4-hydroxy-2-nonenal Gene Set

Dataset CTD Gene-Chemical Interactions
Category physical interactions
Type chemical
External Link http://ctdbase.org/detail.go?type=chem&acc=C027576
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Genes

130 genes/proteins interacting with the chemical 4-hydroxy-2-nonenal from the curated CTD Gene-Chemical Interactions dataset.

Symbol Name
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
ACTA1 actin, alpha 1, skeletal muscle
ACTB actin, beta
ACTN1 actinin, alpha 1
ACTN4 actinin, alpha 4
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AKR1A1 aldo-keto reductase family 1, member A1 (aldehyde reductase)
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AKR1C3 aldo-keto reductase family 1, member C3
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase)
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
ALDH3B1 aldehyde dehydrogenase 3 family, member B1
ALDH7A1 aldehyde dehydrogenase 7 family, member A1
ALDOA aldolase A, fructose-bisphosphate
APC adenomatous polyposis coli
APOA1 apolipoprotein A-I
APP amyloid beta (A4) precursor protein
ATF3 activating transcription factor 3
ATF4 activating transcription factor 4
ATF6 activating transcription factor 6
ATP5A1 ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle
BAX BCL2-associated X protein
CA2 carbonic anhydrase II
CALCA calcitonin-related polypeptide alpha
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast)
CAPZB capping protein (actin filament) muscle Z-line, beta
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP9 caspase 9, apoptosis-related cysteine peptidase
CCL5 chemokine (C-C motif) ligand 5
CCND2 cyclin D2
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CES1 carboxylesterase 1
CES2 carboxylesterase 2
CFL1 cofilin 1 (non-muscle)
COL1A1 collagen, type I, alpha 1
CP ceruloplasmin (ferroxidase)
CREB1 cAMP responsive element binding protein 1
CREBBP CREB binding protein
CSF3 colony stimulating factor 3 (granulocyte)
CXCL10 chemokine (C-X-C motif) ligand 10
CYBB cytochrome b-245, beta polypeptide
CYCS cytochrome c, somatic
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6
CYP2J2 cytochrome P450, family 2, subfamily J, polypeptide 2
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
DDIT3 DNA-damage-inducible transcript 3
DPYSL2 dihydropyrimidinase-like 2
DRD2 dopamine receptor D2
DYNLT3 dynein, light chain, Tctex-type 3
EEF2 eukaryotic translation elongation factor 2
EIF2A eukaryotic translation initiation factor 2A, 65kDa
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3
EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
ENO1 enolase 1, (alpha)
FOS FBJ murine osteosarcoma viral oncogene homolog
FOXO3 forkhead box O3
GAPDH glyceraldehyde-3-phosphate dehydrogenase
GCLC glutamate-cysteine ligase, catalytic subunit
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial
GPX1 glutathione peroxidase 1
GSTA1 glutathione S-transferase alpha 1
GSTA3 glutathione S-transferase alpha 3
GSTA4 glutathione S-transferase alpha 4
GSTM1 glutathione S-transferase mu 1
GSTM2 glutathione S-transferase mu 2 (muscle)
GSTP1 glutathione S-transferase pi 1
H2AFX H2A histone family, member X
H6PD hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
HMOX1 heme oxygenase 1
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
IFNB1 interferon, beta 1, fibroblast
IFNG interferon, gamma
IL2 interleukin 2
IRF3 interferon regulatory factor 3
JUN jun proto-oncogene
LRRC59 leucine rich repeat containing 59
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MAPK8 mitogen-activated protein kinase 8
MMP1 matrix metallopeptidase 1
MMP2 matrix metallopeptidase 2
MMP9 matrix metallopeptidase 9
NFE2L2 nuclear factor, erythroid 2-like 2
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NOS2 nitric oxide synthase 2, inducible
P4HB prolyl 4-hydroxylase, beta polypeptide
PARP1 poly (ADP-ribose) polymerase 1
PHGDH phosphoglycerate dehydrogenase
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
POLH polymerase (DNA directed), eta
POLK polymerase (DNA directed) kappa
POLL polymerase (DNA directed), lambda
PON1 paraoxonase 1
PTGR1 prostaglandin reductase 1
RALBP1 ralA binding protein 1
RB1 retinoblastoma 1
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
REV1 REV1, polymerase (DNA directed)
REV3L REV3-like, polymerase (DNA directed), zeta, catalytic subunit
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
SAMHD1 SAM domain and HD domain 1
SCARB1 scavenger receptor class B, member 1
SERBP1 SERPINE1 mRNA binding protein 1
SIRT1 sirtuin 1
SIRT3 sirtuin 3
SOD2 superoxide dismutase 2, mitochondrial
SRP9 signal recognition particle 9kDa
STK11 serine/threonine kinase 11
TAC1 tachykinin, precursor 1
TLR4 toll-like receptor 4
TNF tumor necrosis factor
TP53 tumor protein p53
TP63 tumor protein p63
TP73 tumor protein p73
TPI1 triosephosphate isomerase 1
TRPA1 transient receptor potential cation channel, subfamily A, member 1
TUBA1B tubulin, alpha 1b
TXN thioredoxin
VDAC2 voltage-dependent anion channel 2
VIM vimentin