| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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200 genes differentially expressed following the 3-hydroxy-DL-kynurenine-1109 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 |
| APH1B | APH1B gamma secretase subunit |
| APP | amyloid beta (A4) precursor protein |
| ARAP2 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 |
| ARHGAP35 | Rho GTPase activating protein 35 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 |
| ARIH2 | ariadne RBR E3 ubiquitin protein ligase 2 |
| ARL4C | ADP-ribosylation factor-like 4C |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 |
| BEX4 | brain expressed, X-linked 4 |
| C9ORF91 | chromosome 9 open reading frame 91 |
| CAMKK2 | calcium/calmodulin-dependent protein kinase kinase 2, beta |
| CCDC91 | coiled-coil domain containing 91 |
| CEP68 | centrosomal protein 68kDa |
| CLCN3 | chloride channel, voltage-sensitive 3 |
| CROT | carnitine O-octanoyltransferase |
| CSGALNACT2 | chondroitin sulfate N-acetylgalactosaminyltransferase 2 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 |
| DNAJC16 | DnaJ (Hsp40) homolog, subfamily C, member 16 |
| DNMBP | dynamin binding protein |
| ENDOD1 | endonuclease domain containing 1 |
| ERMAP | erythroblast membrane-associated protein (Scianna blood group) |
| ERO1L | ERO1-like (S. cerevisiae) |
| EYA2 | EYA transcriptional coactivator and phosphatase 2 |
| FAM114A2 | family with sequence similarity 114, member A2 |
| FAM188A | family with sequence similarity 188, member A |
| FAN1 | FANCD2/FANCI-associated nuclease 1 |
| FARP1 | FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) |
| FAS | Fas cell surface death receptor |
| FBXL18 | F-box and leucine-rich repeat protein 18 |
| FLJ42627 | uncharacterized LOC645644 |
| FOXRED2 | FAD-dependent oxidoreductase domain containing 2 |
| GALNT11 | polypeptide N-acetylgalactosaminyltransferase 11 |
| GFOD1 | glucose-fructose oxidoreductase domain containing 1 |
| GNG10 | guanine nucleotide binding protein (G protein), gamma 10 |
| HECTD4 | HECT domain containing E3 ubiquitin protein ligase 4 |
| HGH1 | HGH1 homolog (S. cerevisiae) |
| HLA-F | major histocompatibility complex, class I, F |
| HN1L | hematological and neurological expressed 1-like |
| JRK | Jrk homolog (mouse) |
| KLF6 | Kruppel-like factor 6 |
| LAMB2 | laminin, beta 2 (laminin S) |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 |
| MOSPD2 | motile sperm domain containing 2 |
| MPDZ | multiple PDZ domain protein |
| MPP6 | membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6) |
| MTA1 | metastasis associated 1 |
| NABP2 | nucleic acid binding protein 2 |
| NCKAP1 | NCK-associated protein 1 |
| NEK1 | NIMA-related kinase 1 |
| NSUN5P2 | NOP2/Sun domain family, member 5 pseudogene 2 |
| PADI2 | peptidyl arginine deiminase, type II |
| PCOLCE2 | procollagen C-endopeptidase enhancer 2 |
| PDCL | phosducin-like |
| PHF8 | PHD finger protein 8 |
| PHIP | pleckstrin homology domain interacting protein |
| PLEK2 | pleckstrin 2 |
| PPAP2C | phosphatidic acid phosphatase type 2C |
| PRKACB | protein kinase, cAMP-dependent, catalytic, beta |
| PSEN2 | presenilin 2 |
| PUS7L | pseudouridylate synthase 7 homolog (S. cerevisiae)-like |
| PVT1 | Pvt1 oncogene (non-protein coding) |
| PXN | paxillin |
