| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the 3-hydroxy-DL-kynurenine-5276 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACTN1 | actinin, alpha 1 |
| ADCK2 | aarF domain containing kinase 2 |
| AHSP | alpha hemoglobin stabilizing protein |
| AKAP8L | A kinase (PRKA) anchor protein 8-like |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 |
| BAX | BCL2-associated X protein |
| BCL7A | B-cell CLL/lymphoma 7A |
| BST2 | bone marrow stromal cell antigen 2 |
| C6ORF10 | chromosome 6 open reading frame 10 |
| CALML5 | calmodulin-like 5 |
| CAMK2B | calcium/calmodulin-dependent protein kinase II beta |
| CARTPT | CART prepropeptide |
| CD3D | CD3d molecule, delta (CD3-TCR complex) |
| CD52 | CD52 molecule |
| CHRNB2 | cholinergic receptor, nicotinic, beta 2 (neuronal) |
| COBLL1 | cordon-bleu WH2 repeat protein-like 1 |
| COL1A1 | collagen, type I, alpha 1 |
| CRMP1 | collapsin response mediator protein 1 |
| CUEDC1 | CUE domain containing 1 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 |
| DIO2 | deiodinase, iodothyronine, type II |
| DLC1 | DLC1 Rho GTPase activating protein |
| EFNB3 | ephrin-B3 |
| F2RL2 | coagulation factor II (thrombin) receptor-like 2 |
| FMO5 | flavin containing monooxygenase 5 |
| FRMD4A | FERM domain containing 4A |
| GGT1 | gamma-glutamyltransferase 1 |
| GPR137 | G protein-coupled receptor 137 |
| GPR143 | G protein-coupled receptor 143 |
| GREB1 | growth regulation by estrogen in breast cancer 1 |
| GTF2F1 | general transcription factor IIF, polypeptide 1, 74kDa |
| HCG4 | HLA complex group 4 (non-protein coding) |
| HIST1H1D | histone cluster 1, H1d |
| HIST1H4C | histone cluster 1, H4c |
| HMOX1 | heme oxygenase 1 |
| IFI27 | interferon, alpha-inducible protein 27 |
| IFI35 | interferon-induced protein 35 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IFITM1 | interferon induced transmembrane protein 1 |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| ISG15 | ISG15 ubiquitin-like modifier |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) |
| JUN | jun proto-oncogene |
| KAT6A | K(lysine) acetyltransferase 6A |
| KHSRP | KH-type splicing regulatory protein |
| KLF13 | Kruppel-like factor 13 |
| MED25 | mediator complex subunit 25 |
| MEF2D | myocyte enhancer factor 2D |
| MID1 | midline 1 |
| NFATC1 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
| NME5 | NME/NM23 family member 5 |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| NYNRIN | NYN domain and retroviral integrase containing |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa |
| PADI3 | peptidyl arginine deiminase, type III |
| PBX2 | pre-B-cell leukemia homeobox 2 |
| PDGFA | platelet-derived growth factor alpha polypeptide |
| PHF20L1 | PHD finger protein 20-like 1 |
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| PLAT | plasminogen activator, tissue |
| PPP1R10 | protein phosphatase 1, regulatory subunit 10 |
| PQLC2 | PQ loop repeat containing 2 |
| PRKAB2 | protein kinase, AMP-activated, beta 2 non-catalytic subunit |
| PVT1 | Pvt1 oncogene (non-protein coding) |
| RABGAP1L | RAB GTPase activating protein 1-like |
| RBM5 | RNA binding motif protein 5 |
| REEP2 | receptor accessory protein 2 |
| REST | RE1-silencing transcription factor |
| RUNX1 | runt-related transcription factor 1 |
| SCAPER | S-phase cyclin A-associated protein in the ER |
| SCN5A | sodium channel, voltage gated, type V alpha subunit |
| SDC3 | syndecan 3 |
| SF1 | splicing factor 1 |
| SFRP4 | secreted frizzled-related protein 4 |
| SH3BP2 | SH3-domain binding protein 2 |
| SLC1A2 | solute carrier family 1 (glial high affinity glutamate transporter), member 2 |
| SLC1A4 | solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 |
| SLC1A7 | solute carrier family 1 (glutamate transporter), member 7 |
| SLC35E2 | solute carrier family 35, member E2 |
| SLC9A3R2 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2 |
| SMG7 | SMG7 nonsense mediated mRNA decay factor |
| SP100 | SP100 nuclear antigen |
| STK24 | serine/threonine kinase 24 |
| TBC1D2 | TBC1 domain family, member 2 |
| TBR1 | T-box, brain, 1 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) |
| TNPO2 | transportin 2 |
| TPSG1 | tryptase gamma 1 |
| TRD | T cell receptor delta locus |
| UNC119 | unc-119 homolog (C. elegans) |
| USP2 | ubiquitin specific peptidase 2 |
| VAPB | VAMP (vesicle-associated membrane protein)-associated protein B and C |
| ZFHX2 | zinc finger homeobox 2 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 |
| ZNF124 | zinc finger protein 124 |
| ZSWIM1 | zinc finger, SWIM-type containing 1 |
| Symbol | Name |
|---|---|
