| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the 3-hydroxy-DL-kynurenine-1300 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCB4 | ATP-binding cassette, sub-family B (MDR/TAP), member 4 |
| AKAP13 | A kinase (PRKA) anchor protein 13 |
| ANKRD12 | ankyrin repeat domain 12 |
| APP | amyloid beta (A4) precursor protein |
| ARFGAP1 | ADP-ribosylation factor GTPase activating protein 1 |
| BAX | BCL2-associated X protein |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide |
| BLVRA | biliverdin reductase A |
| BMP1 | bone morphogenetic protein 1 |
| BMP2K | BMP2 inducible kinase |
| BTBD18 | BTB (POZ) domain containing 18 |
| CARD14 | caspase recruitment domain family, member 14 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase |
| CCND1 | cyclin D1 |
| CDK10 | cyclin-dependent kinase 10 |
| CDS1 | CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1 |
| CELSR1 | cadherin, EGF LAG seven-pass G-type receptor 1 |
| CHN2 | chimerin 2 |
| COMT | catechol-O-methyltransferase |
| COX4I1 | cytochrome c oxidase subunit IV isoform 1 |
| CSF2RA | colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) |
| CYB561 | cytochrome b561 |
| CYP3A4 | cytochrome P450, family 3, subfamily A, polypeptide 4 |
| DDX6 | DEAD (Asp-Glu-Ala-Asp) box helicase 6 |
| DHRS12 | dehydrogenase/reductase (SDR family) member 12 |
| DIAPH1 | diaphanous-related formin 1 |
| EIF2AK1 | eukaryotic translation initiation factor 2-alpha kinase 1 |
| EML3 | echinoderm microtubule associated protein like 3 |
| ESRRA | estrogen-related receptor alpha |
| EXPH5 | exophilin 5 |
| FLRT2 | fibronectin leucine rich transmembrane protein 2 |
| FST | follistatin |
| FZD7 | frizzled class receptor 7 |
| GDPD3 | glycerophosphodiester phosphodiesterase domain containing 3 |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HCN4 | hyperpolarization activated cyclic nucleotide gated potassium channel 4 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 |
| HIST1H2AJ | histone cluster 1, H2aj |
| HOXA1 | homeobox A1 |
| IFI30 | interferon, gamma-inducible protein 30 |
| INF2 | inverted formin, FH2 and WH2 domain containing |
| IQSEC1 | IQ motif and Sec7 domain 1 |
| ITM2B | integral membrane protein 2B |
| KANK1 | KN motif and ankyrin repeat domains 1 |
| KAT6A | K(lysine) acetyltransferase 6A |
| LPCAT4 | lysophosphatidylcholine acyltransferase 4 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 |
| LSM4 | LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase |
| MED16 | mediator complex subunit 16 |
| MRPL4 | mitochondrial ribosomal protein L4 |
| MTRF1L | mitochondrial translational release factor 1-like |
| NFYA | nuclear transcription factor Y, alpha |
| OR7E156P | olfactory receptor, family 7, subfamily E, member 156 pseudogene |
| PDSS2 | prenyl (decaprenyl) diphosphate synthase, subunit 2 |
| PDZD7 | PDZ domain containing 7 |
| PNPLA4 | patatin-like phospholipase domain containing 4 |
| PPARD | peroxisome proliferator-activated receptor delta |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) |
| PPFIBP2 | PTPRF interacting protein, binding protein 2 (liprin beta 2) |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C |
| PTCH1 | patched 1 |
| RAP1GAP | RAP1 GTPase activating protein |
| RNF216 | ring finger protein 216 |
| RPS2 | ribosomal protein S2 |
| SALL2 | spalt-like transcription factor 2 |
| SFI1 | Sfi1 homolog, spindle assembly associated (yeast) |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 |
| SLC8B1 | solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 |
| SLITRK5 | SLIT and NTRK-like family, member 5 |
| SMYD2 | SET and MYND domain containing 2 |
| SOGA1 | suppressor of glucose, autophagy associated 1 |
| SPATA2L | spermatogenesis associated 2-like |
| SPN | sialophorin |
| SRD5A3 | steroid 5 alpha-reductase 3 |
| ST5 | suppression of tumorigenicity 5 |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| STOML1 | stomatin (EPB72)-like 1 |
| SULT1A2 | sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) |
| TBC1D4 | TBC1 domain family, member 4 |
| TCP11L1 | t-complex 11, testis-specific-like 1 |
| TEX261 | testis expressed 261 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 |
| TLE4 | transducin-like enhancer of split 4 |
| TMEM134 | transmembrane protein 134 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 |
| TNFRSF12A | tumor necrosis factor receptor superfamily, member 12A |
| TPD52 | tumor protein D52 |
| TRAF3 | TNF receptor-associated factor 3 |
| TRIM33 | tripartite motif containing 33 |
| TSPAN2 | tetraspanin 2 |
| TWIST1 | twist family bHLH transcription factor 1 |
| UAP1L1 | UDP-N-acetylglucosamine pyrophosphorylase 1 like 1 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 |
| USP34 | ubiquitin specific peptidase 34 |
