| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | 18β-Glycyrrhetinic acid perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the 18β-Glycyrrhetinic acid_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.203999 |
| MT2A | metallothionein 2A | 0.135562 |
| PRSS23 | protease, serine, 23 | 0.0836498 |
| FN1 | fibronectin 1 | 0.0803466 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0796823 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0775101 |
| CD44 | CD44 molecule (Indian blood group) | 0.073695 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0703045 |
| NRXN3 | neurexin 3 | 0.068537 |
| VIM | vimentin | 0.0600557 |
| VEGFA | vascular endothelial growth factor A | 0.0597663 |
| IGF2 | insulin-like growth factor 2 | 0.0597096 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.059527 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0573315 |
| IGFBP7 | insulin-like growth factor binding protein 7 | 0.0571264 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0565685 |
| B2M | beta-2-microglobulin | 0.0556306 |
| CDH13 | cadherin 13 | 0.0554783 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.055163 |
| LOX | lysyl oxidase | 0.053937 |
| MAP1B | microtubule-associated protein 1B | 0.0521401 |
| EGFR | epidermal growth factor receptor | 0.0520182 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0507974 |
| EFNA5 | ephrin-A5 | 0.050424 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0503837 |
| HLA-A | major histocompatibility complex, class I, A | 0.0494945 |
| DST | dystonin | 0.047142 |
| RAD51B | RAD51 paralog B | 0.0460561 |
| HMGA2 | high mobility group AT-hook 2 | 0.0445856 |
| NDRG1 | N-myc downstream regulated 1 | 0.0443974 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0438051 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | 0.0437288 |
| HDAC9 | histone deacetylase 9 | 0.0436241 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0429368 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0428158 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0411677 |
| PRELID2 | PRELI domain containing 2 | 0.0390687 |
| MYOF | myoferlin | 0.0381803 |
| GSE1 | Gse1 coiled-coil protein | 0.0378179 |
| RPL26 | ribosomal protein L26 | 0.0364542 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0357123 |
| VCL | vinculin | 0.0355773 |
| ITGB3BP | integrin beta 3 binding protein (beta3-endonexin) | 0.0343753 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0341016 |
| RPL11 | ribosomal protein L11 | 0.0339724 |
| WWOX | WW domain containing oxidoreductase | 0.0339266 |
| ANXA2 | annexin A2 | 0.0337155 |
| MAF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog | 0.0336309 |
| THBS1 | thrombospondin 1 | 0.0329706 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0324325 |
| NKTR | natural killer cell triggering receptor | 0.0320288 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0319261 |
| RPS12 | ribosomal protein S12 | 0.0313715 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0309265 |
| FRMD4A | FERM domain containing 4A | 0.0305095 |
| JPH2 | junctophilin 2 | 0.0298068 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | 0.029614 |
| GLIS3 | GLIS family zinc finger 3 | 0.029427 |
| RPS19 | ribosomal protein S19 | 0.0291406 |
| TAGLN2 | transgelin 2 | 0.0288279 |
| CBX3 | chromobox homolog 3 | 0.0287749 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | 0.0286811 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0286213 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | 0.0285314 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | 0.0281773 |
| RNF145 | ring finger protein 145 | 0.0280716 |
| ANO6 | anoctamin 6 | 0.0275918 |
| UBXN4 | UBX domain protein 4 | 0.0271994 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.026964 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0269021 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0268354 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.0267604 |
| CDK6 | cyclin-dependent kinase 6 | 0.0267268 |
| LOXL2 | lysyl oxidase-like 2 | 0.0267012 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0265711 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0262466 |
| ASPH | aspartate beta-hydroxylase | 0.0262088 |
| SYNPO | synaptopodin | 0.0261379 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0255843 |
| GNAS | GNAS complex locus | 0.0250729 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | 0.0248332 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0247668 |
| ZNF644 | zinc finger protein 644 | 0.0245437 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | 0.0243769 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0243388 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0237853 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0237572 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0236445 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | 0.0235177 |
| PKM | pyruvate kinase, muscle | 0.02351 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0233533 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.0232838 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0232597 |
| BBS9 | Bardet-Biedl syndrome 9 | 0.0230791 |
| NECTIN3 | nectin cell adhesion molecule 3 | 0.0226889 |
| TPI1 | triosephosphate isomerase 1 | 0.0226627 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | 0.0226553 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0225718 |
| KAZN | kazrin, periplakin interacting protein | 0.0224913 |
