| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | 18β-Glycyrrhetinic acid perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the 18β-Glycyrrhetinic acid_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | 0.138488 |
| LDHA | lactate dehydrogenase A | 0.107817 |
| HLA-A | major histocompatibility complex, class I, A | 0.0861283 |
| RPS12 | ribosomal protein S12 | 0.0856459 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0850596 |
| B2M | beta-2-microglobulin | 0.0829063 |
| NAV2 | neuron navigator 2 | 0.0735181 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0702046 |
| NDRG1 | N-myc downstream regulated 1 | 0.0693066 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0639093 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0615216 |
| ADM | adrenomedullin | 0.0582011 |
| RPL37A | ribosomal protein L37a | 0.0578924 |
| RPS3 | ribosomal protein S3 | 0.0573435 |
| FTL | ferritin, light polypeptide | 0.0548043 |
| MYOF | myoferlin | 0.0535098 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0511356 |
| RPS4X | ribosomal protein S4, X-linked | 0.0495832 |
| ENO1 | enolase 1, (alpha) | 0.0485178 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0470373 |
| RACK1 | receptor for activated C kinase 1 | 0.0460071 |
| RPL23 | ribosomal protein L23 | 0.0453459 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0416619 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0403444 |
| KLF6 | Kruppel-like factor 6 | 0.0400518 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0377898 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0375885 |
| STC1 | stanniocalcin 1 | 0.0375348 |
| RPL12 | ribosomal protein L12 | 0.0367312 |
| BRD2 | bromodomain containing 2 | 0.0363892 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.035161 |
| GOLGA4 | golgin A4 | 0.0343338 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0325566 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0324497 |
| GPC6 | glypican 6 | 0.0323566 |
| RPS17 | ribosomal protein S17 | 0.0317686 |
| RPL37 | ribosomal protein L37 | 0.0315981 |
| RPL9 | ribosomal protein L9 | 0.0312443 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0307129 |
| SQSTM1 | sequestosome 1 | 0.0293122 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0292481 |
| LOX | lysyl oxidase | 0.028787 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0287261 |
| TMSB10 | thymosin beta 10 | 0.0277613 |
| RPL11 | ribosomal protein L11 | 0.0273339 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0272222 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0267062 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0266828 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.026509 |
| SPAG9 | sperm associated antigen 9 | 0.0261092 |
| INTS6 | integrator complex subunit 6 | 0.0257389 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0254141 |
| RPL36 | ribosomal protein L36 | 0.0250709 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.024549 |
| FMNL2 | formin-like 2 | 0.0242888 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0241743 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0240331 |
| RPS19 | ribosomal protein S19 | 0.0236532 |
| RPL30 | ribosomal protein L30 | 0.0236026 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0233325 |
| TRAM2 | translocation associated membrane protein 2 | 0.0231881 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0230897 |
| MORF4L2 | mortality factor 4 like 2 | 0.0229888 |
| MKI67 | marker of proliferation Ki-67 | 0.022937 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0228069 |
| HDAC9 | histone deacetylase 9 | 0.0227567 |
| LAMP2 | lysosomal-associated membrane protein 2 | 0.0227409 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0226176 |
| IRS2 | insulin receptor substrate 2 | 0.0224698 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0220794 |
| SERINC1 | serine incorporator 1 | 0.0217115 |
| ANGPTL4 | angiopoietin-like 4 | 0.0216859 |
| CD59 | CD59 molecule, complement regulatory protein | 0.0210366 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | 0.0209113 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0208667 |
| DNAJC8 | DnaJ (Hsp40) homolog, subfamily C, member 8 | 0.0207276 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0206638 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0205408 |
| SFTPA2 | surfactant protein A2 | 0.0201679 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0199855 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.019719 |
| CTSA | cathepsin A | 0.0196595 |
| RPS2 | ribosomal protein S2 | 0.0195271 |
| C6ORF62 | chromosome 6 open reading frame 62 | 0.0195255 |
| GADD45B | growth arrest and DNA-damage-inducible, beta | 0.019485 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0193831 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.01923 |
| OGA | O-GlcNAcase | 0.0192082 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.018937 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0187307 |
| ABCA5 | ATP-binding cassette, sub-family A (ABC1), member 5 | 0.0186234 |
| EGR1 | early growth response 1 | 0.0184724 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0183078 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | 0.018303 |
| RPLP0 | ribosomal protein, large, P0 | 0.0181757 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0180825 |
| AFDN | afadin, adherens junction formation factor | 0.0179839 |
| UST | uronyl-2-sulfotransferase | 0.0178334 |
| SLU7 | SLU7 splicing factor homolog (S. cerevisiae) | 0.0177766 |
