| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | 18β-Glycyrrhetinic acid perturbation in SW48 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the 18β-Glycyrrhetinic acid_SW48 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.125246 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.119693 |
| LMO7 | LIM domain 7 | 0.102959 |
| RCOR1 | REST corepressor 1 | 0.0785094 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0686646 |
| DSPP | dentin sialophosphoprotein | 0.0602327 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0581543 |
| EGFR | epidermal growth factor receptor | 0.0554349 |
| LDHA | lactate dehydrogenase A | 0.052071 |
| PTMA | prothymosin, alpha | 0.0510295 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0484456 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0448413 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0430668 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0409235 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | 0.0408529 |
| ARF1 | ADP-ribosylation factor 1 | 0.0388119 |
| MED13 | mediator complex subunit 13 | 0.0371914 |
| ANXA1 | annexin A1 | 0.0370263 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.036999 |
| NUP50 | nucleoporin 50kDa | 0.0367673 |
| PERP | PERP, TP53 apoptosis effector | 0.0364966 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.0353269 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0350277 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.034638 |
| ANXA2 | annexin A2 | 0.0340962 |
| WDR43 | WD repeat domain 43 | 0.0329731 |
| ATL2 | atlastin GTPase 2 | 0.0329458 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | 0.0316129 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0304252 |
| HMGA1 | high mobility group AT-hook 1 | 0.0304108 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0302501 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | 0.03004 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0299403 |
| SETD5 | SET domain containing 5 | 0.0297918 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0297309 |
| FHL2 | four and a half LIM domains 2 | 0.0296935 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0296363 |
| RPS4X | ribosomal protein S4, X-linked | 0.0292254 |
| RPL7 | ribosomal protein L7 | 0.0286273 |
| HOMER1 | homer scaffolding protein 1 | 0.0286067 |
| CUL5 | cullin 5 | 0.028485 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.028369 |
| UBE3C | ubiquitin protein ligase E3C | 0.0282779 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0282677 |
| LAMA4 | laminin, alpha 4 | 0.0274732 |
| S100A6 | S100 calcium binding protein A6 | 0.0274583 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0273614 |
| TMSB10 | thymosin beta 10 | 0.0272405 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0272048 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0271538 |
| RPLP0 | ribosomal protein, large, P0 | 0.0270452 |
| RACK1 | receptor for activated C kinase 1 | 0.0266178 |
| PARD3 | par-3 family cell polarity regulator | 0.0264927 |
| SNX9 | sorting nexin 9 | 0.0264548 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0263412 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0263028 |
| RPS12 | ribosomal protein S12 | 0.0262571 |
| DSTN | destrin (actin depolymerizing factor) | 0.0261403 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0259377 |
| EMP1 | epithelial membrane protein 1 | 0.0256747 |
| SFTPA2 | surfactant protein A2 | 0.0255198 |
| RPS17 | ribosomal protein S17 | 0.025301 |
| PRPF8 | pre-mRNA processing factor 8 | 0.0251397 |
| YBX1 | Y box binding protein 1 | 0.02505 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0246314 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0246154 |
| RPL18 | ribosomal protein L18 | 0.0245875 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0245757 |
| RPL10A | ribosomal protein L10a | 0.0242812 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0242691 |
| RAB10 | RAB10, member RAS oncogene family | 0.0241425 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0240881 |
| DDX56 | DEAD (Asp-Glu-Ala-Asp) box helicase 56 | 0.0240443 |
| RTN3 | reticulon 3 | 0.0238826 |
| RPS19 | ribosomal protein S19 | 0.0237536 |
| UBAP2 | ubiquitin associated protein 2 | 0.0236769 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0235655 |
| PCBP2 | poly(rC) binding protein 2 | 0.0232874 |
| ACTG1 | actin gamma 1 | 0.023256 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0230554 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.022872 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0227663 |
| BZW2 | basic leucine zipper and W2 domains 2 | 0.0226868 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0223678 |
| OXSR1 | oxidative stress responsive 1 | 0.0223606 |
| EFNB2 | ephrin-B2 | 0.0223481 |
| TMF1 | TATA element modulatory factor 1 | 0.0222469 |
| ZHX2 | zinc fingers and homeoboxes 2 | 0.0221833 |
| POTEF | POTE ankyrin domain family, member F | 0.0221819 |
| MTDH | metadherin | 0.0220633 |
| ECT2 | epithelial cell transforming 2 | 0.0220397 |
| CDK13 | cyclin-dependent kinase 13 | 0.0220004 |
| GSTP1 | glutathione S-transferase pi 1 | 0.0219483 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | 0.021939 |
| NPR2 | natriuretic peptide receptor 2 | 0.0218603 |
| FAM120A | family with sequence similarity 120A | 0.0216767 |
| RPL12 | ribosomal protein L12 | 0.02138 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0213335 |
| GDF15 | growth differentiation factor 15 | 0.0210568 |
| COPA | coatomer protein complex, subunit alpha | 0.0210424 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.150155 |