| RAB29 | RAB29, member RAS oncogene family |
| RAI14 | retinoic acid induced 14 |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 |
| RCN2 | reticulocalbin 2, EF-hand calcium binding domain |
| RECQL4 | RecQ protein-like 4 |
| RHOT1 | ras homolog family member T1 |
| RIPK1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 |
| RNFT1 | ring finger protein, transmembrane 1 |
| RPL13P5 | ribosomal protein L13 pseudogene 5 |
| SCAMP1 | secretory carrier membrane protein 1 |
| SECISBP2L | SECIS binding protein 2-like |
| SENP5 | SUMO1/sentrin specific peptidase 5 |
| SHPK | sedoheptulokinase |
| SIK3 | SIK family kinase 3 |
| SIKE1 | suppressor of IKBKE 1 |
| SIN3B | SIN3 transcription regulator family member B |
| SLC25A17 | solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein, 34kDa), member 17 |
| SLC37A1 | solute carrier family 37 (glucose-6-phosphate transporter), member 1 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SMARCC2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 |
| SRSF8 | serine/arginine-rich splicing factor 8 |
| SSBP2 | single-stranded DNA binding protein 2 |
| STAT5B | signal transducer and activator of transcription 5B |
| STX2 | syntaxin 2 |
| SULF1 | sulfatase 1 |
| SYNJ2 | synaptojanin 2 |
| TCAF1 | TRPM8 channel-associated factor 1 |
| TRAF5 | TNF receptor-associated factor 5 |
| TWF1 | twinfilin actin binding protein 1 |
| UBAP1 | ubiquitin associated protein 1 |
| UBTF | upstream binding transcription factor, RNA polymerase I |
| UHRF1BP1L | UHRF1 binding protein 1-like |
| URGCP | upregulator of cell proliferation |
| WIPF2 | WAS/WASL interacting protein family, member 2 |
| XRCC4 | X-ray repair complementing defective repair in Chinese hamster cells 4 |
| ZSCAN32 | zinc finger and SCAN domain containing 32 |
| Symbol | Name |
|---|---|
| ACAD8 | acyl-CoA dehydrogenase family, member 8 |
| ACIN1 | apoptotic chromatin condensation inducer 1 |
| ADAM15 | ADAM metallopeptidase domain 15 |
| AHR | aryl hydrocarbon receptor |
| ANKHD1 | ankyrin repeat and KH domain containing 1 |
| APPL1 | adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 |
| ARHGAP17 | Rho GTPase activating protein 17 |
| ARMC7 | armadillo repeat containing 7 |
| ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 |
| C4ORF19 | chromosome 4 open reading frame 19 |
| CCDC28A | coiled-coil domain containing 28A |
| CDIPT | CDP-diacylglycerol--inositol 3-phosphatidyltransferase |
| CDKN2AIP | CDKN2A interacting protein |
| CENPJ | centromere protein J |
| CHAF1B | chromatin assembly factor 1, subunit B (p60) |
| CLDN7 | claudin 7 |
| COG4 | component of oligomeric golgi complex 4 |
| COQ4 | coenzyme Q4 |
| CPTP | ceramide-1-phosphate transfer protein |
| CST3 | cystatin C |
| CTNNBL1 | catenin, beta like 1 |
| DBNDD1 | dysbindin (dystrobrevin binding protein 1) domain containing 1 |
| DDX54 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 |
| DGKZ | diacylglycerol kinase, zeta |
| DIP2A | DIP2 disco-interacting protein 2 homolog A (Drosophila) |
| ECHDC1 | ethylmalonyl-CoA decarboxylase 1 |
| ECHDC3 | enoyl CoA hydratase domain containing 3 |
| EDC4 | enhancer of mRNA decapping 4 |
| EGR3 | early growth response 3 |
| EMC7 | ER membrane protein complex subunit 7 |
| FAH | fumarylacetoacetate hydrolase (fumarylacetoacetase) |
