| Dataset | DeepCoverMOA Drug Mechanisms of Action |
| Category | proteomics |
| Type | drug perturbation |
| External Link | https://pubchem.ncbi.nlm.nih.gov/compound/563218 |
| Similar Terms | |
| Downloads & Tools |
199 proteins with high or low expression in 3-Benzotriazol-propionic acid relative to other proteins from the DeepCoverMOA Drug Mechanisms of Action dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PIP | prolactin-induced protein | 0.95 |
| NFE2L3 | nuclear factor, erythroid 2-like 3 | 0.62 |
| RASSF2 | Ras association (RalGDS/AF-6) domain family member 2 | 0.59 |
| SLC3A2 | solute carrier family 3 (amino acid transporter heavy chain), member 2 | 0.53 |
| LRFN1 | leucine rich repeat and fibronectin type III domain containing 1 | 0.48 |
| NDST1 | N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 | 0.46 |
| RAD54L | RAD54-like (S. cerevisiae) | 0.46 |
| FAM76A | family with sequence similarity 76, member A | 0.45 |
| DCLRE1A | DNA cross-link repair 1A | 0.44 |
| ZNF799 | zinc finger protein 799 | 0.44 |
| HSF2 | heat shock transcription factor 2 | 0.44 |
| MRFAP1 | Morf4 family associated protein 1 | 0.42 |
| TSPYL4 | TSPY-like 4 | 0.42 |
| VWA5B2 | von Willebrand factor A domain containing 5B2 | 0.38 |
| PLAUR | plasminogen activator, urokinase receptor | 0.38 |
| NOVA1 | neuro-oncological ventral antigen 1 | 0.37 |
| ARHGEF4 | Rho guanine nucleotide exchange factor (GEF) 4 | 0.37 |
| FAM13A | family with sequence similarity 13, member A | 0.36 |
| DPYSL4 | dihydropyrimidinase-like 4 | 0.36 |
| NHSL1 | NHS-like 1 | 0.36 |
| GOLGA4 | golgin A4 | 0.35 |
| SYTL4 | synaptotagmin-like 4 | 0.35 |
| TYRO3 | TYRO3 protein tyrosine kinase | 0.35 |
| FIZ1 | FLT3-interacting zinc finger 1 | 0.34 |
| NDFIP1 | Nedd4 family interacting protein 1 | 0.34 |
| BMPR1B | bone morphogenetic protein receptor, type IB | 0.34 |
| PUS10 | pseudouridylate synthase 10 | 0.34 |
| ARL4C | ADP-ribosylation factor-like 4C | 0.34 |
| SLC19A2 | solute carrier family 19 (thiamine transporter), member 2 | 0.33 |
| NKAP | NFKB activating protein | 0.33 |
| ALMS1 | Alstrom syndrome protein 1 | 0.33 |
| SEMA6B | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B | 0.32 |
| HSPBAP1 | HSPB (heat shock 27kDa) associated protein 1 | 0.31 |
| TEX15 | testis expressed 15 | 0.31 |
| RAP1GAP2 | RAP1 GTPase activating protein 2 | 0.31 |
| IFFO1 | intermediate filament family orphan 1 | 0.31 |
| LTN1 | listerin E3 ubiquitin protein ligase 1 | 0.3 |
| H1-5 | H1.5 linker histone, cluster member | 0.3 |
| TCHP | trichoplein, keratin filament binding | 0.3 |
| FAM171A1 | family with sequence similarity 171, member A1 | 0.3 |
| MIIP | migration and invasion inhibitory protein | 0.29 |
| PPP2R3A | protein phosphatase 2, regulatory subunit B'', alpha | 0.29 |
| ZNF561 | zinc finger protein 561 | 0.29 |
| SLC25A39 | solute carrier family 25, member 39 | 0.29 |
| PRAME | preferentially expressed antigen in melanoma | 0.29 |
| VWA1 | von Willebrand factor A domain containing 1 | 0.28 |
| R3HDM2 | R3H domain containing 2 | 0.28 |
| RNF145 | ring finger protein 145 | 0.28 |
| PLEKHJ1 | pleckstrin homology domain containing, family J member 1 | 0.28 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | 0.27 |
| SPIRE1 | spire-type actin nucleation factor 1 | 0.27 |
| SOX4 | SRY (sex determining region Y)-box 4 | 0.27 |
| FAU | Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed | 0.27 |
| ENO1 | enolase 1, (alpha) | 0.27 |
| CCDC170 | coiled-coil domain containing 170 | 0.27 |
| FSTL1 | follistatin-like 1 | 0.27 |
| PDE5A | phosphodiesterase 5A, cGMP-specific | 0.27 |
| CCDC112 | coiled-coil domain containing 112 | 0.27 |
| RNASET2 | ribonuclease T2 | 0.26 |
| C12ORF60 | chromosome 12 open reading frame 60 | 0.26 |
| ZNF771 | zinc finger protein 771 | 0.26 |
