4-hydroxyphenazone-1997 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the 4-hydroxyphenazone-1997 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAK1 AP2 associated kinase 1
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2
ABHD3 abhydrolase domain containing 3
AGA aspartylglucosaminidase
AGGF1 angiogenic factor with G patch and FHA domains 1
AP1G2 adaptor-related protein complex 1, gamma 2 subunit
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
ATM ATM serine/threonine kinase
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein)
C14ORF1 chromosome 14 open reading frame 1
C19ORF66 chromosome 19 open reading frame 66
CD164 CD164 molecule, sialomucin
CDK17 cyclin-dependent kinase 17
CENPT centromere protein T
CLEC11A C-type lectin domain family 11, member A
CTH cystathionine gamma-lyase
DCUN1D4 DCN1, defective in cullin neddylation 1, domain containing 4
DNAH3 dynein, axonemal, heavy chain 3
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1
DOPEY2 dopey family member 2
DPYD dihydropyrimidine dehydrogenase
DYRK2 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
EHMT2 euchromatic histone-lysine N-methyltransferase 2
EIF1 eukaryotic translation initiation factor 1
FAM188A family with sequence similarity 188, member A
FAM89B family with sequence similarity 89, member B
FMOD fibromodulin
GAB2 GRB2-associated binding protein 2
GATA2 GATA binding protein 2
GLRX3 glutaredoxin 3
GNAS GNAS complex locus
GSAP gamma-secretase activating protein
HBEGF heparin-binding EGF-like growth factor
HMGB3P1 high mobility group box 3 pseudogene 1
HMOX2 heme oxygenase 2
HOMER1 homer scaffolding protein 1
IDS iduronate 2-sulfatase
IL1R2 interleukin 1 receptor, type II
IRAK3 interleukin-1 receptor-associated kinase 3
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
JAG1 jagged 1
JRKL JRK-like
KANK2 KN motif and ankyrin repeat domains 2
KBTBD4 kelch repeat and BTB (POZ) domain containing 4
KIAA1109 KIAA1109
LDLR low density lipoprotein receptor
LDLRAP1 low density lipoprotein receptor adaptor protein 1
LINC00339 long intergenic non-protein coding RNA 339
LPIN2 lipin 2
LRP12 low density lipoprotein receptor-related protein 12
MGAM maltase-glucoamylase
MLX MLX, MAX dimerization protein
MRPS18A mitochondrial ribosomal protein S18A
MTERF1 mitochondrial transcription termination factor 1
MTF2 metal response element binding transcription factor 2
MTMR2 myotubularin related protein 2
MUM1 melanoma associated antigen (mutated) 1
MXD4 MAX dimerization protein 4
N4BP2L1 NEDD4 binding protein 2-like 1
NBR1 neighbor of BRCA1 gene 1
NDRG2 NDRG family member 2
NREP neuronal regeneration related protein
NUFIP1 nuclear fragile X mental retardation protein interacting protein 1
OVGP1 oviductal glycoprotein 1, 120kDa
PARP16 poly (ADP-ribose) polymerase family, member 16
PAX1 paired box 1
PDS5A PDS5 cohesin associated factor A
PLCL2 phospholipase C-like 2
PPAP2A phosphatidic acid phosphatase type 2A
PRPH peripherin
PVR poliovirus receptor
RABGGTB Rab geranylgeranyltransferase, beta subunit
RAP1GAP RAP1 GTPase activating protein
RFX7 regulatory factor X, 7
RGS1 regulator of G-protein signaling 1
RHBDD3 rhomboid domain containing 3
SAPCD1 suppressor APC domain containing 1
SCYL3 SCY1-like 3 (S. cerevisiae)
SETD2 SET domain containing 2
SLITRK5 SLIT and NTRK-like family, member 5
SRRT serrate, RNA effector molecule
STAP2 signal transducing adaptor family member 2
STX12 syntaxin 12
SUCLG2 succinate-CoA ligase, GDP-forming, beta subunit
SUSD6 sushi domain containing 6
TCF4 transcription factor 4
TERF1 telomeric repeat binding factor (NIMA-interacting) 1
THEM6 thioesterase superfamily member 6
TINF2 TERF1 (TRF1)-interacting nuclear factor 2
TMEM5 transmembrane protein 5
TRD T cell receptor delta locus
TTLL4 tubulin tyrosine ligase-like family member 4
VARS valyl-tRNA synthetase
WASL Wiskott-Aldrich syndrome-like
WDR1 WD repeat domain 1
ZNF154 zinc finger protein 154
ZNF335 zinc finger protein 335

decreased expression

Symbol Name
ABCA11P ATP-binding cassette, sub-family A (ABC1), member 11, pseudogene
