| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | 18β-Glycyrrhetinic acid perturbation in SW1417 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the 18β-Glycyrrhetinic acid_SW1417 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FTL | ferritin, light polypeptide | 0.232891 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.126536 |
| RPL12 | ribosomal protein L12 | 0.123652 |
| RPL23 | ribosomal protein L23 | 0.0981245 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0974389 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0890206 |
| B2M | beta-2-microglobulin | 0.0876788 |
| RPS3 | ribosomal protein S3 | 0.0846242 |
| RPS12 | ribosomal protein S12 | 0.0835375 |
| RPS19 | ribosomal protein S19 | 0.0800807 |
| RPL18 | ribosomal protein L18 | 0.0765793 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0719576 |
| NEBL | nebulette | 0.062672 |
| RPL37A | ribosomal protein L37a | 0.0625219 |
| EPCAM | epithelial cell adhesion molecule | 0.0583059 |
| HLA-A | major histocompatibility complex, class I, A | 0.057541 |
| RPS6 | ribosomal protein S6 | 0.0573548 |
| MYO1E | myosin IE | 0.0567576 |
| LDHA | lactate dehydrogenase A | 0.0549403 |
| RACK1 | receptor for activated C kinase 1 | 0.0535172 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0522632 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.0518201 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0517572 |
| STT3B | STT3B, subunit of the oligosaccharyltransferase complex (catalytic) | 0.0512769 |
| GOLGA4 | golgin A4 | 0.0504984 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0502174 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0485407 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0481024 |
| EGFR | epidermal growth factor receptor | 0.0437999 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0434875 |
| LOC112694756 | uncharaterized LOC112694756 | 0.04314 |
| MYOF | myoferlin | 0.0424504 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0417681 |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 | 0.0405322 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.040321 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0402034 |
| EDN1 | endothelin 1 | 0.0390337 |
| RPS17 | ribosomal protein S17 | 0.0383866 |
| RPL11 | ribosomal protein L11 | 0.0376666 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0371035 |
| RPL36 | ribosomal protein L36 | 0.037064 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0368613 |
| RPL26 | ribosomal protein L26 | 0.036756 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0367237 |
| WWC1 | WW and C2 domain containing 1 | 0.0360387 |
| ATP5F1E | ATP synthase F1 subunit epsilon | 0.0359458 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0356104 |
| TES | testin LIM domain protein | 0.0355228 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0354607 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0346008 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0344853 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0341366 |
| RPL31 | ribosomal protein L31 | 0.0337982 |
| TJP1 | tight junction protein 1 | 0.0336775 |
| KDELR1 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 | 0.0327768 |
| IFITM1 | interferon induced transmembrane protein 1 | 0.0320635 |
| RPLP0 | ribosomal protein, large, P0 | 0.0318514 |
| RPS26 | ribosomal protein S26 | 0.0317483 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0313306 |
| TPI1 | triosephosphate isomerase 1 | 0.0308054 |
| RPS5 | ribosomal protein S5 | 0.0306451 |
| AFDN | afadin, adherens junction formation factor | 0.0305004 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0301187 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0299228 |
| TMF1 | TATA element modulatory factor 1 | 0.0298788 |
| COX6C | cytochrome c oxidase subunit VIc | 0.0297932 |
| SMAD2 | SMAD family member 2 | 0.0297925 |
| VCL | vinculin | 0.0297102 |
| GPHN | gephyrin | 0.0296439 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0294042 |
| TMSB4X | thymosin beta 4, X-linked | 0.0293282 |
| RPL9 | ribosomal protein L9 | 0.0292197 |
| RPS14 | ribosomal protein S14 | 0.0291385 |
| EIF5B | eukaryotic translation initiation factor 5B | 0.0289403 |
| TGFA | transforming growth factor, alpha | 0.0286785 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0286542 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.02852 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0285036 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.02835 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0277929 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0277357 |
| SON | SON DNA binding protein | 0.0275099 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0275094 |
| CLDN4 | claudin 4 | 0.0274413 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0265928 |
| ROMO1 | reactive oxygen species modulator 1 | 0.0261972 |
| SMAD3 | SMAD family member 3 | 0.0260873 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0260833 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0259197 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0256482 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | 0.0255761 |
| IFITM3 | interferon induced transmembrane protein 3 | 0.0255115 |
| RPLP1 | ribosomal protein, large, P1 | 0.0250795 |
| TUBB4B | tubulin, beta 4B class IVb | 0.025078 |
| SLC25A3 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 | 0.0246193 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.0244019 |
| GPX4 | glutathione peroxidase 4 | 0.0243589 |
