3,4-METHYLENEDIOXYMETHAMPHETAMINE Gene Set

Dataset	DGIdb Drug Targets 2026
Category	physical interactions
Type	drug
Description	A member of the class of benzodioxoles that is 1,3-benzodioxole substituted by a 2-(methylamino)propyl group at position 5. (Chemical Entities of Biological Interest Ontology, CHEBI_1391)
External Link	https://dgidb.org/results?searchType=drug&searchTerms=3,4-METHYLENEDIOXYMETHAMPHETAMINE
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Genes

11 interacting proteins for the 3,4-METHYLENEDIOXYMETHAMPHETAMINE drug from theDGIdb Drug Targets 2026 dataset.

Symbol	Name	Standardized Value
CYP2B6	cytochrome P450, family 2, subfamily B, polypeptide 6	0.209217
SLC18A2	solute carrier family 18 (vesicular monoamine transporter), member 2	0.171857
SLC6A3	solute carrier family 6 (neurotransmitter transporter), member 3	0.121823
SLC6A4	solute carrier family 6 (neurotransmitter transporter), member 4	0.0815593
SLC6A2	solute carrier family 6 (neurotransmitter transporter), member 2	0.0682553
OPRM1	opioid receptor, mu 1	0.0517419
HTR2B	5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled	0.0407797
HTR2C	5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled	0.0331862
HTR2A	5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled	0.0220734
CYP2C19	cytochrome P450, family 2, subfamily C, polypeptide 19	0.0201761
CYP2D6	cytochrome P450, family 2, subfamily D, polypeptide 6	0.0157512