| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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195 genes differentially expressed following the 3-hydroxy-DL-kynurenine-5641 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AAGAB | alpha- and gamma-adaptin binding protein |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 |
| ACOX2 | acyl-CoA oxidase 2, branched chain |
| ACSL5 | acyl-CoA synthetase long-chain family member 5 |
| ADAM3A | ADAM metallopeptidase domain 3A (pseudogene) |
| AHSP | alpha hemoglobin stabilizing protein |
| AIM2 | absent in melanoma 2 |
| ALS2CL | ALS2 C-terminal like |
| ANGEL2 | angel homolog 2 (Drosophila) |
| APOC4 | apolipoprotein C-IV |
| B3GNT4 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A |
| C1QL1 | complement component 1, q subcomponent-like 1 |
| C8A | complement component 8, alpha polypeptide |
| CALD1 | caldesmon 1 |
| CAMKK2 | calcium/calmodulin-dependent protein kinase kinase 2, beta |
| CD28 | CD28 molecule |
| CD47 | CD47 molecule |
| CDC14B | cell division cycle 14B |
| CLEC2B | C-type lectin domain family 2, member B |
| CTIF | CBP80/20-dependent translation initiation factor |
| CXORF21 | chromosome X open reading frame 21 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 |
| CYP4F8 | cytochrome P450, family 4, subfamily F, polypeptide 8 |
| DCHS2 | dachsous cadherin-related 2 |
| DCTN1 | dynactin 1 |
| DDX28 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 28 |
| DFNB31 | deafness, autosomal recessive 31 |
| DGCR8 | DGCR8 microprocessor complex subunit |
| DNAJC4 | DnaJ (Hsp40) homolog, subfamily C, member 4 |
| EFNB3 | ephrin-B3 |
| EPHB2 | EPH receptor B2 |
| EYA3 | EYA transcriptional coactivator and phosphatase 3 |
| FBXO40 | F-box protein 40 |
| FGF13 | fibroblast growth factor 13 |
| FOLR2 | folate receptor 2 (fetal) |
| FOXP3 | forkhead box P3 |
| FRMD4B | FERM domain containing 4B |
| FSTL3 | follistatin-like 3 (secreted glycoprotein) |
| GNG7 | guanine nucleotide binding protein (G protein), gamma 7 |
| GPR85 | G protein-coupled receptor 85 |
| IGFBP5 | insulin-like growth factor binding protein 5 |
| IGHA1 | immunoglobulin heavy constant alpha 1 |
| IL24 | interleukin 24 |
| INSR | insulin receptor |
| KCNAB1 | potassium channel, voltage gated subfamily A regulatory beta subunit 1 |
| KCNH2 | potassium channel, voltage gated eag related subfamily H, member 2 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 |
| KIF13A | kinesin family member 13A |
| KSR1 | kinase suppressor of ras 1 |
| LPL | lipoprotein lipase |
| LYVE1 | lymphatic vessel endothelial hyaluronan receptor 1 |
| MAOB | monoamine oxidase B |
| MBD3 | methyl-CpG binding domain protein 3 |
| MCTP2 | multiple C2 domains, transmembrane 2 |
| MMP25 | matrix metallopeptidase 25 |
| MOB3B | MOB kinase activator 3B |
| MYH14 | myosin, heavy chain 14, non-muscle |
| NEK9 | NIMA-related kinase 9 |
| NOX5 | NADPH oxidase, EF-hand calcium binding domain 5 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 |
| PARVA | parvin, alpha |
| PBX2 | pre-B-cell leukemia homeobox 2 |
| PCDH1 | protocadherin 1 |
| PER1 | period circadian clock 1 |
| PIGO | phosphatidylinositol glycan anchor biosynthesis, class O |
| PKD2L2 | polycystic kidney disease 2-like 2 |
| PLA2G1B | phospholipase A2, group IB (pancreas) |
| PML | promyelocytic leukemia |
| PRND | prion protein 2 (dublet) |
| PROZ | protein Z, vitamin K-dependent plasma glycoprotein |
| RAPGEF5 | Rap guanine nucleotide exchange factor (GEF) 5 |
| RELN | reelin |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RNF208 | ring finger protein 208 |
| RPGRIP1L | RPGRIP1-like |
| RPS6KA6 | ribosomal protein S6 kinase, 90kDa, polypeptide 6 |
| RUNDC3A | RUN domain containing 3A |
| SETBP1 | SET binding protein 1 |
| SH2D3A | SH2 domain containing 3A |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 |
| SIGLEC8 | sialic acid binding Ig-like lectin 8 |
| SIRT5 | sirtuin 5 |
| SIT1 | signaling threshold regulating transmembrane adaptor 1 |
| SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8 |
| SPHK2 | sphingosine kinase 2 |
| SPP1 | secreted phosphoprotein 1 |
| SPRR2B | small proline-rich protein 2B |
| SRSF7 | serine/arginine-rich splicing factor 7 |
| STAC | SH3 and cysteine rich domain |
| TBX6 | T-box 6 |
| TNK2 | tyrosine kinase, non-receptor, 2 |
| TRIM10 | tripartite motif containing 10 |
| TUBA3C | tubulin, alpha 3c |
| VPS45 | vacuolar protein sorting 45 homolog (S. cerevisiae) |
| ZNF440 | zinc finger protein 440 |
| ZNF639 | zinc finger protein 639 |
| ZNF862 | zinc finger protein 862 |
| ZSCAN2 | zinc finger and SCAN domain containing 2 |
| Symbol | Name |