| CLTC | clathrin, heavy chain (Hc) | 0.0241369 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0240801 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0239008 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.232317 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.145691 |
| UBC | ubiquitin C | -0.11377 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.103052 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0985123 |
| KRT8 | keratin 8, type II | -0.097197 |
| TMEM123 | transmembrane protein 123 | -0.0715884 |
| PKM | pyruvate kinase, muscle | -0.0652465 |
| ACTN4 | actinin, alpha 4 | -0.0644321 |
| RBM39 | RNA binding motif protein 39 | -0.0577612 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0570124 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0563186 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.0529475 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0505621 |
| IFRD1 | interferon-related developmental regulator 1 | -0.0489083 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0481919 |
| S100A6 | S100 calcium binding protein A6 | -0.0474608 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0465551 |
| SRPK2 | SRSF protein kinase 2 | -0.0464495 |
| TPM4 | tropomyosin 4 | -0.0448776 |
| AHNAK | AHNAK nucleoprotein | -0.0442176 |
| CCND1 | cyclin D1 | -0.0431645 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0426719 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | -0.0418897 |
| GTF2IRD1 | GTF2I repeat domain containing 1 | -0.0415891 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0406984 |
| SETD5 | SET domain containing 5 | -0.040352 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0394469 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0393387 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0389536 |
| S100A10 | S100 calcium binding protein A10 | -0.0389031 |
| RPS13 | ribosomal protein S13 | -0.0385171 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0376919 |
| CADPS | Ca++-dependent secretion activator | -0.0376593 |
| RPS27A | ribosomal protein S27a | -0.0373819 |
| ANO1 | anoctamin 1, calcium activated chloride channel | -0.0371176 |
| FRMD5 | FERM domain containing 5 | -0.0371164 |
| SDC4 | syndecan 4 | -0.036024 |
| TMSB10 | thymosin beta 10 | -0.0353571 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0352677 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0352606 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.0349448 |
| SQSTM1 | sequestosome 1 | -0.0344585 |
| PERP | PERP, TP53 apoptosis effector | -0.0344238 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0338226 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0334871 |
| CTSD | cathepsin D | -0.0331844 |
| MSI2 | musashi RNA-binding protein 2 | -0.0328457 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.0327806 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.032646 |
| USP34 | ubiquitin specific peptidase 34 | -0.0325507 |
| CCNL1 | cyclin L1 | -0.032468 |
| ZNF207 | zinc finger protein 207 | -0.0322606 |
| DIDO1 | death inducer-obliterator 1 | -0.0318522 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0317935 |
| OGA | O-GlcNAcase | -0.0314167 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0313891 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0311541 |
| ARHGAP12 | Rho GTPase activating protein 12 | -0.0311222 |
| RHEB | Ras homolog enriched in brain | -0.0308057 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0305369 |
| RIGI | RNA sensor RIG-I | -0.0305126 |
| CANX | calnexin | -0.0302565 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0300851 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0298133 |
| CD2AP | CD2-associated protein | -0.0293308 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0290946 |
| ACTG1 | actin gamma 1 | -0.0289731 |
| KCMF1 | potassium channel modulatory factor 1 | -0.0287528 |
| CUX1 | cut-like homeobox 1 | -0.0285004 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0284568 |
| RBMX | RNA binding motif protein, X-linked | -0.0281615 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.0278787 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0278692 |
| NCOR2 | nuclear receptor corepressor 2 | -0.0278161 |
| ATP9A | ATPase, class II, type 9A | -0.0276291 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0272538 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0270581 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0270106 |
| GLG1 | golgi glycoprotein 1 | -0.0268435 |
| VOPP1 | vesicular, overexpressed in cancer, prosurvival protein 1 | -0.0267176 |
| NCOA3 | nuclear receptor coactivator 3 | -0.0264983 |
| PTK2 | protein tyrosine kinase 2 | -0.0264726 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0261875 |
| USP3 | ubiquitin specific peptidase 3 | -0.0255412 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0255366 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0255096 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | -0.0253751 |
| H2AC6 | H2A clustered histone 6 | -0.0251067 |
| UBE3C | ubiquitin protein ligase E3C | -0.0249755 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0249274 |
| MAP4 | microtubule-associated protein 4 | -0.0242607 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0241806 |
| FUS | FUS RNA binding protein | -0.0241759 |
| MX2 | MX dynamin-like GTPase 2 | -0.0239966 |
| TPM3 | tropomyosin 3 | -0.0238755 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0237849 |
| MYH14 | myosin, heavy chain 14, non-muscle | -0.0237281 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0235918 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.0234422 |