| SCARA3 | scavenger receptor class A, member 3 | 0.26 |
| WEE1 | WEE1 G2 checkpoint kinase | 0.26 |
| ABAT | 4-aminobutyrate aminotransferase | 0.26 |
| COA5 | cytochrome c oxidase assembly factor 5 | 0.26 |
| FAAP100 | FA core complex associated protein 100 | 0.26 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.26 |
| C6ORF47 | chromosome 6 open reading frame 47 | 0.25 |
| RABIF | RAB interacting factor | 0.25 |
| ZNF511 | zinc finger protein 511 | 0.25 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.25 |
| HMGCR | 3-hydroxy-3-methylglutaryl-CoA reductase | 0.25 |
| ABLIM3 | actin binding LIM protein family, member 3 | 0.25 |
| RAB6B | RAB6B, member RAS oncogene family | 0.24 |
| MINDY4 | MINDY lysine 48 deubiquitinase 4 | 0.24 |
| SVBP | small vasohibin binding protein | 0.24 |
| ANP32E | acidic (leucine-rich) nuclear phosphoprotein 32 family, member E | 0.24 |
| RNF34 | ring finger protein 34, E3 ubiquitin protein ligase | 0.24 |
| KLF10 | Kruppel-like factor 10 | 0.24 |
| AURKAIP1 | aurora kinase A interacting protein 1 | 0.24 |
| DMD | dystrophin | 0.24 |
| RGN | regucalcin | 0.24 |
| MNT | MAX network transcriptional repressor | 0.24 |
| SATB1 | SATB homeobox 1 | 0.23 |
| PIK3C2B | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta | 0.23 |
| CSNK1D | casein kinase 1, delta | 0.23 |
| CPLANE1 | ciliogenesis and planar polarity effector complex subunit 1 | 0.23 |
| ADAT2 | adenosine deaminase, tRNA-specific 2 | 0.23 |
| EEF2KMT | eukaryotic elongation factor 2 lysine methyltransferase | 0.23 |
| TTC30B | tetratricopeptide repeat domain 30B | 0.23 |
| RFXAP | regulatory factor X-associated protein | 0.23 |
| ZNF587B | zinc finger protein 587B | 0.23 |
| MTRF1 | mitochondrial translational release factor 1 | 0.23 |
| KLHL2 | kelch-like family member 2 | 0.23 |
| CCDC97 | coiled-coil domain containing 97 | 0.23 |
| TRAIP | TRAF interacting protein | 0.23 |
| NES | nestin | 0.23 |
| MITD1 | MIT, microtubule interacting and transport, domain containing 1 | 0.23 |
| METTL17 | methyltransferase like 17 | 0.23 |
| BIRC5 | baculoviral IAP repeat containing 5 | 0.22 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ALS2CL | ALS2 C-terminal like | -2.8 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | -0.86 |
| SEPTIN5 | septin 5 | -0.71 |
| ADIRF | adipogenesis regulatory factor | -0.7 |
| VPS37C | vacuolar protein sorting 37 homolog C (S. cerevisiae) | -0.58 |
| PRKCH | protein kinase C, eta | -0.54 |
| TIMM10 | translocase of inner mitochondrial membrane 10 homolog (yeast) | -0.53 |
| GCH1 | GTP cyclohydrolase 1 | -0.5 |
| DNAH1 | dynein, axonemal, heavy chain 1 | -0.48 |
| TRAPPC2 | trafficking protein particle complex 2 | -0.47 |
| PTRHD1 | peptidyl-tRNA hydrolase domain containing 1 | -0.46 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.46 |
| PCBD1 | pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha | -0.45 |
| MYCBP | MYC binding protein | -0.45 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.45 |
| MXRA7 | matrix-remodelling associated 7 | -0.45 |
| TMPO | thymopoietin | -0.44 |
| TPST1 | tyrosylprotein sulfotransferase 1 | -0.44 |
| GDF15 | growth differentiation factor 15 | -0.43 |
| NUCB2 | nucleobindin 2 | -0.43 |
| AMACR | alpha-methylacyl-CoA racemase | -0.43 |
| HBA1 | hemoglobin, alpha 1 | -0.42 |
| KMT2B | lysine (K)-specific methyltransferase 2B | -0.4 |
| MAPK12 | mitogen-activated protein kinase 12 | -0.39 |
| CUTA | cutA divalent cation tolerance homolog (E. coli) | -0.38 |
| BLOC1S1 | biogenesis of lysosomal organelles complex-1, subunit 1 | -0.37 |
| FBXO31 | F-box protein 31 | -0.37 |
| SBSN | suprabasin | -0.36 |
| DES | desmin | -0.36 |
| RPGRIP1L | RPGRIP1-like | -0.35 |
| CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 | -0.34 |