| ABHD17B | abhydrolase domain containing 17B |
| ADTRP | androgen-dependent TFPI-regulating protein |
| ARHGEF17 | Rho guanine nucleotide exchange factor (GEF) 17 |
| ATF3 | activating transcription factor 3 |
| BBC3 | BCL2 binding component 3 |
| BTF3P11 | basic transcription factor 3 pseudogene 11 |
| C4ORF29 | chromosome 4 open reading frame 29 |
| CAMK4 | calcium/calmodulin-dependent protein kinase IV |
| CEP295 | centrosomal protein 295kDa |
| CHRNA9 | cholinergic receptor, nicotinic, alpha 9 (neuronal) |
| CIDEC | cell death-inducing DFFA-like effector c |
| CLCF1 | cardiotrophin-like cytokine factor 1 |
| CLCN6 | chloride channel, voltage-sensitive 6 |
| CRY2 | cryptochrome circadian clock 2 |
| CYP17A1 | cytochrome P450, family 17, subfamily A, polypeptide 1 |
| DNAH17 | dynein, axonemal, heavy chain 17 |
| DNM3 | dynamin 3 |
| ERCC4 | excision repair cross-complementation group 4 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| ETNK2 | ethanolamine kinase 2 |
| FGD1 | FYVE, RhoGEF and PH domain containing 1 |
| FLCN | folliculin |
| FRMD1 | FERM domain containing 1 |
| GALNT12 | polypeptide N-acetylgalactosaminyltransferase 12 |
| GCNT1 | glucosaminyl (N-acetyl) transferase 1, core 2 |
| GINS4 | GINS complex subunit 4 (Sld5 homolog) |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
| GPR19 | G protein-coupled receptor 19 |
| GPR27 | G protein-coupled receptor 27 |
| GRB7 | growth factor receptor-bound protein 7 |
| GSTM2 | glutathione S-transferase mu 2 (muscle) |
| GSTP1 | glutathione S-transferase pi 1 |
| GUCY1A2 | guanylate cyclase 1, soluble, alpha 2 |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HAMP | hepcidin antimicrobial peptide |
| HIST1H3G | histone cluster 1, H3g |
| HIST1H4D | histone cluster 1, H4d |
| HIST1H4E | histone cluster 1, H4e |
| HLA-DMA | major histocompatibility complex, class II, DM alpha |
| KLHL25 | kelch-like family member 25 |
| KPNA5 | karyopherin alpha 5 (importin alpha 6) |
| LGALS4 | lectin, galactoside-binding, soluble, 4 |
| LIN7A | lin-7 homolog A (C. elegans) |
| LRRC37A3 | leucine rich repeat containing 37, member A3 |
| MAPKBP1 | mitogen-activated protein kinase binding protein 1 |
| MTCP1 | mature T-cell proliferation 1 |
| MYOZ3 | myozenin 3 |
| NOS1AP | nitric oxide synthase 1 (neuronal) adaptor protein |
| OR12D2 | olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene) |
| OR2B6 | olfactory receptor, family 2, subfamily B, member 6 |
| OSMR | oncostatin M receptor |
| OVGP1 | oviductal glycoprotein 1, 120kDa |
| OVOL1 | ovo-like zinc finger 1 |
| PADI1 | peptidyl arginine deiminase, type I |
| PCDHA5 | protocadherin alpha 5 |
| PCDHB13 | protocadherin beta 13 |
| PIGN | phosphatidylinositol glycan anchor biosynthesis, class N |
| PIPOX | pipecolic acid oxidase |
| PREX2 | phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 |
| PRR4 | proline rich 4 (lacrimal) |
| PRRG4 | proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) |
| PRSS53 | protease, serine, 53 |
| RAB3D | RAB3D, member RAS oncogene family |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 |
| RASSF2 | Ras association (RalGDS/AF-6) domain family member 2 |
| RGS2 | regulator of G-protein signaling 2 |
| RHOBTB2 | Rho-related BTB domain containing 2 |
| RLN1 | relaxin 1 |
| RNF125 | ring finger protein 125, E3 ubiquitin protein ligase |
| RNF39 | ring finger protein 39 |
| S100A9 | S100 calcium binding protein A9 |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SCGB2A2 | secretoglobin, family 2A, member 2 |
| SECTM1 | secreted and transmembrane 1 |
| SLC9A5 | solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5 |
| SP140L | SP140 nuclear body protein-like |
| SPRYD7 | SPRY domain containing 7 |
| SSR3 | signal sequence receptor, gamma (translocon-associated protein gamma) |
| STRN | striatin, calmodulin binding protein |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| TEP1 | telomerase-associated protein 1 |
| TEX40 | testis expressed 40 |
| TMPRSS3 | transmembrane protease, serine 3 |
| TNFSF18 | tumor necrosis factor (ligand) superfamily, member 18 |
| TRAIP | TRAF interacting protein |
| TRMT2B | tRNA methyltransferase 2 homolog B (S. cerevisiae) |
| TRMT44 | tRNA methyltransferase 44 homolog (S. cerevisiae) |
| TYRP1 | tyrosinase-related protein 1 |
| UBQLN4 | ubiquilin 4 |
| VIM | vimentin |
| VLDLR | very low density lipoprotein receptor |
| XRCC2 | X-ray repair complementing defective repair in Chinese hamster cells 2 |
| ZNF480 | zinc finger protein 480 |
| ZNF484 | zinc finger protein 484 |
| ZNF652 | zinc finger protein 652 |
| ZNF747 | zinc finger protein 747 |
| ZNF862 | zinc finger protein 862 |