ACOT9 acyl-CoA thioesterase 9
ACSL4 acyl-CoA synthetase long-chain family member 4
ADAM23 ADAM metallopeptidase domain 23
ADIPOR2 adiponectin receptor 2
AGO3 argonaute RISC catalytic component 3
ALPK1 alpha-kinase 1
ASXL2 additional sex combs like transcriptional regulator 2
BTNL3 butyrophilin-like 3
C7ORF43 chromosome 7 open reading frame 43
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3
CD151 CD151 molecule (Raph blood group)
CD38 CD38 molecule
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CHD8 chromodomain helicase DNA binding protein 8
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11
CHST5 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5
CIDEC cell death-inducing DFFA-like effector c
CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin
CNPY3 canopy FGF signaling regulator 3
CTRL chymotrypsin-like
DDIT3 DNA-damage-inducible transcript 3
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DRD5 dopamine receptor D5
DVL1 dishevelled segment polarity protein 1
ERCC3 excision repair cross-complementation group 3
FADS2 fatty acid desaturase 2
FBXW4 F-box and WD repeat domain containing 4
GALNS galactosamine (N-acetyl)-6-sulfatase
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GJD2 gap junction protein, delta 2, 36kDa
GMCL1 germ cell-less, spermatogenesis associated 1
GMEB1 glucocorticoid modulatory element binding protein 1
GPATCH3 G patch domain containing 3
H2BFS H2B histone family, member S (pseudogene)
HIRA histone cell cycle regulator
HMG20A high mobility group 20A
IFNA17 interferon, alpha 17
ILK integrin-linked kinase
INO80D INO80 complex subunit D
IRF2BP1 interferon regulatory factor 2 binding protein 1
ITFG1 integrin alpha FG-GAP repeat containing 1
KAT7 K(lysine) acetyltransferase 7
KRI1 KRI1 homolog (S. cerevisiae)
LHFPL2 lipoma HMGIC fusion partner-like 2
LIMD2 LIM domain containing 2
LOC100127972 uncharacterized LOC100127972
LONRF3 LON peptidase N-terminal domain and ring finger 3
MAN2B2 mannosidase, alpha, class 2B, member 2
MAPKBP1 mitogen-activated protein kinase binding protein 1
MFSD12 major facilitator superfamily domain containing 12
MMACHC methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria
MRGBP MRG/MORF4L binding protein
MXRA8 matrix-remodelling associated 8
NDST2 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2
NOD1 nucleotide-binding oligomerization domain containing 1
NOL6 nucleolar protein 6 (RNA-associated)
NT5DC3 5'-nucleotidase domain containing 3
NUBP2 nucleotide binding protein 2
PADI1 peptidyl arginine deiminase, type I
PCNXL4 pecanex-like 4 (Drosophila)
PDSS2 prenyl (decaprenyl) diphosphate synthase, subunit 2
PEX26 peroxisomal biogenesis factor 26
PPM1G protein phosphatase, Mg2+/Mn2+ dependent, 1G
PPP1R14D protein phosphatase 1, regulatory (inhibitor) subunit 14D
PRR14L proline rich 14-like
PSKH1 protein serine kinase H1
PTPN9 protein tyrosine phosphatase, non-receptor type 9
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RIC8A RIC8 guanine nucleotide exchange factor A
SIRT6 sirtuin 6
SKIV2L2 superkiller viralicidic activity 2-like 2 (S. cerevisiae)
SLC25A22 solute carrier family 25 (mitochondrial carrier: glutamate), member 22
SLC4A2 solute carrier family 4 (anion exchanger), member 2
SP140L SP140 nuclear body protein-like
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STRA13 stimulated by retinoic acid 13
TAC3 tachykinin 3
TERT telomerase reverse transcriptase
TESK1 testis-specific kinase 1
TEX40 testis expressed 40
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
TULP4 tubby like protein 4
UBE2O ubiquitin-conjugating enzyme E2O
UNC93B1 unc-93 homolog B1 (C. elegans)
VPS11 vacuolar protein sorting 11 homolog (S. cerevisiae)
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
WNT10B wingless-type MMTV integration site family, member 10B
ZC3H12A zinc finger CCCH-type containing 12A
ZFP36 ZFP36 ring finger protein
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZNF654 zinc finger protein 654
ZNF85 zinc finger protein 85