| TNKS2 | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 | -0.34 |
| KBTBD8 | kelch repeat and BTB (POZ) domain containing 8 | -0.34 |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase | -0.34 |
| TMOD2 | tropomodulin 2 (neuronal) | -0.34 |
| MCRIP1 | MAPK regulated corepressor interacting protein 1 | -0.34 |
| S100A6 | S100 calcium binding protein A6 | -0.34 |
| MRPL50 | mitochondrial ribosomal protein L50 | -0.33 |
| JRKL | JRK-like | -0.33 |
| NCBP2AS2 | NCBP2 antisense 2 (head to head) | -0.33 |
| ZNRD2 | zinc ribbon domain containing 2 | -0.33 |
| PCBD2 | pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 2 | -0.33 |
| ATP7A | ATPase, Cu++ transporting, alpha polypeptide | -0.33 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.32 |
| TXN2 | thioredoxin 2 | -0.32 |
| LYSMD2 | LysM, putative peptidoglycan-binding, domain containing 2 | -0.32 |
| NXT2 | nuclear transport factor 2-like export factor 2 | -0.32 |
| EDEM2 | ER degradation enhancer, mannosidase alpha-like 2 | -0.31 |
| NOL3 | nucleolar protein 3 (apoptosis repressor with CARD domain) | -0.31 |
| TMEM173 | transmembrane protein 173 | -0.31 |
| ASNSD1 | asparagine synthetase domain containing 1 | -0.31 |
| S100A14 | S100 calcium binding protein A14 | -0.3 |
| MIF | macrophage migration inhibitory factor (glycosylation-inhibiting factor) | -0.3 |
| GALNT4 | polypeptide N-acetylgalactosaminyltransferase 4 | -0.3 |
| ANAPC11 | anaphase promoting complex subunit 11 | -0.3 |
| TOMM5 | translocase of outer mitochondrial membrane 5 homolog (yeast) | -0.29 |
| PPP1R15B | protein phosphatase 1, regulatory subunit 15B | -0.29 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.29 |
| ATG2A | autophagy related 2A | -0.28 |
| FNIP1 | folliculin interacting protein 1 | -0.28 |
| OGFOD3 | 2-oxoglutarate and iron-dependent oxygenase domain containing 3 | -0.28 |
| VAMP4 | vesicle-associated membrane protein 4 | -0.28 |
| PCMTD2 | protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2 | -0.27 |
| CENPH | centromere protein H | -0.27 |
| SRI | sorcin | -0.27 |
| TPM2 | tropomyosin 2 (beta) | -0.27 |
| ZNF276 | zinc finger protein 276 | -0.27 |
| KDELR1 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 | -0.27 |
| KDELR3 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 | -0.27 |
| PFDN1 | prefoldin subunit 1 | -0.27 |
| GID8 | GID complex subunit 8 | -0.27 |
| ZNF776 | zinc finger protein 776 | -0.27 |
| TPM1 | tropomyosin 1 (alpha) | -0.27 |
| CCN2 | cellular communication network factor 2 | -0.26 |
| APOE | apolipoprotein E | -0.26 |
| SH2B2 | SH2B adaptor protein 2 | -0.26 |
| TOM1L2 | target of myb1-like 2 (chicken) | -0.26 |
| SOCS2 | suppressor of cytokine signaling 2 | -0.26 |
| RCAN1 | regulator of calcineurin 1 | -0.26 |
| HGH1 | HGH1 homolog (S. cerevisiae) | -0.26 |
| ATP9A | ATPase, class II, type 9A | -0.26 |
| HRH1 | histamine receptor H1 | -0.26 |
| MGMT | O-6-methylguanine-DNA methyltransferase | -0.26 |
| HYKK | hydroxylysine kinase | -0.26 |
| UBE2F | ubiquitin-conjugating enzyme E2F (putative) | -0.26 |
| TMSB10 | thymosin beta 10 | -0.25 |
| FEM1C | fem-1 homolog c (C. elegans) | -0.25 |
| PUDP | pseudouridine 5'-phosphatase | -0.25 |
| TPM4 | tropomyosin 4 | -0.25 |
| PGPEP1 | pyroglutamyl-peptidase I | -0.25 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.25 |
| SS18 | synovial sarcoma translocation, chromosome 18 | -0.25 |
| ZNF646 | zinc finger protein 646 | -0.25 |
| FLNB | filamin B, beta | -0.25 |
| S100A11 | S100 calcium binding protein A11 | -0.25 |
| CSTF2 | cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa | -0.25 |
| NENF | neudesin neurotrophic factor | -0.25 |
| TM7SF2 | transmembrane 7 superfamily member 2 | -0.25 |
| SUCLG2 | succinate-CoA ligase, GDP-forming, beta subunit | -0.25 |
