| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | 18β-Glycyrrhetinic acid perturbation in hTERT-HPNE cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the 18β-Glycyrrhetinic acid_hTERT-HPNE drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| STC1 | stanniocalcin 1 | 0.19414 |
| B2M | beta-2-microglobulin | 0.1314 |
| MT2A | metallothionein 2A | 0.129312 |
| NDRG1 | N-myc downstream regulated 1 | 0.1218 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0992506 |
| TMSB10 | thymosin beta 10 | 0.0980004 |
| HLA-B | major histocompatibility complex, class I, B | 0.0832312 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0810107 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0755336 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0650401 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0620224 |
| HLA-A | major histocompatibility complex, class I, A | 0.0619624 |
| INHBA | inhibin, beta A | 0.0595029 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.057875 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0566284 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0555625 |
| VIM | vimentin | 0.0551058 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0536907 |
| MAP1B | microtubule-associated protein 1B | 0.0491437 |
| RPL37A | ribosomal protein L37a | 0.0483512 |
| RPL12 | ribosomal protein L12 | 0.0480412 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0430086 |
| EGR1 | early growth response 1 | 0.0427182 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0422419 |
| CD44 | CD44 molecule (Indian blood group) | 0.0421632 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0416211 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0413636 |
| FTL | ferritin, light polypeptide | 0.0411305 |
| RPLP0 | ribosomal protein, large, P0 | 0.0406003 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0395339 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.038878 |
| RPS3 | ribosomal protein S3 | 0.0385009 |
| RPS19 | ribosomal protein S19 | 0.035966 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.035822 |
| MYO10 | myosin X | 0.0355367 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0346278 |
| CD59 | CD59 molecule, complement regulatory protein | 0.0346219 |
| RPS8 | ribosomal protein S8 | 0.034586 |
| RPL9 | ribosomal protein L9 | 0.0343525 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.034177 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0339155 |
| CALD1 | caldesmon 1 | 0.0336389 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0335789 |
| RPS12 | ribosomal protein S12 | 0.0333254 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0332108 |
| ATF4 | activating transcription factor 4 | 0.0325347 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0324533 |
| SH3RF1 | SH3 domain containing ring finger 1 | 0.0320859 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | 0.0318735 |
| RPL36 | ribosomal protein L36 | 0.0317594 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0315566 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | 0.0309679 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0306346 |
| LDHA | lactate dehydrogenase A | 0.0305502 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.030464 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.0301151 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0300833 |
| RPL23 | ribosomal protein L23 | 0.0298112 |
| NPTX1 | neuronal pentraxin I | 0.0296776 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0295829 |
| NOTCH2 | notch 2 | 0.0295732 |
| RPL11 | ribosomal protein L11 | 0.0291613 |
| COL8A1 | collagen, type VIII, alpha 1 | 0.0290241 |
| RPL8 | ribosomal protein L8 | 0.0286341 |
| RPS17 | ribosomal protein S17 | 0.0285196 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.0280166 |
| RAB13 | RAB13, member RAS oncogene family | 0.027227 |
| LOX | lysyl oxidase | 0.0272096 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | 0.0269979 |
| RPL28 | ribosomal protein L28 | 0.0268605 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0268501 |
| SIK3 | SIK family kinase 3 | 0.0266196 |
| RPL31 | ribosomal protein L31 | 0.0261493 |
| RPS27 | ribosomal protein S27 | 0.0260123 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.025977 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | 0.0255426 |
| MARCHF3 | membrane associated ring-CH-type finger 3 | 0.0254796 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0254329 |
| KDELR1 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 | 0.0253808 |
| NAV1 | neuron navigator 1 | 0.0249136 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0248066 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0247923 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.024583 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0245522 |
| S100A9 | S100 calcium binding protein A9 | 0.0244035 |
| ARPC1B | actin related protein 2/3 complex, subunit 1B, 41kDa | 0.0241621 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0241555 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0241337 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0239937 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0239589 |
| RPS13 | ribosomal protein S13 | 0.0237458 |
| POTEF | POTE ankyrin domain family, member F | 0.0237003 |
| ANO6 | anoctamin 6 | 0.0235282 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | 0.0233796 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | 0.0233309 |
| GLIS3 | GLIS family zinc finger 3 | 0.0232135 |
| SON | SON DNA binding protein | 0.0230392 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0230231 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.0229876 |