|---|---|
| ALOX15 | arachidonate 15-lipoxygenase |
| ALPK1 | alpha-kinase 1 |
| ANXA2P3 | annexin A2 pseudogene 3 |
| ATAT1 | alpha tubulin acetyltransferase 1 |
| C11ORF63 | chromosome 11 open reading frame 63 |
| C1ORF159 | chromosome 1 open reading frame 159 |
| CAPN15 | calpain 15 |
| CCDC134 | coiled-coil domain containing 134 |
| CFD | complement factor D (adipsin) |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 |
| CHST8 | carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8 |
| CLSTN2 | calsyntenin 2 |
| CNKSR1 | connector enhancer of kinase suppressor of Ras 1 |
| CPSF3L | cleavage and polyadenylation specific factor 3-like |
| CRIP1 | cysteine-rich protein 1 (intestinal) |
| CSTA | cystatin A (stefin A) |
| CTC1 | CTS telomere maintenance complex component 1 |
| CYP2B7P | cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene |
| DDX58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 |
| DEAF1 | DEAF1 transcription factor |
| DIXDC1 | DIX domain containing 1 |
| DRD1 | dopamine receptor D1 |
| EPN1 | epsin 1 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| ETV6 | ets variant 6 |
| FAM169A | family with sequence similarity 169, member A |
| FBXL7 | F-box and leucine-rich repeat protein 7 |
| FKBP1B | FK506 binding protein 1B, 12.6 kDa |
| FRK | fyn-related Src family tyrosine kinase |
| FRMD1 | FERM domain containing 1 |
| GADD45G | growth arrest and DNA-damage-inducible, gamma |
| GEMIN8 | gem (nuclear organelle) associated protein 8 |
| GFI1 | growth factor independent 1 transcription repressor |
| GMPR | guanosine monophosphate reductase |
| GNA15 | guanine nucleotide binding protein (G protein), alpha 15 (Gq class) |
| GNAT2 | guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2 |
| GNG3 | guanine nucleotide binding protein (G protein), gamma 3 |
| GPR27 | G protein-coupled receptor 27 |
| GRB7 | growth factor receptor-bound protein 7 |
| GTPBP2 | GTP binding protein 2 |
| HAMP | hepcidin antimicrobial peptide |
| HELZ | helicase with zinc finger |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 |
| HOXC4 | homeobox C4 |
| IL2 | interleukin 2 |
| KBTBD11 | kelch repeat and BTB (POZ) domain containing 11 |
| KCNK12 | potassium channel, two pore domain subfamily K, member 12 |
| KCTD7 | potassium channel tetramerization domain containing 7 |
| LIN7A | lin-7 homolog A (C. elegans) |
| LLPH | LLP homolog, long-term synaptic facilitation (Aplysia) |
| MALL | mal, T-cell differentiation protein-like |
| MNS1 | meiosis-specific nuclear structural 1 |
| MSI1 | musashi RNA-binding protein 1 |
| MTA2 | metastasis associated 1 family, member 2 |
| MTERF1 | mitochondrial transcription termination factor 1 |
| N4BP3 | NEDD4 binding protein 3 |
| PDE6C | phosphodiesterase 6C, cGMP-specific, cone, alpha prime |
| PGR | progesterone receptor |
| PHC1 | polyhomeotic homolog 1 (Drosophila) |
| PLA2G3 | phospholipase A2, group III |
| PNPLA6 | patatin-like phospholipase domain containing 6 |
| RFXAP | regulatory factor X-associated protein |
| RNF2 | ring finger protein 2 |
| RPL10L | ribosomal protein L10-like |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| S100A7 | S100 calcium binding protein A7 |
| SCN1B | sodium channel, voltage gated, type I beta subunit |
| SLC12A8 | solute carrier family 12, member 8 |
| SLC12A9 | solute carrier family 12, member 9 |
| SLC22A14 | solute carrier family 22, member 14 |
| SLC22A18AS | solute carrier family 22 (organic cation transporter), member 18 antisense |
| SLC29A3 | solute carrier family 29 (equilibrative nucleoside transporter), member 3 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 |
| SLC5A5 | solute carrier family 5 (sodium/iodide cotransporter), member 5 |
| SLIT2 | slit homolog 2 (Drosophila) |
| STK16 | serine/threonine kinase 16 |
| SYNC | syncoilin, intermediate filament protein |
| TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) |
| TFF2 | trefoil factor 2 |
| TGFBR1 | transforming growth factor, beta receptor 1 |
| THRAP3 | thyroid hormone receptor associated protein 3 |
| TLN1 | talin 1 |
| TPST2 | tyrosylprotein sulfotransferase 2 |
| TRAF2 | TNF receptor-associated factor 2 |
| UNC93B1 | unc-93 homolog B1 (C. elegans) |
| USP19 | ubiquitin specific peptidase 19 |
| VEZT | vezatin, adherens junctions transmembrane protein |
| VPS9D1 | VPS9 domain containing 1 |
| VWA1 | von Willebrand factor A domain containing 1 |
| XYLT2 | xylosyltransferase II |
| ZNF205 | zinc finger protein 205 |
| ZNF34 | zinc finger protein 34 |
| ZNF446 | zinc finger protein 446 |
| ZNF484 | zinc finger protein 484 |
| ZNF516 | zinc finger protein 516 |
| ZNF696 | zinc finger protein 696 |
