| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the 3-hydroxy-DL-kynurenine-2654 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 |
| AGRP | agouti related neuropeptide |
| AKAP11 | A kinase (PRKA) anchor protein 11 |
| AKAP7 | A kinase (PRKA) anchor protein 7 |
| ALPPL2 | alkaline phosphatase, placental-like 2 |
| ARHGAP35 | Rho GTPase activating protein 35 |
| ASIC1 | acid sensing (proton gated) ion channel 1 |
| BAIAP3 | BAI1-associated protein 3 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A |
| C10ORF95 | chromosome 10 open reading frame 95 |
| C1ORF61 | chromosome 1 open reading frame 61 |
| CACNA1A | calcium channel, voltage-dependent, P/Q type, alpha 1A subunit |
| CCL21 | chemokine (C-C motif) ligand 21 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) |
| CHRNA3 | cholinergic receptor, nicotinic, alpha 3 (neuronal) |
| CLEC2B | C-type lectin domain family 2, member B |
| COL1A1 | collagen, type I, alpha 1 |
| CPNE7 | copine VII |
| CSF1 | colony stimulating factor 1 (macrophage) |
| CTSE | cathepsin E |
| ELOVL5 | ELOVL fatty acid elongase 5 |
| ETV7 | ets variant 7 |
| EXOSC1 | exosome component 1 |
| FBXO41 | F-box protein 41 |
| FGFR1 | fibroblast growth factor receptor 1 |
| FOSL2 | FOS-like antigen 2 |
| FOXP3 | forkhead box P3 |
| FRMD4B | FERM domain containing 4B |
| FSCN1 | fascin actin-bundling protein 1 |
| GALNT3 | polypeptide N-acetylgalactosaminyltransferase 3 |
| GATA4 | GATA binding protein 4 |
| GDPD5 | glycerophosphodiester phosphodiesterase domain containing 5 |
| GPSM3 | G-protein signaling modulator 3 |
| GSTM5 | glutathione S-transferase mu 5 |
| HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 |
| HOXA4 | homeobox A4 |
| HS6ST1 | heparan sulfate 6-O-sulfotransferase 1 |
| HSD17B14 | hydroxysteroid (17-beta) dehydrogenase 14 |
| IGL | immunoglobulin lambda locus |
| IL1RAPL2 | interleukin 1 receptor accessory protein-like 2 |
| INPP5B | inositol polyphosphate-5-phosphatase, 75kDa |
| IQSEC2 | IQ motif and Sec7 domain 2 |
| KIF1C | kinesin family member 1C |
| KIR2DS1 | killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1 |
| KRT31 | keratin 31, type I |
| LIME1 | Lck interacting transmembrane adaptor 1 |
| LSS | lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) |
| LY9 | lymphocyte antigen 9 |
| MARK4 | MAP/microtubule affinity-regulating kinase 4 |
| MGAT2 | mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase |
| MINK1 | misshapen-like kinase 1 |
| MRC2 | mannose receptor, C type 2 |
| MSX2 | msh homeobox 2 |
| MYLK | myosin light chain kinase |
| NCOA2 | nuclear receptor coactivator 2 |
| NLE1 | notchless homolog 1 (Drosophila) |
| NOP16 | NOP16 nucleolar protein |
| NPPA | natriuretic peptide A |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| NRG2 | neuregulin 2 |
| NRIP3 | nuclear receptor interacting protein 3 |
| OR2F1 | olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene) |
| OTUB2 | OTU deubiquitinase, ubiquitin aldehyde binding 2 |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PIPOX | pipecolic acid oxidase |
| POLM | polymerase (DNA directed), mu |
| PON1 | paraoxonase 1 |
| PPP5C | protein phosphatase 5, catalytic subunit |
| PRRG4 | proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) |
| RASAL2 | RAS protein activator like 2 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 |
| RND1 | Rho family GTPase 1 |
| RTN2 | reticulon 2 |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SCAI | suppressor of cancer cell invasion |
| SDC2 | syndecan 2 |
| SEC14L4 | SEC14-like 4 (S. cerevisiae) |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
| SERPINA10 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10 |
| SGCD | sarcoglycan, delta (35kDa dystrophin-associated glycoprotein) |
| SLC25A21 | solute carrier family 25 (mitochondrial oxoadipate carrier), member 21 |
| SLN | sarcolipin |
| SNRK | SNF related kinase |
| SNW1 | SNW domain containing 1 |
| SPEG | SPEG complex locus |
| SPHK2 | sphingosine kinase 2 |
| SPTLC3 | serine palmitoyltransferase, long chain base subunit 3 |
| SWAP70 | SWAP switching B-cell complex 70kDa subunit |
| TCEB3B | transcription elongation factor B polypeptide 3B (elongin A2) |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) |
| TGM2 | transglutaminase 2 |
| TP53AIP1 | tumor protein p53 regulated apoptosis inducing protein 1 |
| TTLL5 | tubulin tyrosine ligase-like family member 5 |
| UTRN | utrophin |
| VAC14 | Vac14 homolog (S. cerevisiae) |
| VEGFA | vascular endothelial growth factor A |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) |
| WHSC1L1 | Wolf-Hirschhorn syndrome candidate 1-like 1 |
| ZC3H13 | zinc finger CCCH-type containing 13 |
| Symbol | Name |