| VPS13D | vacuolar protein sorting 13 homolog D (S. cerevisiae) |
| ZFYVE9 | zinc finger, FYVE domain containing 9 |
| ZMYM2 | zinc finger, MYM-type 2 |
| ZNF444 | zinc finger protein 444 |
| Symbol | Name |
|---|---|
| ACYP2 | acylphosphatase 2, muscle type |
| ADAP2 | ArfGAP with dual PH domains 2 |
| ADTRP | androgen-dependent TFPI-regulating protein |
| ANKHD1 | ankyrin repeat and KH domain containing 1 |
| AP4M1 | adaptor-related protein complex 4, mu 1 subunit |
| ASGR2 | asialoglycoprotein receptor 2 |
| ATAD3A | ATPase family, AAA domain containing 3A |
| ATP6V0E2 | ATPase, H+ transporting V0 subunit e2 |
| AXIN1 | axin 1 |
| B3GNT2 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 |
| BPGM | 2,3-bisphosphoglycerate mutase |
| C11ORF49 | chromosome 11 open reading frame 49 |
| C17ORF70 | chromosome 17 open reading frame 70 |
| C1ORF109 | chromosome 1 open reading frame 109 |
| C1ORF56 | chromosome 1 open reading frame 56 |
| C22ORF46 | chromosome 22 open reading frame 46 |
| C5 | complement component 5 |
| C5ORF45 | chromosome 5 open reading frame 45 |
| C6ORF47 | chromosome 6 open reading frame 47 |
| C8ORF44 | chromosome 8 open reading frame 44 |
| CENPT | centromere protein T |
| CEP170B | centrosomal protein 170B |
| CHRNA10 | cholinergic receptor, nicotinic, alpha 10 (neuronal) |
| CNN2 | calponin 2 |
| COG7 | component of oligomeric golgi complex 7 |
| CTNNBIP1 | catenin, beta interacting protein 1 |
| CWC25 | CWC25 spliceosome-associated protein homolog (S. cerevisiae) |
| DEAF1 | DEAF1 transcription factor |
| DHRS7B | dehydrogenase/reductase (SDR family) member 7B |
| ECI2 | enoyl-CoA delta isomerase 2 |
| EEF1A2 | eukaryotic translation elongation factor 1 alpha 2 |
| ERI3 | ERI1 exoribonuclease family member 3 |
| ERMP1 | endoplasmic reticulum metallopeptidase 1 |
| EVI2B | ecotropic viral integration site 2B |
| EXOC5 | exocyst complex component 5 |
| FAM206A | family with sequence similarity 206, member A |
| FCHO1 | FCH domain only 1 |
| FEM1C | fem-1 homolog c (C. elegans) |
| FHL3 | four and a half LIM domains 3 |
| FKBPL | FK506 binding protein like |
| GDAP2 | ganglioside induced differentiation associated protein 2 |
| GFOD1 | glucose-fructose oxidoreductase domain containing 1 |
| GOLGA8B | golgin A8 family, member B |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 |
| IFITM3 | interferon induced transmembrane protein 3 |
| IFT46 | intraflagellar transport 46 |
| JMJD4 | jumonji domain containing 4 |
| JUP | junction plakoglobin |
| KAT2A | K(lysine) acetyltransferase 2A |
| KCTD7 | potassium channel tetramerization domain containing 7 |
| KDM5C | lysine (K)-specific demethylase 5C |
| KLHL26 | kelch-like family member 26 |
| LILRB4 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4 |
| LRRK1 | leucine-rich repeat kinase 1 |
| MBD5 | methyl-CpG binding domain protein 5 |
| MBTD1 | mbt domain containing 1 |
| MDM4 | MDM4, p53 regulator |
| MIR22HG | MIR22 host gene |
| MST1 | macrophage stimulating 1 |
| N4BP2L2-IT2 | N4BPL2 intronic transcript 2 |
| NPFFR1 | neuropeptide FF receptor 1 |
| PAQR6 | progestin and adipoQ receptor family member VI |
| PARG | poly (ADP-ribose) glycohydrolase |
| PARPBP | PARP1 binding protein |
| PBLD | phenazine biosynthesis-like protein domain containing |
| PDK1 | pyruvate dehydrogenase kinase, isozyme 1 |
| PDLIM2 | PDZ and LIM domain 2 (mystique) |
| PMCH | pro-melanin-concentrating hormone |
| PRR14L | proline rich 14-like |
| PTTG1 | pituitary tumor-transforming 1 |
| QTRT1 | queuine tRNA-ribosyltransferase 1 |
| R3HCC1L | R3H domain and coiled-coil containing 1-like |
| RNF141 | ring finger protein 141 |
| RNF25 | ring finger protein 25 |
| SENP2 | SUMO1/sentrin/SMT3 specific peptidase 2 |
| SLC29A3 | solute carrier family 29 (equilibrative nucleoside transporter), member 3 |
| SLC2A9 | solute carrier family 2 (facilitated glucose transporter), member 9 |
| SLC39A1 | solute carrier family 39 (zinc transporter), member 1 |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 |
| SNX16 | sorting nexin 16 |
| STEAP3 | STEAP family member 3, metalloreductase |
| TET3 | tet methylcytosine dioxygenase 3 |
| TMOD3 | tropomodulin 3 (ubiquitous) |
| TNNT1 | troponin T type 1 (skeletal, slow) |
| TOLLIP | toll interacting protein |
| TUBA3C | tubulin, alpha 3c |
| UBQLN4 | ubiquilin 4 |
| UNC93B1 | unc-93 homolog B1 (C. elegans) |
| VASH1 | vasohibin 1 |
| WT1-AS | WT1 antisense RNA |
| ZC2HC1A | zinc finger, C2HC-type containing 1A |
| ZHX2 | zinc fingers and homeoboxes 2 |
| ZNF230 | zinc finger protein 230 |
| ZNF280D | zinc finger protein 280D |
| ZNF37BP | zinc finger protein 37B, pseudogene |
| ZNF574 | zinc finger protein 574 |
| ZW10 | zw10 kinetochore protein |
