR4-NOT transcription complex, subunit 7 | 0.0197417 |
| UTY | ubiquitously transcribed tetratricopeptide repeat containing, Y-linked | 0.019741 |
| Symbol | Name | Standardized Value |
|---|---|---|
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.122369 |
| TMSB4X | thymosin beta 4, X-linked | -0.102855 |
| AHNAK | AHNAK nucleoprotein | -0.0779103 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.0755346 |
| VCL | vinculin | -0.0709248 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0695389 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0670954 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.0648957 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.0623763 |
| VIM | vimentin | -0.0618833 |
| EXT1 | exostosin glycosyltransferase 1 | -0.060883 |
| EML4 | echinoderm microtubule associated protein like 4 | -0.0599879 |
| RPL35A | ribosomal protein L35a | -0.0580467 |
| CAMKMT | calmodulin-lysine N-methyltransferase | -0.0575319 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0557182 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0542048 |
| RPS23 | ribosomal protein S23 | -0.0536683 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0534421 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0514992 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0505058 |
| NFIA | nuclear factor I/A | -0.050313 |
| MAP4 | microtubule-associated protein 4 | -0.0483638 |
| RPS6 | ribosomal protein S6 | -0.0471129 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0467703 |
| FOXP1 | forkhead box P1 | -0.0465835 |
| PTK2 | protein tyrosine kinase 2 | -0.045934 |
| RBM39 | RNA binding motif protein 39 | -0.0449064 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0448698 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0446124 |
| SMYD3 | SET and MYND domain containing 3 | -0.0429816 |
| PDE10A | phosphodiesterase 10A | -0.0429348 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0429121 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0426552 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0421377 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0417064 |
| SETD2 | SET domain containing 2 | -0.0416641 |
| FHIT | fragile histidine triad | -0.0415705 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.041329 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0413179 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0402885 |
| TCF12 | transcription factor 12 | -0.040016 |
| NSD2 | nuclear receptor binding SET domain protein 2 | -0.0399069 |
| UNC13A | unc-13 homolog A (C. elegans) | -0.039845 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0391058 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0389339 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | -0.0385556 |
| TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b | -0.038504 |
| CANX | calnexin | -0.0381891 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0378959 |
| RPS25 | ribosomal protein S25 | -0.037865 |
| PHACTR4 | phosphatase and actin regulator 4 | -0.0363459 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 | -0.0354569 |
| HM13 | histocompatibility (minor) 13 | -0.0353744 |
| RPS27A | ribosomal protein S27a | -0.0353209 |
| WDR45B | WD repeat domain 45B | -0.0347992 |
| KANK1 | KN motif and ankyrin repeat domains 1 | -0.0347864 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0347147 |
| GLI3 | GLI family zinc finger 3 | -0.0346919 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.034514 |
| KDM4B | lysine (K)-specific demethylase 4B | -0.0345107 |
| APP | amyloid beta (A4) precursor protein | -0.0343944 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 | -0.0343023 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0339571 |
| FAT1 | FAT atypical cadherin 1 | -0.0337688 |
| FBXO11 | F-box protein 11 | -0.0334336 |
| GCNT1 | glucosaminyl (N-acetyl) transferase 1, core 2 | -0.0333729 |
| KAT6A | K(lysine) acetyltransferase 6A | -0.0333202 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.033181 |
| RPL13A | ribosomal protein L13a | -0.0329977 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0327672 |
| RYBP | RING1 and YY1 binding protein | -0.0318391 |
| SMAD3 | SMAD family member 3 | -0.0317758 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0314158 |
| TUT4 | terminal uridylyl transferase 4 | -0.0313512 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0313256 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0312615 |
| INTS6 | integrator complex subunit 6 | -0.0311327 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0310812 |
| ENOSF1 | enolase superfamily member 1 | -0.0306139 |
| SQSTM1 | sequestosome 1 | -0.0305537 |
| TLK1 | tousled-like kinase 1 | -0.0304392 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0303964 |
| TAOK1 | TAO kinase 1 | -0.0303265 |
| UBE2V1 | ubiquitin-conjugating enzyme E2 variant 1 | -0.0301335 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0300206 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0300139 |
| RPLP1 | ribosomal protein, large, P1 | -0.0298954 |
| ATG7 | autophagy related 7 | -0.0298766 |
| YEATS2 | YEATS domain containing 2 | -0.0298677 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0297634 |
| NF1 | neurofibromin 1 | -0.0296566 |
| AOPEP | aminopeptidase O (putative) | -0.0295394 |
| BMP2K | BMP2 inducible kinase | -0.029031 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0288974 |
| TPM4 | tropomyosin 4 | -0.0287848 |
| MYO5C | myosin VC | -0.0286553 |
| BPTF | bromodomain PHD finger transcription factor | -0.0286477 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0276537 |
| GLI2 | GLI family zinc finger 2 | -0.0274099 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0271121 |