|---|---|
| ABCB7 | ATP-binding cassette, sub-family B (MDR/TAP), member 7 |
| ABHD4 | abhydrolase domain containing 4 |
| ACAD10 | acyl-CoA dehydrogenase family, member 10 |
| ANXA1 | annexin A1 |
| ARRB1 | arrestin, beta 1 |
| ARSB | arylsulfatase B |
| C12ORF4 | chromosome 12 open reading frame 4 |
| C17ORF80 | chromosome 17 open reading frame 80 |
| C19ORF73 | chromosome 19 open reading frame 73 |
| CABYR | calcium binding tyrosine-(Y)-phosphorylation regulated |
| CASD1 | CAS1 domain containing 1 |
| CLDN15 | claudin 15 |
| CRELD1 | cysteine-rich with EGF-like domains 1 |
| CRYBB2P1 | crystallin, beta B2 pseudogene 1 |
| CRYBG3 | beta-gamma crystallin domain containing 3 |
| CUL9 | cullin 9 |
| DGCR11 | DiGeorge syndrome critical region gene 11 (non-protein coding) |
| DHX35 | DEAH (Asp-Glu-Ala-His) box polypeptide 35 |
| DUSP13 | dual specificity phosphatase 13 |
| DZANK1 | double zinc ribbon and ankyrin repeat domains 1 |
| ELP3 | elongator acetyltransferase complex subunit 3 |
| ENTPD7 | ectonucleoside triphosphate diphosphohydrolase 7 |
| EPB41L5 | erythrocyte membrane protein band 4.1 like 5 |
| EXOC5 | exocyst complex component 5 |
| F3 | coagulation factor III (thromboplastin, tissue factor) |
| FAAH | fatty acid amide hydrolase |
| FADS3 | fatty acid desaturase 3 |
| FAM186A | family with sequence similarity 186, member A |
| FBXL2 | F-box and leucine-rich repeat protein 2 |
| FBXL6 | F-box and leucine-rich repeat protein 6 |
| FER | fer (fps/fes related) tyrosine kinase |
| FKBP5 | FK506 binding protein 5 |
| GAMT | guanidinoacetate N-methyltransferase |
| GLS2 | glutaminase 2 (liver, mitochondrial) |
| GRAMD3 | GRAM domain containing 3 |
| HIST1H2AI | histone cluster 1, H2ai |
| HIST1H2BJ | histone cluster 1, H2bj |
| IMPACT | impact RWD domain protein |
| INPPL1 | inositol polyphosphate phosphatase-like 1 |
| IPO8 | importin 8 |
| KIAA0513 | KIAA0513 |
| KIF13B | kinesin family member 13B |
| KIFAP3 | kinesin-associated protein 3 |
| KLF11 | Kruppel-like factor 11 |
| LARP6 | La ribonucleoprotein domain family, member 6 |
| LIG4 | ligase IV, DNA, ATP-dependent |
| LINC00339 | long intergenic non-protein coding RNA 339 |
| LOC390998 | ribosomal protein L10 pseudogene |
| LYPD1 | LY6/PLAUR domain containing 1 |
| LZTFL1 | leucine zipper transcription factor-like 1 |
| MAP1S | microtubule-associated protein 1S |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 |
| MBTPS2 | membrane-bound transcription factor peptidase, site 2 |
| MTMR12 | myotubularin related protein 12 |
| NDE1 | nudE neurodevelopment protein 1 |
| NDUFB7 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa |
| NKX3-2 | NK3 homeobox 2 |
| NPY5R | neuropeptide Y receptor Y5 |
| NRSN2 | neurensin 2 |
| NUBPL | nucleotide binding protein-like |
| PARP16 | poly (ADP-ribose) polymerase family, member 16 |
| PGGT1B | protein geranylgeranyltransferase type I, beta subunit |
| PHLDA3 | pleckstrin homology-like domain, family A, member 3 |
| PLEKHB1 | pleckstrin homology domain containing, family B (evectins) member 1 |
| PMCH | pro-melanin-concentrating hormone |
| PRICKLE3 | prickle homolog 3 (Drosophila) |
| PRKACG | protein kinase, cAMP-dependent, catalytic, gamma |
| PRR14L | proline rich 14-like |
| PRRG1 | proline rich Gla (G-carboxyglutamic acid) 1 |
| PTPN9 | protein tyrosine phosphatase, non-receptor type 9 |
| QTRT1 | queuine tRNA-ribosyltransferase 1 |
| RAB11FIP5 | RAB11 family interacting protein 5 (class I) |
| RAC3 | ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) |
| RFTN1 | raftlin, lipid raft linker 1 |
| RNASEL | ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) |
| RNF122 | ring finger protein 122 |
| SKA1 | spindle and kinetochore associated complex subunit 1 |
| SMPDL3B | sphingomyelin phosphodiesterase, acid-like 3B |
| SPINK4 | serine peptidase inhibitor, Kazal type 4 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 |
| SPRYD7 | SPRY domain containing 7 |
| STK16 | serine/threonine kinase 16 |
| TCHH | trichohyalin |
| TCTA | T-cell leukemia translocation altered |
| TMEM2 | transmembrane protein 2 |
| TMEM260 | transmembrane protein 260 |
| TNFRSF14 | tumor necrosis factor receptor superfamily, member 14 |
| TNKS2 | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 |
| TUT1 | terminal uridylyl transferase 1, U6 snRNA-specific |
| UAP1L1 | UDP-N-acetylglucosamine pyrophosphorylase 1 like 1 |
| UBQLN4 | ubiquilin 4 |
| ZNF324 | zinc finger protein 324 |
| ZNF34 | zinc finger protein 34 |
| ZNF510 | zinc finger protein 510 |
| ZNF571 | zinc finger protein 571 |
| ZNF654 | zinc finger protein 654 |
| ZNF74 | zinc finger protein 74 |
| ZSCAN26 | zinc finger and SCAN domain containing 26 |