| CPA6 | carboxypeptidase A6 | 0.022832 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.187575 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.140838 |
| COL1A1 | collagen, type I, alpha 1 | -0.138276 |
| MMP1 | matrix metallopeptidase 1 | -0.126286 |
| COL6A3 | collagen, type VI, alpha 3 | -0.125274 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.091282 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0678709 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0668747 |
| SPAG9 | sperm associated antigen 9 | -0.0660941 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | -0.0659646 |
| CANX | calnexin | -0.0643255 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0606644 |
| AHNAK | AHNAK nucleoprotein | -0.0601804 |
| TPM4 | tropomyosin 4 | -0.0544447 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0503814 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0497076 |
| HMGA2 | high mobility group AT-hook 2 | -0.0478353 |
| UBC | ubiquitin C | -0.0437749 |
| CALU | calumenin | -0.0415636 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0413793 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0406958 |
| CALR | calreticulin | -0.0400177 |
| EMP1 | epithelial membrane protein 1 | -0.0398496 |
| FN1 | fibronectin 1 | -0.0391061 |
| APP | amyloid beta (A4) precursor protein | -0.0377695 |
| COL4A2 | collagen, type IV, alpha 2 | -0.035897 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0350679 |
| COL3A1 | collagen, type III, alpha 1 | -0.0346807 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0343759 |
| SBF2 | SET binding factor 2 | -0.0343 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0340692 |
| ADAMTS16 | ADAM metallopeptidase with thrombospondin type 1 motif, 16 | -0.033859 |
| COL5A2 | collagen, type V, alpha 2 | -0.0320553 |
| HLA-E | major histocompatibility complex, class I, E | -0.031587 |
| KIAA1217 | KIAA1217 | -0.0308619 |
| OXR1 | oxidation resistance 1 | -0.0298868 |
| GREM1 | gremlin 1, DAN family BMP antagonist | -0.0295916 |
| COG5 | component of oligomeric golgi complex 5 | -0.0293576 |
| RAI14 | retinoic acid induced 14 | -0.0286186 |
| GPHN | gephyrin | -0.0285666 |
| RRBP1 | ribosome binding protein 1 | -0.0283404 |
| FBN1 | fibrillin 1 | -0.0282994 |
| PDGFRB | platelet-derived growth factor receptor, beta polypeptide | -0.0278643 |
| AUH | AU RNA binding protein/enoyl-CoA hydratase | -0.0276632 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0272791 |
| SUCO | SUN domain containing ossification factor | -0.0272341 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0265531 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0265201 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0261082 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0257816 |
| CAVIN1 | caveolae associated protein 1 | -0.0257721 |
| SNX9 | sorting nexin 9 | -0.0257012 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0256968 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0253858 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0250175 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0243736 |
| USP3 | ubiquitin specific peptidase 3 | -0.0243166 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0241062 |
| TNPO1 | transportin 1 | -0.0239016 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0238482 |
| COPA | coatomer protein complex, subunit alpha | -0.0237658 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | -0.0237189 |
| LAPTM4A | lysosomal protein transmembrane 4 alpha | -0.0236081 |
| COL1A2 | collagen, type I, alpha 2 | -0.0235049 |
| NGLY1 | N-glycanase 1 | -0.0234951 |
| ADAMTS12 | ADAM metallopeptidase with thrombospondin type 1 motif, 12 | -0.0234587 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0232587 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0230505 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0230025 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0228095 |
| CLINT1 | clathrin interactor 1 | -0.0225313 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.0224788 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0224512 |
| MMP12 | matrix metallopeptidase 12 | -0.022221 |
| NUP58 | nucleoporin 58 | -0.0220292 |
| TLN1 | talin 1 | -0.0212281 |
| PRR16 | proline rich 16 | -0.0209721 |
| AFAP1 | actin filament associated protein 1 | -0.0209697 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0209269 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0208914 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0208858 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | -0.0207278 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0206531 |
| ATXN2 | ataxin 2 | -0.0204582 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0204016 |
| MCL1 | myeloid cell leukemia 1 | -0.0201855 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0201749 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0200341 |
| RHOQ | ras homolog family member Q | -0.0199883 |
| NAA16 | N(alpha)-acetyltransferase 16, NatA auxiliary subunit | -0.0199508 |
| DST | dystonin | -0.0199007 |
| PCDH7 | protocadherin 7 | -0.0196581 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | -0.019564 |
| BAALC | brain and acute leukemia, cytoplasmic | -0.0194271 |
| RHOA | ras homolog family member A | -0.0193724 |
| HMGB2 | high mobility group box 2 | -0.0193223 |
| H1-0 | H1.0 linker histone | -0.0188099 |
| PAMR1 | peptidase domain containing associated with muscle regeneration 1 | -0.0187315 |
| ACIN1 | apoptotic chromatin condensation inducer 1 | -0.0186864 |
| HIPK2 | homeodomain interacting protein kinase 2 | -0.0186722 |