| FHIT | fragile histidine triad | -0.0988518 |
| AREG | amphiregulin | -0.091973 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0903738 |
| ATXN1 | ataxin 1 | -0.0780182 |
| FLOT1 | flotillin 1 | -0.0731765 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0727579 |
| RNF43 | ring finger protein 43 | -0.0684095 |
| AHNAK | AHNAK nucleoprotein | -0.0600748 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0594688 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0593143 |
| LAMB3 | laminin, beta 3 | -0.0542538 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0540845 |
| RBM25 | RNA binding motif protein 25 | -0.0524753 |
| RAD51B | RAD51 paralog B | -0.0520326 |
| CD36 | CD36 molecule (thrombospondin receptor) | -0.0491644 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0460383 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.043308 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.042045 |
| PFKP | phosphofructokinase, platelet | -0.0420053 |
| RPL37A | ribosomal protein L37a | -0.0417033 |
| OXR1 | oxidation resistance 1 | -0.0407617 |
| AXIN2 | axin 2 | -0.0402918 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0400669 |
| HMGA2 | high mobility group AT-hook 2 | -0.0391435 |
| ITGB4 | integrin, beta 4 | -0.0382812 |
| ITPKC | inositol-trisphosphate 3-kinase C | -0.0376114 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0375568 |
| MTAP | methylthioadenosine phosphorylase | -0.037196 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0370344 |
| CTSB | cathepsin B | -0.0370342 |
| SMYD3 | SET and MYND domain containing 3 | -0.0366475 |
| PHF14 | PHD finger protein 14 | -0.0366432 |
| MT2A | metallothionein 2A | -0.0366213 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0362919 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.0352872 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0349742 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0347104 |
| CAMKMT | calmodulin-lysine N-methyltransferase | -0.0338397 |
| UBC | ubiquitin C | -0.03365 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0330013 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0326222 |
| USP6NL | USP6 N-terminal like | -0.0325467 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0322028 |
| CERS6 | ceramide synthase 6 | -0.0311122 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0307928 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0298438 |
| RPS27A | ribosomal protein S27a | -0.029791 |
| EIF4B | eukaryotic translation initiation factor 4B | -0.0287247 |
| FOSL1 | FOS-like antigen 1 | -0.0286442 |
| HDAC2 | histone deacetylase 2 | -0.0286184 |
| FERMT1 | fermitin family member 1 | -0.0284239 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | -0.0282229 |
| ARFGEF3 | ARFGEF family member 3 | -0.02763 |
| PRELID2 | PRELI domain containing 2 | -0.0276116 |
| ENO1 | enolase 1, (alpha) | -0.027602 |
| SDC4 | syndecan 4 | -0.0272557 |
| LRP8 | low density lipoprotein receptor-related protein 8, apolipoprotein e receptor | -0.0271095 |
| EXOC4 | exocyst complex component 4 | -0.0264246 |
| AVL9 | AVL9 homolog (S. cerevisiase) | -0.0263644 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | -0.0263166 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.0262609 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0256392 |
| MKI67 | marker of proliferation Ki-67 | -0.0253901 |
| MTR | 5-methyltetrahydrofolate-homocysteine methyltransferase | -0.0252985 |
| NIBAN2 | niban apoptosis regulator 2 | -0.0252499 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | -0.0252175 |
| SPIDR | scaffolding protein involved in DNA repair | -0.0249295 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | -0.0246386 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0244774 |
| ANLN | anillin, actin binding protein | -0.0244662 |
| ADGRA3 | adhesion G protein-coupled receptor A3 | -0.02442 |
| AOPEP | aminopeptidase O (putative) | -0.0243192 |
| LUC7L | LUC7-like (S. cerevisiae) | -0.0240866 |
| SGPP2 | sphingosine-1-phosphate phosphatase 2 | -0.0240451 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0235972 |
| ANXA11 | annexin A11 | -0.0233772 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | -0.0232297 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0231788 |
| SMG6 | SMG6 nonsense mediated mRNA decay factor | -0.0230225 |
| GPD2 | glycerol-3-phosphate dehydrogenase 2 (mitochondrial) | -0.0229305 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0227631 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.022716 |
| USP34 | ubiquitin specific peptidase 34 | -0.022558 |
| FLNA | filamin A, alpha | -0.0224908 |
| EREG | epiregulin | -0.0224464 |
| SLC1A5 | solute carrier family 1 (neutral amino acid transporter), member 5 | -0.0223083 |
| ERBIN | erbb2 interacting protein | -0.0222149 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | -0.0221742 |
| FAT1 | FAT atypical cadherin 1 | -0.0221422 |
| KRT8 | keratin 8, type II | -0.0221351 |
| TFDP2 | transcription factor Dp-2 (E2F dimerization partner 2) | -0.0219904 |
| FRAS1 | Fraser extracellular matrix complex subunit 1 | -0.0219842 |
| UMAD1 | UBAP1-MVB12-associated (UMA) domain containing 1 | -0.0219193 |
| VPS41 | vacuolar protein sorting 41 homolog (S. cerevisiae) | -0.0219072 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.021763 |
| PARD6B | par-6 family cell polarity regulator beta | -0.0216182 |
| HMGN3 | high mobility group nucleosomal binding domain 3 | -0.0215136 |
| BCL2L1 | BCL2-like 1 | -0.0214934 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0214687 |
