3-aminobenzamide-590 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the 3-aminobenzamide-590 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACAN aggrecan
ADARB1 adenosine deaminase, RNA-specific, B1
ADD2 adducin 2 (beta)
AMBRA1 autophagy/beclin-1 regulator 1
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5
ATP13A2 ATPase type 13A2
BCR breakpoint cluster region
C16ORF58 chromosome 16 open reading frame 58
C9ORF156 chromosome 9 open reading frame 156
CAV1 caveolin 1, caveolae protein, 22kDa
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2
CC2D1A coiled-coil and C2 domain containing 1A
CENPT centromere protein T
COL18A1 collagen, type XVIII, alpha 1
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DEFA5 defensin, alpha 5, Paneth cell-specific
DERL1 derlin 1
DLX2 distal-less homeobox 2
EGR3 early growth response 3
EML2 echinoderm microtubule associated protein like 2
EPAS1 endothelial PAS domain protein 1
EPN1 epsin 1
ESR1 estrogen receptor 1
FASTK Fas-activated serine/threonine kinase
FGFR1 fibroblast growth factor receptor 1
FGFR3 fibroblast growth factor receptor 3
FOXC1 forkhead box C1
FOXRED2 FAD-dependent oxidoreductase domain containing 2
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
FXR2 fragile X mental retardation, autosomal homolog 2
GADD45B growth arrest and DNA-damage-inducible, beta
GALK1 galactokinase 1
GPR107 G protein-coupled receptor 107
HIF1AN hypoxia inducible factor 1, alpha subunit inhibitor
HIST1H4J histone cluster 1, H4j
HOXC10 homeobox C10
IDO1 indoleamine 2,3-dioxygenase 1
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
IL1RN interleukin 1 receptor antagonist
IQSEC1 IQ motif and Sec7 domain 1
IRF7 interferon regulatory factor 7
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1
KDELR3 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
KIAA0141 KIAA0141
KLF4 Kruppel-like factor 4 (gut)
LANCL1 LanC lantibiotic synthetase component C-like 1 (bacterial)
LIAS lipoic acid synthetase
LPP LIM domain containing preferred translocation partner in lipoma
LRRN3 leucine rich repeat neuronal 3
MAPK3 mitogen-activated protein kinase 3
MEF2A myocyte enhancer factor 2A
MT1H metallothionein 1H
MT1HL1 metallothionein 1H-like 1
MUL1 mitochondrial E3 ubiquitin protein ligase 1
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
NAAA N-acylethanolamine acid amidase
NCAPH2 non-SMC condensin II complex, subunit H2
NCOA1 nuclear receptor coactivator 1
NPPA natriuretic peptide A
NPR2 natriuretic peptide receptor 2
NPRL2 nitrogen permease regulator-like 2 (S. cerevisiae)
NR2F6 nuclear receptor subfamily 2, group F, member 6
NR4A1 nuclear receptor subfamily 4, group A, member 1
OCRL oculocerebrorenal syndrome of Lowe
OXLD1 oxidoreductase-like domain containing 1
PAQR6 progestin and adipoQ receptor family member VI
PBX1 pre-B-cell leukemia homeobox 1
PIGV phosphatidylinositol glycan anchor biosynthesis, class V
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1
PLEKHG6 pleckstrin homology domain containing, family G (with RhoGef domain) member 6
PLSCR3 phospholipid scramblase 3
PRB1 proline-rich protein BstNI subfamily 1
PRPH peripherin
RAD54L RAD54-like (S. cerevisiae)
RBM14 RNA binding motif protein 14
RGS17 regulator of G-protein signaling 17
RNF208 ring finger protein 208
RRP1B ribosomal RNA processing 1B
RUNX1 runt-related transcription factor 1
RXRB retinoid X receptor, beta
SHMT1 serine hydroxymethyltransferase 1 (soluble)
SIDT2 SID1 transmembrane family, member 2
SIGMAR1 sigma non-opioid intracellular receptor 1
SLC17A4 solute carrier family 17, member 4
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SZRD1 SUZ RNA binding domain containing 1
TAOK2 TAO kinase 2
TGFBRAP1 transforming growth factor, beta receptor associated protein 1
TMEM135 transmembrane protein 135
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TPRA1 transmembrane protein, adipocyte asscociated 1
TRADD TNFRSF1A-associated via death domain
TRD T cell receptor delta locus
TSLIG2 tRNA splicing ligase complex subunit 2
UMPS uridine monophosphate synthetase
UQCC1 ubiquinol-cytochrome c reductase complex assembly factor 1
