3-acetamidocoumarin-7361 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the 3-acetamidocoumarin-7361 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
ALS2CL ALS2 C-terminal like
AP4E1 adaptor-related protein complex 4, epsilon 1 subunit
ARHGEF9 Cdc42 guanine nucleotide exchange factor (GEF) 9
ARTN artemin
ATAD5 ATPase family, AAA domain containing 5
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
ATXN2L ataxin 2-like
BRF1 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CACNG1 calcium channel, voltage-dependent, gamma subunit 1
CACYBP calcyclin binding protein
CAMK1 calcium/calmodulin-dependent protein kinase I
CARD9 caspase recruitment domain family, member 9
CCDC71 coiled-coil domain containing 71
CD8A CD8a molecule
CDKN2A cyclin-dependent kinase inhibitor 2A
CNTFR ciliary neurotrophic factor receptor
CSF1R colony stimulating factor 1 receptor
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DAGLA diacylglycerol lipase, alpha
DIEXF digestive organ expansion factor homolog (zebrafish)
DIO2 deiodinase, iodothyronine, type II
DNAJC4 DnaJ (Hsp40) homolog, subfamily C, member 4
DSCAM Down syndrome cell adhesion molecule
DUSP2 dual specificity phosphatase 2
E2F4 E2F transcription factor 4, p107/p130-binding
EDEM3 ER degradation enhancer, mannosidase alpha-like 3
EPHB2 EPH receptor B2
FAM214B family with sequence similarity 214, member B
FAM46C family with sequence similarity 46, member C
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GNG3 guanine nucleotide binding protein (G protein), gamma 3
GON4L gon-4-like (C. elegans)
GOSR2 golgi SNAP receptor complex member 2
GPRIN2 G protein regulated inducer of neurite outgrowth 2
HAAO 3-hydroxyanthranilate 3,4-dioxygenase
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4
HFE hemochromatosis
HOMER3 homer scaffolding protein 3
HOXD1 homeobox D1
HPS4 Hermansky-Pudlak syndrome 4
IFT27 intraflagellar transport 27
IQCK IQ motif containing K
IRS2 insulin receptor substrate 2
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
LMNA lamin A/C
LONP2 lon peptidase 2, peroxisomal
LPPR2 lipid phosphate phosphatase-related protein type 2
LRRC14 leucine rich repeat containing 14
LRRC20 leucine rich repeat containing 20
LRRC23 leucine rich repeat containing 23
MAP3K6 mitogen-activated protein kinase kinase kinase 6
MARK4 MAP/microtubule affinity-regulating kinase 4
MMRN2 multimerin 2
N4BP3 NEDD4 binding protein 3
NDRG2 NDRG family member 2
NOS1 nitric oxide synthase 1 (neuronal)
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PAX5 paired box 5
PAX6 paired box 6
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PLIN2 perilipin 2
PPP4R4 protein phosphatase 4, regulatory subunit 4
PRF1 perforin 1 (pore forming protein)
PRUNE2 prune homolog 2 (Drosophila)
PSG9 pregnancy specific beta-1-glycoprotein 9
PTK6 protein tyrosine kinase 6
RALGPS1 Ral GEF with PH domain and SH3 binding motif 1
RASAL2 RAS protein activator like 2
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RERE arginine-glutamic acid dipeptide (RE) repeats
RPS14 ribosomal protein S14
RSU1 Ras suppressor protein 1
SAA3P serum amyloid A3 pseudogene
SAMD9 sterile alpha motif domain containing 9
SBF1 SET binding factor 1
SCGB2A2 secretoglobin, family 2A, member 2
SECTM1 secreted and transmembrane 1
SH2D3A SH2 domain containing 3A
SH3BP2 SH3-domain binding protein 2
SIPA1L1 signal-induced proliferation-associated 1 like 1
SOX3 SRY (sex determining region Y)-box 3
TEX40 testis expressed 40
TOP3A topoisomerase (DNA) III alpha
TRIB2 tribbles pseudokinase 2
TRIM3 tripartite motif containing 3
UPK2 uroplakin 2
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VPS13D vacuolar protein sorting 13 homolog D (S. cerevisiae)
YIF1B Yip1 interacting factor homolog B (S. cerevisiae)
ZCCHC14 zinc finger, CCHC domain containing 14
ZNF329 zinc finger protein 329
ZNF778 zinc finger protein 778

decreased expression

Symbol Name