| FJX1 | four jointed box 1 (Drosophila) |
| FSD1 | fibronectin type III and SPRY domain containing 1 |
| FXN | frataxin |
| GMPPA | GDP-mannose pyrophosphorylase A |
| GNB2 | guanine nucleotide binding protein (G protein), beta polypeptide 2 |
| GTF2F2 | general transcription factor IIF, polypeptide 2, 30kDa |
| HOOK1 | hook microtubule-tethering protein 1 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa |
| IL10RB | interleukin 10 receptor, beta |
| INPP5A | inositol polyphosphate-5-phosphatase, 40kDa |
| KCTD15 | potassium channel tetramerization domain containing 15 |
| KCTD9 | potassium channel tetramerization domain containing 9 |
| KIAA0232 | KIAA0232 |
| KLHL12 | kelch-like family member 12 |
| KRT86 | keratin 86, type II |
| LGMN | legumain |
| LIAS | lipoic acid synthetase |
| LRRC16A | leucine rich repeat containing 16A |
| MAPKAPK5 | mitogen-activated protein kinase-activated protein kinase 5 |
| MIS12 | MIS12 kinetochore complex component |
| MMACHC | methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria |
| MNS1 | meiosis-specific nuclear structural 1 |
| MNX1 | motor neuron and pancreas homeobox 1 |
| MPST | mercaptopyruvate sulfurtransferase |
| MSL2 | male-specific lethal 2 homolog (Drosophila) |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog |
| MYH9 | myosin, heavy chain 9, non-muscle |
| NCS1 | neuronal calcium sensor 1 |
| NMB | neuromedin B |
| NMU | neuromedin U |
| PEPD | peptidase D |
| PES1 | pescadillo ribosomal biogenesis factor 1 |
| PHLDA3 | pleckstrin homology-like domain, family A, member 3 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 |
| PNKP | polynucleotide kinase 3'-phosphatase |
| PP14571 | uncharacterized LOC100130449 |
| PRSS23 | protease, serine, 23 |
| PSMB10 | proteasome (prosome, macropain) subunit, beta type, 10 |
| PYGB | phosphorylase, glycogen; brain |
| QTRT1 | queuine tRNA-ribosyltransferase 1 |
| RASSF1 | Ras association (RalGDS/AF-6) domain family member 1 |
| REEP4 | receptor accessory protein 4 |
| RGS19 | regulator of G-protein signaling 19 |
| RPS6KA1 | ribosomal protein S6 kinase, 90kDa, polypeptide 1 |
| RSAD1 | radical S-adenosyl methionine domain containing 1 |
| SAMHD1 | SAM domain and HD domain 1 |
| SH2B2 | SH2B adaptor protein 2 |
| SHROOM2 | shroom family member 2 |
| SLC25A40 | solute carrier family 25, member 40 |
| SLC35A5 | solute carrier family 35, member A5 |
| SLC38A10 | solute carrier family 38, member 10 |
| SLC39A1 | solute carrier family 39 (zinc transporter), member 1 |
| SMU1 | smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans) |
| SPATA2L | spermatogenesis associated 2-like |
| STEAP3 | STEAP family member 3, metalloreductase |
| STRN4 | striatin, calmodulin binding protein 4 |
| TBP | TATA box binding protein |
| TEX264 | testis expressed 264 |
| TGFBI | transforming growth factor, beta-induced, 68kDa |
| THAP11 | THAP domain containing 11 |
| THUMPD2 | THUMP domain containing 2 |
| TIMM10B | translocase of inner mitochondrial membrane 10 homolog B (yeast) |
| TMEM127 | transmembrane protein 127 |
| TP53I3 | tumor protein p53 inducible protein 3 |
| VPS11 | vacuolar protein sorting 11 homolog (S. cerevisiae) |
| ZDHHC24 | zinc finger, DHHC-type containing 24 |
| ZNF33B | zinc finger protein 33B |
| ZNF84 | zinc finger protein 84 |
| ZNF85 | zinc finger protein 85 |
