| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | 18β-Glycyrrhetinic acid perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the 18β-Glycyrrhetinic acid_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.120349 |
| TMSB10 | thymosin beta 10 | 0.0921047 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.082698 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0771505 |
| ANGPTL4 | angiopoietin-like 4 | 0.0766015 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0704563 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0700567 |
| CD44 | CD44 molecule (Indian blood group) | 0.0700285 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0685031 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0642865 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0634902 |
| VIM | vimentin | 0.0624254 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0597201 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.058989 |
| FMNL2 | formin-like 2 | 0.0582691 |
| MT2A | metallothionein 2A | 0.0546875 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0532952 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.051976 |
| RORA | RAR-related orphan receptor A | 0.0519197 |
| LDHA | lactate dehydrogenase A | 0.0502961 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0492868 |
| ACTN1 | actinin, alpha 1 | 0.0477712 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0467254 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0448616 |
| GPC6 | glypican 6 | 0.044255 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0436709 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0436078 |
| NDRG1 | N-myc downstream regulated 1 | 0.0433749 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | 0.042546 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0418424 |
| NSD1 | nuclear receptor binding SET domain protein 1 | 0.0417625 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0416545 |
| DNER | delta/notch-like EGF repeat containing | 0.0407379 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0399064 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.0395851 |
| RPS12 | ribosomal protein S12 | 0.0395271 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0389732 |
| RNASEH2A | ribonuclease H2, subunit A | 0.038729 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | 0.0380561 |
| PGK1 | phosphoglycerate kinase 1 | 0.0377719 |
| RTN4 | reticulon 4 | 0.0376565 |
| KLF6 | Kruppel-like factor 6 | 0.0374846 |
| CDCP1 | CUB domain containing protein 1 | 0.0370911 |
| SLMAP | sarcolemma associated protein | 0.0367788 |
| ANO6 | anoctamin 6 | 0.0366776 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0362983 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0361576 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.035911 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0357139 |
| FLNB | filamin B, beta | 0.0353525 |
| ACTG1 | actin gamma 1 | 0.0352071 |
| CAVIN1 | caveolae associated protein 1 | 0.035109 |
| PRSS23 | protease, serine, 23 | 0.0349621 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0348896 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.0347638 |
| RNF24 | ring finger protein 24 | 0.0343749 |
| RASAL2 | RAS protein activator like 2 | 0.0341955 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0337417 |
| UBXN4 | UBX domain protein 4 | 0.0335728 |
| DARS1 | aspartyl-tRNA synthetase 1 | 0.0329817 |
| JMJD1C | jumonji domain containing 1C | 0.0327551 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0321664 |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase | 0.0319203 |
| TXNIP | thioredoxin interacting protein | 0.0310921 |
| MSN | moesin | 0.031055 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0309986 |
| DERA | deoxyribose-phosphate aldolase (putative) | 0.0304784 |
| CCDC88A | coiled-coil domain containing 88A | 0.0299462 |
| CCDC174 | coiled-coil domain containing 174 | 0.0297852 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.029692 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0294722 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.0294385 |
| KIF5B | kinesin family member 5B | 0.0293688 |
| EGR1 | early growth response 1 | 0.0290813 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0286821 |
| SEC62 | SEC62 homolog (S. cerevisiae) | 0.0285636 |
| AXL | AXL receptor tyrosine kinase | 0.028193 |
| WFDC10B | WAP four-disulfide core domain 10B | 0.0280442 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.028007 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0279552 |
| PODXL | podocalyxin-like | 0.0279056 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.0278646 |
| RAB27B | RAB27B, member RAS oncogene family | 0.0278527 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0277549 |
| AREG | amphiregulin | 0.0276976 |
| LIMA1 | LIM domain and actin binding 1 | 0.0276565 |
| KIAA1549L | KIAA1549-like | 0.027523 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0271294 |
| SMAD3 | SMAD family member 3 | 0.0268908 |
| RDX | radixin | 0.026681 |
| PLEK2 | pleckstrin 2 | 0.0266704 |
| CEP112 | centrosomal protein 112kDa | 0.0265052 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.0264822 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0263982 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.026175 |
| ATF4 | activating transcription factor 4 | 0.026054 |
| DOCK7 | dedicator of cytokinesis 7 | 0.0258378 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0258245 |
| TTC19 | tetratricopeptide repeat domain 19 | 0.0257753 |