ACTL8 actin-like 8
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
ADCY7 adenylate cyclase 7
ANKZF1 ankyrin repeat and zinc finger domain containing 1
APH1B APH1B gamma secretase subunit
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ARL15 ADP-ribosylation factor-like 15
ARMC6 armadillo repeat containing 6
BCAS1 breast carcinoma amplified sequence 1
C22ORF29 chromosome 22 open reading frame 29
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2
CD82 CD82 molecule
CDON cell adhesion associated, oncogene regulated
CEP97 centrosomal protein 97kDa
CHML choroideremia-like (Rab escort protein 2)
CHST12 carbohydrate (chondroitin 4) sulfotransferase 12
CLCN5 chloride channel, voltage-sensitive 5
CTC1 CTS telomere maintenance complex component 1
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DCAF4 DDB1 and CUL4 associated factor 4
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
ELP3 elongator acetyltransferase complex subunit 3
EMID1 EMI domain containing 1
ERN2 endoplasmic reticulum to nucleus signaling 2
FAM186A family with sequence similarity 186, member A
FBXL2 F-box and leucine-rich repeat protein 2
FOXN2 forkhead box N2
GBP2 guanylate binding protein 2, interferon-inducible
GDAP1 ganglioside induced differentiation associated protein 1
GPATCH2L G patch domain containing 2-like
GPC3 glypican 3
GRB7 growth factor receptor-bound protein 7
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
HIST1H1D histone cluster 1, H1d
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
HYI hydroxypyruvate isomerase (putative)
IFI6 interferon, alpha-inducible protein 6
IFITM1 interferon induced transmembrane protein 1
ITPKB inositol-trisphosphate 3-kinase B
KCNF1 potassium channel, voltage gated modifier subfamily F, member 1
KIAA0754 KIAA0754
KRT24 keratin 24, type I
LAMB3 laminin, beta 3
LARP6 La ribonucleoprotein domain family, member 6
MANBA mannosidase, beta A, lysosomal
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MTA2 metastasis associated 1 family, member 2
MVD mevalonate (diphospho) decarboxylase
NEK11 NIMA-related kinase 11
NKAIN1 Na+/K+ transporting ATPase interacting 1
NT5C 5', 3'-nucleotidase, cytosolic
NUS1P3 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) pseudogene 3
PCDHA6 protocadherin alpha 6
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1
PLEKHA6 pleckstrin homology domain containing, family A member 6
POM121 POM121 transmembrane nucleoporin
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
RNF123 ring finger protein 123
RNF25 ring finger protein 25
SH2D4A SH2 domain containing 4A
SIDT1 SID1 transmembrane family, member 1
SIM2 single-minded family bHLH transcription factor 2
SIRT2 sirtuin 2
SLC37A1 solute carrier family 37 (glucose-6-phosphate transporter), member 1
SLC46A3 solute carrier family 46, member 3
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
SOX12 SRY (sex determining region Y)-box 12
SP1 Sp1 transcription factor
SPINK1 serine peptidase inhibitor, Kazal type 1
SREK1IP1 SREK1-interacting protein 1
STARD3 StAR-related lipid transfer (START) domain containing 3
SYNC syncoilin, intermediate filament protein
TBX19 T-box 19
TESC tescalcin
TESPA1 thymocyte expressed, positive selection associated 1
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TICAM1 toll-like receptor adaptor molecule 1
TMEM2 transmembrane protein 2
TMEM51 transmembrane protein 51
TMSB15A thymosin beta 15a
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator
TNS2 tensin 2
TPCN1 two pore segment channel 1
TPST2 tyrosylprotein sulfotransferase 2
TRAIP TRAF interacting protein
TSPAN1 tetraspanin 1
TUBG2 tubulin, gamma 2
VAX2 ventral anterior homeobox 2
WDR62 WD repeat domain 62
ZFP30 ZFP30 zinc finger protein
ZNF134 zinc finger protein 134
ZNF211 zinc finger protein 211
ZNF606 zinc finger protein 606
ZNF747 zinc finger protein 747
ZNF862 zinc finger protein 862
ZNHIT2 zinc finger, HIT-type containing 2