ZNF266 zinc finger protein 266
ZNF783 zinc finger family member 783
ZNF821 zinc finger protein 821

decreased expression

Symbol Name
ACSF2 acyl-CoA synthetase family member 2
ACVR2B activin A receptor, type IIB
ADAMTS9 ADAM metallopeptidase with thrombospondin type 1 motif, 9
ADAMTSL4 ADAMTS-like 4
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
APH1A APH1A gamma secretase subunit
ARID3A AT rich interactive domain 3A (BRIGHT-like)
BCORL1 BCL6 corepressor-like 1
CA9 carbonic anhydrase IX
CARTPT CART prepropeptide
CD82 CD82 molecule
CIC capicua transcriptional repressor
CLEC4E C-type lectin domain family 4, member E
CSN2 casein beta
CWC25 CWC25 spliceosome-associated protein homolog (S. cerevisiae)
DECR2 2,4-dienoyl CoA reductase 2, peroxisomal
DONSON downstream neighbor of SON
DPEP1 dipeptidase 1 (renal)
DRP2 dystrophin related protein 2
DUSP22 dual specificity phosphatase 22
DUSP5 dual specificity phosphatase 5
ECT2 epithelial cell transforming 2
ENTPD3 ectonucleoside triphosphate diphosphohydrolase 3
EPHA2 EPH receptor A2
FAM171A1 family with sequence similarity 171, member A1
FAM189B family with sequence similarity 189, member B
FBXL6 F-box and leucine-rich repeat protein 6
FGFBP1 fibroblast growth factor binding protein 1
FOXD1 forkhead box D1
FZD2 frizzled class receptor 2
GGNBP2 gametogenetin binding protein 2
GMPPB GDP-mannose pyrophosphorylase B
GP6 glycoprotein VI (platelet)
GPRC5D G protein-coupled receptor, class C, group 5, member D
GPX2 glutathione peroxidase 2
GRPR gastrin-releasing peptide receptor
GUSBP3 glucuronidase, beta pseudogene 3
H2AFY2 H2A histone family, member Y2
HOXC5 homeobox C5
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
INTS9 integrator complex subunit 9
IP6K1 inositol hexakisphosphate kinase 1
IRF2 interferon regulatory factor 2
ITPKB inositol-trisphosphate 3-kinase B
JOSD1 Josephin domain containing 1
LMBR1L limb development membrane protein 1-like
LOC642236 FSHD region gene 1 pseudogene
LRRC15 leucine rich repeat containing 15
LUZP4 leucine zipper protein 4
MAGOHB mago-nashi homolog B (Drosophila)
MEIS3P1 Meis homeobox 3 pseudogene 1
METTL8 methyltransferase like 8
MICU2 mitochondrial calcium uptake 2
MIS18A MIS18 kinetochore protein A
MON1B MON1 secretory trafficking family member B
MT3 metallothionein 3
NOTCH1 notch 1
NR1H2 nuclear receptor subfamily 1, group H, member 2
NTNG1 netrin G1
OR1D2 olfactory receptor, family 1, subfamily D, member 2
PHLDA2 pleckstrin homology-like domain, family A, member 2
PRODH2 proline dehydrogenase (oxidase) 2
PRPF38B pre-mRNA processing factor 38B
PRPH2 peripherin 2 (retinal degeneration, slow)
PTPRE protein tyrosine phosphatase, receptor type, E
PTPRT protein tyrosine phosphatase, receptor type, T
PUS7L pseudouridylate synthase 7 homolog (S. cerevisiae)-like
PXN paxillin
RAB4B RAB4B, member RAS oncogene family
RAMP3 receptor (G protein-coupled) activity modifying protein 3
RASAL1 RAS protein activator like 1 (GAP1 like)
RFPL3 ret finger protein-like 3
SCPEP1 serine carboxypeptidase 1
SELL selectin L
SIRT1 sirtuin 1
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC39A7 solute carrier family 39 (zinc transporter), member 7
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
SLC7A9 solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9
SLMO2 slowmo homolog 2 (Drosophila)
SP1 Sp1 transcription factor
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
TARBP1 TAR (HIV-1) RNA binding protein 1
TEX40 testis expressed 40
THRB thyroid hormone receptor, beta
TJP2 tight junction protein 2
TMEM206 transmembrane protein 206
TMEM223 transmembrane protein 223
TMPRSS5 transmembrane protease, serine 5
TP53BP1 tumor protein p53 binding protein 1
TP53I3 tumor protein p53 inducible protein 3
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1
UGGT1 UDP-glucose glycoprotein glucosyltransferase 1
VAV1 vav 1 guanine nucleotide exchange factor
VIPR1 vasoactive intestinal peptide receptor 1
WASF2 WAS protein family, member 2
WDR5B WD repeat domain 5B
ZBED1 zinc finger, BED-type containing 1
ZNF143 zinc finger protein 143