| CA12 | carbonic anhydrase XII | 0.0224869 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.179779 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.113849 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.110851 |
| UBC | ubiquitin C | -0.0995925 |
| SDC4 | syndecan 4 | -0.0758824 |
| ANXA5 | annexin A5 | -0.0675206 |
| SPAG9 | sperm associated antigen 9 | -0.0607374 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0598563 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0522839 |
| HOOK2 | hook microtubule-tethering protein 2 | -0.0507269 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0483672 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0474893 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0474563 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0473741 |
| COL1A1 | collagen, type I, alpha 1 | -0.0467811 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | -0.0459347 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0436724 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0424936 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0423205 |
| CCNI | cyclin I | -0.0415712 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0413572 |
| TPM4 | tropomyosin 4 | -0.0394258 |
| PTMA | prothymosin, alpha | -0.0392798 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0389787 |
| COL1A2 | collagen, type I, alpha 2 | -0.0388192 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0387141 |
| JUN | jun proto-oncogene | -0.0376028 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.037318 |
| LONP2 | lon peptidase 2, peroxisomal | -0.0347743 |
| SEC24D | SEC24 family member D | -0.0342229 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0342192 |
| ZNF292 | zinc finger protein 292 | -0.0336381 |
| H3-3B | H3.3 histone B | -0.0332606 |
| GLG1 | golgi glycoprotein 1 | -0.0331734 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | -0.0328548 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0323112 |
| CALU | calumenin | -0.0321624 |
| TPM2 | tropomyosin 2 (beta) | -0.0316109 |
| WTAP | Wilms tumor 1 associated protein | -0.0315052 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0309224 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.030721 |
| ADM | adrenomedullin | -0.0306401 |
| SAR1A | secretion associated, Ras related GTPase 1A | -0.0306226 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0305714 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | -0.0305112 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0304464 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.0299281 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0293796 |
| GOLGA4 | golgin A4 | -0.0293763 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0292227 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0292021 |
| OGA | O-GlcNAcase | -0.0290135 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.028888 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0284288 |
| S100A10 | S100 calcium binding protein A10 | -0.0279138 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0276744 |
| TFG | TRK-fused gene | -0.0276067 |
| FLNB | filamin B, beta | -0.0274745 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | -0.0273526 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0272828 |
| TXNIP | thioredoxin interacting protein | -0.0272449 |
| TMEM41B | transmembrane protein 41B | -0.0268972 |
| CDK7 | cyclin-dependent kinase 7 | -0.0268809 |
| IL6ST | interleukin 6 signal transducer | -0.026742 |
| PRRC1 | proline-rich coiled-coil 1 | -0.0266493 |
| STK17A | serine/threonine kinase 17a | -0.026583 |
| CANX | calnexin | -0.0265432 |
| STC1 | stanniocalcin 1 | -0.0263287 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | -0.0260562 |
| SKP1 | S-phase kinase-associated protein 1 | -0.0259386 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | -0.0256024 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0255917 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0255039 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0254524 |
| AHNAK | AHNAK nucleoprotein | -0.0248697 |
| IFRD1 | interferon-related developmental regulator 1 | -0.0247324 |
| ZNF207 | zinc finger protein 207 | -0.0245432 |
| MTPN | myotrophin | -0.0245222 |
| ABI1 | abl-interactor 1 | -0.0243664 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | -0.0240827 |
| FNBP4 | formin binding protein 4 | -0.0234921 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0234334 |
| TBC1D23 | TBC1 domain family, member 23 | -0.0233233 |
| RTN4 | reticulon 4 | -0.0233149 |
| ERLEC1 | endoplasmic reticulum lectin 1 | -0.0232953 |
| ARHGAP10 | Rho GTPase activating protein 10 | -0.023281 |
| CRLS1 | cardiolipin synthase 1 | -0.0231979 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | -0.0228505 |
| CUL4B | cullin 4B | -0.0226544 |
| ACVR1 | activin A receptor, type I | -0.022607 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0225363 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0224354 |
| SRPK2 | SRSF protein kinase 2 | -0.0224344 |
| PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 | -0.0221801 |
| HMGB2 | high mobility group box 2 | -0.0220646 |
| HBP1 | HMG-box transcription factor 1 | -0.0218876 |
| RBM39 | RNA binding motif protein 39 | -0.0218511 |
| PNPLA8 | patatin-like phospholipase domain containing 8 | -0.0217758 |
| ITM2B | integral membrane protein 2B | -0.0217278 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0217253 |