| TMF1 | TATA element modulatory factor 1 | 0.0177114 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.141102 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.136492 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.136457 |
| FRMD4A | FERM domain containing 4A | -0.12746 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.127386 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.126713 |
| GLIS3 | GLIS family zinc finger 3 | -0.107022 |
| EXT1 | exostosin glycosyltransferase 1 | -0.106416 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0974589 |
| VIM | vimentin | -0.0937576 |
| TPM4 | tropomyosin 4 | -0.0914572 |
| RAI14 | retinoic acid induced 14 | -0.0737897 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | -0.0726479 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0713008 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0706761 |
| VCL | vinculin | -0.0672297 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.066393 |
| KYNU | kynureninase | -0.0655685 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0641989 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0639016 |
| PDE10A | phosphodiesterase 10A | -0.063005 |
| HLA-B | major histocompatibility complex, class I, B | -0.0619429 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0603253 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0572391 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0570362 |
| CDH13 | cadherin 13 | -0.0562745 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0552783 |
| COL1A1 | collagen, type I, alpha 1 | -0.0550614 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0547134 |
| IL6 | interleukin 6 | -0.0544089 |
| THBS1 | thrombospondin 1 | -0.0543713 |
| DIAPH2 | diaphanous-related formin 2 | -0.0542021 |
| SBF2 | SET binding factor 2 | -0.0538992 |
| ADAM12 | ADAM metallopeptidase domain 12 | -0.0538714 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.053156 |
| RIGI | RNA sensor RIG-I | -0.051933 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0511603 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0500355 |
| PHF21A | PHD finger protein 21A | -0.0491517 |
| TPM1 | tropomyosin 1 (alpha) | -0.0489761 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0485059 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.048243 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0482098 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | -0.0481705 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0475499 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0465527 |
| CLIC4 | chloride intracellular channel 4 | -0.0462546 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0460385 |
| CD44 | CD44 molecule (Indian blood group) | -0.0459421 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0457675 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0456403 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0453582 |
| NAV1 | neuron navigator 1 | -0.0450886 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0438674 |
| CLMP | CXADR-like membrane protein | -0.0436368 |
| ACTG1 | actin gamma 1 | -0.043574 |
| NABP1 | nucleic acid binding protein 1 | -0.0435428 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0419719 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0418242 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0414821 |
| RTN4 | reticulon 4 | -0.0413513 |
| COL1A2 | collagen, type I, alpha 2 | -0.0412928 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0410915 |
| NRP1 | neuropilin 1 | -0.0408185 |
| C3 | complement component 3 | -0.0401727 |
| XIAP | X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase | -0.0385095 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0378856 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0378022 |
| FLNB | filamin B, beta | -0.0374379 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0373877 |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) | -0.0370471 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0370093 |
| SAMHD1 | SAM domain and HD domain 1 | -0.0369176 |
| PTMA | prothymosin, alpha | -0.0368841 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | -0.0367979 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0367641 |
| PTK2 | protein tyrosine kinase 2 | -0.0361638 |
| TXNRD1 | thioredoxin reductase 1 | -0.0359251 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0358804 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0354932 |
| GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A | -0.0353874 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0351868 |
| DENND5B | DENN/MADD domain containing 5B | -0.0348361 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.034603 |
| CUX1 | cut-like homeobox 1 | -0.0345487 |
| MAP4 | microtubule-associated protein 4 | -0.0342485 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.0341868 |
| DENND5A | DENN/MADD domain containing 5A | -0.0340105 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0333918 |
| HMGA2 | high mobility group AT-hook 2 | -0.033236 |
| KIF13A | kinesin family member 13A | -0.0332196 |
| RNF213 | ring finger protein 213 | -0.0332117 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0328183 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0327189 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0325123 |
| RBFOX1 | RNA binding protein, fox-1 homolog (C. elegans) 1 | -0.0319456 |
| MX2 | MX dynamin-like GTPase 2 | -0.0318596 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0317339 |
| SCARB1 | scavenger receptor class B, member 1 | -0.0316965 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0315533 |