| UBE3A | ubiquitin protein ligase E3A | 0.0257403 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.142756 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.101301 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.09583 |
| UBC | ubiquitin C | -0.0944203 |
| GNAS | GNAS complex locus | -0.0850928 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0809397 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0720185 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0718851 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0659141 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0629744 |
| SPAG9 | sperm associated antigen 9 | -0.0592479 |
| RBM39 | RNA binding motif protein 39 | -0.0588191 |
| CANX | calnexin | -0.0569632 |
| NUP58 | nucleoporin 58 | -0.052834 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0518304 |
| CALU | calumenin | -0.0498464 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0494967 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0481308 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.047744 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.046804 |
| PHIP | pleckstrin homology domain interacting protein | -0.0467995 |
| INTS6 | integrator complex subunit 6 | -0.0456995 |
| VPS13A | vacuolar protein sorting 13 homolog A (S. cerevisiae) | -0.0453439 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0441191 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.0439258 |
| RPL27A | ribosomal protein L27a | -0.0436935 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.043525 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0434939 |
| RPS27A | ribosomal protein S27a | -0.0429295 |
| TPX2 | TPX2, microtubule-associated | -0.0424185 |
| SRPK2 | SRSF protein kinase 2 | -0.04233 |
| RPS8 | ribosomal protein S8 | -0.0418646 |
| WDR45B | WD repeat domain 45B | -0.041545 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0405112 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0404102 |
| SAFB | scaffold attachment factor B | -0.040208 |
| DEK | DEK proto-oncogene | -0.0395358 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0391703 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0389087 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0379175 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0378534 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | -0.0378031 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0376847 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0376326 |
| EXOC6B | exocyst complex component 6B | -0.0372105 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0369083 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.0362535 |
| USP15 | ubiquitin specific peptidase 15 | -0.0360432 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0358356 |
| CHD1 | chromodomain helicase DNA binding protein 1 | -0.0355384 |
| SCFD1 | sec1 family domain containing 1 | -0.0352785 |
| CLIC4 | chloride intracellular channel 4 | -0.0350797 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0350718 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0343772 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | -0.0338842 |
| DIAPH3 | diaphanous-related formin 3 | -0.033781 |
| ADIPOR2 | adiponectin receptor 2 | -0.0334722 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0331628 |
| NAA35 | N(alpha)-acetyltransferase 35, NatC auxiliary subunit | -0.0330893 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0330024 |
| KIF4A | kinesin family member 4A | -0.0329785 |
| S100A9 | S100 calcium binding protein A9 | -0.0328554 |
| SNX14 | sorting nexin 14 | -0.0324569 |
| TAF1 | TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa | -0.0324408 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0324105 |
| CHSY1 | chondroitin sulfate synthase 1 | -0.0322157 |
| RPL37 | ribosomal protein L37 | -0.032075 |
| RABGAP1 | RAB GTPase activating protein 1 | -0.0317725 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0317535 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0315302 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0313845 |
| TRIM37 | tripartite motif containing 37 | -0.0311493 |
| DDX46 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 | -0.0309155 |
| RPL19 | ribosomal protein L19 | -0.0308435 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0307622 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0306239 |
| PCBP2 | poly(rC) binding protein 2 | -0.0304498 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0296779 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0291286 |
| CEP250 | centrosomal protein 250kDa | -0.0291048 |
| NUP160 | nucleoporin 160kDa | -0.0287874 |
| PEAK1 | pseudopodium-enriched atypical kinase 1 | -0.0285652 |
| RPL5 | ribosomal protein L5 | -0.0284183 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0282469 |
| GOLGA3 | golgin A3 | -0.02808 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | -0.0278513 |
| CELF1 | CUGBP, Elav-like family member 1 | -0.0278046 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0277703 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | -0.0277564 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | -0.0277266 |
| UBE2K | ubiquitin-conjugating enzyme E2K | -0.0276688 |
| SMARCA5 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 | -0.0276672 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0276629 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0276283 |
| RNF111 | ring finger protein 111 | -0.0275723 |
| RPL37A | ribosomal protein L37a | -0.0272798 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0272662 |
| SUN1 | Sad1 and UNC84 domain containing 1 | -0.0270459 |
| RIGI | RNA sensor RIG-I | -0.0269106 |
| FBXO34 | F-box protein 34 | -0.0268129 |
